Table S2 - Effects of VEGFA genotypes on changes in blood pressure of hypertensive patients in response toenalapril 10 mg/day after adjusting for selected variables.

Change in SBP (mmHg) / Change in MBP (mmHg) / Change in DBP (mmHg)
R²=0.17 / RMSE=11.82 / R²=0.20 / RMSE=8.13 / R²=0.21 / RMSE=8.19
Source / B / P / B / P / B / P
Age (years) / -0.22 / 0.147 / -0.08 / 0.470 / -0.14 / 0.184
Gender (male) / +1.78 / 0.371 / +2.51 / 0.072 / +2.19 / 0.117
Ethnicity (non-Whites) / -0.02 / 0.991 / +1.11 / 0.394 / +1.03 / 0.430
Smoking Status (current smoker) / +1.83 / 0.632 / +3.18 / 0.230 / +4.10 / 0.127
g.-2578C>A / P=0.526 / P=0.431 / P=0.671
B / P / B / P / B / P
CC / -2.21 / 0.601 / -2.98 / 0.318 / -1.05 / 0.724
CA / -2.86 / 0.330 / -1.54 / 0.445 / -1.61 / 0.427
AA / +5.06 / 0.319 / +4.52 / 0.199 / +2.66 / 0.449
g.-1154G>A / P=0.394 / P=0.227 / P=0.750
B / P / B / P / B / P
GG / +2.90 / 0.577 / +3.54 / 0.326 / +2.15 / 0.550
GA / -3.20 / 0.512 / -1.81 / 0.588 / -0.02 / 0.996
AA / +0.30 / 0.974 / -1.72 / 0.781 / -2.14 / 0.732
g.-634G>C / P=0.744 / P=0.703 / P=0.218
B / P / B / P / B / P
GG / +2.55 / 0.465 / +0.624 / 0.794 / +1.77 / 0.464
GC / -0.64 / 0.820 / -1.548 / 0.426 / -3.15 / 0.112
CC / -1.91 / 0.669 / +0.924 / 0.763 / +1.39 / 0.654

SBP:systolic blood pressure. MBP: mean blood pressure. DBP: diastolic blood pressure. R2: portion of variability explained by the model. RMSE: root mean square error. B: Parameter estimate.