Curriculum Vitae
Dr Noor Mohammed
MBChB, MRCP, DGM, MD, CCST
Application for Consultant Interventional Cardiologist
Personal detailsFull name / Noor U H Mohammed
Permanent address / 3 Jellicoe road
Leicester
LE5 4FP
Date of Birth / 12/12/1978
Email /
Nationality / British
GMC number / 6041854
Marital Status / Married
Education
1988 - 1995 / All Saints High School, Hyderabad-India
5 A's at A level in mathematics, physics & chemistry, 7 A* GCSEs
1996 - 2002 / University of Health Sciences-Hyderabad, India
Qualifications
Aug 2015 / CCT General and Intervention cardiology
July 2015
/ MD awarded
University of Leicester
July 2013 / Knowledge based assessment ESC exam
Dec 2008
April 2005
Aug 2002 / Diploma in Geriatric medicine, RCP, London
MRCP, RCP, London
MBChB, University of Health Sciences, India
Advanced life support Certification-2007, 2011 and 2014
Personal details
Employment History
West Midlands SpR training rotation
Aug 2015 (Current post)
Consultant Interventional Cardiologist
New Cross Hospital, Wolverhampton, busiest tertiary centre in West Midlands-Coronary intervention, Structural programme, 1600 PCI procedures annually
(1:8 primary PCI on call, 1 Clinic, 4 PCI sessions weekly, Registrar teaching)
Sep 2013-Aug 2014
Interventional Fellow- ST6 and ST7
University Hospital of Coventry and Warwickshire- 1200PCI procedures/year
New Cross Hospital, Wolverhampton-1600 PCI/year, structural programme
Sep 2012- Aug 2013
GUCH/Electrophysiology/Imaging module-ST5 (Dr Peter Glennon)
University Hospital of Coventry and Warwickshire
(1:9 primary PCI on call, 2 Clinics, 2 cathlab, 2 echo session)
GUCH clinics at UHB (Dr Thorne); pregnancy clinics at UHCW (Dr Adamson)
Aug 2011-Sep 2012
General Cardiology and Internal Medicine - ST4 (Dr Richard Watkin) Good Hope Hospital NHS Trust
(1:7 GIM on call, 2 clinics, 2 PCI sessions at Heartlands Hospital)
Aug 2010-Sep 2011
General and Interventional Cardiology-ST3 (Dr Bethan Freestone/Dr Mike Pitt)
Heartlands Hospital NHS trust
(1:5 primary PCI on call, 3 PCI and 1 diagnostic catheter session, 1 device sessions alternate week at Solihull Hospital, 2 clinics)
May 2009-July 2010
LAT SpR in Cardiology
Glenfield Hospital-East Midlands rotation (Dr Jan Kovac / Dr Ian Loke)
(1:10 primary PCI on call, 2 diagnostic and 2 device, 2 clinics, 2 echo sessions)
April 2007- March 2009
Research fellow- Cardiovascular Sciences, University of Leicester (Prof L Ng)
Aug 2005- March 2007
Trust Registrar-Department of Cardiology, South Warwickshire Hospital
(1:7 GIM on call, 2 catheter labs, 4 General cardiology clinics)
MD Research: Novel peptides in acute heart failure
April 2007 to May 2009: Research Fellow
Department of Cardiovascular Sciences
University of Leicester
Supervisors: Professor L Ng/ Iain Squire MD award (June 2015)
I have completed a 2-year research period evaluating the prognostic role of novel biomarkers in 400 hospitalised patients presenting with acute heart failure to our institution. We investigated the role of matrix metalloproteinase subtypes 2, 3, 9 and natural inhibitors (TIMP 1-4) relationship with echo derived markers of LV dysfunction and adverse remodelling. (Funding: University of Leicester grant)
Methods: Plasma MMP and TIMP levels were measured at admission and at discharge. LV function (LVEF) was assessed by echocardiography pre-discharge and combined primary clinical endpoint of death or heart failure readmission was assessed at 365 days.
Results: MMP 3 levels are high in patients reaching the primary end point and peak prior to discharge. It was higher in males (p<0.001) and hypertensive (p<0.01) and was associated with past history of heart failure (p=0.01) and chronic renal failure (p<0.001). It had direct correlation with age (p<0.001) and inversely correlated with eGFR (p<0.001) and heart rate (p<0.008). It was higher in subjects with LVEF <40% (p=0.017) compared to those with EF >40%.In the 173 patients reaching the endpoint, MMP-3 was higher with a median log₁₀ value of 26.07ng/ml (16.46 to 36.38) vs. 17.68ng/ml (11.42 to 31.33), p<0.001.In addition MMP 3 was high in 108 patients who died[29.66ng/ml (19.48 to 41.12) vs. 18.9ng/ml (11.78 to 30.7) p<0.001] as compared to those who did not.
In comparison, Discharge MMP 9 levels had negative correlation with patients age (p=0.003) and had positive relationship with LV end systolic volume. Levels were low in patients who reached primary combined end point (p<0.001) and death (p=0.007) alone when compared to those who did not. No significant relationship was demonstrated with MMP 2 and TIMP (natural inhibitors of MMP) with the primary combined outcome or death.
Conclusion: Raised MMP-3 and low MMP-9 levels are associated with worse prognosis after admission with acute HF, and may be indicators of adverse LV remodelling.
The findings had been presented at National and International meetings (BCS, ESC and European HF Congress meetings)
Publications and Abstracts
Ventricular tachycardia following aortic valve replacement (case report)
Noor Mohammed, Dandekar U, Osman F
Heart, Jan 2015 heartjnl-2015-306971
Spinal Hematoma following dual antiplatelet therapy in acute coronary syndrome
Noor Mohammed, Shahid M, Ed Hoey (case report)
Quantitative imaging of medicine and surgery,10.3978/j.issn.2223-4292.2015
Comparison of complete versus incomplete stent frame expansion following TAVI implantation with Medtronic core valve bio prosthesis. (Research article)
Jilahawi H, Chin D, Jeilan M, Mohammed N, Bence J, Logtens E, Kovac J.
(American Journal of Cardiology Jun 15 2011; 107(12):1830-7)
Activation of a novel natriuretic endocrine system in human with heart failure
Narayan H, Mohammed N, Quinn PA, Squire IB, Davies JE, Ng LL.
Clin Sci (Lond). 2010 Mar; 118 (5):367-74 (Research article)
MMP2 predicts mortality in patients with Acute Coronary Syndromes
Onkar Dillon, Noor Mohammed, Iain B. Squire, Joan E. Davies, Leong L. Ng
Clinical Science (Lon).2009 Nov, 118(4):249-57 (Research article)
Left ventricular non-compaction: clinical features and CMR imaging
Zaheer Yousef, S Chalil, H Sandman, Noor Mohammed, Paul Foley, F Leyva
(BMC Cardiovascular Disorders) 2009 Aug 9; 9:37 (Research article)
Electrical and Mechanical Alternans associated with Cardiac tamponade
Jeilan M, Kundu S, Mohammed N, Loke I (case report)
BMJ case reports 2010, 10.1136/bcr.06.2008.0100
Presented abstracts
Valve in valve in valve following tissue AVR failure
Mohammed N, Khogali S (oral presentation) London PCR valves, Berlin 2015
Dual access stenting in cardiogenic shock and STEMI
Mohammed N, Khogali S (oral presentation) EuroPCR 2015
Differential prognostication of MMP in HFrEF and HFpEF
Mohammed N, Narayan H, Squire IB, Ng LL- BCS, Manchester 2015
MMP-3 & MMP-9: novel peptides indicator of LV remodelling & mortality in AHF
Mohammed N, Squire IB, Ng LL- Rapid Fire (oral presentation) ESC-2014
Mean E/e` predicts one year mortality in acute heart failure
Mohammed N, Squire IB, Ng LL-European HF Congress, Athens 2014
Stromelysin (MMP-3) is a predictor of all-cause mortality in AHF
Mohammed N, Narayan H, Squire IB, Ng LL- BCS, Manchester 2014
Spontaneous LAD dissection in Ant phospholipid antibody syndrome-case report
Mohammed N, Richard Watkins, John Milles
West Midlands Endocrine Club and West Midlands Physicians Association meeting (shortlisted for Stephen Whittaker prize) 2011
Educational meetings and courses
2015
Left main stem management, Glenfield Hospital
PCI complications, Derby Royal Infirmary (Best case-runner up prize)
BCIS Intervention fellows’ course, Stoke on Trent
IVUS and OCT Imaging, Manchester
EuroPCR, Paris (abstract presentation)
BCS Annual conference (abstract presentation)
2014
BSH training day, Glasgow
Impella training course, Birmingham
Bifurcation Lesion treatment, BLT-Birmingham
BCIS Intervention fellow course-Leeds
Derby PCI Complications course
ESC Heart failure Congress, Athens (Abstract presentation)
BCS Annual conference, Manchester (Abstract presentation)
2013
PCI Complications, Derby
GUCH and pregnancy in heart disease, Leeds
Advance Imaging, Royal Society of medicine, London
CTO 10, Glenfield Hospital
2012
CTO 9, Glenfield Hospital
West Midlands Physicians meeting (presented case report for Stephen Whitaker prize) City Hospital, Birmingham
Midlands Endocrine Club meeting, Birmingham Motorcycle Museum
Imperial Valve course, Kings College, London
Nuclear Imaging, City Hospital, Birmingham
National training day-Nuclear medicine, Royal College of physicians, London
2011
European Interventional fellows course, London
Advanced Imaging in Cardiac Source of Embolism, RSM
Advanced Life Support, Heartlands Hospital
Cardiac MRI, QEH (June 2011)-Level 1 Accreditation
2010
Leicester Live Device Course (presenter)-Glenfield
PCI Complications-Worcester Royal Infirmary
BSE Annual Conference, Bournemouth (3 days)
Conferences attended
EuroPCR- oral presentation, 2015
British Cardiac Society Annual conference- Abstract presentation 2014 and 2015
Faculty 2013
Delegate 2010-2012
British Society of Heart Failure Annual conference- 2013, 2014
European Heart failure Congress- Athens-poster presentation, 2014
ESC Congress, Barcelona- Oral paper (10min) Sep 2014
BCIS– Advanced angioplasty meeting, London - 2013-2015
British Society of Echocardiography Annual conference- 2008, 2010
Prizes and Achievements
1997-2001 Distinction in pathology, medical school
Dr.Sita Devi Gold Medal (Highest Grades- Final MBChB)
Runner up in Regional Paediatric quiz
2015 Derby PCI Complication, Runner up prize
Audits
Out of Hospital Cardiac arrest in context of STEMI (in progress) New Cross Hospital NHS trust
Percutaneous coronary intervention in the octogenarian population at Walsgrave Hospital in last 3 years (2013) - data presented at West Midlands Intervention meeting held in Birmingham.
Primary PCI timings at University Hospital of Coventry and Warwickshire (Audit cycle completed 2013) -Data presented at monthly QIPPS meeting.
Audit into Cardiogenic shock and IABP usage at Heart of England NHS trust (2011) - Recommended increases balloon pump use in cardiogenic shock. I had presented the data at departmental and West Midlands Intervention meeting in February 2012.
Internal cardioversion in persistent Atrial Fibrillation (2010): recommendation to offer the service to high BMI patients -Heartlands Hospital.
Management and Investigations of Heart Failure Patients (2009) – recommended increased use of ACEI and BB and Heart failure nurse led service-Glenfield
Outcome of CT Brain in suspected cases of Meningitis (2003)-CT scan delays antibiotic administration and lumbar puncture in the absence of focal neurological signs. The findings were presented at the West Midlands Radiology Spring meeting
Teaching
I am passionate about my contribution to the development of medical students, nurses, cardiac physiologists and junior doctors. I am sensitive to students needs and enjoy breaking complex problems into simple parts, providing detailed feedback and encouraging students to help each other and ask questions. I have also attended Teach the trainer course. I have organised and participated in the clinical teaching of pre and postgraduate students and doctors, including organising teaching rotas for PACES and final exams. I have attended structured “teach the trainer” course at University Hospitals of Leicester NHS trust.
I supervise junior registrars learning to undertake coronary angiography. Informal bedside teaching is ingrained into my everyday work and I teach students and junior doctors on a daily basis as well as at the bedside in small groups. I have given educational presentations at medical grand rounds, departmental seminars and regional meetings.
I have given presentations at local coronary support group to help educate post infarction patients.
I have covered following topics at various time periods during my rotation
· Pregnancy and Arrhythmias – Electrophysiology meeting, Glenfield Hospital
· Regular educational meetings for GP’s, Medical Registrars (ACS, AF, HTN)
· House Officers, SHO’S teaching – How to read ECG August 2004 &2007
· Echo Journal Club meeting-Glenfield Hospital
· Leicester Live Device Course 2009 (presenter)
· Post-partum Dilated Cardiomyopathy, Journal Club 2010, Heartlands Hospital
· Forgotten Ventricle (RV infarction and complications)-Journal Club 2010, Heartlands Hospital
· Organised cardiology hot case meeting 2011-Good Hope Hospital
· Spontaneous coronary dissection 2012- Intervention meeting, UHCW
· Pressure wire study-FAME II study 2013- Intervention meeting, UHCW
· Diagnosis and Management dilemma in Infective Endocarditis, Grand Round 2013, UHCW (audience of 250 Hospital medical professionals)
Management and Leadership skills
As a senior registrar I have coordinated a group of 12 registrars and acted as a contact point for management staff and consultants. This involved organisation of rotas for clinical service provision incorporating leave organisation, teaching provision and ensuring seamless day to day cardiology service delivery in and out of hours and I attained invaluable exposure to how senior managers operate and the pressures of providing clinical excellence within financial and political limits. I have attended Medical Leadership and Management course at Oxford to help me understand the NHS management issues and lean work.
Recently I had organised and lectured at West Midlands` deanery cardiothoracic surgical training day held at UHCW, Coventry. I took the initiative to collaborate with surgeons in running a wet lab session on human cadaveric hearts for cardiac anatomy demonstration, which was a unique concept trialled for the first time in the deanery. I had received good feedback on both organisational and teaching skills. I attend monthly Clinical Governance meetings in addition to active participation in biweekly cardiothoracic Multidisciplinary meetings.
I was a part of Web casting team at last year BCS Annual conference. I am full ECDL certified and have working knowledge of SPSS, statistical software.
Clinical training
My training in interventional cardiology started when I joined West Midlands SpR training scheme. The job involved attachments to busy firms with a high intervention throughput. During this period I have gained confidence in managing and prioritising routine and emergency PCI lists as well as assessing patients before, during and after coronary intervention. This has included complex cases (three vessel, left main stem, chronic total occlusion) and exposure to intra-vascular ultrasound, pressure wire measurements and rotational atherectomy.
In the last 24 months I have been involved in 1200 intervention procedures of which 850 have been as first operator. I have gained invaluable experience in intervention strategy, equipment selection, lesion assessment and hand eye co-ordination. In addition I have completed core training in EP, Imaging and ACHD.
I am clinical firm in dealing with various acute medical and cardiac emergencies (SHO medical rotation and GIM SpR on calls).
Diagnostic angiography: 3500 cases (250 with right heart)
PCI: 1100 procedures (850 1st operator)
(80% Radial and 30% Elective)
o 175 Primary PCI
o 120 FFR, 43 IVUS, 12 OCT
o 25 rotational atherectomy
o 10 Left main (protected and unprotected)
o 20 Chronic total occlusion (antegrade)
o 4 TAVI, 6 Mitral valvuloplasty, 10 PFO (2nd operator)
o 4 Renal denervation
o 20 pericardiocentesis
o 30 IABP
TTE: Full Adult BSE transthoracic accreditation (>800 scans)
TOE: Full European TOE Accreditation awarded