Ingmar Skoog
Ten most important publications (IS)
1. Skoog I, Nilsson L, Palmertz B, Andreasson L-A, Svanborg A. (1993) A population-based study of dementia in 85-year-olds. New Engl J Med; 328:153-158
2. Skoog I. (1996) Sex and Swedish 85-year-olds. New Engl J Med;334:1140-1141
3. Skoog I, Lernfelt B, Landahl S, Palmertz B, Andreasson L-A, Nilsson L, Persson G, Odén A, Svanborg A. (1996) A 15-year longitudinal study on blood pressure and dementia. Lancet;347:1141-1145.
4. Waern M, Beskow J, Runeson B, Skoog I. (1999) Suicidal feelings in the last year of life in elderly people who commit suicide. Lancet;354:917-918
5. Waern M, Beskow J, Runesson B, Skoog I. (1996) High rate of antidepressant treatment in elderly suicides. Brit Med J;313:1118.
6. Waern M, Rubenowitz E, Runeson B, Skoog I, Wilhelmson K, Allebeck P. (2002) Burden of illness and suicide in elderly people: a case-control study. Brit Med J;324:1355-57.
7. Steffens DC, Skoog I, Norton MC, Hart AD, Tschanz JT, Plassman BL, Wyse BW, Welsh-Bohmer KA, Breitner JC. (2000) Prevalence of depression and its treatment in an elderly population: the Cache County study. Arch Gen Psychiatry;57:601-7.
8. Skoog G, Skoog I. (1999) A 40-year follow-up of patients with obsessive-compulsive disorder. Arch Gen Psychiatr;56:121-127.
9. Ostling S, Skoog I. (2002) Psychotic symptoms and paranoid ideation in a nondemented population-based sample of the very old. Arch Gen Psychiatry;59:53-59.
10. Gustafson D, Rothenberg E, Blennow K, Steen B, Skoog I. (2003) An 18-year follow-up of overweight and risk of Alzheimer disease. Arch Intern Med.;163:1524-8
Peer-reviewed publications 2003-2007 (IS)
1. Heijer T, Skoog I, Oudkerk M, de Leeuw FE, de Groot JC, Hofman A, Breteler MM. (2003) Association between blood pressure levels over time and brain atrophy in the elderly. Neurobiol Aging;24:307-13.
2. Gustafson D, Rothenberg E, Blennow K, Steen B, Skoog I. (2003) An 18-year follow-up of overweight and risk of Alzheimer disease. Arch Intern Med.;163:1524-8.
3. Skoog I, Davidsson P, Aevarsson O, Vanderstichele H, Vanmechelen E, Blennow K. (2003) Cerebrospinal Fluid Beta-Amyloid 42 Is Reduced before the Onset of Sporadic Dementia: A Population-Based Study in 85-Year-Olds. Dement Geriatr Cogn Disord;15:169-76
4. Steffens DC, Norton MC, Hart AD, Skoog I, Corcoran C, Breitner JC (2003) Cache County Study Group. Apolipoprotein E genotype and major depression in a community of older adults. The Cache County Study. Psychol Med;33:541-7
5. Gislason TB, Sjogren M, Larsson L, Skoog I. (2003) The prevalence of frontal variant frontotemporal dementia and the frontal lobe syndrome in a population based sample of 85 year olds. J Neurol Neurosurg Psychiatry;74:867-71
6. Guo X, Matousek M, Sonn U, Skoog I, Björkelund C, Steen B. (2003) A longitudinal study on changes of movement performance and their relation to medical conditions in a female population followed from age 70 to 78. Arch Gerontol Geriatr;36:127-140.
7. Lithell H, Hansson L, Skoog I, Elmfeldt D, Hofman A, Olofsson B, Trenkwalder P, Zanchetti A (2003) For the SCOPE Study Group. The Study on Cognition and Prognosis in the Elderly (SCOPE): principal results of a randomized double-blind intervention trial. J Hypertens;21:875-886
8. Erkinjuntti T, Skoog I, Lane R, Andrews C. (2003) Potential long-term effects of rivastigmine on disese progression may be linked to drug effects on vascular changes in Alzheimer brains. Int J Clin Pract;57:756-760.
9. Liebetrau M, Steen B, Skoog I. (2003) Fehler! Textmarke nicht definiert.Stroke in 85-year-olds. Prevalence, incidence, risk factors and relation to mortality and dementia. Stroke;34:2617-2622
10. Östling S, Andreasson L-A, Skoog I. (2003) Psychotic symptoms and basal ganglia calcification in a population-based sample of 85-year-olds. Int J Geriatr Psychiatry.; 18: 983-7.
11. Lernfelt B, Samuelsson O, Skoog I, Landahl S. (2003) Changes in drug treatment in the elderly between 1971 and 2000. Eur J Clin Pharmacol; 59: 637-44.
12. Lissner L, Skoog I, Andersson K, Beckman N, Sundh V, Waern M, Zylberstein DE, Bengtsson C, Bjorkelund C. (2003) Participation bias in longitudinal studies: experience from the Population Study of Women in Gothenburg, Sweden.Scand J Prim Health Care.;21:242-7.
13. Linden T, Skoog I, Fagerberg B, Steen B, Blomstrand C. (2004) Cognitive impairment and dementia 20 months after stroke. Neuroepidemiology; 23:45-52
14. Östling S, Johansson B, Skoog I. (2004) Cognitive test performance in relation to psychotic symptoms and paranoid ideation in non-demented 85-year-olds. Psychol Med;34:443-450
15. Gustafson D, Steen B, Skoog I. (2004) Body mass index and white matter lesions in elderly women. An 18-year longitudinal study. Int Psychogeriatr;16:327-36
16. Tschanz JT, Corcoran C, Skoog I, Khachaturian AS, Herrick J, Hayden KM, Welsh-Bohmer KA, Calvert T, Norton MC, Zandi P, Breitner JC (2004) Cache County Study Group. Dementia: the leading predictor of death in a defined elderly population: the Cache County Study. Neurology.;62:1156-62.
17. Degl'Innocenti A, Elmfeldt D, Hofman A, Lithell H, Olofsson B, Skoog I, Trenkwalder P, Zanchetti A, Wiklund I. (2004) Health-related quality of life during treatment of elderly patients with hypertension: results from the Study on COgnition and Prognosis in the Elderly (SCOPE). J Hum Hypertens.;18:239-45.
18. Liebetrau M, Steen B, Hamann GF, Skoog I. (2004) Silent and symptomatic infarcts on cranial computerized tomography in relation to dementia and mortality. A population-based study in 85-year-olds. Stroke; 35:1816-20
19. Lithell H, Hansson L, Skoog I, Elmfeldt D, Hofman A, Olofsson B, Trenkwalder P, Zanchetti A (2004) For the SCOPE Study Group. The Study on Cognition and Prognosis in the Elderly (SCOPE): outcomes in patients not receiving add-on therapy after randomization. J Hypertens;22:1-8.
20. Gustafson D, Lissner L, Bengtsson C, Björkelund C, Skoog I. (2004) A 24-year follow-up of body mass index and cerebral atrophy. Neurology;63:1876-81.
21. Papademetriou V, Farsang C, Elmfeldt D, Hofman A, Lithell H, Olofsson B, Skoog I, Trenkwalder P, Zanchetti A, for the SCOPE Study Group. (2004) Stroke Prevention with the AT1-receptor Blocker Candesartan in Elderly Patients with Isolated Systolic Hypertension: The Study on COgnition and Prognosis in the Elderly (SCOPE). J Am Coll Cardiol.;44:1175-80
22. Börjesson Hansson A, Edin E, Gislason T, Skoog I. (2004) The prevalence of dementia in 95-year-olds. Neurology.;63:2436-8
23. Braam AW, Delespaul P, Beekman ATF, Deeg DJH, Pérès K, Dewey M, Kivelä S-L, Lawlor BA, Magnusson H, Meller I, Prince MJ, Reischies FM, Roelands M, Saz P, Schoevers RA, Skoog I, Turrina C, Versporen A, Copeland JRM. (2004) National context of healthcare, economy and religion and the association between disability and depressive symptoms in older Europeans: results from the EURODEP concerted action. Eur J Ageing;1:26-36.
24. Copeland JR, Beekman AT, Braam AW, Dewey ME, Delespaul P, Fuhrer R, Hooijer C, Lawlor BA, Kivela SL, Lobo, A, Magnusson H, Mann AH, Meller I, Prince MJ, Reischies F, Roelands M, Skoog I, Turrina C, Devries MW, Wilson KC.. (2004) Depression among older people in Europe: the EURODEP studies. World Psychiatry, 3:45-9
25. Liebetrau M, Hamann GF, Skoog I. (2005) White matter lesions as a risk factor for stroke and dementia. Nervenarzt Jun;76(6):708-15
26. Claesson L., Lindén T, Skoog I, Blomstrand C. (2005) Cognitive impairment after stroke - impact on activities of daily life and costs of care for elderly people. Cerebrovasc Dis;19:102-109.
27. Rosengren A, Skoog I, Gustafson D, Wilhelmsen L. (2005) Body mass index, other cardiovascular risk factors, and hospitalization for dementia. Arch Intern Med;165:321-6.
28. Braam AW, Prince MJ, Beekman ATF, Delespaul P, Dewey ME, Geerlings SW, Kivelä S-L, Lawlor BA, Magnusson H, Meller I, Pérès K, Reischies FM, Roelands M, Schoevers RA, Saz P, Skoog I, Turrina C, Versporen A, Copeland JRM. (2005) Physical health and depressive symptoms in older Europeans: results from EURODEP. Brit J Psychiatry;187:35-42.
29. Lindén T, Samuelsson H, Skoog I, Blomstrand C. (2005) Visual neglect and cognitive impairment in elderly patients late after stroke. Acta Neurol Scand;111:163-8.
30. Mielke MM, Zandi PP, Sjögren M, Gustafson D, Östling S, Steen B, Skoog I. (2005) High total cholesterol levels in late-life associated with a reduced risk of dementia. Neurology;64:1689-95.
31. Skoog I, Lithell H, Hansson L, Elmfeldt D, Hofman A, Olofsson B, Trenkwalder P, Zanchetti A, for the SCOPE Study Group. (2005) Effect of baseline cognitive function on cognitive and cardiovascular outcomes: Study on COgnition and Prognosis in the Elderly (SCOPE) – a randomized double-blind trial. Am J Hypertens.;18:1052-9.
32. Trenkwalder P, Elmfeldt D, Hofman A, Lithell H, Olofsson B, Papademetriou V, Skoog I, Zanchetti A. (2005) The Study on COgnition and Prognosis in the Elderly (SCOPE) - major CV events and stroke in subgroups of patients. Blood Press.;14:31-37.
33. Sacuiu S, Sjogren M, Johansson B, Gustafson D, Skoog I. (2005) Prodromal cognitive signs of dementia in 85-year-olds using four sources of information. Neurology. Dec 27;65(12):1894-900.
34. Björkelund C, Bondyr-Carlsson D, Lapidus L, Lissner L, Mansson J, Skoog I, Bengtsson C. (2005) Sleep Disturbances in Midlife Unrelated to 32-Year Diabetes Incidence: The prospective Population Study of Women in Gothenburg. Diabetes Care 2005;28:2739-44.
35. Mitnitski A, Skoog I, Song X, Waern M, Ostling S, Sundh V, Steen B, Rockwood K. (2006) A vascular risk factor index in relation to mortality and incident dementia. European Journal of Neurology, 13:514-21.
36. Mitnitski A, Song X, Skoog I, Broe GA, Cox JL, Grunfeld E, Rockwood K. (2006) Relative fitness and fraility in elderly men and women in developed countries, in relation to mortality. J Am Ger Soc, 53:2184-2189
37. Norton MC, Skoog I, Franklin LM, Corcoran C, Tschanz JAT, Zandi PP, Breitner JCS, Welsh-Bohmer KA, Steffens DC (2006) for the Cache County Investigators. Gender Differences in the Association between Religious Involvement and Depression: The Cache County (Utah) Study. Journals of Gerontology: Psychological Sciences, 61:129-136.
38. Norton M.C., Skoog I., Toone L., Corcoran C., Tschanz J.T., Lisota R.D., Hart A.D., Zandi P.P., Breitner J.C.S., Welsh-Bohmer, K.A, Steffens, D.C. (2006) Three-year Incidence of First-Onset Depressive Illness in a Population Sample of Older Adults. The Cache County Study. American Journal of Geriatric Psychiatry, 14:237-245.
39. Mielke MM, Zandi PP, Sjögren M, Blennow K, Gustafson D, Sjögren M, Skoog I. (2006) Low serum potassium in mid-life associated with descreased CSF Ab (1-42) in late-life. Alzheimer's Disease and Associated Disorders, 20:30-36.
40. Rockwood K, Mitnitski A, Song X, Steen B, Skoog I. (2006) Long-term risks of death and institutionalisation of elderly people in relation to deficit accumulation at age 70. J Am Ger Soc, 54:975-9..
41. Khachaturian AS, Zandi PP, Lyketsos CG, Hayden KM, Skoog I, Norton MC, Tschanz JT, Mayer LS, Welsh-Bohmer KA, Breitner JCS (2006) for the Cache County Study Group. Anti-Hypertensive Medication Use and Incident Alzheimer's Disease. The Cache County Study. Arch Neurol, 63:686-92
42. Guo X, Sjögren K, Waern Margda, Lissner L, Bengtsson C, Björkelund C, Östling S, Skoog I. (2005) Midlife Lung Function and Incidence of Alzheimer’s disease: a 29-year Longitudinal Study in Women. Neurobiol Aging, 28:343-50.
43. Guo X, Pantoni L, Simoni M, Gustafson D, Bengtsson C, Palmertz B, Skoog I. (2006) Midlife respiratory function related to white matter lesions and lacunar infarcts in late life: The Prospective Population Study of Women in Gothenburg, Sweden. Stroke, 37:1658-62.
44. Henningsson S, Annerbrink K, Olsson M, Allgulander C, Andersch S, Sjödin I, Gustafson D, Skoog I, Norrback K, Adolfsson R, Eriksson E, Westberg L. (2006) The Arg441His polymorphism in the tryptophan hydroxylase 2 gene in Sweden. Am J Med Genet B Neuropsychiatr Genet., 144B:816-817
45. Ostling, S. Pálsson, S. Skoog, I. (2007) The incidence of first-onset psychotic symptoms and paranoid ideation in a representive population sample followed from age 70 to 90 years. Relation to mortality and later development of dementia. Int J Geriatr Psychiatry, 22:520-8
46. Gustafson D, Skoog I, Rosengren L, Zetterberg H, Blennow K. (2007) Ab42 and T-tau in cerebrospinal fluid predict cognitive decline and dementia in a population-based sample Cerebrospinal fluid Ab42 concentration may predict cognitive decline in elderly women. J Neurol Neurosurg Psychiatry, 78:461-4
47. Mitnitski A, Bao L, Skoog I, Rockwood K. (2007) A cross-national study of transitions in deficit counts in two birth cohorts: Implications for modeling ageing. Experimental Gerontology, 42:241-6
48. Linden L, Blomstrand C, Skoog I. (2007) Depressive disorders after 20 months in elderly stroke patients. A case-control study. Stroke, 38:1860-3.
49. Wengreen HJ, Munger RG, Corcoran CD, Zandi P, Hayden KM., Fotuhi M, Skoog I, Norton MC, Tschanz JA, Breitner JCS, Welsh-Bohmer KA. (2007) Antioxidant intake and cognitive function of elderly men and women: The Cache County Study. J Nutr Health Aging, 11:230-7.
50. Simonsen A.H, McGuire J, Podust V.N, Davies H, Minthon L, Skoog I, Andreasen N, Wallin A, Waldemar G, Blennow K. (2007) Identification of a Novel Panel of Cerebrospinal Fluid Biomarkers for Early Stage Alzheimer’s Disease. Neurobiol Aging (in press)
51. Gudmundsson P, Skoog I, Waern M, Blennow K, Palsson S, Gustafson D. (2007) The relationship between cerebrospinal fluid biomarkers and depression in elderly women Am J Ger Psychiatr (in press).
52. Wancata J, Börjesson-Hansson A, Östling S, Sjögren K, Skoog I. (2007) Diagnostic criteria influence dementia prevalence. Am J Geriatr Psychiatry (in press)
53. Börjesson-Hansson A, Gustafson D, Skoog I. (2007) Five-year survival after age 95. Relation to dementia and cognitive function. The Göteborg 95+ Study. Neurology (in press)
54. Östling S, Börjesson-Hansson A, Skoog I. (2007) Psychotic symptoms and Paranoid Ideation in a Population-based sample of 95-year-olds. Am J Geriatr Psychiatry (in press)
55. Gustafson D, Karlsson C, Skoog I, Rosengren L, Lissner L, Blennow K. (2007) Mid-life adiposity factors relate to blood brain barrier integrity in late-life. J Int Med (in press)
56. Guo X, Skoog I, Idrizbegovic E, Pantoni L, Simoni M, Rosenhall U. (2007) Hearing loss and cortical atrophy in a population-based study on non-demented women. Age Ageing (in press)
57. Norton, M.C.,Singh, A., Skoog, I., Corcoran, C., Tschanz, J.T., Zandi, P.P., Breitner, J.C.S., Welsh-Bohmer, K.A., & Steffens, D.C. (2007) Church Attendance and New Episodes of Major Depression in a Community Study of Older Adults. The Cache County Study. Journals of Gerontology: Psychological Sciences (in press).
Books/Invited reviews 2003-2007 (IS)
60. Skoog I. (2003) Highs or lows of blood pressure: a cause of Alzheimer’s disease? Lancet Neurology; 2: 334.
61. Skoog I, Gustafson D. (2003) Hypertension, hypertension-clustering factors and Alzheimer's disease. Neurol Res.;25:675-80