BIOGRAPHICAL SKETCH
Provide the following information for the key personnel and other significant contributors in the order listed on Form Page 2.Follow this format for each person. DO NOT EXCEED FOUR PAGES.
NAME
Lei Xu, Ph.D. / POSITION TITLE
Research Assistant Professor of Biostatistics
eRA COMMONS USER NAME (credential, e.g., agency login)
xul5
EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.)
INSTITUTION AND LOCATION / DEGREE
(if applicable) / YEAR(s) / FIELD OF STUDY
University of Michigan / Ph.D. / 2007 / Biostatistics
University of Michigan / M.S. / 2004 / Biostatistics
PHS 398/2590 (Rev. 11/07) Page 2 Biographical Sketch Format Page
A. Positions and Honors.
Positions and Employment
2002-2007 Research Assistant, Department of Biostatistics, University of Michigan
2008- Research Assistant Professor, Department of Biostatistics, Vanderbilt University
Honors
2008 John Van Ryzin Award (ENAR Best Student Paper Award)
For paper entitled:”Bayesian Spatial Modeling of fMRI data: a Multiple-Subject Analysis”
B. Selected peer-reviewed publications (in chronological order).
1. Xu L, Johnson TD, Nichols TE, Nee DE. Modeling inter-subject variability in fMRI activation location: A Bayesian hierarchical spatial model. Biometrics, early view on line 2009 Feb 4.
2. Yankeelov TE, Planey C, Welch EB, Xu L, Chakravarthy B, Getenby CJ, Freehardt D, mayer I, Meszeoly I, Kelley M, Powell JM, Gore JC, Temporal sampling requirements for reference region modeling of DCE-MRI data in human breast cancer. Journal of Magnetic Resonance Imaging, (accepted 2009 April)
C. Research Support
Ongoing Research Support
1UL1 RR024975-03 Bernard (PI) 06/01/09 – 05/31/10
NCRR
The Vanderbilt Institute for Clinical and Translational Research (VICTR) UL1
The goal of the Biostatistics and Ethics Core is to provide advanced biostatistical analyses in support of the
Vanderbilt Institute for Clinical and Translational Research
Role: Biostatistician
5U24 CA126588-0002 Gore (PI) 03/14/09 – 02/28/10
NCI
South-Eastern Center for Imaging Animal Models of Cancer
To support a new Small Animal Imaging Resource (SAIR) at Vanderbilt University, dedicated to providing
scientific and technical resources and support for non-invasive imaging of small animal models of cancer in
vivo
Role: Biostatistician
1R01 NS055822-01A2 Morgan (PI) 07/01/08– 06/30/09
NINOS
Temporal Clustering Analysis for Detection of Irregular Transient fMRI Activation
The overall goal of this project is to further develop and evaluate a novel, non-invasive imaging and analysis
method for all the detection and localization of transient, repeated, but irregular changes in brain activity using
functional Magnetic Resonance Imaging (fMRI)
Role: Biostatistician
Completed Research
NIH P01 CA 087684 09/01/03-12/30/07
Automatic 3D Registration for Enhanced Cancer Management
This program project is a pre-clinical test of the role of 3D registration techniques to assist detection and interpretation of lesion changes between interval exams, define organs automatically for radiation therapy treatment planning, apply diagnostic pre-surgical planning fMRI studies in patients with lesion-induced hyperkinesis via 3D slice-based motion correction, apply registered CT side information to improve PET sensitivity and specificity for small lung neoplasms.
Role: Student Research Assistant
PHS 398/2590 (Rev. 11/07) Page 2 Biographical Sketch Format Page