Supplementary Table 1.Univariate and Multivariate Cox Hazards Analyses for Overall Survivalin the 43 Glioblastoma Patients

Variable / Univariate / Multivariate
P / HR / 95% CI / P / HR / 95% CI
Sex / 0.335 / 0.732 / 0.388-1.380 / - / - / -
Age / 0.011 / 1.036 / 1.008-1.065 / 0.350 / 1.018 / 0.981-1.055
Tumor Size (FLAIR) / 0.955 / 1.000 / 0.998-1.002 / - / - / -
Tumor Size (CEL) / 0.536 / 1.003 / 0.994-1.011 / - / - / -
LV contacting CEL / 0.530 / 1.223 / 0.653-2.292 / - / - / -
Resection / 0.974 / 1.007 / 0.663-1.529 / - / - / -
Pre-operative KPS / <0.001 / 0.929 / 0.901-0.957 / <0.001 / 0.908 / 0.870-0.948
IDH1 mutation / 0.006 / 0.183 / 0.054-0.619 / 0.001 / 0.089 / 0.023-0.352
MGMT methylation / <0.001 / 0.236 / 0.110-0.503 / <0.001 / 0.143 / 0.050-0.406

CEL: contrast-enhancing lesions; FLAIR:fluid-attenuated inversion-recovery; IDH1: isocitrate dehydrogenase 1; KPS:Karnofsky Performance

Scores; LV: lateral ventricle; MGMT: O(6)-methylguanine-DNA-methyltransferase

Supplementary Table 2.Univariate and Multivariate Cox Hazards Analyses for Progress-free Survivalin the 43 Glioblastoma Patients

Variable / Univariate / Multivariate
P / HR / 95% CI / P / HR / 95% CI
Sex / 0.565 / 0.829 / 0.437-1.571 / - / - / -
Age / 0.166 / 1.018 / 0.993-1.043 / - / - / -
Tumor Size (FLAIR) / 0.881 / 1.000 / 0.997-1.002 / - / - / -
Tumor Size (CEL) / 0.614 / 0.998 / 0.988-1.007 / - / - / -
LV contacting CEL / 0.873 / 1.053 / 0.559-1.982 / - / - / -
Resection / 0.764 / 0.938 / 0.6161.427 / - / - / -
Pre-operative KPS / 0.002 / 0.956 / 0.929-0.984 / 0.030 / 0.964 / 0.932-0.996
IDH1 mutation / 0.007 / 0.189 / 0.056-0.639 / 0.022 / 0.240 / 0.071-0.816
MGMT methylation / 0.006 / 0.385 / 0.195-0.760 / 0.007 / 0.361 / 0.173-0.753

CEL: contrast-enhancing lesions; FLAIR:fluid-attenuated inversion-recovery; IDH1: isocitrate dehydrogenase 1; KPS:Karnofsky Performance

Scores; LV: lateral ventricle; MGMT: O(6)-methylguanine-DNA-methyltransferase