Publications
Trautmann, S., Richter, J., Muehlhan,M.,Hoefler, M., Wittchen, H-U., Domschke, K. Deckert, J., Stroehle, A., Hamm, A.O., Weber, H., Kircher, T., Aroltf, V., Gerlach, A. L., Alpers, G.W., Fydrich, T., Reif, A. (in revision). Does prior traumatization affect the treatment outcome of CBT for panic disorder? The roleofthe MAOA geneanddepressionsymptoms.
Schäfer, I., Pawils, S., Driessen, M., Härter, M., Hillemacher, T., Klein, M.,Muehlhan, M.,Ravens-Sieberer, U., Schäfer, M., Scherbaum, N., Schneider, B., Thomasius, R., Wiedemann, K., Wegscheider, K., Barnow, S. (accepted).Understanding the role of Childhood Abuse and Neglect as a cause and consequence of Substance Abuse: The German CANSAS-Network.European Journal of Psychotraumatology (EJPT)
Muehlhan, M.,Höcker, A., Höfler, A., Wiedemann, K., Barnow, S., Schäfer, I., & the CANSAS study group (accepted). Stress-related salivary alpha-amylase (sAA) activity in alcohol dependent patients with and without a history of childhood maltreatment.Psychopharmacology
Hilbert, K., Lueken, U.,Muehlhan, M.,Beesdo-Baum, K. (2017). Separating Generalized Anxiety Disorder from Major Depression using clinical, hormonal and structural MRI data: a multimodal machine learning study. Brain andBehavior
Trautmann, S., Muehlhan, M.,Kirschbaum, C., Wittchen, H-U.,Höfler, M., Stalder, T., PhDb, Steudte-Schmiedgen, S. (2017). Biological stress indicators as risk markers for increased alcohol use following traumatic experiences. AddictionBiology
Steudte-Schmiedgen, S., Wichmann, S., Stalder, T., Hilbert, K., Muehlhan, M.,Lueken, U., Beesdo-Baum, K., (2017). Hair cortisol concentrations and cortisol stress reactivity in generalized anxiety disorder, major depression and their comorbidity. Journal of Psychiatric Research 84:184-190
Hilbert, K., Pine, D.S., Muehlhan, M., Lueken, U., Steudte-Schmiedgen, S., Beesdo-Baum, K. (2015). Gray and white matter volume abnormalities in generalized anxiety disorder by categorical and dimensional characterization. Psychiatry Research Neuroimaging 3:314-320
Muehlhan, M., Kirschbaum, C., Wittchen, H-U., Alexander, N. (2015) Epigenetic variation in the serotonin transporter gene predicts resting state functionalconnectivity strength within the salience-network. Human Brain Mapping36:4361–4371
Weckesser LJ, Plessow F, Pilhatsch M, Muehlhan M, Kirschbaum C, Miller R. (2014).Do venepuncture procedures induce cortisol responses? A review, study, and synthesis for stress research. Psychoneuroendocrinology; 46: 88-99.
Muehlhan, M.,Marxen, M., Landsiedel, J., Malberg, H., Zaunseder, S. (2014). The effect of body posture on cognitive performance: a question of sleep quality. Frontiers in Human Neuroscience.8:171. doi: 10.3389/fnhum.2014.00171
Muehlhan, M., Lueken, U., Siegert, J., Wittchen, H-U., Smolka, M.N., & Kirschbaum, C. (2013). Enhanced sympathetic arousal in response to fMRI scanning correlates with task induced activations and deactivations. PLOS ONE8 (8), e72576
Mühlhan, M. (2012). Anxiety and Distress during Functional Magnetic Resonance Imaging (fMRI) Examinations: A Neglected Problem in Scientific Research. Faculty of Science, TechnischeUniversität Dresden
Lueken, U*., Muehlhan, M*., Evens, R., Wittchen, H.-U., & Kirschbaum, C. (2012). Within and between session changes in subjective and neuroendocrine stress parameters during magnetic resonance imaging: a controlled scanner training study.Psychoneuroendocrinology. doi:10.1016/ j.psyneuen.2012.01.003
(* both authors contribute equally to this manuscript)
Lueken, U., Kruschwitz, J. D., Muehlhan, M., Siegert, J., Hoyer, J., & Wittchen, H.-U (2011). How specific is specific phobia? Different neural response patterns in two subtypes of specific phobia. Neuroimage, 56, 363-372. doi:10.1016/j.neuroimage.2011.02.015.
Lueken, U., Muehlhan, M., Wittchen, H.-U., Kellermann, T., Reinhardt, I., Konrad, C., Lang, T., Wittmann, A., Ströhle, A., Gerlach, A. L., Ewert, A., & Kircher, T. (2011). (Don’t) panic in the scanner! How panic patients with agoraphobia experience a functional magnetic resonance imaging session. European Neuropsychopharmacology. doi:10.1016/j.euroneuro.2010.12.002.
Muehlhan, M., Lueken, U., Wittchen, H.-U. & Kirschbaum, C. (2011). The scanner as a stressor: Evidence from subjective and neuroendocrine stress parameters in the time course of a functional magnetic resonance imaging session. International Journal of Psychophysiology, 79, 118-126.
Weerda, R., Muehlhan, M., Wolf, O.T., Thiel, C.M. (2010). Effects of Acute Psychosocial Stress on Working Memory Related Brain Activity in Men. Human Brain Mapping 31:1418–1429
M Meis, C Hilge, C Nocke, T Bräcker, V Lammers, M Lützen, R Machner, M Mühlhan, A Müller, B Silge, W Wempe, S Wolter, A Schick. (2005) Subjektive Einschätzung der Sprechstimme und der Hörumgebung in universitären Seminarräumen. Fortschritte der Akustik, DAGA '05, 441-442
Conference Abstracts, talksandposters
Alexander, N., Mühlhan, M.,Wankerl, M., Miller, R., Kirschbaum, C. (2016). Neural and endocrine correlates of SLC6A4 methylation profiles. 46. Annual Meeting of the International Society of Psychoneuroendocrinology, Miami, September 8.-11. September (Talk)
Muehlhan, M., & Alexander, N., (2016). Amygdaloid functional network architecture varies with epigenetic changes in the FKBP5 gene. 22nd Annual Meeting of the Organization for Human Brain Mapping (OHBM), Geneva June 26.-30. (Poster)
Muehlhan, M. & Alexander, N. (2016). DNA Methylierungsmuster innerhalb des FKBP5-Gens und funktionell-amygdaloidale Netzwerkarchitektur. 42. Tagung „Psychologie und Gehirn“. Berlin 26-28 Mai 2016 (Talk)
Mühlhan, M. (2015). Angst und Sucht aus neurobiologischer Perspektive. 3. Aktionstage zur seelischen Gesundheit. 9. Oktober 2015 Diakonisches Werk Dresden (Talk)
Alexander, N., Kirschbaum, C., Wittchen, H-U., Muehlhan, M. (2015). Die Bedeutung epigenetischer Variation im Serotonin-Transporter Gen für die funktionelle Ruhekonnektivität innerhalb des Salienznetzwerks13. Arbeitstagung der Fachgruppe Differentielle Psychologie (Talk)
Höcker, A., Mühlhan, M., Mollen, F., Holl, J., Wolff, S., Barnow, S., Schäfer, I. (2015). The impact of childhood abuse and neglect on acute stress reactivity in individuals with alcohol dependence. 4th German Health Research Meeting on Behavioural Disorders related to Violence, Neglect, Maltreatment and Abuse in Childhood and Adolescence(Poster)
Schäfer, J. & Mühlhan, M.(2015). Von der Vulnerabilität bis zur Störung: Biologische und kognitive Determinanten von Traumafolgen. 9. Workshopkongress fürKlinischePsychologie und Psychotherapie & 33. Symposium der Fachgruppe KlinischePsychologie und Psychotherapie der DGPs, (Symposium)
Mühlhan, M., Kirschbaum, C., Wittchen, H-U., Alexander, N.(2015). Auswirkungen der Serotonintransporter Methylierung auf die funktionelle Kopplung großer Hirnnetzwerke (large-scalebrainnetworks) (Talk). 9. Workshopkongress fürKlinischePsychologie und Psychotherapie & 33. Symposium der Fachgruppe KlinischePsychologie und Psychotherapie der DGPs, (Symposium)
Höcker, A., Mühlhan, M., Schäfer, I. (2015) Zusammenhänge zwischen frühen Traumata und der neuroendokrinen Stressantwort bei Patienten mit Alkoholabhängigkeit. 9. Workshopkongress fürKlinischePsychologie und Psychotherapie & 33. Symposium der Fachgruppe KlinischePsychologie und Psychotherapie der DGPs, (Symposium)
Höcker A, Mühlhan M, Mollen F, Holl J, Wolff S, Barnow S, Schäfer I (September, 2014). The impact of childhood abuse and neglect on cortisol awakening response in individuals with alcohol dependence. 3rd German health research meeting on behavioral disorders related to violence, neglect, maltreatment, and abuse in childhood and adolescence, Eichstätt.(Poster)
Höcker A, Mühlhan M, Schäfer I (September 2014). Zusammenhänge zwischen frühen Belastungen und der neuroendokrinen Stressantwort bei Patienten mit Alkoholabhängigkeit. Vortrag auf demDeutschen Suchtkongress, Berlin. (Talk)
Muehlhan, M., Wittchen, H.-U., Alexander, N. (2014). Effects of trait anxiety on neuralresponse to the Attentional Network Test. Annual Meetingof the Organization for Human BrainMapping Annual Meeting June 8.-12.2014 Hamburg Germany (Poster)
Markus Muehlhan, Hans-Ulrich-Wittchen, Nina Alexander (2013). Modulation von Aufmerksamkeitsnetzwerken durch verschiedene Ausprägungen dispositioneller Ängstlichkeit. Kongress der Deutschen Gesellschaft für Psychiatrie und Psychotherapie, Psychosomatik und Nervenheilkunde. 27.-30.11.2013, Berlin (Poster)
Markus Mühlhan (2013). Psychopathologie und Stress: Dysfunktionen neuroendokriner Regulationsprozesse. Kolloquium der Klinik für Psychiatrie und Psychotherapie, Universitätsklinikum Hamburg Eppendorf (UKE). Hamburg 26.09.2013 (invitedtalk)
Anja Höcker*, Markus Mühlhan*, Pia Bandurski, Philipp Hiller, Klaus Wiedemann, Ingo Schäfer (2013). Die Cortisol-Aufwachreaktion als Marker früher Traumatisierungen: Besonderheiten und methodische Herausforderungen bei Patienten mit Alkoholabhängigkeit. 2nd German health research meeting on behavioural disorders related to VIOLENCE, NEGLECT, MALTREATMENT and ABUSE in childhood and adolescence. Hamburg 23-24 September 2013 (*shared talk)
Schäfer I, Barnow S, Klein M, Mühlhan M, Scherbaum N, Driessen M, Thomasius R, Ravens-Sieberer U, Haerter M, Pawils S (2013) Childhood abuse and neglect as a cause and consequence of substance abuse - understanding risks and improving services (CANSAS). European Journal of Psychotraumatology 4 (Suppl 1): 40(talk)
Ingo Schäfer, Sven Barnow, Michael Klein, Markus Mühlhan, Martin Driessen, Norbert Scherbaum, Rainer Thomasius, Peter-Michael Sack, Ulrike Ravens-Sieberer, SilkePawils,Martin Härter (2012). Suchterkrankungen als Ursache und Folge früher Gewalt – der BMBF-Verbund „CANSAS“. DGPPN-Kongress, 21-24 November 2012, Berlin (talk)
Markus Muehlhan,Ulrike Lueken,Ricarda Evens, Clemens Kirschbaum (2012).MRT als Stressor: Erfassung, Auswirkungen und Reduktion von Stressreaktionen während funktioneller Magnetresonanztomographie (fMRT). 48. Kongress der Deutschen Gesellschaft für Psychologie (DGPs), 23-27 September 2012, Bielefeld (talk)
Ingo Schäfer, Sven Barnow, Michael Klein, Markus Mühlhan, Norbert Scherbaum, Martin Driessen, Rainer Thomasius, Peter-Michael Sack, Ulrike Ravens-Sieberer, Martin Härter, Silke Pawils (2012). Childhood Abuse and Neglect as a cause and consequence of Substance Abuse – understanding risks and improving Services (CANSAS). 1st German health research meeting on behavioural disorders related to violence, neglect, maltreatment, and abuse in childhood and adolescence, September 24-25, 2012, SchlossReisensburg (beiGünzburg) (talk)
Anja Höcker, Markus Mühlhan, Sven Barnow, Malte Stopsack, Ingo Schäfer (2012). Relationships between childhood abuse and the neuroendocrine response to stress in individuals with substance abuse.1st German health research meeting on behavioural disorders related to violence, neglect, maltreatment, and abuse in childhood and adolescence, September 24-25, 2012, SchlossReisensburg (beiGünzburg) (talk)
Markus Muehlhan, Ulrike Lueken, Hans-Ulrich Wittchen, Michael N. Smolkaand Clemens Kirschbaum (2012). Sympathetic stress reactions in response to fMRI scanning altered performance and neural activation pattern of interest. Annual Meeting of the Organization for Human Brain Mapping, June 10-14 2012, Beijing (poster)
Schäfer, I., Mühlhan, M., Menger, M., Lüdecke, D., Bong, S., Haupt, L., Marzok, M., Sehner, S., Wiedemann, K. (2012). Auswirkung früher Traumatisierung auf die Cortisolsekretion alkoholabhängiger Patienten unter psychosozialem Stress. 14. Jahrestagung der Deutschsprachige Gesellschaft für Psychotraumatologie DeGPT 08-11.03.2012 (talk)
Lueken, U., Kruschwitz, J.D., Hilbert, K., Muehlhan, M., Hoyer, J. & Wittchen, H.-U. (2010).Betterlooktwice: Stimulus processing in dental phobiausing a video-basedfMRIparadigm. Poster, 16th meetin of the Organization for Human brain mapping, Juni. 05-10, 2010, Barcelona (Spain) (poster)
Beesdo, K., Mühlhan, M., Lüken, U., Wittchen, H.-U., & Pine, D. S. (2009). Altered fear-circuitry in Generalized Anxiety Disorder: Preliminary data from an fMRI study. Poster. American College of Neuropsychopharmacology (ACNP) 48th Annual Meeting, 2009, 06.-10.12., Hollywood, Florida, USA. (poster)
Lueken, U., Muehlhan, M., Wittchen, H.-U. & Kirschbaum, C. (2009). How do subjects experience an fMRI session? Concordance between subjective and neuroendocrine stress indicators. Poster, 49th Annual Meeting of the Society for Psychophysiological Research (SPR), Berlin (Germany), Oct. 21 - 24, 2009. Psychophysiology, 46 (Suppl. 1), S37. (poster)
Lueken, U., Muehlhan, M., Wittchen, H.-U., Pfleiderer, B., Konrad, C., Ströhle, A., Wittmann, A., Reinhardt, I., Jansen, A. & Kircher, T. (2009). Angst vor dem Scanner? Befindlichkeit von Patienten mit Panikstörung & Agoraphobie im Verlauf einer fMRT-Untersuchung. Poster, Jahrestagung der Deutschen Gesellschaft für Psychiatrie, Psychotherapie und Nervenheilkunde (DGPPN), Berlin (Germany), Nov. 25-29, 2009. In F. Schneider & M. Grözinger (Hrsg.), Abstractbuch zum DGPPN Kongress 2009 (S.306). Deutsche Gesellschaft für Psychiatrie, Psychotherapie und Nervenheilkunde e.V. (poster)
Muehlhan, M., Lueken, U., Smolka, M. N. & Kirschbaum, C.(2009). Are your runs comparable? Differences in subjective and neuroendocrine stress indicators in the course of an fMRI session. Poster, 49th Annual Meeting of the Society for Psychophysiological Research (SPR), Berlin (Germany), Oct. 21 - 24, 2009. Psychophysiology, 46 (Suppl. 1), S37. (poster)
Muehlhan, M., Lueken, U., Wittchen, H.-U-, Kirschbaum, C. (2009). MRT als Stressor: Subjektive und neuroendokrine Veränderungen im Verlauf einer fMRT-Untersuchung.. Poster, Jahrestagung der Deutschen Gesellschaft für Psychiatrie, Psychotherapie und Nervenheilkunde (DGPPN), Berlin (Germany), Nov. 25-29, 2009. In F. Schneider & M. Grözinger (Hrsg.), Abstractbuch zum DGPPN Kongress 2009 (S.283). Deutsche Gesellschaft für Psychiatrie, Psychotherapie und Nervenheilkunde e.V. (poster)
Mühlhan, M., Weerda,. Wolf, O.T., Thiel, C.M. (2008) Effects of psychosocial stress on neural correlates of selective attention and working memory processes. 39th conference of International Society of Psychoneuroendocrinology(ISPNE), Dresden (poster)
Mühlhan, M.Weerda, R., Wolf, O.T., Thiel, C.M. (2008). Effects of psychosocial stress on neural correlates of selective attention. International Congress of Psychology (ICP), Berlin. (poster)