RAJIVGANDHIUNIVERSITY OF HEALTH SCIENCES

BANGALORE, KARNATAKA

ANNEXURE-II

PROFORMA FOR REGISTRATION OF SUBJECT FOR DISSERTATION

1 / NAME OF THE CANDIDATE
ADDRESS / MOHD.AAMIR PASHA
AL-AMEEN COLLEGE OF PHARMACY
HOSUR ROAD, OPP. LAL BAGH MAINGATE. BANGALORE-560 027,
KARNATAKA.
PERMANENT ADDRESS.
MOHD.AAMIR PASHA
C/O MOHD.UMER
AT- KATGHAR,MAQBARA II,
HAZEERA, MORADABAD-244001
UTTAR PRADESH
2 / NAME OF THE INSTITUTION / AL-AMEEN COLLEGE OF PHARMACY
HOSUR ROAD,
BANGALORE - 560027
3 / COURSE OF STUDY AND
SUBJECT / MASTER OF PHARMACY IN
PHARMACEUTICAL MARKETING AND MANAGEMENT
4 / DATE OF ADMISSION / 17/6/2008
5 / TITLE OF THE TOPIC:
“CURRENT TRENDS AND OPPORTUNITIES FOR NUTRACEUTICALS IN INDIAN MARKET”
6 / BRIEF RESUME OF THE INTENDED WORK:
6.1 NEED FOR THE STUDY :
Nutraceuticals enhance the body’s availabilities to withstand the stresses and strains that challenge the health through a changed and impulsive lifestyle.Basic life style discipline and nutrition are few basic requirements for good health.[1]
Nutraceuticals are ingredients with human health benefits beyond basic nutrition, they serve to control the balance between environment stressors and human health, and helps in prevention of certain nutritional deficiency and stress induced diseases.[1]
There are number of products like vitamins, antioxidants, minerals, herbals/botanical, proteins that are classified as nutraceuticals.
The beneficial role of many nutraceuticals may relate to their protective effects against degenerative diseases, such as cardio-vascular disease and cancer. Typically the active ingredients in the supplement is believed to help the body combat metabolic process that lead to degenerative conditions. In this way supplementing the diet with beneficial phytonutrients may reduce the risk of degenerative diseases during aging.[2]
The use of nutraceuticals, as an attempt to accomplish desirable therapeutic outcomes with reduced side effects as compared with other therapeutic agents has met with great monitory success. [3,4]
The global nutraceutical market size currently reaches $110 billion .The projected growth rate is 20% annually. Indian nutraceutical market is currently growing at a faster rate the market size of nutraceutical in India has touched Rs 1,400 to 1,600 crore in the year 2007 and is expected to grow 25% annually, which should be music for growing nutraceutical industries.[1]
Nutraceutical products which have a general health care purpose stand a great opportunity in Indian markets as they have the requisite knowledge and long-tradition which can be transformed in to global outsourcing business.Growing interest in the health benefits of food is a world wide trend that presents opportunities for nutraceuticals business.[5]
The proposed study is aimed at understanding the current trends of the nutraceuticals in Indian market. It will also present the developing areas of nutraceuticals for human health and evaluate factors that will drive the future demand for nutraceuticals in Indian market.
6.2 REVIEW OF LITERATURE
Dr.Stephen De Felice first coined the term neutraceuticals in 1989 As per him these products have nutritional as well as pharmaceutical ingredients which can be consider as food or part of food that provide medical or health benefits including the prevention and treatment of diseases[6].More rigorously, nutraceutical implies that the extract or food is demonstrated to have a physiological benefit or provide protection against a chronic disease.Nutraceuticalproducts nowadays are known as FMHG i.e. fast moving health goods.[7]
Along with the growing healthcare industry in India there is an emerging trend in ‘Fast Moving Healthcare Goods (FMHG) in India; worldwide known as nutraceuticals, whichare by definition, ingredients with human health benefits beyond basic nutrition.[8]
According to Cygnus estimates, nutraceuticals market in 2007was INR18.75 billion and expected to grow at 20% CAGR to achieve a market size ofINR27 billion in 2009. Global nutraceuticals market is estimated at USD120 billion in2007 growing at 7% (CAGR). The US has been the major market for nutraceuticals withIndia and China becoming fastest growing markets. Nutraceuticals are gainingacceptance for their ability to address several diseases. Vitamins, Minerals and Nutrientsconstitute about 85% of the market while antioxidants and anti-agents account for 10%other segments such as herbal extracts occupy 5% of the market, globally.[8]
Indian nutraceutical market is growing at very fast rate, but India is having more prescription market when compared to OTC market. Indian nutraceutical market as OTC market is in infant stage but growing at very fast rate[8]. Nutraceutical is one huge business opportunity awaiting the Indian pharmaceutical industry in the coming years. At least a dozen large companies currently produce and market neutraceuticals today.[9]
Some of the major market players in the nutraceutical field are Novartis, Sami lab, Parry Nutraceutical, Abott lab, GSK, Zydus, British Biologicals, Raptakos.
Various products that are classified as nutraceuticals are vitamins, anti-oxidants, minerals, herbals, proteins and fibers.[8]
Antioxidants are nutraceuticals whose deficiency states are associated with numerous dreaded disease conditions .viz., cardio-vascular disease, Diabetes, Rheumatoid arthritis, Alzheimer’s disease. Some of the nutraceuticals classified as antioxidants are vitamin C and vitamin E, carotenoids (beta carotene & Lycopene), thiols, minerals etc.[10]
Minerals are micro nutrients that plays a significant role in strengthening the bones and keeping heart, skin and other body parts healthy. There are different types of mineral supplements such as calcium, potassium, magnesium, zinc, iron, copper, selenium, boron and chromium, which when taken in appropriate quantity will help in preventing and treating serious disorders.
Number of products that are derived from natural herbs and plant derivatives are consumed to promote good health. Some plant metabolites that are recognized for use in nutraceuticals are as follows:-
Flavanoids: Flavanoids are a broad category of compounds produced by plants and many appear to have nutraceutical potential by lowering blood chlosterol level, osteoporotic and Carcinogenic properties.[11]
Proteinase and alpha amylase inhibitors:Some plant products are protease and proteinase inhibitors.Tomatoes, legumes and other plant components produce these substances and is believed to have anti-carcinogenic properties.[12]
Policosanols: Extracted form plant waxes are widely used by nutraceutical manufacturers for cholesterol management.[13]
Several other cholesterol lowering nutraceuticals include black tea extracts, novel soy protein fractions, polymethoxylated flavones (PMFs)
Polymethoxylated Flavones are abundant phytochemicals found in citrus that are now commercially available in the dietary supplements as extracts.They have shown impressive anti-cholesterolemic activity.[13]
Banaba (lagerstroemia speciosa): It contains two important constituents corosolic acid
and ellagitannins which seem to have an insulin like effect and also activate insulin
receptor.
Gymnema (gymnema sylvestre):It acts as hypoglycemic agent in combination with
insulin.[14]
The ongoing research will lead to a new generation of food, which will certainly cause the interface between food and drug to become increasingly permeable. The present accumulated knowledge about nutraceuticals represents undoubtedly a great challenge for nutritionists, physicians, food technologists and food chemists.
Public health authorities consider prevention and treatment with nutraceuticals as a powerful investment in maintaining health and to act against nutritionally induced acute and chronic diseases, thereby promoting optimal health and quality of life.[15]
6.3:OBJECTIVES OF THE STUDY:-
  • Usefulness of nutraceuticals for treatment of different diseases states.
  • Nutraceutical formulation /products available currently in the market for treatment /Management of different physiological disturbances.
  • To get an insight into research studies resulting from the convergence of food supplements and pharmaceuticals.
  • Study the newer trends of nutraceuticals in Indian market with respect to selected disease conditions.
  • Estimate the current opportunities for nutraceuticals in Indian market.

7 / MATERIALS AND METHODS:
7.1 SOURCE OF DATA:
a) Primary source:- Primary data will be obtained by administering questionnaires to
Doctors:
Inclusion criteria: Specialities of doctors include general practitioners,consultant physicians, cardiologists, diabetologists and ayurvedic specialists.
Exclusion criteria: Doctors who are specialized in any other discipline other than those
specified will be excluded form the survey.
Chemists :
Inclusion criteria:-allopathic and ayurvedic retail medical shops and wholesale shops.
Exclusion criteria:-homeopathic retail medical shops.
b) Secondary source
The related information would be obtained from:-
  • Internet
  • Nutraceutical journals
  • Pharma pulse
  • Pharma biz
  • Text books on nutraceuticals
7.2Method of collection of data:
  1. Preliminary communication with doctors and Chemists
  1. Sampling technique : Convenience sampling
  1. Sample size : 150
a)Doctors : 100
b)Chemists : 50
.
7.3 Does the study require any investigation or interventions to be conducted on patients or other humans or animals ?
Doctors, Chemists from the respective healthcare fields will be interviewed; hence prior permission will be sought.
7.4 Has ethical clearance been obtained from your institution?
Applied for ethical clearance.
8.0 / LIST OF REFERENCES :
3. Nelson NJ.Purple carrots, margarine laced with wood pulp? Nutraceuticals move into
Supermarket .J Natl Cancer Ins.1999; 91: 755-757
4. Whitman M. understanding the perceived need for complementary and alternative
nutraceuticals :life style issues. Clin J oncol Nurs.2001;5: 190-194
5.
6. 07ilp76.pdf
7. Health Canada; Policy paper on nutraceuticals/functional foods and health claims on
Foods,2002
8.
9.
10. Kusum.Devi.V, Fazlu.R “Nutraceutical antioxidants”-An overview,Indian J.
Pharm.Educ.36(1)Jan-mar 2002.
11. Vance ,C.P and Griffith, S.M., The molecular biology of N metabolism , in plant
Physiology. Biochemistery and molecular biology, 1990
12. Taiz, L. and Zeiger , E., plant defenses in plant physiology, 2nd e.d., Sinaver associates,
Inc.,Sunderland. MA,1998
  1. http//:findarticle.com/p/articles/mi_hb223/is_/ai_n29191763
  2. http//:
15. http//:
9. / Signature of the candidate:
10. / Remarks of the Guide: / Recommended for approval
11. / Name and Designation of:
11.1. Institutional Guide: / Dr.V.Kusum Devi
Professor,Dept. of pharmaceutical
Marketing and Management
AL-Ameen College of Pharmacy
Hosur road, Bangalore-560 027
11.2. Signature:
11.3. Co-Guide / Ganesh N. Achar
Product manager
British Biologicals
No. 30, Ashoka pillar Road,2ndBlock Jayanagar, Bangalore-560 011
11.4. Signature:
11.5. Head of the Department: / Dr.V.Kusum Devi
Professor,Dept. of pharmaceutical
Marketing and Management
AL-Ameen College of Pharmacy
Hosur road, Bangalore-560 027
11.6. Signature
12. / 12.1. Remarks of the Principal / Forwarded to the University
12.2. Signature /
Prof. B. G. SHIVANANDA
Principal
Al Ameen College of Pharmacy
Hosur Road, Bangalore – 560 027.

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