Discipline Working Curriculum

Syllabus
042-18-25.1.125/01 – 2016 / Red. № 1 from 08.09.2016 / Page1from 12
MINISTRY OF EDUCATION AND SCIENCE OF THE REPUBLIC OF KAZAKHSTAN
SHAKARIMSTATEUNIVERSITY OF SEMEY
Document SMQ 3 level / Syllabus / Syllabus
042-18-25.1.125/01– 2016
Discipline working curriculum (syllabus)
"Basis of biochemistry " / Edition № 1from 8 September 2016

DISCIPLINE WORKING CURRICULUM

(SYLLABUS)

Name of the discipline: «Basis of biochemistry»

Amount of credits: 3

Code – specialty name:

5BB080100 – Agronomy

5B080700 – Forests and forestry

5B080300 – Hunting study and fur-farming

5B080200 – Technology of production animal products

5B060800 – Ecology

5B073100 – Health and safety and protection of environment

5B120100 – Veterinary medicine

5B120200 – Veterinary Sanitation

Faculty, Department:Agrarian Faculty, Department of Ecology and Environmental ProtectionDepartment,Agrotechnology and forest resources, Department of Animal husbandry and Hunting with basics on morphology, Department of Veterinary medicine, Department of Veterinary sanitation

Semey 2016

Foreword

1 ELABORATED

Author: Melnik M.S., Senior Lecturer______«31 august» 2016 y.

2 DISCUSSED

2.1 Chair meeting «Department of Ecology and Environmental Protection»

Record from «31» august 2016 y, № 1

Head of the chair ______Zh.K. Kabisheva

2.2 Faculty Educational and Methodological Board meeting
agrarian Faculty

Record from «1» september2016, №1.

Chair man ______A.V. Tleubaeva

3 APPROVED

Approved and recommended to publish at University Educational and Methodological Board’s meeting

Record from «8» September 2016, № 1.

Chairman, Vice-rector for Academic and Methodology Work ______G.K. Iskakova

IMPLEMENTED for the first time

CONTENT

1 GENERAL REGULATION

2 COURSE CONTENT AND HOURS DISTRIBUTION BY LESSON TYPES

3 COURSE POLICY

4 GRADING POLICY

5 LITERATURE AND INTERNET-RESOURSES

1 GENERAL REGULATIONS

1.1 General information about instructor and course

Instructor’s full name:Melnik Marina Sergeevna

Academic degree, title: Senior Lecturer of the Department of Ecology and Environmental Protection

Faculty, chair: Agrarian Faculty, Department of Ecology and Environmental Protection

Contact information tel.: 53-07-92, e-mail - , educational building number 8, office 128;

1.2 Course short description

Basic discipline, the component of choice.

Discipline “Biochemistry” is a component for selection of basic disciplines. This syllabus is developed based on the following regulating documents:

- Resolution of the Government dated August 23, 2012 № 1080 (in RK Government amended by the Resolution № 292 of 5/13/2016);

- Curriculum subjects "Environmental education and the outlook"

Biochemistry is the branch of science that explores the chemical processes within and related to living organisms. It is a laboratory based science that brings together biology and chemistry. By using chemical knowledge and techniques, biochemists can understand and solve biological problems.

1.3 Course study aims

The formation of systematic knowledge about the structure of the features and properties of chemical compounds that are part of the body; the acquisition of knowledge about the mechanisms of various biochemical reactions in the human body, form the basis of its physiological functions.

1.4 Course study objectives

To give students knowledge about the main sections of biochemistry, practical skills of research of structure, properties of biopolymers and their structural components

1.5 Competences (study results)

At the end of the study student has to:

Know:

-Mechanism flow of basic biochemical processes in the body;

-classification, structure, biological role and metabolic pathways of main biomolecules included in the animal and plant cells, methods for storing and transmitting genetic information, the principles of energy transformation in biological systems, the main methods for the synthesis of biologically active substances, obtained on the basis of secondary metabolites, their use in industry and medicine, environmental problems in the technology of synthesizing these compounds and recycling opportunities during their production;

-structure, properties and biological functions of proteins, lipids, enzymes, carbohydrates and their effect on the body;

To be able to:

- conduct an analysis of the scientific literature, demonstrate a basic understanding of biochemistry, cells, put them into practice, critically analyze the information and present the results of research

- to solve problems and issues associated with the establishment of the amino acid sequence of protein structures, the active site of enzymes, biological activity of co-enzymes and other biomolecules;

Have skills:

- synthesis, separation and identification of biologically active compounds

Вe competent:

-the processes occurring in the body

1.6 Pre –requisites

An oriented professional foreign language

Ecology and Sustainable Development

1.7 Post-requisites

Graduate work

1.8 Extract from academic curriculum

Extract from academic curriculum in Table 1

Table 1

Course / Term / Credits / Lecture
hours / Practice lessons
hours / Lab.
hours / IWS / Total / Form of control
3 / 6 / 3 / 30 / 15 / 90 / 135 / exam

2 COURSE CONTENT AND HOURS DISTRIBUTION BY LESSON TYPES

Course content and hours distribution by lesson types presented in Table 2

Table 2

№ / Module. Topic / Hours
Lecture / Lab. / Pract. / SIW / Literature
1 / 2 / 3 / 4 / 5 / 6 / 7
Module 1.Introduction.
Biochemistrysubject / 1 / 1 / 20 / 5.1.1
The main principles of chemical logic of a live condition. The concept about macro- and microelements. / 1 / 5.1.1-5.1.6
5.2.1-5.2.4
5.3.1-5.3.3
Module 2.Aminoacids.
Amino acids: classification, structure, stereochemistry, physical and chemical properties and classification amino acids forming proteins. / 2 / 2 / 5.1.1-5.1.6
5.2.1-5.2.4
5.3.1-5.3.3
Modul 3. Proteins.
Primary structure of proteins. Secondary, tertiary and quaternary structures. Chemical properties and methods of definition of primary structure of proteins. Classification of proteins. The role of proteins in a food. / 4 / 4 / 5.1.1-5.1.6
5.2.1-5.2.4
5.3.1-5.3.3
Modul 4. Enzymes.
The nomenclature and classification of ferments. Frame and catalytic properties of ferments. Temperature effect, рН, concentration of ferment and substrate for speed of enzymatic reactions. Regulation of activity of ferments / 2 / 2 / 20 / 5.1.1
5.1.2
5.1.3
5.1.5
5.1.6
Modul 5. Vitamins
The definition, constitution and classification of vitamins and their role in enzymatic reactions and in exchange processes. / 4 / 1 / 5.1.1-5.1.6
5.2.1-5.2.4
5.3.1-5.3.3
Modul6.Carbohydrates
Classification of carbohydrates and their most important reactions. Disaccharides and polysaccharides: lactose, maltose, sucrose, starch, glycogen, cellulose, quinine. The role of carbohydrates in a food. / 4 / 2 / 5.1.1-5.1.6
5.2.1-5.2.4
5.3.1-5.3.3
Modul7.Lipids
Biomedical value of lipids. Frame and classificationof lipids. The constitution and transport properties of cellular membranes. / 2 / 2 / 20 / 5.1.1-5.1.6
5.2.1-5.2.4
5.3.1-5.3.3
Modul8. Hormones
Classification of hormones and their most important functions / 2 / 1 / 5.1.1-5.1.6
5.2.1-5.2.4
5.3.1-5.3.3
Modul 9. Nucleicacids
Biological value of nucleic acids. Deoxyribonucleicand ribonucleic acids. Nucleotides. A constitution and functions in alive organisms. Transfer of ancestral features. Biosynthesis of protein. Processes of replication, a transcriptional and translation. A mutagenesis and hereditary diseases. Biotechnology and gene engineering. / 2 / 1 / 5.1.1-5.1.6
5.2.1-5.2.4
5.3.1-5.3.3
Modul10. Metabolism
Concept about a metabolism and metabolic paths: the katabolism and anabolism. A metabolism and reception of biochemical energy. Role of АТР in an energy exchange. / 2 / 1 / 5.1.1-5.1.6
5.2.1-5.2.4
5.3.1-5.3.3
Proteins metabolism. Carbohydrates metabolism. / 4 / 30 / 5.1.1-5.1.6
5.2.1-5.2.4
5.3.1-5.3.3
30 / 15 / 90

2.1 Tasks for 1st-2ndMidtermExam.

Tasks for 1stMidtermExam.

1. Introduction. Metabolic Regulation
2. Introduction to biochemistry. Vitamins. Enzymes. Hormones.
3. Energy metabolism
4. Carbohydratemetabolism
5. Lipid metabolism
6. Protein metabolism
7. Amino acidmetabolism. Nucleotide metabolism.
8. Protein biosynthesis
9. Unity and relationship of metabolisms

Tasks for 2ndMidtermExam.

1. Introduction. Metabolic Regulation
2. Introduction to biochemistry. Vitamins. Enzymes. Hormones.
3. Energy metabolism
4. Carbohydratemetabolism
5. Lipid metabolism
6. Protein metabolism
7. Amino acidmetabolism. Nucleotide metabolism.
8. Protein biosynthesis
9. Unity and relationship of metabolisms

3 COURSE POLICY

Attendance is strictly necessary. If for any reason a student cannot attend, then a student is responsible for all the material.

Control tasks are required to perform and should be given on time. The work carried out with a delay, will automatically be assessed below.

The results of the Midterm Examination are marked based on attendance, performance of students independent work in a timely manner, activity at lessons in oral or written form, the results of the Midterm Examination.

If a student missed a class and failed to pass the Midterm Exam in a timely manner due to illness or other valid reasons, documented by the organization, a student is entitled to an individual passing of Midterm Exam. In this case, specific date of Midterm Exam is set according to the provided documents.

Any cheating or plagiarism (use, copying works of the other students) is forbidden, and the student will not be allowed to present at the lesson and / or there will be penalty assessment "unsatisfactory".

Cell phones must to be turned off during lessons.

4 ACADEMIC GRADING POLICY

In each discipline, irrespective of the number of credits, 600 points are given for one academic term (1-7 week - 270 points and 30 points for attendance; 8-15 week - 270 points and 30 points for attendance).

The distribution of scores on the weeks and types of knowledge control is presented in Table 3.

Table 3

№ week / Theme of lab., practical lesson, seminar, SIW / Control type / Total scores
1 / 2 / 4 / 3
1-7 / Attendance of all classes
from 1st up to 7th week / Non - attendance is only noted / 30
Laboratory work, practical class, seminar, SIW
1 / Biochemistry subject / Combinedsurvey / 15
2 / Amino acids: classification, structure, stereochemistry, physical and chemical properties and classification amino acids forming proteins. / Combinedsurvey / 15
3 / Primary structure of proteins. Secondary, tertiary and quaternary structures.
IWS 1:Historyofbiochemistry. / Combinedsurvey
presentation / 15
55
4 / Classification of proteins. The role of proteins in a food. / combinedsurvey / 15
5 / The nomenclature and classification of ferments. Frame and catalytic properties of ferments. / combinedsurvey / 15
6 / Temperature effect, рН, concentration of ferment and substrate for speed of enzymatic reactions. Regulation of activity of ferments.
IWS 2:Cell is a basic structural element of a live matter. / combinedsurvey
presentation / 15
55
7 / 1 Midterm Exam / combinedsurvey / 70
Total scores by the academic results from 1st up to 7th week / 30+270=
300
8-15 / Attendance of all types classes from 8th up to 15th week / Non- attendance is only noted / 30
Practical class, seminar, SIW
8 / The definition, constitution and classification of vitamins and their role in enzymatic reactions and in exchange processes. / Combinedsurvey / 15
9 / Classification of carbohydrates and their most important reactions. Disaccharides and polysaccharides: lactose, maltose, sucrose, starch, glycogen, cellulose, quinine. The role of carbohydrates in a food. / Combinedsurvey / 15
10 / Biomedical value of lipids. Frame and classificationof lipids. The constitution and transport properties of cellular membranes.
IWS 3:General characteristics of the vitamins. / Combinedsurvey
report / 15
55
11 / Classification of hormones / Combinedsurvey / 15
12 / Nucleicacids / Combinedsurvey / 15
13 / Concept about a metabolism and metabolic paths / Combinedsurvey / 15
14 / Preparation of stand, posters about healthy lifestyles.
IWS 4: Biotechnology and gene engineering. / Сombinedsurvey
report / 15
55
15 / 2 Midterm Exam / Combinedsurvey / 70
Total scores by the academic results from 8th up to 15th week / 30+270=
300
Examination total score / 400
Academic period score / 1000

The student is allowed for the exam on the subject, if student total rating ranges from 300 to 600 points per semester, and if the student has no missed assignment on disciplines that are prerequisites of the discipline.

The examination of the discipline is defined as the sum of the maximum performance indicators: total certification (60%), exam (40%), which is 100%.

Final evaluation of students' knowledge on the subject is determined by the scale (Table 4).

Table 4

Score grading alphabetic scale of knowledge assessment

Letter grade / Grade point value / Percentage / Traditional grading scale
А / 4,0 / 95-100 / Excellent
А- / 3,67 / 90-94
В+ / 3,33 / 85-89 / Good
В / 3.00 / 80-84
В- / 2,67 / 75-79
С+ / 2,33 / 70-74 / Satisfactory
С / 2,00 / 65-69
С- / 1,67 / 60-64
Д+ / 1,33 / 55-59
Д / 1,00 / 50-54
F / 0,00 / 0-49 / Unsatisfactory

5 LITERATURE AND INTERNET-RESOURSES

5.1 Basic literature

5.1.1 D. Hames, N. Hooper Biochemistry - Taylor & Francis e-Library, 2006

5.1.2. Graff,S. Essays in Biochemistry/ S. Graff.- [репринтноеизд-е].- New York: Book Renaissance, 2014 [1956].- 345 p.

5.1.3 Сеитов З.С. Биохимия. –Алматы: Агроуниверситет, 2000.-897 с.

5.1.4. Биологическая химия/под ред. Н.И. Ковалевской.-М.: Академия, 2009.-255 с.

5.1.5 Berg,J.M. Biochemistry /Jeremy M. Berg, John L. Tymoczko, LubertStryer; with Gregory J. Gatto, Jr.-International seventh edition/ J.M. Berg.- New York: W.H. Freeman and Company, 2012.- 1098 с.

5.1.6 Voet,D. Biochemistry /Donald Voet, Judith G. Voet.-4-th edition/ D. Voet.- UnitedStatesofAmerica: JohnWileySons, Inc, 2011.- 1428 с.

5.1.7 Кайрханов К.К. Методические указания к лабораторным занятиям по биохимии /издание третье, переработанное и дополненное/ Семипалатинск, ЦНТИ, 2003.

5.2 Additionalliterature

5.2.1 Березов Т.Т., Коровкин Б.Ф., Биохимия. -Москва: 2000.-520 с.

5.2.2 Строев Е.А. Биологическая химия. -М.: 1986.-480 с.

5.2.3 Николаев А.Я. Биохимия. -Москва: 1989.-495 с.

5.2.4 Строев Е. А., Макарова А. А., Практикум по биологической химии. -М.: «Высшая школа», 1986. -231с.

5.3 Internet-resources

5.3.1 Подред. Е.С. Северина. Биохимия: Учеб. для вузов, 2003. 779 с.

5.3.2 Ridgway N., McLeod R., Vance J.E., Vance D. Biochemistry of Lipids, Lipoproteins and Membranes, 624 pages. Elsevier, 2012.

5.3.3 John W. Pelley, Edward F. Goljan Rapid Review Biochemistry//Chapter 3 – Membrane biochemistry and Signal Transduction, 208 pages. Elsevier, 2011.

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