I. Program objective:
The incidence of breast cancer has increased significantly since the early 1940’s such that 1 in 8 women now can expect to be diagnosed with breast cancer in their lifetime. Approximately 40,000 women in the U.S. will die this year of breast cancer. The inability to account for this increase in breast cancer incidence with known risk factors such as diet and exercise, and the cumulative findings of hundreds of epidemiological studies, suggest that exposure to environmental pollutants contributes to breast cancer. The primary mission of the Art beCAUSE Breast Cancer Foundation is to fund research dedicated to identifying these putative environmental causes of breast cancer. A secondary goal is to provide support to highly talented breast cancer researchers in the early stages of their careers in order to motivate their development into outstanding breast cancer scientists.
II. Award description
The Art beCAUSE Breast Cancer Foundation has developed a “Seed a Scientist” program to supply seed money to support research by those investigating environmental etiologies of breast cancer. A two year award of up to $60,000 (including up to 10% indirect costs) will be made at $30,000 per year. Applicants should be accomplished in research relating to breast cancer and the environment and show significant potential to develop into an outstanding scientist in this area. As detailed below in “Format”, the grant should summarize previous work, goals for future research, and how this seed grant could lead to subsequent funding to
further research efforts. The total length of the format sections IV E through IV I, including figures, may not exceed 5 pages, excluding references. Awardees will agree to attend the Foundation’s annual fund-raising event in Boston, Massachusetts on October 16, 2014 to accept the award and to speak briefly about how the award will help them in their research, and to attend conferences, events, etc. sponsored by the Foundation and which reasonably fit into their schedule. Every six months, Awardees are expected to provide a progress report on the research funded by the Seed the Scientist grant.
Applications are reviewed by a panel of scientists, physicians, and breast cancer research advocates with significant expertise in laboratory- and community-based studies.
Applications are due August 15, 2014. Awards are announced September 19, 2014
For additional information contact: Ellie Anbinder ,
Completed applications should be sent electronically to and a copy mailed to:
Nicole Longwell
c/o: Art beCAUSE Breast Cancer Foundation P.O.BOX 3025
Framingham, MA 01705-3025
III. Eligibility
The applicant should have an M.D., Ph.D., and/or MPH degree or must anticipate completing the requirements for one of these degrees within 2 years of receiving an award from Art BeCAUSE. All awardees must be within 10 years of their terminal degree. For junior scientists and pre-doctoral fellows, mentorship from senior investigators is encouraged and, when appropriate, should be indicated by a letter of support from the sponsor/mentor. Candidates for this award must exhibit a commitment to breast cancer research.
1
IV. Format
A. Grant Application Face page (Last page): All sections must be in 11 point, Arial font with a minimum of 0.5 inch margins. The face page template provided in this package should be used. Please indicate if IRB or IACUC applications are pending.
B. Budget Year 1 and Year 2 (Page 2- 3): The template provided as page #2 should be used. Allowed expenses include salaries, supplies, and small equipment (under $1000). Indirect costs of up to 10% of the requested direct costs are allowed. The total budget cannot exceed $30,000/year. A no-cost extension is permitted following approval by the Art beCAUSE Breast Cancer Foundation Board.
C. Scientific Abstract (Page 4): The template provided as page #3 should be used. The scientific abstract should not exceed 500 words.
D. Lay Abstract (Page 5): The template provided as page #4 should be used. The lay abstract should not exceed 500 words.
E. Background: Summarize the relationship of the work to breast cancer and the environment. Provide sufficient information to put the proposed work into the context of breast cancer prevention, incidence, progression, prognosis, or treatment.
F. Specific aim(s): List specific aims with enough detail to provide reviewers with an overview of how the experimental problem will be approached and of the potential impact of expected results.
G. Preliminary/Previous Work: Describe previous work with references where appropriate. Pilot studies designed to break new ground need not be accompanied by extensive preliminary or previous data. However, sufficient rationale should be provided to enable reviewers to assess the likelihood of success and the potential impact of results obtained as described in the proposal.
H. Experimental design: Describe the experimental plan in detail. Discuss possible outcomes and potential pitfalls. Detail the role of senior mentors in the experimental design or in providing experimental support.
I. Potential for future funding: Explain how the information obtained from this study, together with studies funded by other sources could help provide key information to position the applicant for future funding.
J. References: References should be cited in a numbered sequence in the text. There is no page limit for the references section.
K. Biosketch (Page 6): Use the template provided in this package to provide background information on the applicant and other important contributors including collaborators and senior mentors.
Sections E-I, including figures but excluding references, should not exceed 5 pages.
Principal Investigator
BUDGET Year 1 / FROM / THROUGHPERSONNEL / Months Devoted to Project / INST.BASE SALARY / DOLLAR AMOUNT REQUESTED
NAME / ROLE ON PROJECT / Cal. Months / Acad. Months / Summer Months / SALARY REQUESTED / FRINGE BENEFITS / TOTAL
PI
SUBTOTALS
SUPPLIES (Itemize by category)
OTHER EXPENSES (Itemize by category)
SUBTOTAL DIRECT COSTS / $
Subtotal Indirect Costs (10% of direct costs maximum)
TOTAL COSTS / $
Principal Investigator
BUDGET Year 2 / FROM / THROUGHPERSONNEL / Months Devoted to Project / INST.BASE SALARY / DOLLAR AMOUNT REQUESTED
NAME / ROLE ON PROJECT / Cal. Months / Acad. Months / Summer Months / SALARY REQUESTED / FRINGE BENEFITS / TOTAL
PI
SUBTOTALS
SUPPLIES (Itemize by category)
OTHER EXPENSES (Itemize by category)
SUBTOTAL DIRECT COSTS / $
Subtotal Indirect Costs (10% of direct costs maximum)
TOTAL COSTS / $
Principal Investigator:
Scientific Abstract (500 words):
Principal Investigator:
Lay Abstract (500 words):
I. BIOGRAPHICAL SKETCH
Provide the following information for the principle investigator, key personnel, and other significant contributors. Follow this format for each person.
Do not exceed 4 pages.
NAME POSITION TITLE
EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.)
INSTITUTION AND LOCATION / DEGREE(if applicable) / YEAR(s) / FIELD OF STUDY
Professional Experience: Advisory:
Publications: Other:
Art beCAUSE Breast Cancer Foundation (http://www.artbecause.org
Grant Application: "Seed the Scientist"
1. TITLE OF PROJECT2. PRINCIPAL INVESTIGATOR
3a. NAME (Last, first, middle) / 3b. DEGREE(S)
3c. POSITION TITLE / 3d. MAILING ADDRESS (Street, city, state, zip code)
E-MAIL ADDRESS:
3e. DEPARTMENT, SERVICE, LABORATORY, OR EQUIVALENT
3f. MAJOR SUBDIVISION
3g. TELEPHONE AND FAX (Area code, number and extension)
TEL.: FAX:
4. HUMAN
SUBJECTS / 4a. If "Yes," Exemption no.
or / 5. VERTEBRATE
ANIMALS / 5a. If "Yes," 5b. Animal welfare IACUC approval date assurance no.
No
Yes / IRB approval date / Full IRB or
Expedited Review / No
Yes
4. DATES OF PROPOSED PERIOD OF
SUPPORT (month, day, year--MM/DD/YY) / 5. COSTS REQUESTED
BUDGET PERIOD
From / Through / 5a. Direct Costs ($) / 5b. Total Costs ($)
6. APPLICANT ORGANIZATION
Name Address
7. ADMINISTRATIVE OFFICIAL TO BE NOTIFIED IF AWARD IS MADE
Name Title Address
Telephone FAX
E-Mail / 8. OFFICIAL SIGNING FOR APPLICANT ORGANIZATION
Name Title Address
Telephone FAX
9. Signature of Principal investigator / 10. Date
11 Signature of institutional official / 12. Date
Face Page