Supplementary DataTable 1: List of genes that were up regulated or down regulated by progesterone treatment in the microarray experiments.

Up regulated genes

ORF/Gene

/

Functional groups and known gene functions

/

Average fold induction

Cell type differentiation and localization

DUR1,2 / Urea amidolyase (by homology); 1813 aa; 200419 Da; pI=5.9 / +1.7
IPF3370 / Similar to Saccharomyces cerevisiae Pre1p 20S proteasome subunit C11(beta4) (by homology); 196 aa; 22019 Da; pI=6.9 / +1.6
UBC13 / E2 ubiquitin-conjugating enzyme (by homology); 169 aa; 19057 Da; pI=4.8 / +1.6
SCL1 / Proteasome subunit YC7alpha (by homology); 247 aa; 27451 Da; pI=7.3 / +1.6
SLY1 / Hydrophilic suppressor of YPT1 and member of the Sec1p family (by homology); 623 aa; 70257 Da; pI=4.9 / +1.8
HSP90 / Heat shock protein; 707 aa; 80823 Da; pI=4.5 / +1.7
CPR6 / Cyclophylin (by homology); 369 aa; 40740 Da; pI=6.3 / +1.5
SSA4 / Cahsp70 mRNA for heat shock; 656 aa; 70324 Da; pI=4.8 / +4.0
KAR2 / DnaK-type molecular chaperone (by homology); 687 aa; 74562 Da; pI=4.6 / +1.7
Protein activity regulation
DUR,2 / Urea amidolyase (by homology); 1813 aa; 200419 Da; pI=5.9 / +1.7
SSA4 / Cahsp70 mRNA for heat shock; 656 aa; 70324 Da; pI=4.8 / +4.0
FAB1 / Phosphatidylinositol 3-phosphate 5-kinase (by homology); 2379 aa; 269066 Da; pI=6.8 / +1.5
Protein synthesis
DUR1,2 / Urea amidolyase (by homology); 1813 aa; 200419 Da; pI=5.9 / +1.7
CPR6 / Cyclophylin (by homology); 369 aa; 40740 Da; pI=6.3 / +1.5
KAR2 / DnaK-type molecular chaperone (by homology); 687 aa; 74562 Da; pI=4.6 / +1.7
Protein with cofactor requirement
IPF20164 / Putative kynurenine aminotransferase (by homology); 453 aa; 51178 Da; pI=5.8 / +1.6
CDR2 / Candida albicans drug resistance protein 2; 1499 aa; 168965 Da; pI=7 / +4.6
MBF1 / Multiprotein bridging factor mediates GCN4-dependent transcriptional activation (by homology); 151 aa; 16292 Da; pI=10.8 / +1.7

KAR2

/ DnaK-type molecular chaperone (by homology); 687 aa; 74562 Da; pI=4.6 / +1.7
CDR1 / Multidrug resistance protein (by homology); 1501 aa; 169953 Da; pI=6.9 / +7.3

HSP60

/ Heat Shock Protein 60 (HSP60); 566 aa; 60126 Da; pI=4.9 / +1.7
SSA4 / Cahsp70 mRNA for heat shock; 656 aa; 70324 Da; pI=4.8 / +4.0
Cell rescue defense and virulence
GPX1 / Glutathione peroxidase (by homology); 161 aa; 18103 Da; pI=7.2 / +1.7
DDR48 / Stress protein (by homology); 212 aa; 22615 Da; pI=4.1 / +1.6
IPF3370 / Similar to Saccharomyces cerevisiae Pre1p 20S proteasome subunit C11(beta4) (by homology); 196 aa; 22019 Da; pI=6.9 / +1.6

GRP2

/ Reductase (by homology); 341 aa; 37634 Da; pI=6.4 / +2.5
UBC13 / E2 ubiquitin-conjugating enzyme (by homology); 169 aa; 19057 Da; pI=4.8 / +1.6
CDR2 / Candida albicans drug resistance protein 2; 1499 aa; 168965 Da; pI=7 / +4.6
SCL1 / Proteasome subunit YC7alpha (by homology); 247 aa; 27451 Da; pI=7.3 / +1.6
SSA4 / Cahsp70 mRNA for heat shock; 656 aa; 70324 Da; pI=4.8 / +4.0
PRE6 / 20S proteasome subunit; 209 aa; 23186 Da; pI=8.6 / +1.5
KAR2 / dnaK-type molecular chaperone (by homology); 687 aa; 74562 Da; pI=4.6 / +1.7
HSP12 / Heat shock protein (by homology); 127 aa; 13325 Da; pI=4.7 / +3.5
CDR1 / Multidrug resistance protein (by homology); 1501 aa; 169953 Da; pI=6.9 / +7.3
MDR1 / Mac1p interacting protein (by homology); 942 aa; 108278 Da; pI=5.3 / +1.6
HSP60 / Heat Shock Protein 60 (HSP60); 566 aa; 60126 Da; pI=4.9 / +1.7
RTA3 / Unknown function; 464 aa; 52289 Da; pI=5.7 / +1.7
MXR1 / Methionine sulfoxide reductase; 185 aa; 21106 Da; pI=6.9 / +1.8
Subcellular and organ localization
GPX1 / Glutathione peroxidase (by homology); 161 aa; 18103 Da; pI=7.2 / +1.7
LEU2 / Isopropyl malate dehydrogenase; 373 aa; 40086 Da; pI=4.9 / +1.5
SGT2 / Small glutamine-rich tetratricopeptide repeat containing protein by homology; 344 aa; 36462 Da; pI=4.6 / +1.6
CDR2 / Candida albicans drug resistance protein 2; 1499 aa; 168965 Da; pI=7 / +4.6
SLY1 / Hydrophilic suppressor of YPT1 and member of the Sec1p family (by homology); 623 aa; 70257 Da; pI=4.9 / +1.8
ILV5 / Ketol-acid reducto-isomerase (by homology); 400 aa; 44848 Da; pI=6.5 / +1.9
STF2 / ATP synthase regulatory factor (by homology); 89 aa; 10495 Da; pI=9.8 / +1.6
RTA3 / Unknown function; 464 aa; 52289 Da; pI=5.7 / +1.7
UBC13 / E2 ubiquitin-conjugating enzyme (by homology); 169 aa; 19057 Da; pI=4.8 / +1.6
PRB1 / Putative endoprotease B; regulated by heat, carbon source (GlcNAc-induced), nitrogen, macrophage response, human neutrophils; putative D200-H232-S389 catalytic triad; similar to (but does not replace) S. cerevisiae vacuolar B protease Prb1p / +1.8
SSA4 / Cahsp70 mRNA for heat shock; 656 aa; 70324 Da; pI=4.8 / +4.0
GDH3 / NADP-glutamate dehydrogenase (by homology); 456 aa; 49577 Da; pI=5.6 / +10.1
GLN1 / Glutamate-ammonia ligase (by homology); 373 aa; 41721 Da; pI=6.0 / +1.8
AAT21 / Aspartate aminotransferase (by homology); 416 aa; 46038 Da; pI=9 / +1.6
IPF20016 / Similar to Saccharomyces cerevisiae Sec63p ER protein-translocation complex subunit (by homology); 673 aa; 76572 Da; pI=4.9 / +1.6
IPF6566 / Unknown function; 70 aa; 8139 Da; pI=3.3 / +1.5
TPI1 / Triose phosphate isomerase; 248 aa; 26611 Da; pI=5.8 / +1.7
KAR2 / DnaK-type molecular chaperone (by homology); 687 aa; 74562 Da; pI=4.6 / +1.7
HSP60 / Heat Shock Protein 60 (HSP60); 566 aa; 60126 Da; pI=4.9 / +1.7
Protein fate
IPF3370 / Similar to Saccharomyces cerevisiae Pre1p 20S proteasome subunit C11(beta4) (by homology); 196 aa; 22019 Da; pI=6.9 / +1.6
UBC13 / E2 ubiquitin-conjugating enzyme (by homology); 169 aa; 19057 Da; pI=4.8 / +1.6
SLY1 / Hydrophilic suppressor of YPT1 and member of the Sec1p family (by homology); 623 aa; 70257 Da; pI=4.9 / +1.8
STF2 / ATP synthase regulatory factor (by homology); 89 aa; 10495 Da; pI=9.8 / +1.6
KAR2 / DnaK-type molecular chaperone (by homology); 687 aa; 74562 Da; pI=4.6 / +1.7

RPN1

/ 26S proteasome regulatory subunit (by homology); 994 aa; 109937 Da; pI=4.4 / +1.9
HSP60 / Heat Shock Protein 60 (HSP60); 566 aa; 60126 Da; pI=4.9 / +1.7
PRB1 / Protease B. vacuolar (by homology); 493 aa; 52109 Da; pI=5.5 / +1.8
SSA4 / Cahsp70 mRNA for heat shock; 656 aa; 70324 Da; pI=4.8 / +4.0
IPF20016 / Similar to Saccharomyces cerevisiae Sec63p ER protein-translocation complex subunit (by homology); 673 aa; 76572 Da; pI=4.9 / +1.6
Energy
LEU2 / Isopropyl malate dehydrogenase; 373 aa; 40086 Da; pI=4.9 / +1.5
STF2 / ATP synthase regulatory factor (by homology); 89 aa; 10495 Da; pI=9.8 / +1.6
IDP1 / Isocitrate dehydrogenase, cytosolic (by homology); 433 aa; 48562 Da; pI=7 / +2.1
SHM2 / Serine hydroxyl-methyl-transferase precursor. mitochondrial (by homology); 470 aa; 52038 Da; pI=7.2 / +2.0
SER33 / Phosphoglycerate dehydrogenase (by homology); 463 aa; 50358 Da; pI=5.9 / +1.5
PDC12 / PyruvatedecarboxylaseI. exon 2 (by homology); 514 aa; 55850 Da; pI=7.1 / +1.5
GND1 / 6-phosphogluconate dehydrogenase; 517 aa; 56910 Da; pI=6.5 / +1.6
GLG2 / Self-glucosylating initiator of glycogen synthesis (by homology); 361 aa; 41982 Da; pI=4.6 / +1.6

ADH1

/ Alcohol dehydrogenase (by homology); 434 aa; 46064 Da; pI=8.2 / +1.8
PDC11 / Pyruvate decarboxylase (by homology); 567 aa; 62441 Da; pI=5.3 / +2.0
IDP1 / Isocitrate dehydrogenase. cytosolic (by homology); 433 aa; 48562 Da; pI=7 / +2.1
TPI1 / Triose phosphate isomerase; 248 aa; 26611 Da; pI=5.8 / +1.7
Metabolism
LEU2 / Isopropyl malate dehydrogenase; 373 aa; 40086 Da; pI=4.9 / +1.5

MIS11

/ Mitochondrial C1-tetrahydrofolate synthase precursor (by homology); 946 aa; 102178 Da; pI=6.5 / +1.5
ILV5 / Ketol-acid reducto-isomerase (by homology); 400 aa; 44848 Da; pI=6.5 / +1.9
SSA4 / Cahsp70 mRNA for heat shock; 656 aa; 70324 Da; pI=4.8 / +4.0
HSP12 / Heat shock protein (by homology); 127 aa; 13325 Da; pI=4.7 / +3.5
CDC19 / Pyruvate kinase (by homology); 504 aa; 55444 Da; pI=7 / +1.7
IPF2837 / Putative cystathionine gamma-synthase (by homology); 383 aa; 42406 Da; pI=6.0 / +2.0
MXR1 / Methionine sulfoxide reductase; 185 aa; 21106 Da; pI=6.9 / +1.8
SHM2 / Serine hydroxymethyltransferase precursor. mitochondrial (by homology); 470 aa; 52038 Da; pI=7.2 / +2.0
GDH3 / NADP-glutamate dehydrogenase (by homology); 456 aa; 49577 Da; pI=5.6 / +10.1
GLN1 / Glutamate-ammonia ligase (by homology); 373 aa; 41721 Da; pI=6.0 / +1.8
AAT21 / Aspartate aminotransferase (by homology); 416 aa; 46038 Da; pI=9 / +1.6
TPI1 / Triose phosphate isomerase; 248 aa; 26611 Da; pI=5.8 / +1.7
Biogenesis
UBC13 / E2 ubiquitin-conjugating enzyme (by homology); 169 aa; 19057 Da; pI=4.8 / +1.6
SLY1 / Hydrophilic suppressor of YPT1 and member of the Sec1p family (by homology); 623 aa; 70257 Da; pI=4.9 / +1.8

STF2

/ ATP synthase regulatory factor (by homology); 89 aa; 10495 Da; pI=9.8 / +1.6
SSA4 / Cahsp70 mRNA for heat shock; 656 aa; 70324 Da; pI=4.8 / +4.0
KAR2 / DnaK-type molecular chaperone (by homology); 687 aa; 74562 Da; pI=4.6 / +1.7
HSP60 / Heat Shock Protein 60 (HSP60); 566 aa; 60126 Da; pI=4.9 / +1.7
AAT21 / Aspartate aminotransferase (by homology); 416 aa; 46038 Da; pI=9 / +1.6
TPI1 / Triose phosphate isomerase; 248 aa; 26611 Da; pI=5.8 / +1.7
Cell cycle and DNA processing
UBC13 / E2 ubiquitin-conjugating enzyme (by homology); 169 aa; 19057 Da; pI=4.8 / +1.6
SSA4 / CaHsp70 mRNA for heat shock; 656 aa; 70324 Da; pI=4.8 / +4.0
KAR2 / DnaK-type molecular chaperone (by homology); 687 aa; 74562 Da; pI=4.6 / +1.7
MXR1 / Methionine sulfoxide reductase; 185 aa; 21106 Da; pI=6.9 / +1.8
IPF6566 / Unknown function; 70 aa; 8139 Da; pI=3.3 / +1.5
ALS1 / Agglutinin-like protein. 3-prime end; 828 aa; 86543 Da; pI=3.9 / +5.8
Cell fate
UBC13 / E2 ubiquitin-conjugating enzyme (by homology); 169 aa; 19057 Da; pI=4.8 / +1.6
SLY1 / Hydrophilic suppressor of YPT1 and member of the Sec1p family (by homology); 623 aa; 70257 Da; pI=4.9 / +1.8
CPR6 / Cyclophylin (by homology); 369 aa; 40740 Da; pI=6.3 / +1.5
SCL1 / Proteasome subunit YC7alpha (by homology); 247 aa; 27451 Da; pI=7.3 / +1.6
KAR2 / DnaK-type molecular chaperone (by homology); 687 aa; 74562 Da; pI=4.6 / +1.7
Interaction with cellular environment
UBC13 / E2 ubiquitin-conjugating enzyme (by homology); 169 aa; 19057 Da; pI=4.8 / +1.6
CDR2 / Candida albicans drug resistance protein 2; 1499 aa; 168965 Da; pI=7 / +4.6
CPR6 / cyclophylin (by homology); 369 aa; 40740 Da; pI=6.3 / +1.5
IPF6629 / Unknown function; 176 aa; 19258 Da; pI=5.0 / +1.5
KAR2 / DnaK-type molecular chaperone (by homology); 687 aa; 74562 Da; pI=4.6 / +1.7
CDR1 / Multidrug resistance protein (by homology); 1501 aa; 169953 Da; pI=6.9 / +7.3
Cellular transport
UBC13 / E2 ubiquitin-conjugating enzyme (by homology); 169 aa; 19057 Da; pI=4.8 / +1.6
CDR2 / Candida albicans drug resistance protein 2; 1499 aa; 168965 Da; pI=7 / +4.6
KAR2 / DnaK-type molecular chaperone (by homology); 687 aa; 74562 Da; pI=4.6 / +1.7
CDR1 / Multidrug resistance protein (by homology); 1501 aa; 169953 Da; pI=6.9 / +7.3
MDR1 / Mac1p interacting protein (by homology); 942 aa; 108278 Da; pI=5.3 / +1.6
IPF20016 / Similar to Saccharomyces cerevisiae Sec63p ER protein-translocation complex subunit (by homology); 673 aa; 76572 Da; pI=4.9 / +1.6
Cell type differentiation
SLY1 / Hydrophilic suppressor of YPT1 and member of the Sec1p family (by homology); 623 aa; 70257 Da; pI=4.9 / +1.8
SCL1 / Proteasome subunit YC7alpha (by homology); 247 aa; 27451 Da; pI=7.3 / +1.6
HSP90 / Heat shock protein; 707 aa; 80823 Da; pI=4.5 / +1.7
Cell type localization
CPR6 / Cyclophylin (by homology); 369 aa; 40740 Da; pI=6.3 / +1.5
SSA4 / Cahsp70 mRNA for heat shock; 656 aa; 70324 Da; pI=4.8 / +4.0
KAR2 / DnaK-type molecular chaperone (by homology); 687 aa; 74562 Da; pI=4.6 / +1.7
Cellular communication
CPR6 / Cyclophylin (by homology); 369 aa; 40740 Da; pI=6.3 / +1.5
CDC19 / Pyruvate kinase (by homology); 504 aa; 55444 Da; pI=7 / +1.7
Development
SCL1 / Proteasome subunit YC7alpha (by homology); 247 aa; 27451 Da; pI=7.3 / +1.6
SSA4 / Cahsp70 mRNA for heat shock; 656 aa; 70324 Da; pI=4.8 / +4.0
PRE6 / 20S proteasome subunit; 209 aa; 23186 Da; pI=8.6 / +1.5
KAR2 / DnaK-type molecular chaperone (by homology); 687 aa; 74562 Da; pI=4.6 / +1.7
HSP60 / Heat Shock Protein 60 (HSP60); 566 aa; 60126 Da; pI=4.9 / +1.7
Development
SCL1 / Proteasome subunit YC7alpha (by homology); 247 aa; 27451 Da; pI=7.3 / +1.6
SSA4 / Cahsp70 mRNA for heat shock; 656 aa; 70324 Da; pI=4.8 / +4.0
PRE6 / 20S proteasome subunit; 209 aa; 23186 Da; pI=8.6 / +1.5
KAR2 / DnaK-type molecular chaperone (by homology); 687 aa; 74562 Da; pI=4.6 / +1.7
HSP60 / Heat Shock Protein 60 (HSP60); 566 aa; 60126 Da; pI=4.9 / +1.7
Up regulated genes of unknown functions- Not categorized into any functional groups (Classification not clear)
SSA4 / Cahsp70 mRNA for heat shock; 656 aa; 70324 Da; pI=4.8 / +4.0
MBF1 / Multiprotein bridging factor mediates GCN4-dependent transcriptional activation (by homology); 151 aa; 16292 Da; pI=10.8 / +1.7
KAR2 / dnaK-type molecular chaperone (by homology); 687 aa; 74562 Da; pI=4.6 / +1.7
IPF16253 / Unknown function; 275 aa; 30282 Da; pI=4.8 / +1.9
IPF14282 / Similar to mucin proteins (by homology); 1309 aa; 136490 Da; pI=5.5 / +1.5
IPF14895 / Unknown function; 151 aa; 15988 Da; pI=8.3 / +2.0
IFU5 / Unknown function; 236 aa; 26045 Da; pI=4.3 / +1.9
IPF7109 / Unknown function; 191 aa; 20545 Da; pI=6.4 / +1.7
1-APR / Aspartyl protease; 419 aa; 45447 Da; pI=4.4 / +1.6
INO1 / Myo-inositol-1-phosphate synthase; 520 aa; 57779 Da; pI=5.2 / +2.4
IPF6881 / Putative phosphatidyl synthase; 597 aa; 66372 Da; pI=5.2 / +2.1
ALS1.3EOC / Agglutinin-like protein. 3-prime end; 828 aa; 86543 Da; pI=3.9 / +5.8
AAF1 / Adhesion and aggregation mediating surface antigen; 612 aa; 68794 Da; pI=10.0 / +1.7
IPF18076.3F / Thiol-specific antioxidant-like protein. 3-prime end (by homology); 52 aa; 5979 Da; pI=4.5 / +1.7

Down regulated genes

ORF/Gene / Functional groups and known gene functions / Average fold repression
Biogenesis
AAT2 / Aspartate aminotransferase (by homology); 353 aa; 40364 Da; pI=6.4 / -1.6
ODC1 / Ornithine decarboxylase; 473 aa; 52905 Da; pI=5.5 / -1.6
SIK1 / Nucleolar protein involved in pre-rRNA processing (by homology); 516 aa; 57899 Da; pI=9.8 / -2.2
NSR1 / Nuclear localization sequence binding protein (by homology); 400 aa; 43524 Da; pI=4.3 / -2.1
IPF5185 / Putative cell wall protein (by homology); 533 aa; 54278 Da; pI=4.5 / -4.5
ALD5 / Aldehyde dehydrogenase (NAD+) (by homology); 499 aa; 54011 Da; pI=5.4 / -1.6
HXT61 / Sugar transporter; 550 aa; 61514 Da; pI=6.0 / -1.8
Metabolism
AAT22 / Aspartate aminotransferase (by homology); 353 aa; 40364 Da; pI=6.4 / -1.6
IPF7366 / Arginyl-tRNA synthetase; 622 aa; 70816 Da; pI=6.1 / -1.6
ODC1 / Ornithine decarboxylase; 473 aa; 52905 Da; pI=5.5 / -1.6
CHT2 / Chitinase 2 precursor; 583 aa; 60851 Da; pI=4.4 / -2.0
IMH3 / IMP dehydrogenase. exon 2; 371 aa; 39795 Da; pI=7.2 / -1.6
ALD5 / Aldehyde dehydrogenase (NAD+) (by homology); 499 aa; 54011 Da; pI=5.4 / -1.6
ERG1
/ Squalene epoxidase; 496 aa; 55298 Da; pI=9 / -1.6
URA7 / CTP synthase 1 (by homology); 573 aa; 64048 Da; pI=6.4 / -2.0
HXT61 / Sugar transporter; 550 aa; 61514 Da; pI=6.0 / -1.8
Cellular communication
NOG1 / Nucleolar G-protein (by homology); 640 aa; 73535 Da; pI=9.5 / -1.6
Protein synthesis
GCD10 / Translation initiation factor eIF3 RNA-binding subunit (by homology); 453 aa; 51182 Da; pI=7 / -1.6
IPF7366 / Arginyl-tRNA synthetase; 622 aa; 70816 Da; pI=6.1 / -1.6
ARC1
/ G4 nucleic acid binding protein (by homology); 369 aa; 40947 Da; pI=9.3 / -1.5
BMS1 / Probable membrane protein involved in bud site selection (by homology); 1210 aa; 139302 Da; pI=5.4 / -1.5
TEF4 / Translation elongation factor eEF1 (by homology); 419 aa; 47537 Da; pI=8.9 / -1.5
TIF1 / Translation initiation factor; 397 aa; 44599 Da; pI=5.0 / -1.9
RPL23B.3 / Ribosomal protein L23.e. 3-prime end (by homology); 123 aa; 13093 Da; pI=10.7 / -1.5
RPS10.3 / Ribosomal protein. 3-prime end (by homology); 113 aa; 12995 Da; pI=10.1 / -1.5
Sub-cellular localization
GCD10 / Translation initiation factor eIF3 RNA-binding subunit (by homology); 453 aa; 51182 Da; pI=7 / -1.6
ODC1 / Ornithine decarboxylase; 473 aa; 52905 Da; pI=5.5 / -1.6
TIF1
/ Translation initiation factor; 397 aa; 44599 Da; pI=5.0 / -1.9
IMH3 / IMP dehydrogenase. exon 2; 371 aa; 39795 Da; pI=7.2 / -1.6
FTR1 / High affinity iron permease; 381 aa; 42505 Da; pI=8.8 / -1.6
ALD5 / Aldehyde dehydrogenase (NAD+) (by homology); 499 aa; 54011 Da; pI=5.4 / -1.6
ERG1 / Squalene epoxidase; 496 aa; 55298 Da; pI=9 / -1.6
RPA190 / DNA-directed RNA polymerase I (by homology); 1665 aa; 186271 Da; pI=6.1 / -2.1
TEF4 / Translation elongation factor eEF1 (by homology); 419 aa; 47537 Da; pI=8.9 / -1.5
BMS1 / Probable membrane protein involved in bud site selection (by homology); 1210 aa; 139302 Da; pI=5.4 / -1.5
HXT61 / Sugar transporter; 550 aa; 61514 Da; pI=6.0 / -1.8
RPS10.3 / Ribosomal protein. 3-prime end (by homology); 113 aa; 12995 Da; pI=10.1 / -1.5
RPL23B.3 / Ribosomal protein L23.e. 3-prime end (by homology); 123 aa; 13093 Da; pI=10.7 / -1.5
Transcription
GCD10 / Translation initiation factor eIF3 RNA-binding subunit (by homology); 453 aa; 51182 Da; pI=7 / -1.6
RPA190 / DNA-directed RNA polymerase I (by homology); 1665 aa; 186271 Da; pI=6.1 / -2.1
URA7 / CTP synthase 1 (by homology); 573 aa; 64048 Da; pI=6.4 / -2.0
BMS1 / Probable membrane protein involved in bud site selection (by homology); 1210 aa; 139302 Da; pI=5.4 / -1.5
Cellular transport
FTR2 / High affinity iron permease; 382 aa; 42597 Da; pI=9.2 / -1.5
IMH3 / IMP dehydrogenase. exon 2; 371 aa; 39795 Da; pI=7.2 / -1.6
FTR1 / High affinity iron permease; 381 aa; 42505 Da; pI=8.8 / -1.6
ALD5 / Aldehyde dehydrogenase (NAD+) (by homology); 499 aa; 54011 Da; pI=5.4 / -1.6
CTR1 / Copper transport protein; 251 aa; 27859 Da; pI=6.9 / -1.5
HXT61 / Sugar transporter; 550 aa; 61514 Da; pI=6.0 / -1.8
RPL23B.3 / Ribosomal protein L23.e. 3-prime end (by homology); 123 aa; 13093 Da; pI=10.7 / -1.5
Interaction with cellular environment
FTR2 / High affinity iron permease; 382 aa; 42597 Da; pI=9.2 / -1.5
HXT61 / Sugar transporter; 550 aa; 61514 Da; pI=6.0 / -1.8
FTR1 / High affinity iron permease; 381 aa; 42505 Da; pI=8.8 / -1.6
Protein with cofactor required
IPF7366 / Arginyl tRNA synthase; 622 aa; 70816 Da; pI 6.1 / -1.6
TIF1 / Translation initiation factor; 397 aa; 44599 Da; pI=5.0 / -1.9
SIK1 / Nucleolar protein involved in pre-rRNA processing (by homology); 516 aa; 57899 Da; pI=9.8 / -2.2
BMS1 / Probable membrane protein involved in bud site selection (by homology); 1210 aa; 139302 Da; pI=5.4 / -1.5
ALD5 / Aldehyde dehydrogenase (NAD+) (by homology); 499 aa; 54011 Da; pI=5.4 / -1.6
RPA190 / DNA-directed RNA polymerase I (by homology); 1665 aa; 186271 Da; pI=6.1 / -2.1
Protein activity regulation
ZPR1 / Zinc finger protein (by homology); 491 aa; 55020 Da; pI=4.5 / -2.0
TIF1 / Translation initiation factor; 397 aa; 44599 Da; pI=5.0 / -1.9
Energy
NDH1 / Mitochondrial NADH dehydrogenase; 574 aa; 63566 Da; pI=9.1 / -1.7
Cell cycle and DNA processing
SIK1 / Nucleolar protein involved in pre-rRNA processing (by homology); 516 aa; 57899 Da; pI=9.8 / -2.2
CHT2 / Chitinase 2 precursor; 583 aa; 60851 Da; pI=4.4 / -2.0
TIF1 / Translation initiation factor; 397 aa; 44599 Da; pI=5.0 / -1.9
URA7 / CTP synthase 1 (by homology); 573 aa; 64048 Da; pI=6.4 / -2.0
Cell fate and development
TIF1 / Translation initiation factor; 397 aa; 44599 Da; pI=5.0 / -1.9
RPL23B.3 / Ribosomal protein L23.e. 3-prime end (by homology); 123 aa; 13093 Da; pI=10.7 / -1.5
RPS10.3 / Ribosomal protein. 3-prime end (by homology); 113 aa; 12995 Da; pI=10.1 / -1.5
Down regulated genes of unknown functions - Not categorized into any functional groups(Classification not clear)
TIF1 / Translation initiation factor; 397 aa; 44599 Da; pI=5.0 / -1.9
IPF11182.3EOC / Unknown function. 3-prime end; 1653 aa; 188782 Da; pI=4.9 / -1.5
IPF18641 / Unknown function. exon 2; 620 aa; 71011 Da; pI=9.5 / -1.6
IPF16368.5F / Unknown function. 5-prime end; 838 aa; 95155 Da; pI=5.9 / -1.8
FRE30.3 / Strong similarity to ferric reductase Fre2p. 3-prime end (by homology); 421 aa; 48451 Da; pI=7.9 / -1.5
IPF15581 / Unknown function; 139 aa; 14358 Da; pI=9.6 / -1.5
IPF15977 / Unknown function; 421 aa; 47119 Da; pI=6.5 / -1.7
IPF5330 / Unknown function; 117 aa; 13149 Da; pI=10.1 / -1.6
IPF1548 / Unknown function; 162 aa; 18413 Da; pI=7.5 / -2.0

This table contains the list of genes found to be up-regulated or down-regulated by progesterone treatment in the microarray experiments. The known functions of these genes, the functional categories that they belong to, and their average fold induction /repression values are also shown. Functional classification of genes was done using the MIPS and CYGD databases ( and /proj/yeast/index.jsp). In order to avoid redundancy in gene/ORF appearing in more than one class, some of the functional categories are merged.