Content Editor & Webmaster:
Please read the Disclaimer
Antiinfectives
General Rx
Renal Rx
Transplant Rx
Pkinetics
Educational
KidneyWorks
Clinical Tools / Is This Drug Dialyzed?
In the following table indicates whether a given drug is removed by conventional hemodialysis or not and the approximate extent of removal (a rounded, mid-range figure). Removal by cotinuous renal replacement therapy methods may be added in the future. / The information in the table below was derived from the following sources:
- Choi, L., and C.A. Johnson. 1987. Removal of drugs by hemodialysis (HD) and peritoneal dialysis (PD). Dialysis & Transplantation 16(10):538.
- Knoben, J.E. and P.O. Anderson - Eds. Handbook of Clinical Drug Data. 1993. pp171-194.Drug Intelligence Publications, Inc.
- Schrier, R.W. and J.G. Gambertoglio - Eds. Handbook of Drug Therapy in Liver and Kidney Diseases.
acetaminophen / Yes 30 / chlorpromazine / No / epinephrine / ?
acetazolamide / Yes 35 / chlorpropamide / ? / erythromycin / No
acyclovir / Yes 75 / chlorthalidone / No / ethacrynic acid / No
albuterol / ? / cimetidine / No / ethambutol / No
allopurinol / Yes 35 / ciprofloxacin / No / ethosuximide / Yes 60
alprazolam / No / cisapride / ?? / famotidine / No
amantadine / No / clarithromycin / ? / fentanyl / ?
amikacin / Yes 75% / clavulanic acid / Yes / flecainide / No
amiloride / ? / clindamycin / No / fluconazole / Yes 35
amiodarone / No / clonazepam / No / flucytosine / Yes 75
amitriptyline No / clonidine / No / fluoxetine / ?
amoxicillin / Yes 35 / clorazepate / No / fluphenazine / No
amphotericin B / No / clozapine / ? / flurazepam / No
ampicillin / Yes 35 / codeine / ? / foscarnet / Yes 75
amrinone / ? / colchicine / No / furosemide / No
aspirin / Yes 75 / cortisone / No / ganciclovir / Yes 75
astemezole / ? / cyclophosphamide / Yes 35 / gemfibrozil / ?
atenolol / Yes 35 / cyclosporine / No / gentamicin / Yes 75
azathioprine / Yes 5 - 50 / desipramine / ? / glipizide / ?
aztreonam / Yes 35 / dexamethasone / ? / glyburide / No
betamethasone / ? / diazepam / No / granisetron / ?
bretylium / Yes 35 / diazoxide / No / haloperidol / No
bumetanide / ? / dicloxicillin / No / heparin / No
captopril / Yes 35 / digoxin / No / hydralazine / ?
carbamazepine / No / diltiazem / No / hydrochlorothiazide / ?
carbidopa/levodopa / ? / diphenhydramine / ? / hydrocodone / ?
cefazolin / Yes 35 / dipyridamole / Yes / hydrocortisone / ?
cefotaxime / Yes 35 / disopyramide / No / hydromorphone / ?
cefotetan / Yes 35 / doxepin / No / hydroxyzine / ?
ceftazidime / Yes 35 / doxycycline / No / ibuprofen / No
ceftriaxone / No / enalapril / Yes 25 / imipenem / cilastatin / Yes 60 / 35
cephalexin / Yes 35 / encainide / ? / imipramine / No
chloral hydrate / Yes 60 / ephedrine / ? / indomethacin / ?
chloramphenicol / Yes 35 / epinephrine / ? / insulin / No
chlorpheniramine / No / erythromycin / No / isoniazid / Yes 75
isoproterenol / ? / nitroglycerin / No / sulbactam / Yes
isosorbide / No / nitroprusside / ? / sulfamethoxazole / Yes 25
itraconazole / No / nizatidine / ? / sulindac / ?
ketoconazole / No / nortriptyline / No / tacrolimus / No
ketorolac / ? / omeprazole / ? / tamoxifen / ?
labetalol / No / ondansetron / ? / temazepam / No
levothyroxine / ? / oxacillin / No / terbutaline / ?
lidocaine / No / oxazepam / No / terfenadine / ?
lithium / Yes 60 / oxycodone / ? / tetracycline / No
loperamide / ? / paroxetine / ? / theophylline / Yes 75
lorazepam / No / penicillin G / Yes 35 / thioridazine / No
mannitol / ? / pentamidine / ? / thiothixene / ?
meperidine / ? / pentazocine / ? / ticarcillin / Yes 35
metaproterenol / ? / pentobarbital / No / timolol / No
methadone / No / perphenazine / No / tobramycin / Yes 75
methotrexate / No / phenobarbital / Yes 60 / tocainide / Yes 25
methyldopa / Yes 25 / phenytoin / No / tolazamide / No
methylprednisolone / No / piperacillin / Yes 35 / tolbutamide / No
metoclopamide / No / piroxicam / ? / tolmetin / ?
metolazone / ? / prazosin / No / trazodone / ?
metoprolol / No / prednisolone / No / triamterene / ?
metronidazole / Yes 75 / prednisone / No / triazolam / No
mexiletine / No / primidone / Yes 35 / trifluoperazine / No
midazolam / ? / procainamide // NAPA / Yes 35 / trimethoprim / Yes 25
minocycline / No / prochlorperazine / ? / valproic acid / No
minoxidil / Yes / propoxyphene / No / vancomycin / removed by high-flux HD (35%)
morphine / ? / propranolol / No / valganciclovir / Yes, 50-75%
nadolol / Yes 35 / quinidine / No / venlafaxine / ?
nafcillin / No / ranitidine / No / verapamil / No
naproxen / No / reserpine / No / warfarin / No
neomycin / Yes 75 / rifampin / No / zidovudine / No
nicardipine / No / sertraline / ? / /
nifedipine / No / spironolactone / ? / /
nitrofurantoin / ? / sufentanil / ? / /
nimodipine / No / / /
/ / / /
theDrugMonitor / | / Nephrosite / | / Feedback
Copyrights ® 1997-2002 the Drug Monitor