Supplemental Table 2: characteristics of patients completing follow up (n=20).
Baseline / 1 mo / 3 mo / 6 mo / 12 mo / P*Age (years) / 57±10 / - / - / - / - / -
Male gender (%) / 8 (40) / - / - / - / - / -
Fasting glucose level (mg/dl) / 148.3±45.7 / 133.8±31.1 / 129.4±31.9 / 142.2±50 / 152.2±72 / 0.537
HbA1c (%) / 7.8±1.3 / 7.2±0.9 / 7.1±1.1 / 7.5±1.3 / 7.3±1.5 / 0.456
Triglycerides (mg/dl) / 172.6±125 / 163.7±76.5 / 130.4±52.7 / 137±65.7 / 135.8±63 / 0.362
Total cholesterol (mg/dl) / 187.4±33.6 / 175±44.8 / 174.5±40.3 / 178±42.5 / 170.5±36 / 0.731
HDL cholesterol (mg/dl) / 47.5±14 / 46.2±13.5 / 47.5±12.5 / 49.5±12 / 47±10.8 / 0.943
LDL cholesterol (mg/dl) / 105.6±31 / 96.2±39 / 102±36 / 102±37 / 96.5±32.3 / 0.901
Lipase (u/l) / 42.3±17.2 / 89±65.5 / 76±57.8 / 60.3±22 / 61.5±29 / 0.015
Amylase (U/l) / 70±48.2 / 79±31 / 77.5±38.6 / 76.2±26 / 71±29 / 0.916
Serum Creatinine (mg/dl) / 0.9±0.3 / 0.89±0.25 / 0.88±0.4 / 0.87±0.5 / 0.89±0.31 / 0.947
BMI (kg/mt2) / 38.3±8.2 / 36.7±8.3 / 37.4±8.7 / 37.0±8.9 / 36.8±8.4 / 0.976
Waist (cm) / 122±13 / 118±14.5 / 117.5±15 / 116±15 / 114.5±15 / 0.587
FAT (Kg) / 38±10.7 / 38±11.7 / 38.2±14 / 38.3±13 / 37±11.3 / 0.989
FFM (Kg) / 53.4±9.2 / 61.3±15 / 63.3±17 / 60±17 / 60±15.5 / 0.631
Fasting Insulin Level (µUI/mL) / 18.6±9.5 / 22.3±18 / 19.2±9.5 / 17±7.5 / 20.5±15.3 / 0.756
C-peptide / 3.8±1.4 / 4.2±1.5 / 4.1±1.2 / 3.9±1.2 / 4.1±1.3 / 0.903
HOMA-IR / 6.9±4.3 / 7.4±6.6 / 6.1±3.3 / 5.8±2.7 / 7.3±5.5 / 0.751
TSH (uIU/ml) / 2.1±1.0 / 1.8±1.1 / 2.1±1.5 / 2.1±1.0 / 2.0±1.3 / 0.973
FT3 / 3.3±0.6 / 3.1±0.5 / 3.1±0.4 / 3.0±0.4 / 4.9±7.2 / 0.394
FT4 / 13±2.6 / 13.4±2.7 / 12.7±2.2 / 12.4±2.2 / 12.0±1.5 / 0.465
PTH (pg/ml) / 41±10.7 / 44.4±14.4 / 40±11 / 41±17.0 / 41.6±19 / 0.921
Serum Calcium (mg/dl) / 9.2±0.4 / 9.3±0.3 / 9.3±0.2 / 9.3±0.3 / 9.3±0.3 / 0.868
Legend: Values are expressed as mean ± SD. HbA1c = hemoglobin A1c; BMI = body mass index;
FAT = Fat mass; FFM = fat free mass; SD = standard deviation; normal range for lipase = 13-60 U/l; normal range for amylase = 28-100 U/l; * Paired One-Way ANOVA test.