Supplemental Table 1 Diagnostic criteria of asthma in the reports included in the meta-analysis

Author / Diagnostic criteria of asthma (Ref)
Jie et al.
2011 / The NIH Guidelines for the Diagnosis and Management of Asthma (Expert Panel Report 2007) or The GINA (Global Initiative for Asthma) Guidelines (http://www.ginasthma.org/) [1]
Qu et al. 2011 / Criteria established by the Chinese Society of Respiratory Diseases [2]
Bijanzadeh
et al. 2010 / The GINA guidelines (http://www.ginasthma.org/) [1]
Blakey et al. 2009 / Parental interviews in childhood, questionnaires in adulthood [3]
Su et al.
2008 / The Criteria of Chinese Society of Allergology [4]
Hirota et al. 2006 / The criteria of the American Thoracic Society [5]
Lee et al. 2004 / The criteria of the American Thoracic Society [5]
Howard et al. 2003 / The criteria of the Collaborative Study on the Genetics of Asthma [6]

References

1. Jie Z, Hu Z, Bai C, Jin M ADAM33 gene polymorphisms associate with asthma susceptibility and severity in East China han population. J Asthma 48:979-985

2. Qu S, Sun D, Wang Y, Zhang C, Lv Y, Yao L Association of ADAM33 polymorphisms with childhood asthma in a northern Chinese population. Exp Mol Pathol 91:775-779

3. Blakey JD, Sayers I, Ring SM, Strachan DP, Hall IP (2009) Positionally cloned asthma susceptibility gene polymorphisms and disease risk in the British 1958 Birth Cohort. Thorax 64:381-387

4. Su D, Zhang X, Sui H, Lu F, Jin L, Zhang J (2008) Association of ADAM33 gene polymorphisms with adult allergic asthma and rhinitis in a Chinese Han population. BMC Med Genet 9:82

5. (1991) Guidelines for the diagnosis and management of asthma. National Heart, Lung, and Blood Institute. National Asthma Education Program. Expert Panel Report. J Allergy Clin Immunol 88:425-534

6. (1997) A genome-wide search for asthma susceptibility loci in ethnically diverse populations. The Collaborative Study on the Genetics of Asthma (CSGA). Nat Genet 15:389-392

SUPPLEMENTAL FIGURE LEGEND

Supplemental Figure 1. Regional LD plots of the T1 (rs2280091) (A), T2 (rs2280090) (B), and ST+7 (rs574174) (C) polymorphisms. Polymorphisms are plotted along with their proxies (based on the 1000 genome project) as a function of genomic location, annotated by recombination rate across the locus (light-blue line). On the y-axis, pairwise r2 values are provided for each proxy SNP using color codes.

Figure 1

A.

B.

C.