CURRICULUM VITAE

______

Signature

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Date

HARRY T. CHUGANI, M.D.

OFFICE ADDRESS:Children's Hospital of Michigan

Pediatric Neurology / PET Center

3901 Beaubien Blvd

Detroit, Michigan 48201-2196

(313) 993-2605(Office)

(313) 745-0955 (Fax)

(248) 932-5249(Home)

E-Mail:

DATE OF BIRTH:October 6, 1948

PLACE OF BIRTH:Hong Kong

CITIZENSHIP:United States

FACULTY PROFESSIONAL EXPERIENCE:

Los Angeles:

Assistant Professor, Departments of Neurology and Pediatrics, UCLA School of Medicine

July 1981 - June 1988

Associate Professor with Tenure (accelerated promotion), Departments of Neurology and Pediatrics, UCLA School of Medicine

July 1988 - July 1993

Consultant in Pediatric Neurology, Olive View Medical Center, Los Angeles

1981 - 1991

Faculty of the Brain Research Institute, UCLA

1987 – 1993

Instructor, Division of Nuclear Medicine and Biophysics, UCLA, 1990-1992

Associate Professor, Division of Nuclear Medicine and Biophysics, UCLA, 1992-1993

Detroit:

Professor, Departments of Pediatrics, Neurology and Radiology

Director, Positron Emission Tomography Center

Director, Pediatric Epilepsy Surgery Program

Children's Hospital of Michigan, Wayne State University

July 1993 – Present

Chief, Division of Pediatric Neurology, Children’s Hospital of Michigan

January 1999 – Present

Rosalie and Bruce Rosen Chair in Neurology, November 2002

Professor, Department of Pharmacology, September 2006 - present

SPECIALTY BOARD CERTIFICATION

Neurology: Diplomat, American Board of Psychiatry and Neurology (1982), with

Special Competency in Child Neurology

Pediatrics: American Board of Pediatrics (board-eligible).

Nuclear Medicine: Board-eligible - July 1992

SOCIETIES

1.Alpha Epsilon Delta

2.American Academy of Neurology

3.Child Neurology Society

4.Society for Neuroscience

5.International Child Neurology Association (Executive Board Member 2006 – present)

6.American Epilepsy Society

HONORS AND AWARDS

1.UCLA Pediatrics Faculty Scholar Award (1986-1987)

2.Young Investigator Award (1986-1987) - Association of Indian Neuroscientists

(USA)

3.Acknowledgment in the President's A Report to the Regents of the University

of California, March 21, 1986.

4.Best abstract: XIII International Symposium on Cerebral Blood Flow and

Metabolism. Montreal, June 1987.

5.Certificate of Merit: Scientific Exhibit Award. Radiological Society of North

American, Chicago, November-December, 1987.

6.Distinguished Scientist Award (1992): Crump Institute, UCLA

7.Killam Honorary Lecturer. Montreal Neurological Institute, McGill University, Montreal, May 1997.

8.Appeared before the United States Senate Subcommittee on Children and Families

as an invited expert to testify on research progress in child brain development.

Washington, D.C., June 1997

9.White House conference on Brain Development; invited by President and

Mrs. Clinton. Washington, D.C., April 1997, The White House.

10.Niilo Hallman Award for Outstanding Research in Pediatrics. Awarded by the

University of Helsinki. Helsinki, Finland. September 1997.

11.Milestone Award (MIRA) Mental Illness Research Association 1997 Recognition

for contribution to the understanding of autism.

12.Holroyd Award. Recognition award for a distinguished graduate in the health care

profession. La Salle University, Philadelphia, PA., April 1998.

  1. 1st Annual Sunny Days Award, Sesame Street Parent Magazine, June 1998.

14. Invited to become member of the Dana Alliance for Brain Initiatives, November

1998.

15.Robert Dow Lecture. Legacy Portland Hospitals. Portland, OR, December 1998.

16.Michigan Council for Maternal and Child Health’s Outstanding Achievement Award,

May 1999.

17.Named as one of the “top docs” in Michigan: Hour Magazine survey. October 2000.

18.Invited to become member of the Professional Advisory Committee of the Epilepsy Foundation of Michigan. October 2000.

19.Richmond Paine Lecturer, Children’s National Medical Center, Washington, DC, March 14, 2001.

20.Lifetime Achievement Award: from the Epilepsy Foundation of Michigan, August 2001.

21.Ring of Hope Award from the Pheasant Ring Foundation (November 2001)

22.Invited by Senator Patricia Birkholz to address the 2003 Michigan Legislative Children’s Caucus Meeting, Lansing, June 4, 2003 (joint House and Senate members)

23.Distinguished Lecturer, Human Biology Program, Stanford University, Palo Alto, CA, May 8, 2003

24.The Harry T. Chugani Scientific Scholar of Merit Award. Established by the Sturge-Weber Foundation in 2004. “This award is presented to an individual who displays the degree of commitment, curiosity, and collaboration that is the hallmark of Dr. Chugani’s professional career.”

25.Visiting Professor. Boston Children’s Hospital, Harvard University, Department of Nuclear Medicine, May 9-11, 2005. Two formal lectures, teaching session with neurology and nuclear medicine residents, informal discussions.

26.Named Lecture. The Alavi Lecture, University of Pennsylvania, “PET scanning in pediatric neurological disorders”, Philadelphia, September 13, 2005.

27.Invited Lecture. American Academy of Pediatrics National Conference 2005, Washington , DC. Section on Adoption and Foster Care October 10, 2005, “Neuroimaging, plasticity and early childhood experience” [Note: lecture covered by the press and referred to in USA Today on October 11, 2005].

28.Invited Guest and Lecturer. Invitation by Her Royal Highness Professor Doctor Princess Chulabhorn to celebrate her 48th birthday, October 22-24, Bangkok, Thailand.

EDUCATION:

High SchoolSt. Joseph's College, Hong Kong (1964-1968)

BaccalaureateLa Salle College, Philadelphia, PA (1968-1972)

B.A. (Magna Cum Laude)

DoctorateGeorgetown University School of Medicine,

Washington, D.C. (1972-1976)

M.D.

POSTGRADUATE TRAINING:

Pediatric InternChildren's Memorial Hospital

(Chicago)7/76-6/77

Pediatric ResidentGeorgetown University Hospital

(Washington, DC)7/77-6/78

Neurology ResidentGeorgetown University Hospital

(Washington, DC)7/78-6/80

Pediatric NeurologyGeorgetown University Hospital

Fellow(Washington, DC)7/80-6/81

Nuclear MedicineUCLA Medical Center7/90-6/92

Fellow*

*NOTE: this was achieved while being tenured faculty at the same time

PREVIOUS RESEARCH SUPPORT

1.USPHS Grant #DA02518 "Neurophysiological and Developmental Studies on

Opiates."

PI: J.R. Villablanca. Funded from September 30, 1981 to February 28, 1985

Co-investigator

2.Neuropsychiatric Institute BRSG award "Naloxone-induced Seizures:

Autoradiographic Mapping and Pharmacological Studies"

PI: H.T. Chugani. Funded from February 1, 19983 to January 31, 1984.

$4,860.

3.NIH Grant Po1 NS156454 "Neuroscience Research with Positron Emission

Tomography."

PI: M.E. Phelps. Funded from September 1, 1984 to August 31, 1989.

$4,572,420. Co-investigator.

4.Epilepsy Foundation of American Award AP840123 "Uncoupling of Hippocampal

Blood Flow from Metabolism during Kindled Seizures in the Rat."

PI: H.T. Chugani. March 1, 1984 to February 28, 1985. $14,908.

5.NINCDS Teacher Investigator Development Award 1 K07 NS00886.

July 1, 1984 to June 30, 1989.

PI: H.T. Chugani

$218,000.

6.NIH Grant NS 02808 "A Clinical Research Program for the Partial Epilepsies."

January 1, 1985 to December 31, 1989.

PI: J. Engel, Jr.

$3,325,680. Co-investigator

7.United Cerebral Palsy Association R-368-86 "Positron Emission Tomography

with 2-deoxy-2[18F] fluoro-D-glucose in children with cerebral palsy."

November 1, 1986 to October 31, 1989

PI: H.T. Chugani

$258,750.

8.NIH Grant 2 P01 NS 15654-09S1 (Supplement)

"Metabolic Maturation of the Brain".

PI: H.T. Chugani

Program Project Director: M.E. Phelps

May 1, 1988 to August 31, 1989

$301,932.

9.NIH Grant 2 P01 NS 15654 (years 11 to 15)

Program Project: "Neuroscience Research with PET"

Project II: "Metabolic Maturation of the Brain"

PI: H.T. Chugani

Budget for Project II: $960,856

Program Project Director: M.E. Phelps

Total Budget: $7,942,549

September 1, 1989 to August 31, 1994

10.Siemens Corporation

PET Research in Children

PI: H.T. Chugani

January 1, 1994 to December 31, 1996 Total Budget: $225,000

11.Leukemia Research Life, Inc.

Brain Tumor Metabolism

PI: H.T. Chugani

November 1, 1994 to October 31, 1995

Total Budget: $45,000.

12.Mental Illness Research Association

PET Studies in Autism

PI: H.T. Chugani

November 1, 1994 to October 31, 1995

Total Budget: $30,000.

13.MIRA-Mental Illness Research Association

$30,000 per year for years 1995, 1996, and 1997 for PET Studies of Autism

$25,000 year ongoing commitment beginning July 1997 for "Autism Research

Clinic" awarded to Harry T. Chugani and Diane C. Chugani

14.International Foundation for Alternating Hemiplegia

7/1/95 - 6/30/96$17,000

1/1/97 - 12/31/97$30,000

PI: Harry T. Chugani

15.Japanese Epilepsy Association Grant

"Functional PET Studies of Television-induced Epilepsy"

March 1995 to February 1998$100,000

PI: Harry T. Chugani

16.Pheasant Ring Community

$12,500 year ongoing commitment beginning July 1997 for “Autism Research Clinic”

Awarded to Harry T. Chugani and Diane C. Chugani

17.NIH Grant: 1 R13 NS38447-01

Sturge Weber Syndrome Consensus Conference

PI: Harry T. ChuganiCo-PI: Diane C. Chugani

Funded for period 4/1/99 – 3/31/00: Total award $45,000

18.Parke-Davis – Warner Lambert Company

Gabapentin in Partial Epilepsy in Infancy

PI: Harry T. Chugani

Funded for period 6/8/99 – 1/7/00

  1. NIH Grant 1 R01 HD34942

Brain serotonin synthesis in autism

PI: Diane C. ChuganiCo-PI: Harry T. Chugani

Funded for period 12/15/98 to 11/30/01; Total award: $758,181

12/15/98 to 11/30/99$251,578

12/1/99 to 11/30/00$245,265

12/1/00 to 11/30/01$251,641

20.NIH Grant: 1 R01 NS38324

Imaging tryptophan metabolism in tuberous sclerosis

PI: Diane C. ChuganiCo-PI: Harry T. Chugani

Funded for period 2/1/99 to 1/31/04; Total award $973,273

2/1/99 to 1/31/00$194,213

2/1/00 to 1/31/01$187,170

2/1/01 to 1/31/02$192,511

2/1/02 to 1/31/03$197,249

2/1/03 to 1/31/04$202,130

21.NIH grant R01 HD40007

Ontogeny of human GABA-A receptor complex measured with PET

PI: Otto MuzikCo-PI: Harry T. Chugani

Funded for period 9/29/00 – 9/28/03, Total award $550,000 direct costs

22.NIH Grant: R01 NS 34488

"Localization of Epileptic Foci with PET in Children"

Principal Investigator: Harry T. Chugani

Co-Principal Investigator: Diane C. Chugani

Funded for period December 1, 1996 to November 30, 1999

Total Award: $559,279.

12/1/96 to 11/30/99$198,000

12/1/96 to 11/30/99$179,985

12/1/96 to 11/30/99$180,525

Funded for period 9/15/00 to 8/31/05; Total award:

9/15/00 to 8/31/01$277,471

9/01/01 to 8/31/02$272,916

9/01/02 to 8/31/03$281,102

9/01/03 to 8/31/04$289,535

23. R21 DA015919-01 (Muzik)

Software tools for pediatric neuroimaging

PI: Otto Muzik

Co-Investigator: Harry T. Chugani

Funded for period 10/01/02-9/30/04Total award $300,000 direct costs

  1. Topiramate pharmacokinetics and tolerability in infants with seizures.

Johnson & Johnson Pharmaceutical Research & Development.

PI: Harry T. Chugani

1-21-03 to 12-31-03$142,000

25.Johnson & Johnson Pharmaceutical Inc.

Topiramate pharmacokinetics and tolerability in infants with seizures.

PI: Harry T. Chugani

Amount: $142,000

Duration of study: 2/1/03 – 1/31/04 (1 year)

26.Johnson & Johnson Pharmaceutical Inc.

Topiramate in human newborn

PI: Harry T. Chugani

Amount: $40,000

Duration of study: 5/1/03 – 4/30/04

27.Johnson & Johnson Pharmaceutical Inc.

Topiramate in infantile spasms

PI: Harry T. Chugani

Amount: $40,000

Duration of study: 5/1/03 – 4/30/04

28. U01 HD37261-04S2

Pediatric Pharmacology Research Unit

PI: Jacob Aranda

Subproject title: Early pharmacotherapy aimed at neuroplasticity in autism

Subproject PI: Diane C. Chugani

Co-Investigator: Harry T. Chugani

Funded for period 9/30/02 to 12/31/05 Total award $120,000 direct costs

29.NIH R01 NS 45151

Tryptophan metabolism in children with epilepsy

PI: Diane Chugani

Co-PI: Harry T. Chugani

January 1, 2004 to December 31, 2007, Total award $925,000 direct costs

CURRENT RESEARCH SUPPORT

30.NIH Grant: R01 NS 34488

"Localization of Epileptic Foci with PET in Children"

Principal Investigator: Harry T. Chugani

Funded for period 9/1/05 to 8/31/10; Total award $1,948,541

31.NIH Grant R01 NS045911 CHMC 367

Childhood absence epilepsy Rx PK-PD pharmacogenetics

PI: Tracy Glauser Subcontract PI: Harry T. Chugani

Funded period 9/30/03 – 10/31/08 Total award $17,336,053

Subcontract for 9/30/05 – 10/31/06: $45,816

Subcontract for 9/30/07 - 10/31/08: $65,773

Currently at no cost extension

32.RO1 NS41922

Longitudinal neuroimaging in Sturge-Weber syndrome

PI: C. Juhasz

Co-investigator: H.T. Chugani

July 1, 2008 to April 30, 2013

Total award: $990,000 direct costs

33. RO1 CA123451

Tryptophan metabolism in human brain tumors

Agency: NIH/National Cancer Institute

PI: C. Juhasz

Co-Investigator: H.T. Chugani

December 1, 2007 to November 30, 2012

Total award: $1,095,000 direct costs

34.“Structural and Functional neural correlates of early postnatal deprivation”

PI: Michael E. Behen, PhD

Mentor: Harry T. Chugani

NIH 1K08MH079176

9/3/07 - 7/31/12

Total Award: $733,409.

35."Early pharmacotherapy guided by biomarkers in autism"

Principal Investigator: DC Chugani PhD.

Co-Investigator: Harry T. Chugani

Agency: NINDS

Type U01 NS61264 Period: 2/1/08 - 1/31/13

Total award $5,800,000

36. Project SOFIA

Sponsor: Neuropharm

PI: Harry T. Chugani

Funded period 01/30/08 – 11/29/08

Total Award $59,142

37. Project EMMA

Sponsor: Neuropharm

PI: Harry T. Chugani

Funded period 09/15/08– 12/31/09

Total Award $39,671

Pending grant:

  1. "Epilepsy in Tuberous Sclerosis Complex"

Start/End Date: 7/1/07 - 6/30/12

Direct cost: $1,512,784

Total cost: $2,216,388

SERVICES PERFORMED

1.Grant reviewer for the National Science Foundation

2.Ad Hoc Reviewer for various journals (Annals of Neurology, Proceedings National Academy of Sciences, Journal of Neuroscience, Journal of Neuroendocrinology, Pediatric Research, Journal of Experimental Neurology, Neurology, New England Journal of

Medicine, Journal of Cerebral Blood Flow and Metabolism, Epilepsia, Journal of Nuclear Medicine, Journal of the Neurological Sciences, NeuroImage, Archives of Neurology, Brain, Biological Psychiatry).

3.Symposium chairman: Neuroimaging in pediatrics, Child Neurology Society

Boston 1986.

4.Invited member of Joint Committee on Research in Pediatric Neurology

(sponsored by Child Neurology Society).

5.Thesis Committee for Ph.D degree of the following students:

Randall A. Hawkins (Radiological Sciences, UCLA)

Magnus Dahlbom (Medical Physics, UCLA)

Fernando Gomez-Pinilla (Anatomy, UCLA)

Guido Germano (Radiological Sciences, UCLA)

Ronald See (Psychology, UCLA)

Daniel Valentino (Radiological Sciences, UCLA)

6.Grant reviewer for March of Dimes

National Institutes of Health Special Study Section

National Institutes of Health Neurology A Study Section (Ad Hoc 1997-1998)

National Institutes of Health BDCN-5 Study Section Standing Member

CHAIRMAN of NIH Study section BDCN-5 (1999-2002)

CHAIRMAN of NIH Study section Developmental Brain Disorders (DBD) (2003-2005)

Board of Scientific Counsel of NINDS (Ad Hoc reviewer of intramural research program, 2005)

Ad hoc reviewer February 2006 for Motor Function, Speech and Rehabilitation study (MFSR) section

Ad hoc reviewer for the National Research Council (UK)

Ad hoc reviewer for the Austrian Research Council

NIH special Study Section for Clinical Translational Science Awards (CTSA) (2006)

7.Nominations Committee (Child Neurology Society) 1988-1989

Research Committee (Child Neurology Society) 1989

Scientific Selection Committee (Child Neurology Society) 1989-1990

Scientific Selection Committee (American Academy of Neurology) 1989-1990,

1990-1991.

Scientific Selection Committee (International Society of Cerebral Blood Flow and

Metabolism) 1991

Organizing Committee: International Workshop on Infantile Spasms, Paris,

May 1991

Scientific Selection Committee (International Symposium on Cerebral Blood Flow

and Metabolism) 1993

Invited Member of the Scientific Committee of the International School of

Neurological Sciences, Italy

Editorial Board: Journal of Child Neurology (1991-present)

Editorial Board: Brain and Development (1994-present)

Editorial Board: Pediatric Neurology (1994-present)

Editorial Board: Journal of Developmental Disabilities (1997)

Editorial Board: Journal of Pediatric Neurology (2003-present)

Editorial Board: Neurology (January 2004-December 2005)

Childhood Epilepsy Committee (American Epilepsy Society) 1994-1996

Professional Advisory Board: Sturge-Weber Foundation (Executive Committee)

Scientific Selection Committee (Child Neurology Society) 1994-1996

President, Medical Board of the Alternating Hemiplegia Foundation, 1995-2003

Member, National Tuberous Sclerosis Association Professional Advisory Board

May 25, 1995 to present

Member, Scientific Program Committee, American Epilepsy Society, February

1997

Scientific Program Committee, International Child Neurology Association, 1998

Member, Professional Advisory Committee of the Epilepsy Foundation of Michigan

Member, Professional Advisory Board for the Pheasant Ring Foundation

Member of Scientific Committee, Child Neurology Section, International School of Neurological Sciences, Venice, Italy (2003-2006)

Member, Research Committee, Child Neurology Education and Research Foundation (2002-present)

Chairman, Professional Advisory Board, October 2005-present. The Sturge-Weber Foundation

Executive Board Member, International Child Neurology Association, 2006 - present

8.External Advisor on Center Grant Proposal (P50) entitled "Fetal Drug Exposure:

Risks, Interventions and Outcomes", submitted to the National Institute on Drug

Abuse by Massachusetts General Hospital, Harvard Medical School,

September 1996

9.Consultant on the Advisory Committee to the FDA’s Peripheral and Central Nervous System Committee action on the anticonvulsant drug vigabatrin. January 7-8, 2009, Washington, DC.

UNIVERSITY COMMITTEES

1.Pediatrics Quality Assurance Committee, UCLA (1987)

2.Grand Rounds Committee, Neurology Department, UCLA (1988)

3.Hospital Utilization Committee, UCLA (1990-1993)

4.Research Committee, Children's Hospital of Michigan (1993-1995; 199-2001)

5.Research Advisory Committee, Children's Hospital of Michigan (1993-1996)

  1. Internal Review Board, Children's Hospital of Michigan (1996-1998).
  1. Member, Internal Review Committee for Department of Neurology (1997)
  1. Member, Search Committee for Chief of Pediatric Neurosurgery (2001-2002)
  1. Member, Wayne State University Imaging Research Oversight Committee (2001 to present)

10, Member, Internal Review Committee for Department of Neurology (2002)

11. Member, Promotion and Tenure Committee, Department of Neurology

12.Co-Chair, Search Committee for CHM CRCM Director (2005-2006)

TEACHING ACTIVITIES (for residents, fellows and medical students)

1.Ward attending in pediatric neurology; 3 months each year, consists of daily

teaching rounds lasting 2 hours (1981-1993). UCLA

2.Pediatric Neurology Clinic: one afternoon each week (1981-1993). UCLA

3.Pediatric Neurology Clinic: Olive View Medical Center, 2 mornings each month

(July 1981-June 1987). Los Angeles

4.Pediatric admission residents' conference (Intake Conference): 2 times per week

for 3 months of the year. (1981-1993). UCLA

5.Pediatric Neurology Residents' Clinic: 1 afternoon each month (1981-1983).

UCLA

6.Neurology Clerkship NE-011: 4 students, 2 weeks each year, 2 hours each day

(1981-1988). UCLA

7.Fundamentals of Clinical Medicine: Instruction in the neurological examination,

2nd year medical students, 2 afternoons each year (1981-1993). UCLA

8.Pediatric Core Lectures (Pediatric Neurology): one each 2 months (1981-1993).

UCLA

9.Instruction in interpreting pediatric evoked potentials recordings: 1 hour each week

(1981-1991). UCLA

10.Pediatric Neurology Journal Club: 1 hour each month (1983-1986). UCLA

11.Pediatric Neurology Research Conference: 1 hour each month (1984-1991).

UCLA

12. Pediatric Neurology Clinic Review Conference: 1-2 hours each week (1984-1991).

UCLA

13.Miscellaneous invited lectures at UCLA and other institutions. (List available upon

request).

14.Ward attending in pediatric neurology: 1 month each year, consists of daily

teaching rounds lasting 3-4 hours (1994-1999).

2-3 months each year of ward attending Children's Hospital of Michigan

Wayne State University. (1999-Present)

15.Epilepsy Surgery Conference: 1 hour each week (1994-Present).

  1. Pediatric Neurology Conference (1999-Present).

PUBLICATIONS

RESEARCH PAPERS (refereed publications)

1.Kasbekar DK, Chugani H: Role of calcium ion in 'in vitro' gastric acid secretion.

In Gastric Hydrogen Ion Secretion Marcel-Dekker, 187-211, 1976.

2.Chugani HT, Rosemblat AM, Lavenstein BL, Palumbo FM, Luessenhop AJ,

Manz HJ: Childhood medulloblastoma presenting with hemorrhage. Child's Brain

11:135-140, 1984.

3.Chugani HT, Akermann RF, Chugani DC, Engel J Jr: Opioid-induced epileptogenic phenomena in rats: anatomical, behavioral, and electroencephalographic studies.

Ann Neurol 15: 361-368, 1984.

4.Phelps ME, Barrio JR, Huang S-C, Keen RE, Chugani Chugani HT, Mazziotta JC:

Criteria for the tracer kinetic measurement of cerebral protein synthesis in humans

with positron emission tomography. Ann Neurol 15 (suppl): S192-S202, 1984.

5.Shields WD, Lake JL, Chugani HT: Amantadine in the treatment of refractory

epilepsy in childhood: Report of an open trial in 10 patients. Neurology 35:

579-581, 1985.

6.Furman JM, Baloh RW, Chugani HT, Waluch V, Bradley WG: Infantile cerebellar

atrophy. Ann Neurol 17: 399-402, 1985.

7.Chugani HT, Phelps ME: Maturational changes of cerebral function in the infant

determined by FDG positron emission tomography. Science 231: 840-843, 1986.

8.Chugani HT, Mazziotta JC, Engel J Jr., Phelps ME: Lennox-Gastaut syndrome:

Metabolic subtypes determined by 18FDG positron emission tomography. Ann

Neurol 21: 4-13, 1987.

9.Chugani HT, Phelps ME, Mazziotta JC: Positron emission tomography study of

human brain functional development. Ann Neurol 22: 487-497, 1987.

10.Chugani HT, Shewmon DA, Peacock WJ, Shields WD, Mazziotta JC, Phelps ME:

Surgical treatment of intractable neonatal-onset seizures: The role of positron

emission tomography. Neurology 38: 1178-1188, 1988.

11.Chugani HT, Phelps ME: PET in children with seizures. Applied Radiology

17: 37-49, 1988.

12.Chugani HT, Mazziotta JC, Phelps ME: Sturge-Weber syndrome: A study of

cerebral glucose utilization with positron emission tomography. J. Pediatrics

114: 244-253, 1989.

13.Olson DM, Chugani HT, Shewmon DA, Phelps ME, Peacock WJ:

Electrocorticographic confirmation of focal positron emission tomographic

abnormalities in children with intractable epilepsy. Epilepsia 31: 731-739, 1990.

14.Feinberg I, Thode HC, Chugani HT, March JD: Gamma distribution model

describes maturational curves for delta wave amplitude, cortical metabolic rate and

synaptic density. J. Theor Biol. 142: 149-161, 1990.

15.Chugani HT, Shewmon DA, Shields WD, Peacock WJ, Phelps ME: Pediatric

Epilepsy surgery: Pre-and post-operative evaluation with PET. J. Epilepsy 3

(suppl): 141-155, 1990.

16.Shewmon DA, Shields WD, Chugani HT, Peacock WJ: Contrasts between

pediatric and adult epilepsy surgery: Rationale and strategy for focal resection.

J. Epilepsy 3 (Suppl): 141-155, 1990.

17.Shields WD, Shewmon DA, Chugani HT, Peacock WJ: The role of surgery in the

treatment of infantile spasms. J. Epilepsy 3 (Suppl): 321-324, 1990.

18.Chugani HT, Shields WD, Shewmon DA, Olson DM, Phelps ME, Peacock WJ:

Infantile spasms: I. PET identifies focal cortical dysgenesis in cryptogenic cases