Scientific Programs-July 4 (Thu)
PLENARY LECTURE
Plenary Lecture 6
08:30 ~ 09:20, Convention Hall (B1)
Sponsored by Korea Research Foundation
08:30 SACCHAROMYCES CEREVISIAE: GENETICS AND
BREEDING
Yasuji Oshima, Kansai Univ., Japan
SYMPOSIA
Symposium 13: Genetics of Filamentous Fungi
10:00 ~ 12:30, Convention Hall A (B1)
Chairperson: Michael J. Hynes, Univ. of Melbourne, Australia
Sponsored by Kook Soon Dang
10:00 ASPERGILLUS GENETICS: WHAT HAPPENED TO
THE ONE GENE ONE ENZYME IDEA?
Rolf Prade, Oklahoma State Univ., USA
10:25 Regulation of the amylolytic genes in Aspergilli
Norihiro Tsukagoshi, Nagoya Univ., Japan
10:50 CONTROL OF CATABOLISM OF NITROGEN AND
CARBON SOURCES IN Aspergillus NIDULANS
Michael J. Hynes, Univ. of Melbourne, Australia
11:15 PROTEIN COMPLEXES CONTAINING MULTIPLE
REGULATORY FACTORS CONTROL THE EXPRESSION OF
THE PENICILLIN BIOSYNTHESIS GENES IN PENICILLIUM
CHRYSOGENUM
Juan F. Martin, Univ. of Leon, Spain
11:40 SIGNALING MECHANISMS OF GROWTH AND
DEVELOPMENT IN FILAMENTOUS FUNGI
Jaehyuk Yu, The Univ. of Wisconsin-Madison, USA
12:05 GENETIC CONTROL OF SEXUAL DEVELOPMENT IN
ASPERGILLUS NIDULANS
Dong-Min Han, Wonkwang Univ., Korea
Symposium 14: Plant-Microbe Interaction
10:00 ~ 12:30, Convention Hall B (B1)
Chairperson: Ralph Dean, NC State Univ., USA
Sponsored by Korea Science and Engineering Foundation
10:00 THE MAGNAPORTHE GRISEA GENOME PROJECT
Ralph Dean, NC State Univ., USA
10:30 The genome sequence of Xanthomonas
oryzae pv. oryzae KACC10331, bacterial blight on
rice
Dong-Suk Park, National Institute of Agricultural Biotechnology,
RDA, Korea
11:00 SIGNAL TRANSDUCTION DURING PHYTOPATHOGENIC
FUNGAL DEVELOPMENT
Martin B. Dickman, Univ. of Nebraska, USA
11:30 SIGNAL TRANSDUCTION PATHWAYS REGULATING
FUNGAL PATHOGENESIS IN COLLETOTRICHUM
LAGENARIUM
Yoshitaka Takano, Kyoto Univ., Japan
12:00 SOME GALL!, THE GENETICS OF THE CORN SMUT DISEASE
INTERACTION
Scott E. Gold, Univ. of Georgia, USA
Symposium 15: Industrial Application of Viruses
10:00 ~ 12:30, Convention Hall C (B1)
Chairperson: Gerhard Hunsmann, German Primate Centre, Germany
Sponsored by Korea Vaccine Co., Ltd.
10:00 RETROVIRAL VECTORS FOR GENE THERAPY
Gerhard Hunsmann, German Primate Centre, Germany
10:25 Rational Design of HIV Vaccines
Xiao Fang Yu, Johns Hopkins Univ., USA
10:50 RECOMBINANT ALPHAVIRUS REPLICONS FOR
HETEROLOGOUS GENE DELIVERY AND EXPRESSION
Gunilla B. Karlsson, Karolinska Institute, Sweden
11:15 ADENOVIRUS AS A GENE DELIVERY SYSTEM
Dong-Soo Im, Korea Research Institute of Bioscience and
Biotechnology, Korea
11:40 AAV (ADENO-ASSOCIATED VIRUS) VECTOR AND ITS
APPLICATION TO GENE THERAPY
Keiza Ozawa, Jichi Medical School, Japan
12:05 Recombinant Poliovirus Sabin 1 as a Safe and
Effective Mucosal Vaccine Vector
Yong-Soo Bae, Hannam Univ., Korea
Symposium 16:
New Approaches to Genomics and Functional Genomics
10:00 ~ 12:30, Sapphire Room (2F)
Chairperson: John Heidelberg, TIGR, USA
Sponsored by Macrogen
10:00 THE INS AND OUTS OF MEMBRANE TRANSPORTERS- A
GENOMIC VIEW
Ian. T. Paulsen, The Institute for Genomic Research, USA
10:30 METABOLOMICS AND GENETIC PROGRAMMING: A NOVEL
APPROACH TO FUNCTINOAL GENOMICS, WITH HIGH
EXPLANATORY POWER
Douglas Kell, Univ. of Aberystwyth, UK
11:00 GENOME-DRIVEN FUNCTIONAL RECONSTRUCTION
OF PRODUCING MICROORGANISMS AS A FOUNDATION
FOR RATIONAL STRAIN DESIGN
Michael Fonstein, Intergrated Genomics, Inc., USA
11:30 GENESIS OF ARTIFICIAL STRAINS BASED ON MICROBIAL
FUNCTIONAL GENOMICS
Sun Chang Kim, Korea Advanced Institute of Science and
Technology, Korea
12:00 EXPLORING GENOMIC POTENTIAL AND MICROBIAL
DIVERSITY OF NONCULTURABLE MICROORGANISMS
John Heidelberg, The Institute for Genomic Research, USA
Symposium 17: Biosynthesis and Degradation of Polymers
14:00 ~ 16:30, Convention Hall A (B1)
Chairperson: Alexander Steinbüchel, Univ. of Münster, Germany
Sponsored by KOMED Co., Ltd.
14:00 BIOSYNTHESIS AND PERSPECTIVES FOR THE
BIOTECHNOLOGICAL PRODUCTION OF THE
CYANOBACTERIAL POLYAMIDE CYANOPHYCIN
Fred Bernd Oppermann-Sanio, Univ. of Muenster, Germany
14:30 BIOSYNTHESIS OF POLYHYDROXYALKANOIC ACIDS AND
ENGINEERING OF METABOLIC PATHWAYS TOWARDS
NOVEL ROUTES AND POLYESTERS
Alexander Steinbüchel, Univ. of Münster, Germany
15:00 BIODEGRADATION OF POLYHYDROXYALKANOATES
BY SPECIFIC AND UNSPECIFIC ENZYMES
Yoshiharu Doi, RIKEN Institute, Japan
15:30 Oxidative Enzymes of Biotechnological
Interest Capable of Depolymerizing Lignin
Martin Hofrichter, International Graduate School Zittau,
Germany
16:00 Molecular action of microbial proteins
targeting and degrading chitinous substrates
Hildgung Schrempf, Univ. of Osnabruck, Germany
Symposium 18: Genetics of Bacilli
14:00 ~ 17:00, Convention Hall B (B1)
Chairperson: Dusko Ehrlich, INRA, France
Sponsored by LOTTE Chilsung Beverage Co, Ltd.
14:00 ASPECTS OF GENETICS AND ETHICS
Jens T. Andersen, Novozymes A/S, Denmark
14:25 DNA ARRAY ANALYSIS OF BACILLUS SUBTILIS
PLEIOTROPIC MUTATIONS AFFECTING SPORULATION AND
ENZYME PRODUCTION
Eugenio Ferrari, Genencor International Inc., USA
14:50 IDENTIFICATION OF A GENE SET ESSENTIAL FOR THE
Bacillus SUBTILIS GROWTH
Naotake Ogasawara, Nara Institute of Science and Technology,
Japan
15:15 DNA REPLICATION IN BACILLUS SUBTILIS
Dusko Ehrlich, Institut National de la Recherche Agronomique,
France
15:40 FROM GENE REGULATION TO GENE FUNCTION:
REGULATORY NETWORKS IN BACILLUS SUBTILIS
Colin R. Harwood, Newcastle Univ., UK
16:05 FUNCTIONAL GENOMICS OF PROTEIN SECRETION BY THE
BACILLUS CELL FACTORY
Jan Maarten van Dijl, Univ. of Groningen, Netherlands
16:30 GENOME SEQUENCING AND ANALYSIS OF PAENIBACILLUS
POLYMYXA E681, A PLANT-PROBIOTIC BACTERIUM
Seung-Hwan Park, Korea Research Institute of Bioscience and
Biotechnology, Korea
Symposium 19: Genetics of Extremophiles
14:00 ~ 16:30, Convention Hall C (B1)
Chairperson: Tairo Oshima, Tokyo Univ. of Pharmacy and Life Science, Japan
Garabed Antranikian, Technical Univ. Hamburg-Harburg Germany
Sponsored by Bioproducts Reseach Center, Yonsei Univ. and
Korea Research Institute of Bioscience and Biotechnology
14:00 BIOTECHNOLOGY OF EXTREMOPHILES: SPOTLIGHT ON A
RAPIDLY MOVING FIELD
Garabed Antranikian, Technical Univ. Hamburg-Harburg,
Germany
14:25 RECENT ADVANCES IN GENETICS OF
HYPERTHERMOPHILIC ARCHAEA
Mose Rossi, CNR, Italy
14:50 WHOLE GENOME SEQUENCE OF BACILLUS HALODURANS
C-125 WITH AN EYE TO BIOTECHNOLOGICAL
APPLICATIONS
Koki Horikoshi, JAMSTEC, Japan
15:15 THE STRUCTURAL AND FUNCTIONAL WHOLE-CELL
PROJECT OF THERMUS THERMOPHILUS HB8
Seiki Kuramitsu, Osaka Univ., Japan
15:40 SUGAR TRANSPORT IN HYPERTHERMOPHILIC ARCHAEA
Arnold J. M. Driessen, Univ. of Groningen, the Netherlands
16:05 GENOMIC AND BIOCHEMICAL ANALYSIS OF HYDROGEN
PRODUCTION BY THERMOPHILES
Frank T. Robb, Univ. of Maryland, USA
Symposium 20: Heterologous Expression Systems
14:00 ~ 16:55, Sapphire Room (2F)
Chairperson: Cornelis Hollenberg, Univ. of Duesseldorf, Germany
Sponsored by the Center for Functional Analysis of Human Genome amd
Korea Research Institute of Bioscience and Biotechnology (KRIBB)
14:00 OVERVIEW OF HETEROLOGOUS EXPRESSION SYSTEMS
Cornelis Hollenberg, Univ. of Duesseldorf, Germany
14:25 Determining mammalian gene function by
transcriptional profiling in yeast
David Y. Thomas, McGill Univ., USA
14:50 PROTEOLYTIC CLEAVAGE OF HETEROLOGOUS PEPTIDES
SECRETED IN YEASTS BY ENDOPROTEASES OF THE YAPSIN
FAMILY
Hyun Ah Kang, KRIBB, Korea
15:15 ENGINEERING OF PROTEIN GLYCOSYLATION TO PRODUCE
THERAPEUTIC GLYCOPROTEINS AND NOVEL
OLIGOSACCHARIDES IN SACCHAROMYCES CEREVISIAE
Yoshifumi Jigami, National Institute of Advanced Industrial
Science and Technology, Japan
15:40 RECENT ADVANCES IN FOREIGN PROTEIN EXPRESSION
USING YARROWIA LIPOLYTICA.
Claude Gaillardin, Institut National Agronomique Paris-Grignon,
France
16:05 NEW APPROACHES AND SUCCESSES FOR THE
PRODUCTION OF HETEROLOGOUS PROTEINS WITH
FILAMENTOUS FUNGI
Cees A.M.J.J. van den Hondel, TNO Nutrition and Food Research
and Univ. of Leiden, The Netherlands
16:30 MODULAR COMPONENTS FOR TUNING UP EFFICIENT
PRODUCTION OF RECOMBINANT PROTEINS IN
ESCHERICHIA COLI
Ralf Mattes, Univ. of Stuttgart, Germany
Poster Session C (P1~8)
P1. Genetics of Clostridia
13:00 ~ 14:00, Diamond Hall (B1)
P1-01 EXPRESSION OF AN ABC TRANPORTER FOR PHOSPHATE IN
CLOSTRIDIUM ACETOBUTYLICUM DURING ACID AND
SOLVENT FORMATION
Hubert Bahl (Univ. of Rostock, Germany), Ralf-Joerg Fischer,
Uta Meyer, Sonja Oemcke, Maren Mix
P1-02 EXPRESSION OF BOTULINUM NEUROTOXIN LIGHT CHAIN
IN E. COLI STRAIN OVEREXPRESSING ARG-TRNA (ARGD)
AND ILE-TRNA(ILEX)
Soon-Yong Choi (Hannam Univ., Korea), Hye Young Seong,
Moon Hee Lee, Jin Sook Kim
P2. Genetics of Actinomycetes
13:00 ~ 14:00, Diamond Hall (B1)
P2-01 GLYCOGEN AND TREHALOSE METABOLISM IN
TREPTOMYCES COELICOLOR
Jesse Alderson (John Innes Centre, UK), Celia J. Bruton,
Marcus Yeo, Keith F. Chater
P2-02 CLONING AND CHARACTERIZATION OF ESPERAMICIN
GENE CLUSTER FROM ACTINOMADURA VERRUCOSOSPORA
Devi Bahadur Basnet (SunMoon Univ., Korea), Tae-jin Oh,
Hei Chan Lee, Kwangkyoung Liou, Jae Kyung Sohng
P2-03 FACTOR C, A SECRETED PLEIOTROPIC AUTOREGULATOR
OF CELL DIFFERENTIATION IN STREPTOMYCES GRISEUS
S. Biro (Univ. of Debrecen, Hungary), Z. Birko, Z. Kiss, U. Keller
P2-04 THE FATTY ACID BIOSYNTHESIS OPERON IN THE CDA
CLUSTER
Matthew Borg (UMIST, UK), Jason Micklefield, Colin P. Smith
P2-05 A NOVEL 4-ALPHA-GLUCANOTRANSFERASE OF
STREPTOMYCES COELICOLOR A3(2)
Celia Bruton (John Innes Centre, UK), Keith Chater
P2-06 FUNTIONAL ANALYSIS OF THE GENES ENCODING
PROTEAES IN STREPTOMYCES GRISEUS
Won-Jae Chi (Myongji Univ., Korea), Si-Sun Choi, Yun-Hee Kim,
Eun Young Choi, Chang-Goo Hyun, Soon-Kwang Hong
P2-07 EXPRESSION AND PROTEOLYTIC MODIFICATION OF
PROTEASE INHIBITOR (SFI) FROM STREPTOMYCES
FRADIAE SMF9
Sungjin Choi (Seoul National Univ., Korea), Hyoung Tae Kim,
Kye Joon Lee
P2-08 STUDIES ON THE SUGAR RELATED BIOSYNTHESIS GENE
CLUSTER FROM STREPTOMYCES TENEBRARIUS H6
Yu Du (CAMS, China), Yiguang Wang, Yiguang Wang
P2-09 AN STATIONARY PHASE ACYL-COA SYNTHETASE OF
STREPTOMYCES COELICOLOR A3(2) IS NECESSARY FOR THE
NORMAL ONSET OF ANTIBIOTIC PRODUCTION
H. Gramajo (Universidad Nacional de Rosario, Argentina), C.
Banchio
P2-10 PCR TARGETING IN STREPTOMYCES AND ITS USE TO
IDENTIFY THE GENE FOR THE "DAMP SOIL" ODOUR,
GEOSMIN
Bertolt Gust (John Innes Centre, UK), Greg Challis,
Kay Fowler, Tobias Kieser, Keith Chater
P2-11 THE SC6E10.21C REGION UPSTREAM OF THE GLK(A) GENE,
RESTORES GLUCOSE UPTAKE-GLK ACTIVITY IN MUTANT
STRAINS OF STREPTOMYCES PEUCETIUS VAR. CAESIUS,
INSENSITIVE TO CARBON CATABOLITE REPRESSION
Silvia Guzman (Univ. of Mexico, Mexico), Sergio Sanchez,
Elizabeth Langley
P2-12 NOVEL VANCOMYCIN RESISTANCE GENE CLUSTER IN
STREPTOMYCES COELICOLOR
Hee-Jeon Hong (John Innes Centre, UK), Matt Huchings,
Mark Buttner
P2-13 ISOLATION AND FUNCTIONAL ANALYSIS OF THE
BIOSYNTHETIC GENE CLUSTER OF THE
MANNOPEPTIMYCIN GLYCOPEPTIDE ANTIBIOTIC
COMPLEX
John Hucul (Wyeth Research, USA), Michael Greenstein,
Nathan Magarvey
P2-14 CELL SURFACE HYDROPHOBICITY OF STREPTOMYCES SP.
9612
Kwang-Soon Hyun (KORDI, Korea), Kyu-Jin Park,
Kyung Hee Cho, Hong Kum Lee
P2-15 THE EFFECTS OF DNA BINDING BY S. COELICOLOR
PARTITIONING PROTEIN PARB
Dagmara Jakimowicz (John Innes Centre, UK), Jolanta
Zakrzewska-Czerwinska, Keith F. Chater
P2-16 MUTATIONAL ANALYSIS OF S. COELICOLOR CDA
MUTANTS REVEALS MODULAR AMPLIFICATIONS IN THE
CALCIUM DEPENDENT ANTIBIOTIC (CDA) PEPTIDE
SYNTHETASE 1 GENE
John Jim (UMIST, UK), Fiona Flett, Colin Smith
P2-17 STRINGENT RESPONSES CHARACTERS OF ANTIBIOTIC
SYNTHESIS IN S. CLAVULIGERUS
Wook Jin (Seoul National Univ., Korea), Kye Joon Lee
P2-18 ISOLATION AND FUNCTIONAL ANALYSIS OF
SPECTINOMYCIN BIOSYNTHETIC GENES
Y. Y. Jo (Myong Ji Univ., Korea), S. H. Kim, Y. Y. Yang, J. W. Suh,
R. D. Park
P2-19 ISOLATION AND FUNCTIONAL ANALYSIS OF
BLUENSOMYCIN RESISTANCE GENES IN STREPTOMYCES
BLUENSIS
Y. G. Jung (Myong Ji Univ., Korea), J. S. Shim, H. S. Park,
C. M. Kang, Y. Y. Yang, J. W. Suh
P2-20 STREPTOMYCES MUTANTS AND PROTOPLAST
REGENERATION AS A TOOL FOR THE PLANT PATHOGENIC
FUNGI BIOCONTROL
Kamal Khalil (National Research Center, Egypt)
P2-21 CONSTITUTIVE OVEREXPRESSION OF
S-ADENOSYLMETHIONINE SYNTHETASE IN
STREPTOMYCES LIVIDANS TK-23 LEADS TO
ACCUMULATION OF ACTINORHODIN
D. J. Kim (Myong Ji Univ., Korea), J. H. Huh, Y. Y. Yang,
C. M. Kang, I. H. Lee, C. G. Hyun, S. Y. Oh, S. K. Hong, J. W. Suh
P2-22 PHYSIOLOGICAL ROLE OF ß-LACTAMASE INHIBITORY
PROTEINS IN STREPTOMYCES EXFOLIATUS SMF19
Dae Wi Kim (Seoul National Univ., Korea), Chang Hyun Jin,
Eun ji Kho, Hyun Sook Lee, Sung Gyun Kang, Kye Joon Lee
P2-23 THE CLONING AND FUNCTIONAL ANALYSIS OF O-
CARBAMOYLTRANSFERASE GENE FROM STREPTOMYCES
BLUENSIS
H. N. Kim (Myong Ji Univ., Korea), Y.G Jung, Y. Y. Yang,
J. W. Suh
P2-24 CLONING OF THE GENE ENCODING Γ-BUTYROLACTONE
AUTOREGULATOR RECEPTOR PROTEIN FROM
STREPTOMYCES CLAVULIGERUS
H. S. Kim (Keimyung Univ., Korea), Y. J. Lee, C. K. Lee, Y. I.
Hwang, I. S. Lee, T. S. Yu, T. Nihira
P2-25 Novel Thermophilic Streptomyces that produce
peroxidases and polyphenol oxidases
Ralph Kirby (Rhodes Univ., South Africa), Chido Mhlanga,
Stephanie Burton
P2-26 ANALYSIS OF GENETIC DIVERSITY OF ACTINOMYCETES
INSIDE LIME CAVES BY PCR-RAPD AND DGGE METHOD
J. L. Kwon (KRIBB, Korea), J. M. Lim, S. M. Lee, D. J. Park,
J. C. Lee, C. J. Kim
P2-27 THE ROLE OF EXTRACELLULAR PROTEASES IN
DIFFERENTIATION OF STREPTOMYCES EXFOLIATUS SMF13
Dae Hoon Lee (Seoul National Univ., Korea), Youn-hoa Kim, In
Seop Kim, Kye Joon Lee
P2-28 EXPRESSION OF SPCS2 AND SPCB BIOSYNTHETIC GENES IN
SPECTINOMYCIN AND VERIFICATION OF BIOSYNTHETIC
PROCESS
Jihun Lee (SunMoon Univ., Korea), Tek Narayan Lamichhane,
Kwang-Kyoung Liou, Hei-Chan Lee, Jae-Kyung Sohng
P2-29 CHITINASE-PRODUCING MARINE BACTERIA FROM CHEJU
ISLAND
Yoo Kyung Lee (KORDI, Korea), Kyeung Hee Cho, Jae Hak Sohn,
Hong Kum Lee
P2-30 ENHANCED EXPRESSION OF S-ADENOSYLMETHIONINE
SYNTHETASE CAUSES OVERPRODUCTION OF
ACTINORHODIN IN STREPTOMYCES COELICOLOR A3(2)
A. Lezhava (National Food Research Institute, Japan), T. Hosaka,
S. Okamoto, Y. Okamoto-Hosoya, K. Ochi
P2-31 CLONING AND SEQUENCING OF TYPE I POLYKETIDE
SYNTHASE GENE CLUSTER HOMOLOGUE IN
STREPTOMYCES SP. GERI-155, A PRODUCER OF MACROLIDE
ANTIBIOTIC GERI-155
Si Kyu Lim (Yeungnam Univ., Korea), Jae Kyung Sohng,
Jin Cheol Yoo, Won Gon Kim, Ick Dong Yoo, Doo Hyun Nam
P2-32 CLONING AND CHARACTERIZATION OF THE
BIOSYNTHETIC GENE CLUSTER FOR THE ANTITUMOR
CHROMOMYCIN A3 FROM Streptomyces griseus subsp.
griseus
Nuria Menendez (Univ. of Leon, Spain), Alfredo F. Brana,
Jose A. Salas, Carmen Mendez
P2-33 IDENTIFICATION AND CHARACTERIZATION OF GENES
INVOLVED IN BIOSYNTHESIS OF GENTAMYCIN
Young-Ho Moon (Genotech Corp. Korea), Jae-Jong Kim,
Dong-Hwan Kim, Kang-Ryul Choi, Hae-Young Jeong,
Jin Suk Woo, Joo Ho Lee, Madan Kumar Kharel, Hei Chan Lee,
Kwangkyoung Liou
P2-34 DNA-DEPENDENT RNA POLYMERASE IN STREPTOMYCETES
- THE ALPHA SUBUNIT MODIFICATION DURING THE LIFE
CYCLE
Lucie Najmanova (Academy of Sciences of the Czech Republic),
Jiri Janata, Petr Novak, Frank Kalousek, Jaroslav Spizek
P2-35 CHARACTERISATION AND MANIPULATION OF THE NON-
RIBOSOMAL PEPTIDE SYNTHETASE ENZYMES INVOLVED IN
CDA BIOSYNTHESIS
J.M. Neary (UMIST, UK), C. Milne, J. Micklefield, C.P. Smith
P2-36 A BIOSYNTHETIC GENE FOR GAMMA-BUTYROLACTONE
AUTOREGULATORS FROM
T. Nihira (Osaka Univ., Japan), N. Shikura, J. Yamamura
P2-37 CLONING AND SEQUENCING OF THE THIENAMYCIN
BIOSYNTHETIC GENE CLUSTER FROM THE PRODUCER