Estimation parameters for Figure 1 and Table 3:

Height threshold: T = 3.16, p = 0.001 (0.993 corrected) Degrees of freedom = [1.0, 116.0]

Extent threshold: 100 voxels, p = 0.158 (0.547 corrected)Smoothness FWHM = 13.5 15.4 14.1 {mm} = 9.0 10.3 9.4 {voxels}

Expected voxels per cluster, <k> = 52.975 Search volume: S = 1040806 mm3 = 308387 voxels = 305.3 resels

Expected number of cluster, <c> = 0.79 Voxel size: [1.5, 1.5, 1.5] mm [1 resel = 870.68 voxels]

L = left, R = right

Estimation parameters for Figure 2 and Table 4:

Height threshold: T = 3.20, p = 0.001 (0.994 corrected)Degrees of freedom = [1.0, 78.0]

Extent threshold: 100 voxels, p = 0.16 (0.559 corrected)

Smoothness FWHM = 13.7 15.6 14.2 {mm} = 9.1 10.4 9.5 {voxels}

Expected voxels per cluster, <k> = 53.828Search volume: S = 1068728 mm3 = 316660 voxels = 303.9 resels

Expected number of clusters, <c> = 0.82Voxel size: [1.5, 1.5, 1.5] mm [1 resel = 901.66 voxels]

Estimation parameters for Figure 3 and Table 5

Height threshold: T = 3.20, p = 0.001 (0.995 corrected)Degrees of freedom = [1.0, 80.0]

Extent threshold: 100 voxels, p = 0.152 (0.555 corrected)

Smoothness FWHM = 13.5 15.4 13.9 {mm} = 9.2 10.2 9.3 {voxels}

Expected voxels per cluster, <k> = 51.475Search volume: S = 1067833 mm3 = 316395 voxels = 320.3 resels

Expected number of clusters, <c> = 0.81Voxel size: [1.5, 1.5, 1.5] mm [1 resel = 854.52 voxels]

Factor / Beta / SE / Za / p / 95% Confidence Interval
Type 1 Diabetes / -.0246 / .0054 / -4.56 / <0.001 / -.0352 / -.0138
Age / -.0013 / .0005 / -2.60 / 0.019 / -.0024 / -.0002
Handedness / -.0083 / .0132 / -0.62 / 0.53 / -.0345 / .0179
Gender / .0235 / .0051 / 4.61 / <0.001 / .0135 / .0336
Education (yrs) / .0010 / .0011 / 0.91 / 0.35 / -.0011 / .0032
Drug use / .0119 / .0074 / 1.61 / 0.112 / -.0028 / .0266
Depression / .0048 / .0053 / 0.91 / 0.37 / -.0057 / .0154
Alcohol abuse / -.0028 / .0092 / -0.30 / 0.76 / -.0211 / .0154
Constant / .5371 / .0314 / 17.1 / <0.001 / .4749 / .5994

Multiple regression model, type 1 diabetes (n=82) vs. healthy controls (n=36), for the left Superior Temporal Gyrus. Dependent variable is percentage gray matter