Supplemental Table III. Kegg pathways with low representation in the up-regulated dataset. Only pathways containing less than four genes are listed (grouped as “other” in Fig. 2).

Kegg assignment / Pathways / UP (%) / Genes symbol
rno04540 / Gap junction / 1.8 / Gnas;Htr2a;Adcy5
rno00480 / Glutathione metabolism / 1.8 / Oplah;Idh1;Gstt1
rno04910 / Insulin signaling pathway / 1.8 / Akt2;Pygl;Irs3
rno05212 / Pancreatic cancer / 1.8 / Jak2;Cdkn2a;Akt2
rno03010 / Ribosome / 1.8 / Rpl15;Uba52;Rps11
rno04530 / Tight junction / 1.8 / Akt2;Actn4;Cldn11
rno04620 / Toll-like receptor signaling pathway / 1.8 / Map2k6;Akt2;Cd14
rno00270 / Cysteine and methionine metabolism / 1.2 / Mat1a;Sult4a
rno04512 / ECM-receptor interaction / 1.2 / Itga6;Col1a2
rno00071 / Fatty acid metabolism / 1.2 / Acadm;Cpt2
rno05214 / Glioma / 1.2 / Cdkn2a;Akt2
rno04630 / Jak-STAT signaling pathway / 1.2 / Jak2;Akt2
rno04670 / Leukocyte transendothelial migration / 1.2 / Actn4;Cldn11
rno00591 / Linoleic acid metabolism / 1.2 / Alox5;Cyp2c
rno04916 / Melanogenesis / 1.2 / Gnas;Adcy5
rno00860 / Porphyrin and chlorophyll metabolism / 1.2 / Ugt1a6;Blvra
rno03320 / PPAR signaling pathway / 1.2 / Acadm;Cpt2
rno00500 / Starch and sucrose metabolism / 1.2 / Ugt1a6;Pygl
rno04660 / T cell receptor signaling pathway / 1.2 / Cd8a;Akt2
rno04520 / Adherens junction / 0.6 / Actn4
rno00150 / Androgen and estrogen metabolism / 0.6 / Ugt1a6
rno04612 / Antigen processing and presentation / 0.6 / Cd8a
rno04210 / Apoptosis / 0.6 / Akt2
rno04662 / B cell receptor signaling pathway / 0.6 / Akt2
rno00410 / beta-Alanine metabolism / 0.6 / Acadm
rno05219 / Bladder cancer / 0.6 / Cdkn2a
rno00650 / Butanoate metabolism / 0.6 / Aldh5a1
rno00930 / Caprolactam degradation / 0.6 / Akr1a1
rno04110 / Cell cycle / 0.6 / Cdkn2a
rno00532 / Chondroitin sulfate biosynthesis / 0.6 / Xylt2
rno00020 / Citrate cycle (TCA cycle) / 0.6 / Idh1
rno05210 / Colorectal cancer / 0.6 / Akt2
rno04060 / Cytokine-cytokine receptor interaction / 0.6 / Csf1
rno05213 / Endometrial cancer / 0.6 / Akt2
rno04012 / ErbB signaling pathway / 0.6 / Akt2
rno00565 / Ether lipid metabolism / 0.6 / Pld2
rno00251 / Glutamate metabolism / 0.6 / Aldh5a1
rno01031 / Glycan structures - biosynthesis I / 0.6 / Xylt2
rno01030 / Glycan structures - degradation / 0.6 / Hyal2
rno00561 / Glycerolipid metabolism / 0.6 / Akr1a1
rno00564 / Glycerophospholipid metabolism / 0.6 / Pld2
rno00010 / Glycolysis / Gluconeogenesis / 0.6 / Akr1a1
rno00531 / Glycosaminoglycan degradation / 0.6 / Hyal2
rno05016 / Huntington's disease / 0.6 / Cltc
rno04950 / Maturity onset diabetes of the young / 0.6 / Pax6
rno04150 / mTOR signaling pathway / 0.6 / Akt2
rno04650 / Natural killer cell mediated cytotoxicity / 0.6 / Gzmb
rno04330 / Notch signaling pathway / 0.6 / Jag2
rno04115 / p53 signaling pathway / 0.6 / Cdkn2a
rno00040 / Pentose and glucuronate interconversions / 0.6 / Ugt1a6
rno00640 / Propanoate metabolism / 0.6 / Acadm
rno00240 / Pyrimidine metabolism / 0.6 / Dck
rno00720 / Reductive carboxylate cycle (CO2 fixation) / 0.6 / Idh1
rno00450 / Selenoamino acid metabolism / 0.6 / Mat1a
rno04130 / SNARE interactions in vesicular transport / 0.6 / Gosr2
rno04742 / Taste transduction / 0.6 / Gnas
rno04350 / TGF-beta signaling pathway / 0.6 / Dcn
rno00380 / Tryptophan metabolism / 0.6 / Acmsd
rno04120 / Ubiquitin mediated proteolysis / 0.6 / Cul5
rno00280 / Valine. leucine and isoleucine degradation / 0.6 / Acadm
rno04370 / VEGF signaling pathway / 0.6 / Akt2