May 26, 2016
CURRICULUM VITAE
ANNIKA MAI OLSSON HOFSTETTER
Contact Information
Name Annika Mai Olsson Hofstetter
Office Address 1900 Ninth Avenue, M/S JMB-9
Seattle, WA 98101
Office Phone (206) 884-1699
Office Fax (206) 884-7175
Work Email
Personal Data
Place of Birth Pullman, Washington
Citizenship United States
Date of Birth September 24, 1976
Education
9/1994 –4/1999 Bachelor of Arts and Science in Biological Sciences and American Studies, Stanford University, Stanford, CA. Received departmental honors.
Honors thesis: Insuring America's uninsured children: the crafting and implementation of the 1997 State Children's Health Insurance Program.
3/2001 – 5/2004 Master’s Degree in Pediatric Science, Department of Woman and Child Health, Karolinska Institute, Stockholm, Sweden.
Thesis: Interleukin-1b and respiratory control during the neonatal period in rodents.
8/2001 – 6/2006 Doctor of Medicine, University of Washington School of Medicine, Seattle, WA. Graduated with high honors.
3/2001 – 12/2006 Ph.D. in Pediatric Science, Department of Woman and Child Health, Karolinska Institute, Stockholm, Sweden.
Thesis: Apnea and infection in neonates: mediatory role of interleukin-1β and prostaglandin E2.
9/2009 – 5/2011 Master of Public Health in Epidemiology, Mailman School of Public Health, Columbia University, New York, NY.
Thesis: Timeliness of pediatric influenza vaccination compared to seasonal influenza activity in an urban underserved community, 2004-2008.
Postgraduate Training
6/2006 – 6/2009 Pediatric Residency, Columbia University, Children’s Hospital of New York, New York, NY.
7/2009 – 6/2011 Primary Care Clinician Research Fellowship in Community Health, Columbia University, Children's Hospital of New York, New York, NY.
Faculty Positions Held
7/2009 – 6/2011 Assistant in Clinical Pediatrics, Division of Child and Adolescent Health, Columbia University, New York, NY.
7/2011 – 8/2012 Instructor in Clinical Pediatrics, Division of Child and Adolescent Health, Columbia University, New York, NY.
9/2012 – 8/2014 Assistant Professor of Pediatrics, Division of Child and Adolescent Health, Columbia University, New York, NY.
9/1/2014 – Present Assistant Professor of Pediatrics, Division of General Pediatrics, University of Washington, Seattle, WA.
Hospital Positions Held
7/2009 – 8/2014 Assistant Attending Pediatrician, NewYork-Presbyterian Hospital, New York, NY.
9/1/2014 – Present Attending Physician, Seattle Children’s Hospital, Seattle, WA.
Honors
1999 U.S. Fulbright Scholarship, Department of Woman and Child Health, Karolinska Institute, Stockholm, Sweden.
2002 Durward A. Huckabay Scholarship, University of Washington School of Medicine, Seattle, WA.
2004 Karolinska Institute Research Travel Award, Stockholm, Sweden.
2004 Best Presentation, Interleukin-1b depresses respiration and anoxic survival via a prostaglandin-dependent pathway, Swedish Society for Perinatal Medicine Annual Meeting, Stockholm, Sweden.
2004 – 2005 Odland Scholarship, University of Washington School of Medicine, Seattle, WA.
2005 Department of Pediatrics Visiting Student Scholarship, Mayo Clinic, Rochester, MN.
2005 Elected Alpha Omega Alpha, University of Washington School of Medicine, Seattle, WA.
2010 Eastern Society of Pediatric Research Travel Award.
2011 Best Trainee Award, Academic Pediatric Association Region II/III Meeting, New York, NY.
Board Certification
2010 American Board of Pediatrics Certification
Current Licenses to Practice
2008 – 2015 New York State Medical License (#247955)
2014 – Present Washington State Medical License (#60476433)
Professional Organizations
2001 – 2006 Member, American Medical Association
2011 – 2013 Member, New York City Coalition for Immunization Initiatives, New York City Department of Health and Mental Hygiene, New York, NY
2006 – Present Member, American Academy of Pediatrics
2009 – Present Member, Academic Pediatric Association
Teaching Responsibilities
Student Mentorship
2012 – 2013 Noor Al-Husanyi, medical student, SUNY Downstate College of Medicine, Brooklyn, NY
2012 – 2014 Lauren Lappetito, high school student, Ursuline School, New Rochelle, NY
2015 – Present Natalia Oster, doctoral student, University of Washington, Seattle, WA
Pediatric Resident Teaching
2010 – 2013 Clinical Preceptor for Pediatric Residents and Medical Students, Columbia University, New York, NY.
2015 – Present Clinical Preceptor for Pediatric Residents and Medical Students, University of Washington Medical Center, Newborn Nursery, Seattle, WA.
Pediatric Resident Mentorship
2016 – Present Erika Lund, MD
Editorial Responsibilities
None.
Special National Responsibilities
None.
Special Local Responsibilities
2014 – Present Co-Leader, Maintenance of Certification Project, Physician champions to increase influenza vaccination rates for chronically fragile patients in the ambulatory clinics at Seattle Children’s Hospital, Seattle, WA.
2014 – Present Member, Influenza Steering Committee, Seattle Children’s Hospital, Seattle, WA.
Research Funding
Active Research Support
# 8608423 (PIs: Hofstetter/Rosenthal) 7/1/2013-2/29/2016
Pfizer Medical Education Group
A multilevel approach to understanding and reducing missed opportunities for vaccination among adolescents with chronic medical conditions.
This study aims to examine missed opportunities for vaccination of adolescents with chronic medical conditions and assess the impact of a technology-based intervention to reduce such missed opportunities.
5U01IP000457 (PIs: Englund/Klein) 2/1/2015-7/31/2016
Role: Co-Investigator
Centers for Disease for Control and Prevention
New Vaccine Surveillance Network.
The major aim is to examine effectiveness of new vaccines in the community using prospective surveillance.
Faculty Research Support Fund (PI: Hofstetter) 3/1/2015-9/30/2016
Seattle Children’s Research Institute’s Center for Clinical and Translational Research
Influenza vaccine declination among parents of children with chronic disease.
This study aims to better understand missed opportunities for and parent declination of influenza vaccination among children hospitalized during the 2014-2015 influenza season.
1R01HS022582 (PI: Stockwell) 7/1/2015-6/30/2018
Role: Co-Investigator
Agency for Healthcare Research and Quality
SINC: Synchronized Immunization Notifications.
This study aims to assess the impact of electronic health record reminders integrated with immunization information and forecasting from an immunization information system on receipt of recommended vaccines.
Pediatric Pilot Fund (PI: Opel) 10/1/2015-9/30/2016
Role: Co-Investigator
Seattle Children’s Research Institute’s Center for Clinical and Translational Research
Provider-parent communication about influenza vaccine.
This study aims to examine the architecture of provider-parent discussions about influenza vaccine at health supervision visits.
Completed Research Support
Swedish Institute & Swedish Information Service Research Award (PI: Hofstetter) 2000
Swedish SIDS Foundation Research Grant (PI: Hofstetter) 2002
Samaritan Foundation Research Grant (PI: Hofstetter) 2003
Mayflower Foundation Research Grant (PI: Hofstetter) 2001 – 2004
Sven Jerrings Fund Research Grant (PI: Hofstetter) 2001 – 2006
Freemason Children’s Foundation Grant (PI: Hofstetter) 2000 – 2007
* Awarded in person by Queen of Sweden.
Health Disparities Loan Repayment Program (PI: Hofstetter) 7/1/2009-6/30/2011
National Institutes of Health
The research studies supported during this grant period have two primary aims: 1) to examine influenza vaccination coverage and timeliness of urban low-income minority children; 2) to identify parental, provider, and systems-based factors that influence influenza vaccination of this population.
U50 CU220700 (PI: LaRussa) 9/29/2001-9/30/2012
Role: Sub-Investigator
Centers for Disease for Control and Prevention
Clinical Immunization Safety Assessment Network (CISA)
The major goals of this project are to establish a center that serves as a resource to health care providers, a center for referring patients with immunization-related adverse events, and a hub for the implementation of studies addressing immunization safety issues.
U50 CU220700 (PI: LaRussa) 10/8/2008-9/30/2012
Role: Sub-Investigator
Centers for Disease for Control and Prevention
Retrospective review of post-vaccination adverse events in patients with mitochondrial disorders
The purpose of this study is to assess the role of extrinsic factors (infections and immunizations) in the metabolic and clinical progression of disease in children with primary mitochondrial disorders.
1U01IP000313 (PI: Stockwell) 9/1/2010-8/31/2013
Role: Co-Investigator
Centers for Disease for Control and Prevention
Text4Health-Kids: Text message reminder-recalls for early childhood vaccination
The study aims to determine the efficacy of text message vaccine reminder-recalls to increase coverage rates and timeliness of MMR (Dose 1) and Hepatitis A (Dose 2) vaccination.
R40MC17169 (PI: Stockwell) 2/1/2010-1/31/2014
Role: Co-Investigator
HRSA MCH Research Program
Textfluenza: Using technology to promote flu vaccination in underserved maternal and child populations
The goal of this project is to evaluate the efficacy, ease of implementation, and costs of targeted, tailored text message alerts for two populations at high risk for severe influenza, children and pregnant women.
Irving Institute/Clinical Trials Pilot Award (PI: Hofstetter) 7/1/2013-6/30/2014
Columbia University
A multilevel approach to understanding and optimizing influenza and pneumococcal vaccination of children with chronic medical conditions
This study aims to examine factors impacting influenza and pneumococcal vaccination of children with chronic medical conditions as well as acceptability and feasibility of using health technology to address barriers to vaccinating this high-risk population.
IISP # 39120 (PI: Soren) 5/22/2012-7/31/2015
Role: Co-PI
Merck Investigator Studies Program
Human papillomavirus vaccination and cervical cytology abnormalities among adolescent and young adult females from an urban underserved community: a retrospective cohort study
The purpose of this study is to examine HPV vaccination and Pap smear screening patterns among adolescent and young adult females from an urban underserved community.
Bibliography
a. Manuscripts in Refereed Journals
1. Olsson A, Kayhan G, Lagercrantz H, Herlenius E. Interleukin-1b depresses respiration and anoxic survival via a prostaglandin-dependent pathway in neonatal rats. Pediatric Research. 2003. 54(3):326-331.
2. Hofstetter AO, Herlenius E. Interleukin-1b depresses hypoxic gasping and autoresuscitation in neonatal DBA/1lacJ mice. Respiratory Physiology and Neurobiology. 2005. 146(2-3):135-146.
3. Hofstetter AO, Saha S, Siljehav V, Jakobsson PJ, Herlenius E. Prostaglandin E2 mediates respiratory depression induced by interleukin-1β in mice and human neonates. Proceedings of the National Academy of Sciences. 2007. 104(23):9894-9899.
* Featured in: “Baby’s Breath.” Research Highlights. Nature Medicine. 2007. 13(7):789.
4. Hofstetter AO, Legnevall L, Herlenius H, Katz-Salamon M. Cardiorespiratory development in extremely preterm infants: vulnerability to infection and persistence of events beyond term-equivalent age. Acta Paediatrica. 2008. 97(3):285-292.
5. Siljehav V, Hofstetter AO, Jakobsson PJ, Herlenius H. mPGES-1 and Prostaglandin E2 - vital role in inflammation, hypoxic response and survival. Pediatric Research. 2012. 72(5):460-467.
6. Hofstetter AM, Natarajan K, Andres Martinez R, Rabinowitz D, Vawdrey DK, Stockwell MS. Influenza vaccination coverage and timeliness among children requiring two doses, 2004-2009. Preventive Medicine. 2013. 56(3-4):165-170.
7. Stockwell MS, Martinez RA, Hofstetter A, Natarajan K, Vawdrey DK. Timeliness of 2009 H1N1 vaccine coverage in a low-income pediatric and adolescent population. Vaccine. 2013. 31(16):2103-2107.
8. Hofstetter AM, Natarajan K, Rabinowitz D, Andres Martinez R, Vawdrey DK, Arpadi S, Stockwell MS. Timeliness of pediatric influenza vaccination compared to seasonal influenza activity in an urban community, 2004-2008. American Journal of Public Health. 2013. 103(7):e50-58.
9. Hofstetter AM, Vargas C, Kennedy A, Kitayama K, Stockwell MS. Parental and provider preferences and concerns regarding text message reminder-recalls for early childhood vaccinations. Preventive Medicine. 2013. 57(2):75-80.
10. Hofstetter AM, Rosenthal SL. Health care professional communication about STI vaccines with adolescents and parents. Vaccine. 2014. 32(14):1616-1623.
11. Hofstetter AM, Rosenthal SL, Stanberry LR. Current thinking on genital herpes. Current Opinion in Infectious Diseases. 2014. 27(1):75-83.
12. Hofstetter AM, Stockwell MS, Al-Husayni N, Ompad D, Natarajan K, Rosenthal SL, Soren K. HPV vaccination: Are we initiating too late? Vaccine. 2014. 32(17):1939-1945.
13. Hofstetter AM, Jakob K, Klein NP, Dekker CL, Edwards KM, Halsey NA, Baxter R, Williams SE, Graham PL, LaRussa PS. Live vaccine use and safety in DiGeorge syndrome. Pediatrics. 2014. 133(4):e946-954.
14. Tsui J, Hofstetter AM, Soren K. Cervical cytology screening patterns among low-income, minority adolescents in New York City following the 2009 ACOG guidelines. Preventive Medicine. 2014. 63:81-86.
15. Hofstetter AM, Rosenthal SL. Factors impacting HPV vaccination: lessons for health care professionals. Expert Review of Vaccines. 2014. 13(8):1013-1026.
16. Broutet N, Fruth U, Deal C, Gottlieb SL, Rees H; participants of the 2013 STI Vaccine Technical Consultation. Vaccines against sexually transmitted infections: the way forward. Vaccine. 2014. 32(14):1630-1637.
17. Hofstetter AM, Barrett A, Stockwell MS. Factors impacting influenza vaccination of urban low-income Latino children under nine years requiring two doses in the 2010-2011 season. Journal of Community Health. 2015. 40(2):227-234.
18. Stockwell MS, Hofstetter AM, DuRivage N, Barrett A, Fernandez N, Vargas C, Camargo S. Text message reminders for second dose of influenza vaccine: a randomized controlled trial. Pediatrics. 2015. 135(1):e83-91.
19. Stockwell MS, Catallozzi M, Camargo S, Ramakrishnan R, Holleran S, Findley S, Kukafka R, Hofstetter AM, Fernandez N, Vawdrey D. Registry-linked electronic influenza vaccine provider reminders: a cluster-crossover trial. Pediatrics. 2015. 135(1):e75-82.
20. Hofstetter AM, Vargas CY, Camargo S, Vawdrey DK, Kharbanda EO, Stockwell MS. Impacting delayed pediatric influenza vaccination: a randomized controlled trial of text message reminders. American Journal of Preventive Medicine. 2015. 48(4):392-401.
21. Hofstetter AM, LaRussa P, Rosenthal SL. Vaccination of adolescents with chronic medical conditions: special considerations and strategies for enhancing uptake. Human Vaccines & Immunotherapeutics. 2015. 11(11):2571-2581.
22. Siljehav V, Hofstetter AM, Leifsdottir K, Herlenius E. Prostaglandin E2 mediates cardiorespiratory disturbances during infection in neonates. J. Pediatrics. 2015. 167(6):1207-1213.
23. Hofstetter AM, DuRivage N, Vargas CY, Camargo S, Vawdrey DK, Fisher A, Stockwell MS. Text message reminders for timely routine MMR vaccination: a randomized controlled trial. Vaccine. 2015. 33(43):5741-5746.
24. Hofstetter AM, Lacombe K, Klein EJ, Jones C, Strelitz B, Jacobson E, Ranade D, Ward ML, Mijatovic-Rustempasic S, Evans D, Wikswo M, Bowen MD, Parashar UD, Payne DC, Englund JA. Rotavirus vaccine uptake, shedding, and lack of nosocomial spread in infants hospitalized in the NICU. Open Forum Infectious Diseases. In Press. (Abstract #1920 from IDWeek, 2015, San Diego, CA).
25. Hofstetter AM, Ompad D, Stockwell MS, Rosenthal SL, Soren K. HPV vaccination and cervical cytology outcomes among urban low-income minority females. JAMA Pediatrics. 2016. 170(5):445-452.
b. Book chapters
None.
c. Published books, videos, software
None.
d. Other publications
None.
e. Abstracts
Hofstetter AM, Martinez RA, Natarajan K, Stockwell MS. Timeliness of pediatric influenza vaccination compared to seasonal influenza activity in an urban underserved community, 2004-2008. 45th National Immunization Conference, Washington, D.C., 2011. Poster Presentation, Presenter: Stockwell MS.
Hofstetter AM, Martinez RA, Natarajan K, Stockwell MS. Timeliness of pediatric influenza vaccination compared to seasonal influenza activity in an urban underserved community, 2004-2008. Academic Pediatric Association Region II/III Meeting, New York, NY, 2011. Platform Presentation, Presenter: Hofstetter AM.