Supplementary Table 2. Pathway assay of Genes up-regulated and down-regulated with BP8 treatment in B cells

Pathway / Fold change
Retinol metabolism - Mus musculus (mouse)
Adh7 / 14.9736
Cyp4a10 / 0.6241
Rdh10 / 1.5082
Chemokine signaling pathway - Mus musculus (mouse)
Ccr6 / 2.1500
Cxcl12 / 0.6651
Gnai1 / 5.0191
Gng3 / 0.0001
Gng7 / 1.7187
Gngt1 / 0.1464
Ikbkg / 2.5088
Plcb1 / 1.5055
Rasgrp2 / 0.1357
Jak–Stat pathway
Ctf1 / 1.5064
Ep300 / 0.3865
Il12rb2 / 0.6357
Il13 / 0.5810
Lifr / 5.0038
B cell receptor signaling pathway - Mus musculus (mouse)
Ikbkg / 2.5088
Nfat5 / 1.6333
Ppp3r2 / 0.6664
Notch signaling pathway - Mus musculus (mouse)
Cir1 / 0.6176
Ep300 / 0.3865
Rbpjl / 1.7493
Toll-like receptor signaling pathway - Mus musculus (mouse)
Ikbkg / 2.5088
Mapk10 / 0.1591
Tlr3 / 1.7233
Cytokine-cytokine receptor interaction - Mus musculus (mouse)
Amh / 3.3756
Ccr6 / 2.15
Ctf1 / 1.5064
Cxcl12 / 0.6651
Il12rb2 / 0.6357
Il13 / 0.581
Inhbc / 5.2098
Lifr / 5.0038
MAPK signaling pathway - Mus musculus (mouse)
Cacna1a / 0.2333
Cacna1s / 3.5027
Cacna2d1 / 0.134
Cacnb4 / 1.8173
Dusp16 / 2.7514
Fgf13 / 1.5174
Fgf14 / 1.8077
Fgfr3 / 0.4337
Fgfr4 / 3.0237
Flna / 12.3514
Flnc / 1.8448
Ikbkg / 2.5088
Mapk10 / 0.1591
Pak2 / 21.2174
Pla2g12b / 2.0145
Ppp3r2 / 0.6664
Rasgrp2 / 0.1357
Stk3 / 0.6429
Wnt signaling pathway - Mus musculus (mouse)
Ep300 / 0.3865
Fzd6 / 1.7023
Mapk10 / 0.1591
Nfat5 / 1.6333
Plcb1 / 1.5055
Ppp3r2 / 0.4802
Prickle1 / 0.6664
Sfrp5 / 1.5243
Siah1a / 2.184
Tcf7l1 / 0.6462
Wnt2 / 1.5147
Wnt5b / 0.2767
Calcium signaling pathway - Mus musculus (mouse)
Adra1a / 0.6058
Atp2b2 / 2.2503
Cacna1a / 0.2333
Cacna1s / 3.5027
Chrm5 / 1.5318
Grm1 / 3.6107
Grm5 / 2.3318
Mylk / 0.2952
Plcb1 / 1.5055
Plcd4 / 3.5944
Plcg1 / 0.6471
Ppp3r2 / 0.6664
Ptger3 / 9.093
Slc25a31 / 0.5687

Note: To identify the genes that are differentially expressed, we performed a Fold-change screening between the two groups obtained from the experiment. The threshold we used to screenregulated genes is Fold Change>=1.5.