Validation Work in the Veterans Aging Cohort Study

HIV Status in EMR

Development and verification of a "virtual" cohort using the National VA Health Information System.Fultz SL, Skanderson M, Mole LA, Gandhi N, Bryant K, Crystal S, Justice AC.Med Care. 2006 Aug;44(8 Suppl 2):S25-30.PMID:16849965

Veterans Aging Cohort Study (VACS): Overview and description.

Justice AC, Dombrowski E, Conigliaro J, Fultz SL, Gibson D, Madenwald T, Goulet J, Simberkoff M, Butt AA, Rimland D, Rodriguez-Barradas MC, Gibert CL, Oursler KA, Brown S, Leaf DA, Goetz MB, Bryant K.Med Care. 2006 Aug;44(8 Suppl 2):S13-24.

Timing and Content of Antiretroviral Therapy in EMR

Validation of an algorithm to identify antiretroviral-naïve status at time of entry into a large, observational cohort of HIV-infected patients.Gandhi NR, Tate JP, Rodriguez-Barradas MC, Rimland D, Goetz MB, Gibert C, Brown ST, Mattocks K, Justice AC.Pharmacoepidemiol Drug Saf. 2013 Sep;22(9):1019-25. doi: 10.1002/pds.3476. Epub 2013 Jul 9

Does an index composed of clinical data reflect effects of inflammation, coagulation, and monocyte activation on mortality among those aging with HIV?Justice AC, Freiberg MS, Tracy R, Kuller L, Tate JP, Goetz MB, Fiellin DA, Vanasse GJ, Butt AA, Rodriguez-Barradas MC, Gibert C, Oursler KA, Deeks SG, Bryant K; VACS Project Team.Clin Infect Dis. 2012 Apr;54(7):984-94. doi: 10.1093/cid/cir989. Epub 2012 Feb 15.

Fill/refill Adherence Measures

Measuring Persistence to Oral Hypoglycemic Agents in Type 2 Diabetic Veterans.

Kim N, Agostini J, Justice A.J Pharm Technol. 2009 Jul;25(4):223-229.

Refill adherence to oral hypoglycemic agents and glycemic control in veterans.

Kim N, Agostini JV, Justice AC.Ann Pharmacother. 2010 May;44(5):800-8. doi: 10.1345/aph.1M570. Epub 2010 Apr 13

Validation of ICD-9 Diagnostic Codes, Lab Data and Meds for Comorbid Disease

Medical disease and alcohol use among veterans with human immunodeficiency infection: A comparison of disease measurement strategies.Justice AC, Lasky E, McGinnis KA, Skanderson M, Conigliaro J, Fultz SL, Crothers K, Rabeneck L, Rodriguez-Barradas M, Weissman SB, Bryant K; VACS 3 Project Team.Med Care. 2006 Aug;44(8 Suppl 2):S52-60.PMID:16849969

The need for validation of large administrative databases: Veterans Health Administration ICD-9CM coding of exudative age-related macular degeneration and ranibizumabusage.Latkany P, Duggal M, Goulet J, Paek H, Rambo M, Palmisano P, Levin W, Erdos J, Justice A, Brandt C.J OculBiol Dis Infor. 2010 Jul 9;3(1):30-4. doi: 10.1007/s12177-010-9052-4

Validity of diagnostic codes and liver-related laboratory abnormalities to identify hepatic decompensation events in the Veterans Aging Cohort Study.Lo Re V 3rd, Lim JK, Goetz MB, Tate J, Bathulapalli H, Klein MB, Rimland D, Rodriguez-Barradas MC, Butt AA, Gibert CL, Brown ST, Kidwai F, Brandt C, Dorey-Stein Z, Reddy KR, Justice AC.Pharmacoepidemiol Drug Saf. 2011 Jul;20(7):689-99. doi: 10.1002/pds.2148. Epub 2011 May 27.

HIV infection and the risk of diabetes mellitus.Butt AA, McGinnis K, Rodriguez-Barradas MC, Crystal S, Simberkoff M, Goetz MB, Leaf D, Justice AC; Veterans Aging Cohort Study.AIDS. 2009 Jun 19;23(10):1227-34. doi: 10.1097/QAD.0b013e32832bd7af

FIB-4 index is associated with hepatocellular carcinoma risk in HIV-infected patients.

Park LS, Tate JP, Justice AC, Lo Re V 3rd, Lim JK, Bräu N, Brown ST, Butt AA, Gibert C, Goetz MB, Rimland D, Rodriguez-Barradas MC, Dubrow R.

Cancer Epidemiol Biomarkers Prev. 2011 Dec;20(12):2512-7. doi: 10.1158/1055-9965.EPI-11-0582. Epub 2011 Oct 25.

Validation of Pain Scores in EMR

Agreement between electronic medical record-based and self-administered pain numeric rating scale: clinical and research implications.Goulet JL, Brandt C, Crystal S, Fiellin DA, Gibert C, Gordon AJ, Kerns RD, Maisto S, Justice AC.Med Care. 2013 Mar;51(3):245-50. doi: 10.1097/MLR.0b013e318277f1ad.

Validation of EMR Based Quality of Care Metrics

Measuring performance directly using the veterans health administration electronic medical record: a comparison with external peer review.Goulet JL, Erdos J, Kancir S, Levin FL, Wright SM, Daniels SM, Nilan L, Justice AC.Med Care. 2007 Jan;45(1):73-9.PMID:17279023

Validation of Alcohol Measures in EMR

Comparing alcohol screening measures among HIV-infected and -uninfected men.

McGinnis KA, Justice AC, Kraemer KL, Saitz R, Bryant KJ, Fiellin DA.

Alcohol ClinExp Res. 2013 Mar;37(3):435-42. doi: 10.1111/j.1530-0277.2012.01937.x. Epub 2012 Oct 10.PMID:23050632

Smoking Measures

Decreased awareness of current smoking among health care providers of HIV-positive compared to HIV-negative veterans.Crothers K, Goulet JL, Rodriguez-Barradas MC, Gibert CL, Butt AA, Braithwaite RS, Peck R, Justice AC.

J Gen Intern Med. 2007 Jun;22(6):749-54. Epub 2007 Mar 1.

Validating smoking data from the Veteran's Affairs Health Factors dataset, an electronic data source.McGinnis KA, Brandt CA, Skanderson M, Justice AC, Shahrir S, Butt AA, Brown ST, Freiberg MS, Gibert CL, Goetz MB, Kim JW, Pisani MA, Rimland D, Rodriguez-Barradas MC, Sico JJ, Tindle HA, Crothers K.

Nicotine Tob Res. 2011 Dec;13(12):1233-9. doi: 10.1093/ntr/ntr206. Epub 2011 Sep 12

Other Validations Possibly of Interest

Comparison of two VA laboratory data repositories indicates that missing data vary despite originating from the same source.McGinnis KA, Skanderson M, Levin FL, Brandt C, Erdos J, Justice AC.Med Care. 2009 Jan;47(1):121-4. doi: 10.1097/MLR.0b013e31817d69c2.

Collection of socially sensitive data: A randomized study comparing the advantages and limitations of self administered questionnaire on computer vs. traditional paper based method.Duggal M, Justice AC, Ananth G, Brandt C.AMIA AnnuSymp Proc. 2007 Oct 11:946