21

A.D. Keegan

CURRICULUM VITAE

Achsah Dorsey Keegan, Ph.D.

Professor of Microbiology and Immunology

Program in Oncology

Marlene and Stewart Greenebaum Cancer Center

Center for Vascular and Inflammatory Diseases

Date: 6-30-14

Office Address: University of Maryland School of Medicine

Center for Vascular and Inflammatory Diseases

800 W. Baltimore St., Rm 318

Baltimore, MD 21201

(410) 706-8174

(410) 706-8234 fax

Education: B.S. Zoology, (Magna Cum Laude)

Duke University, 1983

Ph.D. Immunology (Molecular Biology and Genetics)

Johns Hopkins University School of Medicine, 1989

Advisor: Dr. Daniel H. Conrad

Post-graduate

Education:

1989-1994 Post-doctoral research as National Research Council Associate and NIAID Staff Fellow, Laboratory of Immunology, NIAID, NIH

Advisor: Dr. William E. Paul

Employment

History:

1994-1999 Scientist I, Department of Immunology, Jerome H. Holland Laboratory,

American Red Cross, 15601 Crabbs Branch Way, Rockville, MD 20855

1996-2001 Assistant Professor of Microbiology and Immunology, George Washington University Medical Center (GWUMC), Washington, D.C.

1996-2007 Member of the Institute for Biomedical Sciences, GWUMC, Graduate Program in Molecular and Cellular Oncology, Program in Immunology

1999-2002 Scientist II, Department of Immunology, Jerome H. Holland Laboratory

2000-2004 Deputy Head, Department of Immunology, Holland Laboratory

2001-2004 Associate Professor of Immunology with tenure, GWUMC

2001-2004 Director, Graduate Program in Immunology, the Institute for Biomedical Sciences, GWUMC

2002-2004 Senior Scientist, Department of Immunology, Jerome H. Holland Laboratory

2004-present Professor (with tenure) of Microbiology and Immunology

Program in Oncology, Marlene and Stewart Greenebaum Cancer Center, University of Maryland, School of Medicine, Baltimore, MD

2004-2012 Adjunct Professor of Microbiology, Immunology, and Tropical Medicine, GWUMC

2005-present Program Leader, Immunity and Inflammation, Center for Vascular and Inflammatory Diseases, University of Maryland, School of Medicine

2005-present Member, Graduate Program in Life Sciences (GPILS), University of Maryland School of Medicine, Program in Molecular Microbiology and Immunology, and Program in Molecular Medicine

2012-present Associate Director, Medical Scientist Training Program, University of Maryland, School of Medicine

2013-present VA Health Research Scientist, Baltimore VA Medical Center

Professional

Memberships:

American Association of Immunologists, since 1990

ASBMB, since 2003

International Society for Interferon and Cytokine Research, since 2004

International Cytokine Society, since 2005

Society for Leukocyte Biology, since 2010

Honors and Awards:

Cum laude Society, Queen Anne School, 1979

Daughter's of the Cincinnatti Scholarship, 1979-1981

Duke University, Grant-in aid, 1979-1981

Phi Eta Sigma, Duke University, 1980

Phi Beta Kappa, Duke University, 1983

Dean's List and Class Honors, 1980-1983

National Research Council Associate, (1989-92)

American Red Cross, "On-the-spot" Merit Award, 1996

Tiffany Award for Excellence in Management, 2004

Teaching Commendation-HDID-Immunology, 2006

Administrative

Service:

Institutional: Holland Laboratory, American Red Cross

Library Committee: 1994-1997, Chair 96-97.

Seminar Series: Immunoregulation, 1995

Regulation of Hematopoiesis by Cytokines, 1997

Signaling in the Immune System, 2004

Search Committee: Immunology Department, 1996, 1998, 2002

Molecular Biology Department, 1997

IACUC: 2001-2004

Presentation, Fogarty Center Fellows in Blood Safety, July 01, 02

George Washington University and GWIBS

Thesis Committee:

Dubravka Donjerkovic, MCOP, 1997-1999

Robert McKallip, MCOP, 1999

Sheila Caldwell, MCOP, 1999-2001

Mary Litzinger, IMM, 2000-2004

Jodi Camberg, Biochem, 2004

Sun Park, Genetics, 2004

William Gwinn, IMM, 2003-2007

Yan Su, IMM, 2004-2007

Examination Committee:

Jennifer Hinshaw, 1999

Jennifer Mariner, 1999

Samantha Soldin, 1999

Michael Petrus, 2002

Mary Beth Daucher, 2002

Steering Committee, Program in Immunology, GWIBS, 1997-1999

Admission Committee, 1997-1999.

Mission and Goals Committee, Dept. of Micro and Immunol, 1998

Search Committee, Dept. of Immunology, GWUMC, 2000

Operations Committee, GWIBS, 2000-2004

Director, Graduate Program in Immunology, 2001-2004

Executive Committee, GWIBS, 2004

UNIVERSITY OF MARYLAND, BALTIMORE

Graduate Student Advisor:

Deepa Rajagopal, Micro and Immuno, 2005

Aakanksha Pant, Micro and Immuno, 2005

Yanchun Li, 2006-2007 (MM, Cancer Biology)

Teresa Hsi, Micro and Immuno, 2008

Carolyn Morris, MMI, 2009-2011

Brigit Quinn, MMI, 2012-2014

Rotation Advisor: Minjun Yu, MMI, 2005

Holly Porter, Mol Med, 2006

Preeta Dasgupta, MMI, 2007

Nicolas Johnson, MD/PhD, MMI, 2008

Stephanie Lehman, MMI, 2014

Oral Examination

Committee: Smita Chandran, 2006 (MMI)

Lynn Li (Chair), 2006 (MM, Cancer Biology)

Kristina Harris, 2006 (MM, Physiology)

Michele Weiss (Chair), 2007 (MM, Cancer Biology)

Yoni Skupsky, 2007 (MM, Physiology)

Limei Lin (Chair), 2007 (MM, Cancer Biology)

Steven Bowen, 2008 (MMI)

Mark Marohn, 2008 (MMI)

Patrick Hagner (Chair), 2008 (MM, Cancer Biology)

Zhongping Liao (Chair), 2008 (MM, Cancer Biology)

Kaushal Asrani (Chair), 2008 (MM, Cancer Biology)

Kathryn Hodge (Chair), 2009 (MM, Cancer Biology)

Michelle Sallin (Chair), 2009 (MM, Cancer Biology)

Amanda Boggs, (Chair), 2010 (MM, Cancer Biology)

Jessica Bennett, (Chair), 2010 (MM, Cancer Biology)

Rex Sun, (Chair), 2010 (MM, Physiology)

Tiha Long, 2011 (MM, Cancer Biology)

Sarah Horvat, 2011 (MM, Physiology)

Drew Roberts, 2011 (MM, Cancer Biology)

Jennifer Fox, 2012 (MM, Cancer Biology)

Gloria Serena, 2013 (MM, Physiology)

Irina Tiper, 2013 (MM, Cancer Biology)

Greg Conway, 2014 (MM, Cancer Biology)

Haley Simpson, 2014 (MM, Cancer Biology)

Thesis Committee:

Nick Bushar, (Reader, Graduate School Rep) MMI, 2005-09

Michelle Weber Laird (Reader), MMI, 2005-09

Smita Chandran, (Reader) MMI, 2007-09

Ranjani Prabakhara, (Reader, Graduate School Rep) MMI, 07-09

Limei Lin, (Graduate School Rep) MM, Cancer Biology, 2007-09

Bhavik Desai, Biomedical Sciences, Dental, 2007-08

Yoni Skupsky, (Reader, Graduate School Rep) MSTP, MM, Physiology, 2007-2009

Lani Lorenzo, (Reader) MMI, 2007-2011

Kristen Burdette, MMI, (Reader) 2008-2012

Nathaniel Noyes, MM, Physiology, 2010-2014

Nate Archer, MMI, (Reader) 2010-2013

Julie B. Craig, MSTP, MM, Physiology, (Reader, Graduate School Rep) 2010-2013

Carly Page, MMI, (Reader) 2010-2012

Jessica Shiu, MSTP, MMI, (Reader, Graduate School Rep) 2010-2013

Rex Sun, MM, Physiology, 2011-present

Sarah Horvat, MM, Physiology, 2011-2014

Drew Roberts, MM, Cancer Biology, 2012-present

Patrick Adair, MM, Physiology, 2012-present

Aaron Christenson-Quick, MMI, 2012-present

Christina Young, Biochemistry, 2013-present

Irina Tiper, MM, Cancer Biology, 2013-present

Experimental Therapeutics Retreat Committee, 2005

Admission Committee, Molecular Microbiology and Immunology, GPILS, 2005-2007

Core Advisory Committee, Cancer Biology, Molecular Medicine, GPILS, 2006-2012

Qualifying Exam Coordinator, Cancer Biology, Molecular Medicine, GPILS, 2007-

2011

Search Committee, Dept. of Surgery (Transplantation), UMB, 2006-2007

Faculty Reviewer, Center for Vascular and Inflammatory Diseases Research in Progress,

2007- present

GPILS Awards Committee, 2007-2008

Chair, GPILS Awards Committee, 2008

Appointment, Promotions, and Tenure Committee, 2007-2011

Subcommittee on Evaluation Guidelines for Non-Traditional Candidates, 2008

Representative of APT Committee Presentation to WIMS, 2009

Chair, Appointment, Promotions, and Tenure Committee, 2009-2011: Presentations:

Department of Anesthesiology Retreat, September 12, 2009

New Faculty Orientation, October 8, 2009

Department of Epidemiology APT Committee, September 9, 2010

New Faculty Orientation, October 7, 2010

Department of Epidemiology Faculty Presentation, November 18, 2010

K-Scholars Symposium, April 15, 2011

Women in Medicine and Science (WIMS), 2008- present

Internal Scientific Advisory Panel, Program Project Grant entitled, "Protease Functions in

Intestinal Mucosal Pathobiology". Drs. Fasano, Antalis, Vogel, and Shea- Donohue, 2007-2009

Steering Committee, T32 Training Program in Molecular and Cellular Immunology,

2007-2009

Advisory Committee, T32 Training Program in Vascular Biology,

2009-present

Co-organizer of the Goidl/Grollman Symposium (May 11, 2010), UMB 2010.

Co-Director, T32 Training Program in Signaling Pathways in Innate Immunity,

2010-present

Member, Department of Microbiology and Immunology Appointment, Promotions, and Tenure Committee, 2011-present

REAP Program Coordinator, Center for Vascular and Inflammatory Diseases, 2012-

2014

Faculty Scientific Advisory Committee for Health Sciences Facility III, 2012 – present

Education Resource Advisory Group: Vision 2020, 2013-present

Local:

Invited guest, Women in Science Club, Walt Whitman High School, 1995

Study section for the American Heart Association, Maryland affiliate; 1996-1999.

Presentation, Montgomery County High School Teachers, 1997, 1999

Science Fair Judge, Stone Ridge School, 2000-2002

Guest Lecturer, Frederick Ladies Book Club, Immortal Life of Henrietta Lacks; October, 2011

National:

Co-chair, Minisymposium on Cytokine Receptors, April 27, 1994, AAI meeting,

Anaheim, CA.

Co-chair, Minisymposium on Receptors and Signal Transduction I, February 23,

1997, AAI meeting, San Francisco, CA

Organizing Committee, 1997 Annual Meeting, Society for Leukocyte Biology

Chair, Workshop on Signal Transduction, December 5, 1997, Society for Leukocyte

Biology Annual National Meeting

Chair, Symposium on Cytokines, December 6, 1997, Society for Leukocyte Biology

Annual National Meeting

Focus Group, Division of Allergy, Immunology, and Transplantation, NIAID. May 4,

1998.

Co-chair, Minisymposium on IL-4 and IL-13 activated responses, Experimental Biology ‘

99, April 17, 1999, Washington , D.C.

Co-chair, Minisymposium on IL-4/IL-13, American Association of Immunologists, May

12, 2000, Seattle, WA

Chair, Novel Therapeutic Approaches to Asthma I, February 12, 2002, Keystone

Symposium 2002, Rethinking the Pathogenesis of Asthma, Santa Fe, NM.

Co-chair, Minisymposium on STATs, American Association of Immunologists, April 24,

2002, New Orleans, LA.

Invited participant, Meeting "Exploring the Integration of Psychoneuroimmunology and

Tumor Immunology in Cancer Control Research," April 15-16, 2004, Bethesda,

MD, sponsored by the National Cancer Institute.

Working Group, NOVA Television and DVD project "Immunology: A History," with

State of the Art production company, 2004-2007.

Invited participant, Research Group on the Usability of the Website for the Office

of Extramural Research, NIH, May 19, 2004, NCI Communication Technology Research Center, NIH-Usability Testing Lab, Rockville, MD.

Member, American Association of Immunologists, Education Committee, 2005-2009

Program Block Chair, American Association of Immunologists, Annual Meeting, 2007 -

2010

Co-chair, Minisymposium on Eosinophils, Mast cells, and Basophils, American Association of Immunologists, May 18, 2007, Miami, FL.

Co-chair, Minisymposium on Cytokines and Chemokines, American Association of

Immunologists, May 8-12, 2009, Seattle, WA.

Invited Faculty Member, American Association of Immunologists Introductory Course, 2010-2012.

Alternate Representative of the American Association of Immunologists to the Board of Trustees meeting of the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) International, September 24-25, 2011, Bethesda, MD.

Invited Course Moderator and Speaker, “Deeper Insights into the Mechanisms of Asthma and Allergic Inflammation,” AAAAI Annual Meeting, Orlando, FL, March 2012.

Representative of the American Association of Immunologists to the Board of Trustees of the Association for Assessment and Accreditation of Laboratory

Animal Care (AAALAC) International, 2013-present.

Co-Chair, Major Symposium, “Cytokines: In Sickness and in Health,” American

Association of Immunologists, May 2-5, 2014, Pittsburgh, PA.

Grant review

Study section for the American Heart Association, National Committee, Immunology and Microbiology II; 1998

Site visit review of Program Project Grant, NCI, 9/22/98-9/24/98, Cleveland, OH and

reporter to parent committee 12/2/98

Ad hoc reviewer for Allergy and Immunology study section. 10/22-10/23/98.

Invited member, Special Emphasis Panel, Asthma and Allergic Diseases Research

Centers, 3/10/99-3/12/99.

Chartered member. Allergy and Immunology study section, 1999-2003.

Invited member, Special Emphasis Panel, Asthma and Allergic Diseases Research

Centers, 4/10/01-4/11/01.

Chair, Special Emphasis Panel, Allergy and Immunology study section, 7/30/02

Invited member, Special Emphasis Panel, Unsolicited Program Project Grant Review,

12/17/02.

Program Project Grant Review, NCI, Teleconference review, 1/27/04

Invited member, Program Project Grant Cytokine Review Group, NCI, 9/27/04

Invited member, Special Review Panel, Centers for Medical Countermeasures Against

Radiation, NCI, 6/20-6/22/05

Invited member, International Grant Review Panel, GRIP and FIRCA, 2/9- 2/10/06

Ad hoc reviewer for CMI-A study section. 6/20-6/21/06.

Ad hoc reviewer for SBDD study section, 3/9/07-3/11/07

Invited member, Program Project Cluster Review, Grant Cytokine Review Group, NCI,

06/04-06/05/2007

Invited member, Bone Biology Special Emphasis Panel, 06/13/07

Invited member, Program Project Cluster Review, Cellular and Tissue Biology, NCI,

10/16/08

Invited member, Bone Biology (MOSS) Special Emphasis Panel, 10/22/08

Invited member, NHLBI Program Project Review Special Emphasis Panel, 01/06/09

Ad hoc reviewer for SBDD study section, 02/08/09

Chartered member. Cellular and Molecular Immunology-B, 2010-2014.

Invited reviewer for Medical Research Council, United Kingdom, 09/05/12

Invited International Reviewer for Medical Research Council, South Africa, Unit

Immunology of Infectious Diseases, 07/25/13.

Editorial Activity and Manuscript Review

Section Editor, Journal of Immunology, 2008-2012

Faculty of 1000 Biology, Immunology Faculty, Allergy and Hypersensitivity Section

2008-present

Associate Editor, Journal of Interferon and Cytokine Research, 2013-2016

Ad hoc reviews for: Cell, Immunity, Journal of Immunology (member of pool of expert reviewers), Journal of Biological Chemistry, J. Exp. Med., Blood, Proc. Natl. Acad. Sci., FASEB J., Cytokine, Molecular and Cellular Biochemistry, International Immunology, Clinical Immunology, Infection and Immunity, Journal of Interferon and Cytokine Research

Teaching Service: GWUMC

Development and Immunology (BMSC 213), 1997-2004

4 hrs/week for 20 students

Molecular and Cellular Immunology (IMM230), 1999-2004

4 hrs/week for 10 students

Director, Molecular & Cell Immunology (IMM230), 1999-02

8 hrs/week for 10 students

Director, Readings in Immunology (IMM398) 1999-2004

Director, Research in Immunology (IMM399) 2001-2004

Women in Science and Technology (GW), 1999.

Cell Biology, (BMSC212), 2002

UMB

HDID, 2005-present

6 hours, ~150 students

Teaching Commendation-Immunology 2006

Graduate Immunobiology, 2006-present

10 hours for ~20 students

GPILS Core, 2006-2008

2 hours for 35 students,

Signal Transduction, GPILS616, 2007-present

4 hours for 30 students

Current Topics in Vascular and Stem Cell Biology, GPILS690, 2007-2012, 2 hours for 35

Advanced Immunology, 2011-present

2 hours for ~8 students

Molecules to Medicine, Course Director

14 hours 8-12 students

Supervision of Trainees:

Interns

Ms. Lisa McReynolds, intern, summer 1994, graduate of Wellesly College, 00,

Attending Medical School

Mr. Jonathan Austrian, intern, summers of 1995, 96, 97, B.S. University of

Pennsylvania, 00, Attended Cornell Medical School; co-author

Ms. Paige Greenberg, intern, summer 1999, graduate of Washington University, St.

Louis, 00

Mr. William White, Nathan Schnaper Summer Intern, Marlene and Stewart Greenebaum

Cancer Center, summer 2007, graduate University of Maryland, College Park.

Ms. Sade Solola, Nathan Schnaper Summer Intern, Marlene and Stewart Greenebaum

Cancer Center, summer 2009, graduate Loyola College of Maryland.

Ms. Morgan Hawkins, REAP Scholar, CVID, summer 2013; attending Barry College in

Florida.

Mr. James D. Keegan, intern, summer 2013, graduate University of Miami, Coral

Gables, FL. Submission to FASEB Art contest, “Young Man Standing on Top of the World.”

Ms. Taylor Babin, Nathan Schnaper Summer Intern, Marlene and Stewart Greenebaum

Cancer Center, summer 2014; attending Sacred Heart University in Connecticut.

Graduate students

Ms. Erica Helm Hanson, GW graduate student, 1999-2004 (PhD); post-doctoral fellow

with Dr. Suzanne Ostrand-Rosenberg, UMBC; currently overseas

Mr. Andrew Ford, GW graduate student, 2001-2007 (PhD), post-doctoral

fellow at UMB, currently policy fellow with National Academy of Sciences.

Ms. Kristy Markos Greeneltch, GW graduate student, 2001-2004 (PhD); post-doctoral

fellow with Dr. Scott Abrams, NCI; currently scientific analyst law offices.

Ms. Jennifer Solomon (co-mentor), GW graduate student, 2001-03 (PhD); post-

doctoral fellow with Dr. Craig Walsh, UC Irvine, Scientist with Miltenyi.

Mr. Minjun Yu, GPILS, Molecular Microbiology and Immunology, 2005-2010 (PhD);

currently post-doctoral fellow with Dr. Donna Farber, Columbia University

(Arthritis Foundation Fellowship Award)

Ms. Holly Porter, GPILS, Molecular Medicine Program, 2006-2012; Meyerhoff Fellow,

received NCI F31 pre-doctoral fellowship (2010-2011), GSA research award (2012); currently pursuing Forensic Science programs.