Press Release
Leica Microsystems AG
Wilfried SauerErnst-Leitz-Straße 17-37
Tel. +49 (0)64 41/29-2550, Fax +49 (0)64 41/29-2527D-35578 Wetzlar
Press Release
11th October 11, 2007
The perfect imaging solutionstart for scientificresearch research microscopy
Leica DMI3000 B – the manual,universal, invertedse, universal microscope for live cell imaging
WETZLAR, GERMANY. Leica Microsystems presentsWith the new generation Leica DMI3000B generation,Leica Microsystems is now presenting an invertedse microscope,specifically designedthat is specially suited for live cell research applications in living cell research. The technology and convenience of the Leica DMI3000B offers convenience and configuration possibilities that are unparalleled in this class of manual microscopeunique features in its class. Leica’sThe newly, integrated incident- light fluorescence axis produces brilliant images for all manual fluorescence techniques. As a result, tThe Leica DMI3000 Bis microscopealso offers the user even morepossibilities than its already very successful previous model. The solutions developed by Leica Microsystems for integrated modulation and phase contrast methods that do not require the use of any special objectivess. The system can also be configured with extreme flexibility. The additional manual fluorescence enables the Leica DMI3000B to be implemented universally as a microscope for live cell imaging - and offers the perfect start for research microscopy.
Image bBrilliance and system flexibilitydiversityforwith transmitted light and fluorescence applications
The new Leica DMI3000 B is idealcan be implemented for all manual fluorescence techniques. The system features a. The 5-positionfold fluorescence turret provides space for the fluorescenceproven Leica filter cubes. Color or neutral illumination, GFP application or immunofluorescence - all these possibilities can be integrated quickly and simply using a fluorescence insert.Leica’sThe Fluorescence Intensity Manager (FIM) regulates the illuminationnce, as well as the aperture and field diaphragm and their centering. The fluorescence cubes feature with light traps for background light reduction, to produce a perfectly black background.
TFor transmitted-light applications the Leica DMI3000B offers the a greatest variety ever of illumination supports with the most varying degrees of illuminanceoptions for transmitted light applications. The large selection of condensers has been supplemented by a special S40 condensor for micromanipulation with a working distance of 40 mm, which is also suitable for the Integrated Phase Contrast (IPH) and the Integrated Modulation Contrast (IMC). Leica has improved itsThe IMC has meanwhile also been improved even further to increase the depth of field, which increases the spatial visibility of, with the result that thicker specimens can become spatially visible due to an increased depth of field. With the S40, Leica now offers there is now a total of five different condensers available with different working distances (1, 23, 28, 40, and 70 mm). The Differential Interference Contrast (Differential Interference Contrast (DIC)) is also possible with the S70 condensor, as for the previous model. For the budgetprice-conscious user, a transmitted- light arm is available with an integrated 30W lamp houseing. This rounds off the Leica range of illumination arms with replaceable lamp housings.
Flexible system solution: y combineablea variety of components and accessories
MicromanipulationApplications for micromanipulation demand requires a meticulouslyvery carefully aligned microscope system. For this purpose, Leica Microsystems offers a variety ofdifferentmicromanipulators,,; e.g., mechanical, electrical, and or hydraulic micromanipulators ,; that work seamlesslyare withoptimally matched to the Leica DMI3000B. A special stage for easysimple handling of the manipulators, and a variety of condensers with different working distances configure the DMI3000 B as a complete micromanipulation systemsupplement the system.
Integrated Modulation Contrast (The Integrated Modulation Contrast (IMC)) is ideal for non-colored, low-contrast specimens. LeicaBy integratesing the modulator outside of the objectivein the optical path – a Leica Microsystems innovation –, a this method that is considerably easier to manage and more flexible in its application. Instead of special objectives, a variety oflarge number of bright field or phase objectives can be usedcan be implemented. Via the freely accessible modulators, the image impression can now be modified optimized for cindividually for the first time. Contrast, resolution, depth of field, and relief impression can be adjusted optimally to best view ththe specimen.
To create ideal climateic conditions for while examining livieng specimens, Leica offers a variety of incubators, temperature sensors, and heatable microscope stages can be used, for example. The Leica BL Incubator consists of aone single climateic chamber that fully integratesharmonizes completely wit with all the components, such as micromanipulators, scanning stages or cross-stages.
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Leica Microsystems is a leading global designer and producer of innovative, high-tech, precision optical systems for the analysis of microstructures. It is one of the market leaders in each of its business areas: Microscopy, Confocal Laser Scanning Microscopy with corresponding Imaging Systems, Specimen Preparation, and Medical Equipment. The company manufactures a broad range of products for numerous applications requiring microscopic imaging, measurement, and analysis. It also offers system solutions for life science including biotechnology and medicine, research and development of raw materials, and industrial quality assurance. The company is represented in over 100 countries with 7 manufacturing facilities in 5 countries, sales and service organizations in 20 countries and an international network of dealers. With its workforce of about 3,050 employees it made a turnover of US$651m in 2006. The international management is headquartered in Wetzlar, Germany.Leica Microsystems is a leading global designer and producer of innovative, high-tech, precision optical systems for the analysis of microstructures. It is one of the market leaders in each of its business areas: Microscopy, Confocal Laser Scanning Microscopy with corresponding Imaging Systems, Specimen Preparation, and Medical Equipment. The company manufactures a broad range of products for numerous applications requiring microscopic imaging, measurement, and analysis. It also offers system solutions for life science including biotechnology and medicine, research and development of raw materials, and industrial quality assurance. The company is represented in over 100 countries with 7 manufacturing facilities in 5 countries, sales and service organizations in 20 countries and an international network of dealers. With its workforce of about 3,050 employees it made a turnover of US$651m in 2006. The international management is headquartered in Wetzlar, Germany.
Leica Microsystems is a leading global designer and producer of innovative, high-tech, precision optical systems for the analysis of microstructures. It is one of the market leaders in each of its business areas: Microscopy, Confocal Laser Scanning Microscopy with corresponding Imaging Systems, Specimen Preparation, and Medical Equipment. The company manufactures a broad range of products for numerous applications requiring microscopic imaging, measurement, and analysis. It also offers system solutions for life science including biotechnology and medicine, research and development of raw materials, and industrial quality assurance. The company is represented in over 100 countries with 7 manufacturing facilities in 5 countries, sales and service organizations in 20 countries and an international network of dealers. With its workforce of about 3,050 employees it made a turnover of US$651m in 2006. The international management is headquartered in Wetzlar, Germany.
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