Supplemental Table 1. SNP Details by Study

Supplemental Table 1. SNP details by study

SNP / Study / Risk
Allelea / Base Allelea / Imputed / RAFa / R2 (Imputed SNPs) / HWE (Controls)
rs10911251 / CCFR / A / C / Yes / 0.56 / 1.00
rs10911251 / Colo23 / A / C / Yes / 0.54 / 0.74
rs10911251 / DACHS1 / A / C / Yes / 0.60 / 0.76
rs10911251 / DACHS2 / A / C / Yes / 0.54 / 0.98
rs10911251 / DALS1 / A / C / Yes / 0.57 / 1.00
rs10911251 / DALS2 / A / C / Yes / 0.59 / 0.79
rs10911251 / HPFS1 / A / C / Yes / 0.56 / 0.95
rs10911251 / HRT / A / C / Yes / 0.63 / 0.73
rs10911251 / MEC / A / C / Yes / 0.57 / 0.72
rs10911251 / NHS1 / A / C / Yes / 0.56 / 1.00
rs10911251 / NHS2 / A / C / Yes / 0.57 / 1.01
rs10911251 / OFCCR / A / C / Yes / 0.49 / 0.92
rs10911251 / PHS12 / A / C / Yes / 0.59 / 0.98
rs10911251 / PLCO2 / A / C / Yes / 0.57 / 0.81
rs10911251 / VITAL / A / C / Yes / 0.58 / 0.74
rs10911251 / WHI1 / A / C / Yes / 0.56 / 1.00
rs10911251 / WHI2 / A / C / Yes / 0.58 / 0.79
rs6687758 / CCFR / G / A / No / 0.22 / 0.35
rs6687758 / Colo23 / G / A / No / 0.20 / 1.00
rs6687758 / DACHS1 / G / A / No / 0.20 / 0.60
rs6687758 / DACHS2 / G / A / No / 0.22 / 0.30
rs6687758 / DALS1 / G / A / No / 0.20 / 0.91
rs6687758 / DALS2 / G / A / No / 0.21 / 0.89
rs6687758 / HPFS1 / G / A / No / 0.18 / 1.00
rs6687758 / HRT / G / A / No / 0.16 / 0.53
rs6687758 / MEC / G / A / No / 0.19 / 0.73
rs6687758 / NHS1 / G / A / No / 0.21 / 1.00
rs6687758 / NHS2 / G / A / No / 0.21 / 0.04
rs6687758 / OFCCR / G / A / Yes / 0.20 / 1.00
rs6687758 / PHS12 / G / A / No / 0.18 / 1.00
rs6687758 / PLCO2 / G / A / No / 0.17 / 0.48
rs6687758 / VITAL / G / A / No / 0.20 / 0.04
rs6687758 / WHI1 / G / A / No / 0.20 / 0.75
rs6687758 / WHI2 / G / A / No / 0.20 / 0.62
rs6691170 / CCFR / T / G / No / 0.38 / 0.03
rs6691170 / Colo23 / T / G / Yes / 0.39 / 0.95
rs6691170 / DACHS1 / T / G / Yes / 0.39 / 0.97
rs6691170 / DACHS2 / T / G / Yes / 0.41 / 0.90
rs6691170 / DALS1 / T / G / No / 0.36 / 1.00
rs6691170 / DALS2 / T / G / Yes / 0.35 / 0.97
rs6691170 / HPFS1 / T / G / Yes / 0.36 / 1.09
rs6691170 / HRT / T / G / Yes / 0.34 / 0.99
rs6691170 / MEC / T / G / Yes / 0.35 / 0.98
rs6691170 / NHS1 / T / G / Yes / 0.36 / 0.94
rs6691170 / NHS2 / T / G / Yes / 0.39 / 1.00
rs6691170 / OFCCR / T / G / Yes / 0.35 / 0.96
rs6691170 / PHS12 / T / G / Yes / 0.37 / 0.96
rs6691170 / PLCO2 / T / G / Yes / 0.35 / 0.98
rs6691170 / VITAL / T / G / Yes / 0.36 / 1.00
rs6691170 / WHI1 / T / G / No / 0.36 / 0.54
rs6691170 / WHI2 / T / G / Yes / 0.37 / 0.96
rs11903757 / CCFR / C / T / Yes / 0.14 / 0.97
rs11903757 / Colo23 / C / T / Yes / 0.18 / 0.38
rs11903757 / DACHS1 / C / T / Yes / 0.18 / 0.35
rs11903757 / DACHS2 / C / T / Yes / 0.14 / 1.00
rs11903757 / DALS1 / C / T / Yes / 0.14 / 0.91
rs11903757 / DALS2 / C / T / Yes / 0.19 / 0.38
rs11903757 / HPFS1 / C / T / Yes / 0.12 / 0.96
rs11903757 / HRT / C / T / Yes / 0.23 / 0.37
rs11903757 / MEC / C / T / Yes / 0.20 / 0.36
rs11903757 / NHS1 / C / T / Yes / 0.15 / 0.97
rs11903757 / NHS2 / C / T / Yes / 0.11 / 1.00
rs11903757 / OFCCR / C / T / Yes / 0.15 / 1.00
rs11903757 / PHS12 / C / T / Yes / 0.15 / 0.99
rs11903757 / PLCO2 / C / T / Yes / 0.19 / 0.36
rs11903757 / VITAL / C / T / Yes / 0.18 / 0.37
rs11903757 / WHI1 / C / T / Yes / 0.15 / 0.97
rs11903757 / WHI2 / C / T / Yes / 0.20 / 0.36
rs10936599 / CCFR / C / T / No / 0.76 / 0.34
rs10936599 / Colo23 / C / T / Yes / 0.78 / 1.00
rs10936599 / DACHS1 / C / T / Yes / 0.76 / 0.94
rs10936599 / DACHS2 / C / T / No / 0.75 / 0.55
rs10936599 / DALS1 / C / T / No / 0.76 / 0.35
rs10936599 / DALS2 / C / T / Yes / 0.74 / 0.94
rs10936599 / HPFS1 / C / T / No / 0.78 / 0.56
rs10936599 / HRT / C / T / Yes / 0.77 / 0.87
rs10936599 / MEC / C / T / Yes / 0.79 / 0.95
rs10936599 / NHS1 / C / T / No / 0.77 / 0.76
rs10936599 / NHS2 / C / T / No / 0.75 / 0.70
rs10936599 / OFCCR / C / T / Yes / 0.75 / 1.00
rs10936599 / PHS12 / C / T / No / 0.77 / 0.78
rs10936599 / PLCO2 / C / T / Yes / 0.76 / 0.99
rs10936599 / VITAL / C / T / Yes / 0.77 / 0.95
rs10936599 / WHI1 / C / T / No / 0.77 / 0.67
rs10936599 / WHI2 / C / T / Yes / 0.75 / 0.95
rs647161 / CCFR / A / C / Yes / 0.66 / 0.94
rs647161 / Colo23 / A / C / Yes / 0.62 / 0.84
rs647161 / DACHS1 / A / C / Yes / 0.68 / 0.79
rs647161 / DACHS2 / A / C / Yes / 0.68 / 0.90
rs647161 / DALS1 / A / C / Yes / 0.65 / 1.00
rs647161 / DALS2 / A / C / Yes / 0.66 / 0.81
rs647161 / HPFS1 / A / C / Yes / 0.68 / 0.89
rs647161 / HRT / A / C / Yes / 0.65 / 0.82
rs647161 / MEC / A / C / Yes / 0.66 / 0.77
rs647161 / NHS1 / A / C / Yes / 0.66 / 0.91
rs647161 / NHS2 / A / C / Yes / 0.68 / 1.00
rs647161 / OFCCR / A / C / Yes / 0.69 / 0.99
rs647161 / PHS12 / A / C / Yes / 0.67 / 0.88
rs647161 / PLCO2 / A / C / Yes / 0.68 / 0.84
rs647161 / VITAL / A / C / Yes / 0.67 / 0.80
rs647161 / WHI1 / A / C / Yes / 0.68 / 0.99
rs647161 / WHI2 / A / C / Yes / 0.68 / 0.79
rs1321311 / CCFR / A / C / No / 0.24 / 0.34
rs1321311 / Colo23 / A / C / Yes / 0.25 / 0.90
rs1321311 / DACHS1 / A / C / Yes / 0.27 / 0.93
rs1321311 / DACHS2 / A / C / No / 0.22 / 0.70
rs1321311 / DALS1 / A / C / No / 0.22 / 0.02
rs1321311 / DALS2 / A / C / Yes / 0.25 / 0.94
rs1321311 / HPFS1 / A / C / Yes / 0.27 / 1.00
rs1321311 / HRT / A / C / Yes / 0.20 / 0.90
rs1321311 / MEC / A / C / Yes / 0.26 / 0.95
rs1321311 / NHS1 / A / C / No / 0.23 / 0.42
rs1321311 / NHS2 / A / C / No / 0.23 / 0.67
rs1321311 / OFCCR / A / C / Yes / 0.27 / 0.95
rs1321311 / PHS12 / A / C / No / 0.25 / 0.50
rs1321311 / PLCO2 / A / C / Yes / 0.28 / 0.94
rs1321311 / VITAL / A / C / Yes / 0.24 / 0.89
rs1321311 / WHI1 / A / C / No / 0.26 / 0.74
rs1321311 / WHI2 / A / C / Yes / 0.26 / 0.97
rs719725 / CCFR / A / C / Yes / 0.60 / 1.00
rs719725 / Colo23 / A / C / Yes / 0.57 / 0.92
rs719725 / DACHS1 / A / C / Yes / 0.63 / 0.99
rs719725 / DACHS2 / A / C / Yes / 0.60 / 1.00
rs719725 / DALS1 / A / C / Yes / 0.62 / 0.99
rs719725 / DALS2 / A / C / Yes / 0.63 / 1.00
rs719725 / HPFS1 / A / C / Yes / 0.64 / 1.00
rs719725 / HRT / A / C / Yes / 0.64 / 1.00
rs719725 / MEC / A / C / Yes / 0.62 / 0.93
rs719725 / NHS1 / A / C / Yes / 0.62 / 0.99
rs719725 / NHS2 / A / C / Yes / 0.65 / 1.00
rs719725 / OFCCR / A / C / Yes / 0.62 / 1.00
rs719725 / PHS12 / A / C / Yes / 0.61 / 0.99
rs719725 / PLCO2 / A / C / Yes / 0.63 / 1.00
rs719725 / VITAL / A / C / Yes / 0.63 / 1.00
rs719725 / WHI1 / A / C / Yes / 0.62 / 0.95
rs719725 / WHI2 / A / C / Yes / 0.61 / 0.99
rs1665650 / CCFR / T / C / Yes / 0.25 / 0.95
rs1665650 / Colo23 / T / C / Yes / 0.34 / 1.00
rs1665650 / DACHS1 / T / C / Yes / 0.26 / 0.95
rs1665650 / DACHS2 / T / C / Yes / 0.27 / 0.99
rs1665650 / DALS1 / T / C / Yes / 0.28 / 0.95
rs1665650 / DALS2 / T / C / Yes / 0.27 / 0.96
rs1665650 / HPFS1 / T / C / Yes / 0.23 / 0.91
rs1665650 / HRT / T / C / Yes / 0.29 / 1.00
rs1665650 / MEC / T / C / Yes / 0.29 / 1.00
rs1665650 / NHS1 / T / C / Yes / 0.27 / 0.97
rs1665650 / NHS2 / T / C / Yes / 0.27 / 0.95
rs1665650 / OFCCR / T / C / Yes / 0.27 / 1.00
rs1665650 / PHS12 / T / C / Yes / 0.25 / 0.99
rs1665650 / PLCO2 / T / C / Yes / 0.28 / 0.99
rs1665650 / VITAL / T / C / Yes / 0.29 / 0.95
rs1665650 / WHI1 / T / C / Yes / 0.26 / 0.96
rs1665650 / WHI2 / T / C / Yes / 0.27 / 1.00
rs3824999 / CCFR / G / T / No / 0.50 / 0.41
rs3824999 / Colo23 / G / T / Yes / 0.53 / 1.00
rs3824999 / DACHS1 / G / T / Yes / 0.51 / 0.98
rs3824999 / DACHS2 / G / T / Yes / 0.49 / 1.00
rs3824999 / DALS1 / G / T / No / 0.52 / 0.23
rs3824999 / DALS2 / G / T / Yes / 0.50 / 1.00
rs3824999 / HPFS1 / G / T / Yes / 0.51 / 0.99
rs3824999 / HRT / G / T / Yes / 0.54 / 0.97
rs3824999 / MEC / G / T / Yes / 0.52 / 1.00
rs3824999 / NHS1 / G / T / Yes / 0.50 / 1.00
rs3824999 / NHS2 / G / T / Yes / 0.54 / 0.93
rs3824999 / OFCCR / G / T / Yes / 0.48 / 1.00
rs3824999 / PHS12 / G / T / Yes / 0.51 / 0.97
rs3824999 / PLCO2 / G / T / Yes / 0.51 / 1.00
rs3824999 / VITAL / G / T / Yes / 0.49 / 0.91
rs3824999 / WHI1 / G / T / No / 0.51 / 0.65
rs3824999 / WHI2 / G / T / Yes / 0.52 / 0.97
rs3217810 / CCFR / T / C / No / 0.13 / 0.41
rs3217810 / Colo23 / T / C / Yes / 0.15 / 0.32
rs3217810 / DACHS1 / T / C / Yes / 0.17 / 0.31
rs3217810 / DACHS2 / T / C / Yes / 0.16 / 0.49
rs3217810 / DALS1 / T / C / No / 0.10 / 1.00
rs3217810 / DALS2 / T / C / Yes / 0.17 / 0.36
rs3217810 / HPFS1 / T / C / Yes / 0.16 / 0.53
rs3217810 / HRT / T / C / Yes / 0.17 / 0.31
rs3217810 / MEC / T / C / Yes / 0.17 / 0.31
rs3217810 / NHS1 / T / C / Yes / 0.17 / 0.50
rs3217810 / NHS2 / T / C / Yes / 0.17 / 0.48
rs3217810 / OFCCR / T / C / Yes / 0.16 / 0.38
rs3217810 / PHS12 / T / C / Yes / 0.17 / 0.48
rs3217810 / PLCO2 / T / C / Yes / 0.17 / 0.30
rs3217810 / VITAL / T / C / Yes / 0.18 / 0.34
rs3217810 / WHI1 / T / C / No / 0.12 / 0.80
rs3217810 / WHI2 / T / C / Yes / 0.17 / 0.30
rs7136702 / CCFR / T / C / No / 0.33 / 0.88
rs7136702 / Colo23 / T / C / Yes / 0.32 / 0.77
rs7136702 / DACHS1 / T / C / Yes / 0.30 / 0.83
rs7136702 / DACHS2 / T / C / Yes / 0.31 / 0.82
rs7136702 / DALS1 / T / C / No / 0.33 / 0.31
rs7136702 / DALS2 / T / C / Yes / 0.31 / 0.86
rs7136702 / HPFS1 / T / C / Yes / 0.30 / 0.87
rs7136702 / HRT / T / C / Yes / 0.33 / 0.77
rs7136702 / MEC / T / C / Yes / 0.34 / 0.83
rs7136702 / NHS1 / T / C / Yes / 0.33 / 0.86
rs7136702 / NHS2 / T / C / Yes / 0.33 / 0.93
rs7136702 / OFCCR / T / C / Yes / 0.33 / 1.00
rs7136702 / PHS12 / T / C / Yes / 0.31 / 0.82
rs7136702 / PLCO2 / T / C / Yes / 0.31 / 0.79
rs7136702 / VITAL / T / C / Yes / 0.29 / 0.75
rs7136702 / WHI1 / T / C / No / 0.36 / 1.00
rs7136702 / WHI2 / T / C / Yes / 0.33 / 0.79
rs11169552 / CCFR / C / T / No / 0.72 / 0.75
rs11169552 / Colo23 / C / T / No / 0.76 / 0.08
rs11169552 / DACHS1 / C / T / No / 0.74 / 0.76
rs11169552 / DACHS2 / C / T / No / 0.76 / 0.04
rs11169552 / DALS1 / C / T / No / 0.73 / 0.78
rs11169552 / DALS2 / C / T / No / 0.71 / 0.11
rs11169552 / HPFS1 / C / T / No / 0.77 / 0.85
rs11169552 / HRT / C / T / No / 0.70 / 0.28
rs11169552 / MEC / C / T / No / 0.77 / 0.29
rs11169552 / NHS1 / C / T / No / 0.74 / 0.46
rs11169552 / NHS2 / C / T / No / 0.75 / 0.32
rs11169552 / OFCCR / C / T / Yes / 0.71 / 1.00
rs11169552 / PHS12 / C / T / No / 0.73 / 0.61
rs11169552 / PLCO2 / C / T / No / 0.74 / 0.52
rs11169552 / VITAL / C / T / No / 0.70 / 0.40
rs11169552 / WHI1 / C / T / No / 0.74 / 0.15
rs11169552 / WHI2 / C / T / No / 0.74 / 0.42
rs59336 / CCFR / T / A / Yes / 0.48 / 0.97
rs59336 / Colo23 / T / A / Yes / 0.50 / 1.00
rs59336 / DACHS1 / T / A / Yes / 0.49 / 1.00
rs59336 / DACHS2 / T / A / Yes / 0.45 / 1.00
rs59336 / DALS1 / T / A / Yes / 0.47 / 0.86
rs59336 / DALS2 / T / A / Yes / 0.47 / 1.00
rs59336 / HPFS1 / T / A / Yes / 0.47 / 1.00
rs59336 / HRT / T / A / Yes / 0.44 / 0.91
rs59336 / MEC / T / A / Yes / 0.49 / 0.99
rs59336 / NHS1 / T / A / Yes / 0.48 / 0.98
rs59336 / NHS2 / T / A / Yes / 0.49 / 1.00
rs59336 / OFCCR / T / A / Yes / 0.48 / 0.86
rs59336 / PHS12 / T / A / Yes / 0.49 / 1.00
rs59336 / PLCO2 / T / A / Yes / 0.50 / 0.99
rs59336 / VITAL / T / A / Yes / 0.42 / 0.24
rs59336 / WHI1 / T / A / Yes / 0.46 / 0.98
rs59336 / WHI2 / T / A / Yes / 0.51 / 0.96
rs2423279 / CCFR / C / T / No / 0.26 / 0.15
rs2423279 / Colo23 / C / T / No / 0.29 / 0.28
rs2423279 / DACHS1 / C / T / No / 0.27 / 0.30
rs2423279 / DACHS2 / C / T / Yes / 0.25 / 1.00
rs2423279 / DALS1 / C / T / Yes / 0.25 / 0.99
rs2423279 / DALS2 / C / T / No / 0.21 / 0.33
rs2423279 / HPFS1 / C / T / Yes / 0.27 / 0.99
rs2423279 / HRT / C / T / No / 0.25 / 0.23
rs2423279 / MEC / C / T / No / 0.27 / 0.34
rs2423279 / NHS1 / C / T / No / 0.25 / 0.70
rs2423279 / NHS2 / C / T / Yes / 0.27 / 0.94
rs2423279 / OFCCR / C / T / Yes / 0.21 / 0.98
rs2423279 / PHS12 / C / T / Yes / 0.27 / 0.98
rs2423279 / PLCO2 / C / T / No / 0.23 / 0.07
rs2423279 / VITAL / C / T / No / 0.25 / 1.00
rs2423279 / WHI1 / C / T / Yes / 0.25 / 1.00
rs2423279 / WHI2 / C / T / No / 0.27 / 0.30
rs4925386 / CCFR / C / T / No / 0.70 / 0.08
rs4925386 / Colo23 / C / T / No / 0.67 / 0.42
rs4925386 / DACHS1 / C / T / No / 0.68 / 0.87
rs4925386 / DACHS2 / C / T / No / 0.68 / 0.47
rs4925386 / DALS1 / C / T / No / 0.68 / 0.02
rs4925386 / DALS2 / C / T / No / 0.70 / 0.22
rs4925386 / HPFS1 / C / T / No / 0.68 / 0.55
rs4925386 / HRT / C / T / No / 0.66 / 0.55
rs4925386 / MEC / C / T / No / 0.69 / 0.38
rs4925386 / NHS1 / C / T / No / 0.68 / 0.36
rs4925386 / NHS2 / C / T / No / 0.71 / 0.28
rs4925386 / OFCCR / C / T / Yes / 0.72 / 0.97
rs4925386 / PHS12 / C / T / No / 0.70 / 0.18
rs4925386 / PLCO2 / C / T / No / 0.68 / 0.50
rs4925386 / VITAL / C / T / No / 0.72 / 0.30
rs4925386 / WHI1 / C / T / No / 0.70 / 0.81
rs4925386 / WHI2 / C / T / No / 0.70 / 0.41

ABBREVIATIONS: HWE (Hardy-Weinberg Equilibrium); RAF (risk allele frequency)

a Risk/base allele designation based on the literature