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Shimona Geresh October 2002
CURRICULUM VITAE AND LIST OF PUBLICATIONS
Personal details
Name Shimona Geresh
Place of Birth: Iassi, Romania
Date of Immigration: August, 1961
Military service: Special academic reserve 1966-1974
Work address: The Institute for Applied Biosciences
Department of Biotechnology Engineering,
Ben-Gurion University of the Negev,
POBox 653, Beer-Sheva, Israel, 84105
Telephone at work: 972-8-6461903/945
Fax: 972-8-6479074
e-mail:
Home address: 27 Tapuz St., Omer, Israel 84965
Telephone at home: 972-8-6460644 or 972-8-909086/7
Education
B.Sc. 1966-1970
Technion, Israel Institute of Technology
Faculty of Chemistry, Haifa, Israel
Full year senior thesis - 1969-1970
Advisor: Professor Asher Mandelbaum
Thesis subject: Fragmentation of Organic Molecules where Double Charged Ions Represent the Most Abundant Peaks.
M.Sc. 1971-1973
Technion, Israel Institute of Technology
Graduate School, Haifa, Israel &
Ben-Gurion University of The Negev, Beer-Sheva, Israel
M.Sc. in Organic Chemistry and Photochemistry
Thesis Advisors: Professor Arnon Shani at BGU, Beer-Sheva
& Professor Mordechai Rubin at Technion, I.I.T., Haifa.
Thesis subject: Effects of Substituents on the Intramolecular
Photocycloaddition of Phenols to Olefins.
Ph.D. 1974-1978
Weizmann Institute of Science
Feinberg Graduate School, Rehovot, Israel
& Ben-Gurion University of The Negev, Beer-Sheva, Israel
Ph.D. in Organometallic Chemistry
Thesis Advisors: Dr. Robert Glaser at BGU &
Prof. Y. Menassen at the Weizmann Institute of Science
Thesis subject: Structural Requirements in Chiral Diphosphine-Rhodium Complexes.
First project: Insolubilization of Chiral Diphosphine-
Rhodium [I] Catalysts for Asymmetric Hydrogenation.
Main project: Determination of the Enantioface Differentiation Mechanism as Expressed in the Asymmetric Hydrogenation of N-acyldehydroamino Acids and Esters Catalyzed by Rhodium [I] Complexes of Chiral Diphosphines
PostDoc 1978-1979
Department of Chemistry,
Ben-Gurion University of The Negev, Beer-Sheva, Israel
Postdoctoral Research Associate
Advisor: Dr. Robert Glaser
Research topics: _
Asymmetric Hydrogenation of N-Acyldehydroamino Acids and Esters Catalyzed by Phospholyl-DIOP Rhodium [I] Complex.
PostDoc 1979-1981
Department of Chemistry,
Massachusetts Institute of Technology
Cambridge, Massachusetts 02139, U.S.A.
Area: Applied Enzymology
Advisor: Professor George M. Whitesides
Research topics:
1) Large Scale Preparation of S-Adenosyl- L-Methionine
2) Synthesis of Ribose-5-Phosphate
Employment History
1997
Associate Professor,
Institutes for Applied Research, Ben-Gurion University of the Negev, Beer-Sheva, Israel
1992-1993
Sabbatical at DuPont Co., Experimental Station, CR&D, P.O.Box 19880, Wilmington, Delaware 19880-0328, US
1991
Research Grade A,
Institutes for Applied Research, Ben-Gurion University of the Negev, Beer-Sheva, Israel
1988-1990
Lecturer - Organic Chemistry, Soroka Medical School,
Beer-Sheva, Israel
1986-1990
Member, Library Committee, Institutes for Applied Research, Ben-Gurion University of the Negev, Beer-Sheva, Israel
1982-present
Senior research chemist,
The Institutes for Applied Research,
Ben-Gurion University of the Negev, Beer-Sheva, Israel
1979,1981
Lecturer in General Chemistry, Department of Chemistry, Faculty of Natural Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel
1978-1979
Chemistry Teacher in the Pre-academic Studies Program
Ben-Gurion University of the Negev, Beer-Sheva, Israel
1977-1978
Part-time Instructor in Secondary School Sciences Program.
Israel Ministry of Education, Beer-Sheva, Israel
1971-1976
Part-time Instructor in Pre-academic Studies Program
Ben-Gurion University of the Negev
Professional Activities
(a) Positions in academic administration
2000
Assoc. Professor
Department of Biotechnology Engineering, Faculty of Engineering Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel
2000
Deputy, Sexual Harassment Committee
Ben-Gurion University of the Negev, Beer-Sheva, Israel
2000
Chair, Organizing Committee,
International Conference: 2000: The Era of Biotechnology,
Beer-Sheva, Israel
1998
Member, Organizing Committee, The Institute for Applied Biosciences, Ben-Gurion University ofthe Negev, Beer-Sheva, Israel.
Bi-National (Israel-Italy) Symposium on Polysaccharides: An interdisciplinary approach
1998
Head, Center of Polysaccharides,
The Institute for Applied Biosciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel
1998
Head, Graduate Studies Committee,
Biotechnology and Environmental Engineering Units, Faculty of Engineering Sciences, Ben-Gurion University of the Negev
1997
Member, Evaluation Committee: Research Grades and "Kamea" Fellowships, Ben-Gurion University of the Negev, Beer-Sheva, Israel
1997
Adjunct Associate Professor, Department of Chemistry, Faculty of Natural Sciences, Ben-Gurion University of the Negev
1992
Adjunct Senior Lecturer, Department of Chemistry, Faculty of Natural Sciences, Ben-Gurion University of the Negev
(b) Professional functions outside university
1998-2000
Member, Executive Committee, Israel Chemical Society
(f) Memberships in professional/scientific societies
1982-2001 Israel Chemical Society
1997-2000 Israel Society of Controlled Release of Biomaterials
Educational activities
(a) Courses taught
2002
Environmental Chemistry,
Graduate Students, Department of Biotechnology Engineering and Environmental Engineering, Faculty of Engineering Sciences, Ben-Gurion University of the Negev
2001
Organic Chemistry - Life Science students, Department of Chemistry, Faculty of Natural Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel
2000-2002
Organic Chemistry, Department of Biotechnology Engineering, Faculty of Engineering Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel
1998-2002
Biocatalysis in Organic Chemistry,
Graduate Students (Dept. Chemistry, Life Science, Biotechnology Engineering), Department of Biotechnology Engineering, Faculty of Engineering Sciences, Ben-Gurion University of the Negev
1998-2000
General Chemistry for Graduate Students, Environmental Unit, Faculty of Engineering Sciences, Ben-Gurion University of the Negev
1994-2000
Organic Chemistry for Biological and Chemical Engineering Students, Department of Chemistry, Faculty of Natural Sciences, Ben-Gurion University of the Negev
1993-2000
General Chemistry for Students in the Faculty of Engineering Sciences, Department of Chemistry, Faculty of Natural Sciences, Ben-Gurion University of the Negev
1989-1992
Senior Lecturer - General Chemistry, Department of Chemistry, Faculty of Natural Sciences, Ben-Gurion University of the Negev
1986-1987
Coordinator in Organic Chemistry Laboratory, Department of Chemistry, Faculty of Natural Sciences, Ben-Gurion University of the Negev
1986
Graduate Students Course - Novel Methods in Organic
Chemistry, Department of Chemistry, Faculty of Natural Sciences, Ben-Gurion University of the Negev
1984
Lecturer - Inorganic Chemistry, Department of Chemistry, Faculty of Natural Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel
1983
Lecturer at the Pedagogical Institute to Elementary School Teachers, Beer-Sheva, Israel
1982-1983
Lecturer - Organic Chemistry, Department of Chemistry, Faculty of Natural Sciences, Ben-Gurion University of the Negev
1983
Lecturer - General Chemistry, Soroka Medical School, Ben- Gurion University of the Negev
1984-1990
Graduate Students Course, Preparation and Lecturing -
Enzymes - Synthetic Tools in Organic Chemistry.
Department of Chemistry, Faculty of Natural Sciences, Ben- Gurion University of the Negev
(b) Research students
Liza Gurvitz, M. Sc. student, Faculty of Engineering Sciences, Department of Biotechnology, "Ionic Liquids", 2001-
Lindi Kahanovitz, M. Sc. student with Dr. Robert Marks and Prof. Judith Rishpon (TAU), Faculty of Engineering Sciences, The Unit of Environmental Engineering, Ben-Gurion University of the Negev, "Electrochemical biosensors", 2001-
Zhan Wang, Postdoctoral fellow, Institute for Applied Biosciences, Institutes for Applied Research, 2000- 2002
Silvina Guernik, M. Sc. student with Prof. R. Glaser, Department of Chemistry, Ben-Gurion University of the Negev, "Asymmetric hydrogenations in ionic liquids", 2001-
Isac Ergaz, Ph.D student with Prof. R. Glaser, Department of Chemistry, Ben-Gurion University of the Negev, “Nefopam analogs with eight and nine member rings" 2000-
Dvora Bitty, M. Sc. student with Dr. Alex Sivan, Faculty of Engineering Sciences, The Unit of Environmental Engineering, Ben-Gurion University of the Negev, "Biodegradation of polyethylene by soil bacteria" 2000-
Asher Vishkerman, M.Sc. student with Prof. S. Arad (Malis), Faculty of Engineering Sciences, The Unit of Environmental Engineering, Ben-Gurion University of the Negev, "Heavy metal sorption by red microalgae", 1999-
Sandra Visnovsky, M.Sc. student with Dr. Ethan Bar, Faculty of Engineering Sciences, The Unit of Environmental Engineering, Ben-Gurion University of the Negev, "Development of Microalgal Polysaccharide-based resin for the removal of toxic ions from waste waters", 1998-2001
Hila Rudoy, M. Sc. student with Dr. Robert Marks and Prof. Judith Rishpon (TAU), Faculty of Engineering Sciences, The Unit of Environmental Engineering, Ben-Gurion University of the Negev, "Amperometric biosensors for environmental pollutants" 1999-2001
Adi Wolfson, Ph.D student with Prof. M. Herskowitz, Department of Chemical Engineering, Ben-Gurion University of the Negev, "Enantioselective Hydrogenation of Carbonyl Compounds by Heterogeneous Catalysis", 1997-2001
V.T. Jacob, Postdoctoral fellow, Institutes for Applied Research and Blechner Center in Catalysis, Ben-Gurion University of the Negev, 1996-1997
Julia Peisahov, M.Sc. student, Department of Chemistry, Ben-Gurion University of the Negev, “Preparation and characterization of graft-polymers for drug delivery systems”¨†1995-1997
Ganit Levi-Roso, Ph.D student with Prof. R. Glaser, Department of Chemistry, Ben-Gurion University of the Negev, “Determination of the Bioactive Conformation of Serotonin Reuptake site inhibitors, and Synthesis of Benzoxazocines for PET (Positron Emission Tomography) of Serotonin Reuptake Process", 1997- 2001
Moti Prengler, M.Sc. student with Prof. S. Arad (Malis), Faculty of Engineering Sciences, The Biotechnology Unit, Faculty of Engineering Sciences, Ben-Gurion University of the Negev, "Isolation and Characterization of mutants in the carotenoids biosynthesis pathway in the green microalga Chlorella emersonii¨ 1994-1996.
Beiley Turdjman, M.Sc. student with Prof. A. Shani, Department of Chemistry, Ben-Gurion University of the Negev, "Enzymatic oxidation of long-chain primary alcohols with regeneration of cofactors", 1987-1989.
Anat Shemesh M.Sc. student with Prof. A. Shani, Department of Chemistry, Ben-Gurion University of the Negev, "Preparation of chiral synthons for the synthesis of optically active pheromones", 1989-1991.
Yair Lavie, M.Sc. student with Prof. A. Shani, Department of Chemistry, Ben-Gurion University of the Negev, "Preparation of chiral synthons for the synthesis of optically active pheromones using Baker's yeast as a reduction agent", 1989-1991.
Ely Golan, M.Sc. student with Prof. A. Shani, Department of Chemistry, Ben-Gurion University of the Negev, "Enzymatic synthesis of optically active cyanohydrins." 1990-1993.
Ariel Peleg, M.Sc. student with Prof. R. Glaser, Department of Chemistry, Ben-Gurion University of the Negev, "Analogs of nefopam." 1988-1990.
Jeanine Blumenfeld, Ph.D. student with Prof. R. Glaser, Department of Chemistry, Ben-Gurion University of the Negev, "Structure-activity relationships in the benzoxazocine family of drugs." 1987-1991.
Yakir Gyron, M.Sc. student with Prof. R. Glaser, Department of Chemistry, Ben-Gurion University of the Negev, "Enzymatic hydrolysis of substituted benzyl cyanides." 1988-1990.
Elisabeth Elbaz, M.Sc. with Prof. R. Glaser, Department of Chemistry, Ben-Gurion University of the Negev, "Enzymatic resolution of cis/trans cyclohexane 1,4-dimethanols and synthesis of polyesters with them." 1990-1993.
1983-1988: Projects instructor at the Practical Engineering College, Beer-Sheva, Israel: Routes to the synthesis of Californian Red Scale pheromone, T. Amar.
Polymer-buffers, A. Amar.
Enzymatic resolution of racemic citronellyl butyrates. Z. Reichman
Asymmetric reductions of beta-ketoesters with yeast, J. Arzuan.
NAD´/NADH regeneration. P. Aknin. Enzymatic resolution of 2-halo-acids, G. Azulai. Enzymes immobilization. F. Levi Asymmetric reductions of terpenes with yeast, A. Vangrowsky. Lipids extraction from red algae, S. Reichman. Odour materials in the Israeli Tuber, C. Turdjman.
Awards, Citations, Honors, Fellowships
a) Honors, Citation Awards
1969, Technion-Israel Institute of Technology, Haifa, Philip Ash Memorial Prize
1970, Technion-Israel Institute of Technology, Haifa,
Delek (Israel Petroleum Company) Prize
1973, Ben-Gurion University of the Negev, Delek
Graduate Award
1988, Machteshim Ltd., Masha and Zvi Sheriv Excellency Prize
1996, Dead Sea Bromine Group Ltd., Citation Award
(b) Fellowships
1979, Rothschild Postdoctoral Fellowship, $8,000
1979-1981, Chaim Weizmann Postdoctoral Fellowship, Israel Academy of Sciences, $21,000 per year
Scientific Publications
(c) Chapters in collective volumes
1. Geresh, S., 1990. Enzymatic synthesis of alkids, Rieke, P.C., Calvert P.D., Alper, M. eds., "Materials Synthesis Utilizing Biological Processes" MRS Symposium Proc. Material Research Soc. Publ., Pittsburg, Penn., 174, 209-216.
2. Geresh, S. and Abrahami, S., 1991. Comparison of "all trans" enzymatically prepared unsaturated polyesters with chemically synthesized and industrial polyesters, ANTEC Proceedings, 743-746.
3. Geresh, S., Peisahov, J., Voorspoels, J., Remon, J.-P., Kost, J., 1998. Preparation and characterization†of buccal bioadhesives from starches grafted with acrylic monomers, "New Biomedical Materials - Applied and Basic Studies", Dennis Chapman and Parvez Haris Eds., 16, 192-196.
4. A. Yaron, M. Rise, S. Geresh and S. (Malis) Arad, 1998. Microalgal pigments for cosmetics and toiletries. Proceedings of the Third International Symposium on Natural Colorants for Food Nutraceuticals, Beverages, Confectionery and Cosmetics. The Herald Organization, Hamden CT 199-204.
(d) Refereed articles in scientific journals
1. Houry, S. Geresh, S. and Shani, A. Substituent effects in the intramolecular photocyclization of o-allylphenols to cyclic ethers. Isr. J. Chem. 11 (6): 1973.
2. Geresh, S., Levi, O., Markovits, Y. and Shani, A. On the mechanism of intramolecular photocycloaddition of substituted o-allylphenols to cyclic ethers. Tetrahedron 31: 2803 (1975).
3. Glaser, R., Geresh, S. and Blumenfeld, J. Structural requirements in chiral diphosphine- rhodium complexes. III. Small scale method for fresh preparation of cationic DIOP-rhodium complexes and comparison with neutral DIOP-rhodium complexes. J. Organometal. Chem. 112:355 (1976).
4. Glaser, R., Geresh, S., Blumenfeld, J., Vainas, B. and Twaik, A. Structural requirements in chiral diphosphine-rhodium complexes. V. Asymmetric homogeneous hydrogenation of Z-alpha-acetamidocinnamate esters of chiral alcohols with DIOP-rhodium [1] complexes. Invited contribution to special issue on Chiral Structure. Isr. J. Chem. 15: 17 (1976-77).
5. Glaser, R. and Geresh, S., Structural Requirements in chiral diphosphine rhodium Complexes. VII. Use of Z-methyl-alpha-acylaminocinnamates as structural probes for DIOP-rhodium [1] complexes. Tetrahedron Letters 2527 (1977).
6. Glaser, R., Geresh, S., Blumenfeld, J. and Tawik, M. Structural requirements in chiral diphosphine-rhodium complexes.VIII. Asymmetric hydrogenation of N-acetyldehydro-amino acids with rhodium [1] complexes containing carboxylic analogues of DIOP. Tetrahedron Letters 4635 (1977).
7. Glaser, R., Geresh, S., Schollkopf, U. and Meyer, R. Structural requirements in chiral diphosphine-rhodium complexes. IX. 1H NMR determination of E,Z-configuration and cis, trans-amide conformations in prochiral substrates used in asymmetric hydrogenation reactions: Methyl and ethyl-N-formamido-beta-substituted acrylates. J. Chem. Soc. Perkin I: 1746 (1979).
60. Glaser, R., Geresh, S., Blumenfeld, J. and Twaik, A., Structural requirements in chiral diphosphine-rhodium complexes. XI. Asymmetric homogeneous hydrogenation of Z-alpha-acylamino- cinnamic acids and esters with (1S,2S)-trans-1,2 bis (diphenylphos- phinomethyl)cyclohexane rhodium [1] complexes. Tetrahedron 34: 2405 (1978).
9. Glaser, R., Geresh, S., Twaik, A. and Benoiton, N.L. Structural requirements in chiral diphosphine-rhodium complexes. XII. Asymmetric homogeneous hydrogenation of Z-alpha-N-methyl- acetamidocinnamic acid and methyl ester catalyzed by Rhodium [1] complexes of DIOP and its carbocyclic analogues. Tetrahedron 34: 3617 (1978).