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Lin, Jen-Kun
Publication List : Jen-Kun Lin, Professor
Institute of Biochemistry
College of Medicine
National Taiwan University
Total refereed papers: 359 ( As of January 12, 2009)
I. Papers published in International
Journals: 238 (pp. 1-24).
II. Papers published in National
Journals: 121 (pp. 25-34).
Total meeting papers: 187
III. Abstracts (pp 35-54).
Total books (11):
IV. Names of books (p.55)
Among referred papers,259 papers have been cited(some of them were highly cited). The total times cited were over 7000 (Please see Web of Science, Citation Report, AU=(LIN JK).Date: Feb. 7, 2009)
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Lin, Jen-Kun
PUBLICATIONS
I. Refereed Journals (Papers published in International Journals):
* : indicates corresponding author.
1. Lin, Jen-Kun, Miller, J. A*. and Miller, E. C. Studies on the structures of polar dyes from liver proteins of rats fed N-methyl-4-aminoazobenzene I. Retention of the methyl group. Biochem. Biophys. Res. Commun. 28: 1040-1046, 1967.
2. Lin, Jen-Kun, Miller, J. A.* and Miller, E. C. Studies on structures of polar dyes derived from the liver proteins of rats fed N-methyl-4-aminoazobenzene II. Identity of synthetic 3-( homocystein-S-yl )-N-methyl-4-aminoazobenzene with the major polar dyes p2b. Biochemistry 7: 1889-1895, 1968.
3. Lin, Jen-Kun, Miller, J. A*. and Miller, E. C. Studies on the structures of polar dyes derived from the liver proteins of rats fed N-methyl-4-aminoazobenzene III. Tyrosine and homocysteine sulfoxide polar dyes. Biochemistry : 1573-1582, 1969.
4. Lin, Jen-Kun and Miller, J. A*. Synthesis of the hepatocarcinogen, N-methyl-4-aminoazobenzene with tritium in the prime ring. J. Labelled Compounds 5: 259-260, 1969.
5. Lin, Jen-Kun. Characterization of the structures of polar dyes derived from the carcinogen N-methyl-4-aminoazobenzene. Ph. D. Thesis, University of Wisconsin, 1969, Madison, Wisconsin, USA.
6. Lin, Jen-Kun*, Hsu, Su-Ming and Wu, Yen-Hwa. Methemoglobin induced by carcinogenic aminoazo dyes in rats. Biochem. Pharmacol. 21: 2147-2150, 1972.
7. Lin, Jen-Kun * and Wu, Yen-Hwa. Studies on the mechanism of methemoglobin formation induced by aminoazo compounds. Biochem. Pharmacol. 22: 1883-1891, 1972.
8. Lin, Jen-Kun* and Fok, K. F. Chemically induced binding of the hepatocarcinogen N-methyl-4-minoazobenzene to nucleic acids in vitro. Cancer Res. 33: 529-535, 1973.
9. Lin, Jen-Kun* and Wu, Jeng-Ren. Synthesis, toxicities and carcinogenicities of carcinogenic bifunctional aminoazo dyes. Cancer Res. 34: 2274-2282, 1974.
10. Lin, Jen-Kun* and Chang, J. Y. Chromophoric labeling of amino acids with 4-dimethylaminoazobenzene-4'-sulfonyl chloride. Anal. Chem. 47:1634-1638, 1975.
11. Lin, Jen-Kun, Schamall, B., Sharpe, I. D. Mura, I. Miller, J. A*. and Miller, E. C. N-Substitution of carbon 8 in guanosine and deoxyguanosine by the carcinogen N-benzoyloxy-N-methyl-4-aminoazobenzene in vitro. Cancer Res. 35: 832-843, 1975.
12. Lin, Jen-Kun, Miller, J. A*. and Miller, E. C. Structures of hepatic nucleic acid-bound dyes in rats in rats given the carcinogen N-methyl-4-aminoazobenzene. Cancer Res. 35: 844-850, 1975.
13. Lin, Jen-Kun, Miller, J. A.* and miller, E. C. Studies on the characterization of the hepatic nucleic-bound forms of aflatoxin B1 in the rats. In: Animal, Plant and microbial toxins ( Proceedings of 5th international symposium on toxicology, San pergamon Press, Oxford and New York, 1978.
14. Lin, Jen-Kun, Miller, J. A*. and Miller , E. C. 2,3-Dihydro-2-( guan-7-yl )-3-hydroxy-aflatoxin B1-DNA or rRNA adducts formed in hepatic microsome-mediated reactions and in rat liver in vivo.
Cancer Res. 37:4430-4438, 1977.
15. Lin, Jen-Kun, Kennan,K.A., Miller, E. C. and Miller J. A*. Reduced nicotinamide adenine Dinucleotide phosphate-dependent formation of 2,3-dihydro 2,3-dihydroxy aflatoxin B1 from aflatoxin B1 by hepatic Microsomes. Cancer Res. 38: 2424-2428, 1978.
16. Lin, Jen-Kun* and Lai, Chen-Ching. High performance liquid chromatographic determination of naturally occurring amines with dabsyl chloride. Anal. Chem. 52: 630-635, 1980.
17. Carruthers, Chris*, Baumler, Alverna and Lin, Jen-Kun. Detection by antihapten antibodies of liver-bound compounds related to azocarcinogens or their metabolites. Oncology 36: 211-215,1979.
18. Lin, Jen-Kun* and Wang, C. H. Determination of urinary amino acids by liquid chromatography with dabsyl chloride. Clin. Chem. 26: 543-547, 1980.
19. Lin, Jen-Kun* and Yen, Jong-Young. Changes in the nitrate and nitrite contents of fresh vegetables during cultivation and post-harvest storage. Fd. Cosmet. Toxicol. 18: 597-603. 1980.
20. Lin, Jen-Kun* and Lai, C. C. Effect of lactobacillus antacids and antibiotics on the levels of nitrite in the gastrointestinal tracts of rats fed sodium nitrate. Fd. Chem. Toxicol. 20: 197-204, 1982.
21. Lin, Jen-Kun* and Lai, Cheng-Ching. Chromophoric determination of puterscine, spermidine and spermine with dabsyl chloride by HPLC and TLC. J. Chromatogr. 227: 369-377,1982.
22. Liaw, K. Y*., Wei, T. C., Hsu, S. C. and Lin, Jen-Kun. Muscle energy metabolism in traumatic, septic and critically ill patients-- A percutaneous muscle biopsy study. Southeast Asian J. Surg. 5 ( 2 ): 107-113, 1982.
23. Lin, Jen-Kun, Lee, Y. J. and Chang, H. W. High contents of methylamine and dimethylamine in squid and octopus and their implication in the etiology of tumors. Fd. Chem. Toxicol. 21: 143-149, 1983.
24. Lin, Jen-Kun* and Chang, H. W. Naturally occurring amines in seafoods and their implication of endogenous carcinogenic nitrosamines. Developments in the science and practice of toxicology Vol. 11: 379-382, 1983. A. W. Hayes, et al. ed. Elseiver Science Publishers, B. V.
25. Lin, Jen-Kun*. Dabsyl amino acids. In: CRC Handbook of HPLC for the Separation of Amino Acids, Peptides and Proteins, Vol. I., W.S. Hancocked., CRC Press, Inc., Boca Raton, Florida, PP. 359-366, 1984.
26. Chang, W. M. and Lin, Jen-Kun*. Transformation of zearalenone and zearalenol by rat erythrocytes. Fd. Chem. Toxicol. 22 ( 11 ): 887-891, 1984.
27. Lin, Jen-Kun*, Chang, H. W. and Lin-Shiau, Shoei-Yn. Abundance of dimethylamine in seafoods: Possible implication in the incidence of human cancer. Nutr. Cancer 6: 148-159, 1984.
28. Lin, Jen-Kun*, Yen, J. Y., Chang, H. W. and Lin-Shiau, Shoei-Yn. N-Nitrosophenacetin: Its synthesis, Characterization, mutagenicity and teratogenicity. J. Natl. Cancer Inst. 72 ( 4 ): 863-869, 1984.
29. Liaw, K. Y*., Wei, T. C., Hsu, S. C. and Lin, Jen-Kun. Effect of severe injury and critical illness on high energy phosphates in human liver and muscle. J. Trauma 25 ( 7 ): 628-633, 1985.
30. Chang, W. M., Lin, Jen-Kun*, and Hsiung, K. P. Immobilization of rat erythrocytes for aflatoxicol production. Appl. Microbial. Biotechnol. 21: 361-364, 1985.
31. Lin, Jen-Kun* and Hurng, D. C. Thermal conversion of trimethylamine-N-oxide to trimethylamine and dimethylamine in squids. Fd. Chem. Toxicol. 23 ( 6 ): 579-583, 1985
32. Chang, W. M., Lin, Jen-Kun*, Wu, K. C., and Hsiung, K. P. In vitro interconversion of aflatoxin B1 and aflatoxicol by rat erythrocytes. Biochem. Pharmacol. 34 ( 14 ): 2566-2569, 1985.
33. Lin, Jen-Kun* and Wang, Chau-Jong. Reversible hepatic toxic effect of crocin dyes in rats. Korean J. Pharmacognosy, 16 ( 4 ): 227-232, 1985.
34. Lin, Jen-Kun* and Wang, Chau-Jong. Protective effects of crocin dyes on the acute hepatic damage induced by aflatoxin B1 and dimethylnitrosamine. Carcinogenesis 7 ( 4 ): 595-599, 1986.
35. Lin, Jen-Kun *and Horng, Tzyy-Show. The toxicity and mutagenicity of N-nitrosocompounds in Sarcina lutea and Salmonella typhimurium. Toxicity Assessment 1 ( 3 ): 339-355, 1986.
36. Lin, Jen-Kun* and Wu, Shan-Shou. Synthesis of dabsylhydrazine and its use in the chromophoric determination of monosaccharides by thin layer and high performance liquid chromatography. Anal. Chem. 59: 1320-1326, 1987.
37. Lin, Jen-Kun* and Kuo, Ming-Liang. Characterization of the adducts derived from the reactions of mutagenic N-nitrosophenacetin with tryptophan, cysteine, and glutathione. Asia-Pacific Communication in Biochemistry 1 ( 3 ): 107-115, 1987.
38. Lin, Jen-Kun* and Kuo, Ming-Liang. N-Nitroso-N-2-fluorenylamide: a New direct-acting mutagen and teratogen. Mutation Res. 201: 117-126, 1988.
39. Li, Shuan-Yow, Tsai, Chin-Chu, Chou, Ming-Yung and Lin, Jen-Kun*. A cytogenetic study of mentally retarded school children in Taiwan with special rference to the fragile X chromosome. Human Genetics 79: 292-296, 1988.
40. Lin, Jen-Kun*. Kuo, Ming-Liang, and Hsu, Lee-Way. Studies on the genotoxicity of dipyridyl and biphenyl derivatives using Salmonella Typhimurium. Toxicity Assessment 3: 161-171, 1988.
41. Kuo, Ming-Liang and Lin, Jen-Kun*. The relationship between DNA damage and mutation frequency in mammalian cell lines treated with N-nitroso-N-2-Fluorenylacetamide. Mutation Res. 212: 231-239, 1989.
42. Lin, Jen-Kun* and Hurng, Dong-Chirr. Potentiation of ferrous sulfate and ascorbate on the microbial transformation of endogenous trimethylamine-N-oxide to trimethylamine and dimethylamine in squid extract. Fd. Chem. Toxicol. 27 ( 9 ): 613-618, 1989.
43. Wang, Chau-Jong, Chou, Ming-Yun and Lin, Jen-Kun*. Inhibition of growth and development of the transplantable C-6 glioma cell inoculated in rat by retinoids and carotenoids. Cancer Letters, 48: 135-142, 1989.
44. Lin, Jen-Kun* and Kuo, Ming-Liang. Induction ouabain-resistance mutation and cycle-dependent transformation of C3H 10T 1/2 cells by N-nitroso-N-2-Fluorenylacetamide. Mutation Res. 230: 35-43, 1990.
45. Lin, Jen-Kun. Nitrosamines as potential environmental carcinogens in man. Clin. Biochem. 23: 67-71, 1990.
46. Li, Shuan-Yow and Lin, Jen-Kun*. Differential bleomycin susceptibility in cultured lymphocytes and fragile X patients and normal individuals. Human. Genet. 85: 261-271, 1990.
47. Li, Shuan-Yow and Lin, Jen-Kun*. Sequential monitoring of cytogenic damage in rat lymphocytes following in vivo exposure to aflatoxin B1 and N-nitrosophenacetin. Mutation Res., 242: 219-224, 1990.
48. Wang, Chau-Jong, Wang, Shao-win, Shiah, Her-Shyong and Lin, Jen-Kun*. Effect of ethanol on hepatotoxicity and hepatic DNA-binding of aflatoxin B1 in rats. Biochem. Pharmacol. 40 ( 4 ): 715-721, 1990.
49. Wang, Chau-Jong, Shiah, H-S. and Lin, Jen-Kun*. Modulatory effect of crocetin on aflatoxin B1 cytotoxicity and DNA-adduct formation in C3H 10T 1/2 fibroblast cell. Cancer letters, 56: 1-10, 1991.
50. Wang, Chau-Jong, Shiow, Song-Jui and Lin, Jen-Kun*. Effects of crocetin on the hepatotoxicity and hepatic DNA-binding of aflatoxin B1 in rats. Carcinogenesis 12 ( 3 ): 459-462, 1991.
51. Huang, Tsu-Sing, Lee, Sheng-Chung and Lin, Jen-Kun*. Supression of the c-Jun/AP-1 activation by an inhibitor of tumor formation in mouse fibroblast cells. Proc. Natl. Acad.Sci., USA, 88: 5292-5296, 1991
52. Wang, Chau-Jong, Wang, S. W. and Lin, Jen-Kun*. Suppressive effect of geniposide on the hepatotoxicity and hepatic DNA binding of aflatoxin B1 in rats. Cancer Letters, 60: 95-102, 1991.
53. Wang, Chau-Jong, Hsu, Jeng-Dong and Lin, Jen-Kun*. Supression of aflatoxin B1-induced hepatotoxic lesions by crocetin ( a natural carotenoid ). Carcinogenesis, 12 ( 10 ): 1807-1810, 1991.
54. Ou, Yueh-Hsing and Lin, Jen-Kun.* Biotransformation of butachlor through mercapturic acid pathway in rat tissue homogenates.J. Toxicol. Environ. Health 35: 19-30, 1992.
55. Lin, Jen-Kun* and Tseng, Shun-Fen. Chromosomal aberrations and sister-chromatid exchanges induced by N-nitroso-N-2-Fluorenylacetamide and their modifications by arsenite and selenite in Chinese hamster ovary cells. Mutation Res. 265: 203-210, 1992.
56. Lin,Jen-Kun*, Cheng, Jiin-Tsuey and Lin-Shiau Shoei-Yn. Enhancement of the mutagenicity of IQ and MeIQ by nitrite in the Salmonella system. Mutation Res. 278: 277-287, 1992.
57. Lin, Jen-Kun* and Lee, Shern-Fwu. Enhancement of the mutagenicity of polyphenols by chlorination and nitrosation in Salmonella typhimurium. Mutation Res. 269: 217-224, 1992.
58. Kuo, Min-Liang, Lee, Kuen-Chen and Lin, Jen-Kun.* Genotoxicities of nitropyrenes and their modulation by apigenin, tannic acid, ellagic acid and indole-3-carbinol in the Salmonella and CHO systems. Mutation Res. 270: 87-95, 1992.
59. Lin, Jen-Kun *and Ho, Yuan-Soon. Hepatotoxicity and hepatocarcinogenicity in rats fed squid with or without exogenous nitrite. Food and Chem. Toxicol. 30 ( 8 ): 695-702, 1992.
60. Wang, Chau-Jong,* Tseng, Tsui-Hwa and Lin, Jen-Kun. Penta-acetyl geniposide: isolation, identification and primary effect on C6 Glioma cells in vitro. Anticancer Res. 12: 911-916, 1992.
61. Wu, Wen-Sheng, Lin, Jen-kun, and Wu, Felicia Y.-H*. Differential induction of c-fos and c-jun proto-oncogenes and AP-1 activity by tumor promoter 12-o-tetraadecanoyl-phorbol 13-acetate in cells at different stages of tumor promotion in vitro. Oncogene 7 : 2287-2294, 1992.
62. Wang, Jin-Mei, Lin-Shiau, Shoei-Yn and Lin, Jen-Kun*. Relaxation of rat thorcic aorta by N-nitroso compounds and nitroprusside and their modifications of nucleic acid bases through release of nitric oxide. Biochem. Pharmacol. 45: 819-825, 1993.
63. Shih, Cheng-An and Lin, Jen-Kun*. Inhibition of 8-hydroxydeoxyguanosine formation by curcumin in mouse fibroblast cells. Carcinogenesis 14 ( 4 ), 709-712, 1993.
64. Liu, Jer-Yuh, Lin, Su-Ju and Lin, Jen-Kun*. Inhibitory effects of curcumin on protein kinase C activity induced by 12-O-tetradecanoyl-phorbol-13-acetate in NIH 3T3 cells. Carcinogenesis 14 ( 5 ), 857-861, 1993.
65. Wang, C. J*., Chu, C.Y., Tseng, T.H. and Lin J.K. Pentaacetylgeniposide inhibits the growth and development of C-6 glioma cells in rats. Cancer letters. 70: 113-118, 1993.
66. Kuo, M.L. and Lin, J.K*. The genotoxicity of the waste water discharged from paraquet manufacturing and its pyridyl components. Mutation Res. 300: 223-229, 1993.
67. Kuo, M.L. Wu, W.S., Lee, K.C. and Lin, J.K*. Effects of tannic acid on TPA induced protein kinase C activation in NIH 3T3 cells. Biochem Pharmacol. 46 (8): 1327-1332, 1993.
68. Lee, C. C., Lin, H. K. and Lin, J. K*. A reverse mutagenicity assay for alkylating agents based on a point mutation in the beta-lactamase gene at the active site serine codon Mutagenesis 9 (5): 401-405, 1994.
69. Lin, Jen-Kun *and Shih, Cheng-An. Inhibitory effect of curcumin on xanthine dehydrogenase/oxidase induced by phorbol-12 myristate-13-acetate in NIH3T3 cells. Carcinogenesis 15 (8): 1717-1721, 1994.
70. Ho, Yuan-Soon and Lin, Jen-Kun*. N-Nitroso-2-acetylaminofluorene : A direct-acting carcinogen inducing hepatocellular carcinoma in Sprague-Dawley rats. Jpn. J. Cancer Res., 85,, 794-800, 1994.
71. Lin, Jen-Kun* and Ho, Yuan-Soon. Hepatotoxic action of dietary amines. Toxicology and Ecotoxicology News, 1(3): 82-87, 1994.
72. Wang, Jin-Mei, Chow, Song-Nan and Lin, Jen-Kun*. Oxidation of LDL by nitric oxide and its modification by superoxides in macrophage and cell-free systems. FEBS Letters 342 : 171-175, 1994.
73. Wang, Chau-Jong*, Lin, Y. L. and Lin, Jen-Kun. Mutagenicity and cytotoxicity of nitropyrrole compounds derived from the reaction of 2-acetyl-pyrrole with nitrite.Food & Chem. Toxicol. 32 (9): 839-844, 1994.
74. Kuo, Min-Liang*, Lin, Jen-Kun, Tze-Sing Huang and Nae-Cherng Yang. Reversion of the transformed phenotypes of v-H-ras NIH 3T3 cells by flavonoids through attenuating the content of phosphotyrosine. Cancer Lett. 87: 91-97, 1994.
75. Wang, Chau-Jong*, Lee, Miao-Jane, Chang, Ming-Cheng and Lin, Jen-Kun. Inhibition of tumor promotion in benzo(a)pyrene-initiated CD-1 mouse skin by crocetin. Carcinogenesis 16(2): 187-191, 1995.