Inventory of Administrative and Clinical Datasets with Possible Applications to Multiple Sclerosis Research

Appendix-e4. Preparation of dataset inventory

Table of Contents

Acknowledgements & Disclaimer 16

Findings 17

Table 1. Comparison of administrative datasets worldwide 17

Table 2. List of data sources with countries of origin, comorbidities evaluated and first author of publication. 23

Administrative Data Sources 30

North America 30

Canada 30

National Databases 30

Discharge Abstract Database (DAD) 30

The Hospital Morbidity Database (HMDB) 31

National Ambulatory Care Reporting System (NACRS) 32

Provincial Databases 33

Alberta 33

Alberta Health Care Insurance Plan (AHCIP) Registry 33

Inpatient Discharge Abstract Dataset (DAD) 34

Ambulatory Care Classification System Dataset 34

Practitioner Payments Dataset 35

Population Registry 35

Pharmacy Data- Alberta Blue Cross 35

Multiple Sclerosis Clinic Database, University of Calgary 36

British Columbia (BC) 36

Population Data BC 36

Medical Services Plan (MSP) Payment Information Dataset 37

Pharmacare 38

PharmaNet 38

https://www.popdata.bc.ca/data/external/PharmaNet?nopaging=1 39

Discharge Abstract Database (DAD) 39

Mental Health 39

BC Cancer Agency 40

Demographics Dataset: Consolidation File 40

British Columbia Multiple Sclerosis Database (BCMS) 40

Manitoba 41

Population Health Research Data Repository 41

Hospital Discharge Abstracts Data (DAD): 42

Medical Services Data (Physicians Claims) 42

Drug Program Information Network Data 43

Mental Health Management Information System (MHMIS) 43

Urgent Care 44

Emergency Care Database 44

Multiple Sclerosis Clinic Database and Registry, Health Sciences Centre, Winnipeg 45

Nova Scotia 45

Research Data Repository 45

Physician Billings Database 46

Hospital Discharge Abstract Database 46

Mental Health Outpatient Information System (MHOIS) 46

PharmaCare Prescriptions 47

Insured Patient Registry (MASTER) 47

Dalhousie MS Research Unit (DMSRU) Database 48

Newfoundland & Labrador 48

Newfoundland & Labrador Centre for Health Information 48

Clinical Database Management System (CDMS) (CIHI Discharge Abstract Database) 49

MCP Fee-for-Service Physician Claims Database 49

Newfoundland & Labrador Prescription Drug Program Dataset 49

Newfoundland & Labrador Chronic Disease Surveillance System 50

Cancer and Chronic Disease Research Database 50

Ontario 51

The Institute for Clinical Evaluative Sciences (ICES) 51

Ontario Health Insurance Plan (OHIP) Database 52

Discharge Abstracts Database (DAD) and Same Day Surgery Database (SDS) 52

Ontario Drug Benefits Claims 52

National Ambulatory Care Reporting System 53

Ontario Mental Health Reporting System 53

Cardiac Care Network 54

CT/MRI Abstraction Data 54

Ontario Cancer Registry 54

Ontario Diabetes Database 55

Quebec 55

EPSEBE (Environnement pour la Promotion de la Santé et du Bien-être) 55

Re´gie d’Assurance Maladie du Québec (RAMQ) (Physician Billing Database) 56

Fichier d'admissibilité au régime général d'assurance médicaments (Prescription Drug Insurance) 57

Maintenance et Exploitation des Donne´es Pour l’Etude de la Clientèle Hospitalière (Hospital Discharge Database) 57

Saskatchewan 58

Saskatchewan’s Health Services Databases 58

Prescription Drug Data 58

Hospital Services Data 59

Medical Services Data 59

Cancer Registry 60

United States 61

Medicare/Medicaid 61

Medicare 61

Medicaid 62

Chronic Condition Data Warehouse (CCW) 64

Master Beneficiary Summary File 65

Institutional and Non-institutional fee-for-service files 65

Inpatient (IP) Base Claim Files 65

Outpatient (OP) Base Claim Files 65

Part D Prescription Drug Event data 65

Medicaid Analytical Extracts (MAX) Inpatient Files 65

Medicaid Analytical Extracts (MAX) Drug Files 65

Medicaid Analytical Extracts (MAX) Personal Summary Files 65

Medicare-Medicaid Linked Enrollee Analytic Data Source 65

SEER-Medicare Linked Data 65

Veterans Administration Databases (VHA) 66

VHA Corporate Data Warehouse (CDW) 67

Inpatient 68

Outpatient 68

Mental Health Assessment 68

Patient (demographics) 68

Pharmacy 68

Staff (demographics, provider type) 68

Vital Signs 68

Decision Support System (DSS) National Data Extracts 68

DSS Discharge NDE 69

DSS Treating Specialty ND 69

Outpatient NDE 69

DSS National Pharmacy Extract: 69

Medical SAS datasets 69

Outpatient Medical SAS datasets 69

Inpatient Medical SAS datasets 70

Inpatient Encounter Medical SAS datasets 70

Kaiser Permanente 71

Kaiser Permanente Northern California (KPNC) 72

Chronic Disease Registries 73

SEER-quality KP Northern California Cancer Registry 73

KP Diabetes Registry 73

KP HIV/AIDS Registry 73

KP Asthma 73

KP Coronary Artery Disease 73

KP Congestive Heart Failure 73

KP Diabetes 73

KP Maternal Prenatal Drug/Alcohol Use 73

Inpatient Hospitalizations 73

Ambulatory Visits 74

Outside Referrals and Claims 74

Health plan Membership 74

Pharmacy 74

Patient Demographics 75

Kaiser Permanente Centre for Health Research 75

Kaiser Permanente Georgia Region (KPG) 76

Kaiser Permanente Hawaii 76

Kaiser Permanente Northwest 77

Kaiser Permanente Southern California 77

Indian Health Service (IHS) National Data Repository 78

National Hospital Discharge Survey (NHDS) 80

IMS LifeLink™ PharMetrics plus Database 81

HMO Research Network Virtual Data Warehouse (HMORN VDW) 82

Kaiser Permanente Colorado 83

Kaiser Permanente Southern California 83

Kaiser Permanente Northern California 83

Kaiser Permanente Mid-Atlantic 83

The Centre of Health Research 83

Geisinger Health System 83

Essentia Health 83

Group Health 83

Harvard Pilgrim Health Care 83

Health Partners 83

Henry Ford Health System 83

Marshfield Clinic Security Health Plan of Wisconsin 83

Fallon Community Health Plan Reliant Medical Group 83

Palo Alto Medical Foundation for Healthcare, Research and Education (PAMF) 83

Scott and White Healthcare 83

Fallon Clinic/Reliant Medical Group 84

Lovelace Clinic Foundation (LCF) Quality Research Data Warehouse 85

Demographics 85

Membership Information 85

Geographic Information 85

Inpatient 85

Outpatient 85

Pharmacy Systems 85

Geisinger Health System 86

Geisinger’s Clinical Decision Intelligence System (CDIS) 87

HealthCare Partners Medical Group database 88

United HealthCare Database 89

Medstat’s MarketScan Claims and Encounters 90

New York Department of Health Statewide Planning and Research Cooperate System (SPARCS) 91

Explorys 93

Cerner Health Facts® Database 93

New York State Multiple Sclerosis Consortium database (NYMSC database) 95

The Pacific Northwest Multiple Sclerosis Registry & Network 95

Mexico 95

National Mortality Statistics 95

Encuesta Nacional de la Dinámica Demográfica (ENADID) (National Demographics Survey) 95

South America 96

Argentina 96

Cause-of-Death Records 96

Registro Institucional de Tumores de Argentina (RITA) (Cancer Registry) 97

Brazil 98

DATASUS 98

Primary Care Information System (SIAB) 98

Sistema de Informações Hospitalares (SIH-SUS) (Hospital Systems Data) 99

Sistema de Cadastramento e Acompanhamento de Hipertensos e Diabéticos 99

Mortality Information System (MIS) 100

Europe 101

Austria 101

DIAG-Extranet 101

GAP-DRG (General Approach for Patient oriented Outpatient-based DRG) 102

Austrian National Cancer Registry 103

Cause of Death Statistics 104

Belgium 104

Résumé Clinique Minimum et Résumé Financier Minimum 105

PharmaNet Database 105

Belgium Cancer Registry 106

IMS LifeLink™ Belgian Hospital Disease Database 106

Bulgaria 107

National drug consumption database of the Bulgarian Drug Agency 107

Czech Republic 108

National Register of Hospitalized Patients 108

Czech National Cancer Registry (CNCR) 109

National Register of Cardiac Surgery (NKCHR) 110

National Register of Cardiovascular Interventions (NRKI) 111

National drug consumption database of the State Institute for Drug Control (SUKL) 112

Denmark 113

The Danish National Database of Reimbursed Prescriptions (DNDRP) 113

Danish National Registry of Patients 114

Danish Cancer Registry 115

Psychiatric Central Research Register 116

Danish Twin Registry 117

Danish Education Registers 117

Student Register (SR) 118

Academic Achievement Register (AAR) 118

Population’s Education Register (PER) 118

Adult Education and Continuing Training Register 118

Danish Heart Register 118

Danish Injury Register 119

Danish registers on personal income and transfer payments 120

Danish Multiple Sclerosis Register 120

Estonia 121

The Estonian Health Insurance Fund Administrative Database 121

Health Statistics and Health Research Database 122

Estonian Cancer Registry 122

Estonian Causes of Death Registry 123

The Estonia Health Interview Survey 123

Health Behavior among Estonian Adult Population 124

Finland 125

Finnish National Hospital Discharge Register 126

Kelasto Database (Finnish Prescription Registry) 126

Causes of Death Registry 127

Finnish Cancer Registry 128

Health 2000/2011 Interview Surveys 2000 and 2011 128

France 129

Programme de Médicalisation des Systèmes d’Information (PMSI) 129

Système National d’Information Inter-Régime de l’Assurance Maladie (SNIIR-AM) (National Claims) 130

FRANCIM (French National Cancer Register) 131

ANMS Database 132

Enquête Décennale de Santé 132

Enquête Santé et Protection Sociale (ESPS) 133

European Database for Multiple Sclerosis (EDMUS) 134

Germany 134

German Statutory Health Insurance Claims (SHIs) 134

Core Data 135

Inpatient Data 135

Outpatient Data 135

Prescription Data 135

IMS Disease Analyzer Database 135

Cancer Registry Data 136

WIdO Database 137

Robert Koch Institute (RKI) 138

Health Surveys available through RKI 138

GEDA(German Health Update survey) 138

German Health Interview and Examination Survey for Adults (DEGS) 138

Multiple Sclerosis Registry in Germany 139

Hungary 139

National Health Insurance Fund database (NHIFA) 139

National Drug Consumption Database of the Directorate General of National Institute of Pharmacy 141

Iceland 142

Icelandic National Register of Persons 142

Iceland Cancer Registry 142

Italy 143

OsMed Database 144

The Health Search Database (HSD) 144

Veneto Region Health Services 145

Hospital Discharge Records 146

Drug Dispensing Records 146

Disease-Specific Exemptions from Copayment to Health Care 146

Inhabitant Registry (IR) 146

Servizio Sanitario Regionale Emilia-Romagna 147

Hospital Discharge Records 147

Drug Dispensing Records 147

Inhabitant Registry (IR) 147

Regional Health Agency of Tuscany 148

Hospital Discharge Records 148

Drug Dispensing Records 148

Disease-Specific Exemptions from Copayment to Health Care 148

Inhabitant Registry (IR) 149

Agenzia Regionale Sanitaria Marche 149

Hospital Discharge Records 149

Drug Dispensing Records 149

Disease-Specific Exemptions from Copayment to Health Care 150

Inhabitant Registry (IR) 150

Sicily (Southern Italy) 150

Contact or 150

Hospital Discharge Records 151

Drug Dispensing Records 151

Disease-Specific Exemptions from Copayment to Health Care 151

Inhabitant Registry (IR) 151

Italian Multiple Sclerosis Database Network (MSDN) 152

Latvia 152

National drug consumption database of the State Agency of Medicines of Latvia 152

Statistics Latvia 152

Netherlands 153

Dutch Hospital Data (DHD) 154

Rural Hospital Care Key Register 154

National Medical Registration 154

National Ambulatory Registration 154

Diagnosis-Treatment-Combination Information System 154

Hospital Surveys 154

GIP Database 155

NIVEL Primary Care Database 156

Dutch Cancer Registry 157

PHARMO 158

General Practitioner Database (GPD) 158

Outpatient Pharmacy Database 159

In-patient Pharmacy Database 159

Norway 159

Norwegian Patient Register 159

Norwegian Cancer Registry (NCR) 160

Norwegian Prescription Database (NorPD) 161

Norwegian Cardiovascular Disease Registry 162

Cause of Death Registry 162

The Norwegian Multiple Sclerosis National Competence Centre and National Multiple Sclerosis Registry 163

Poland 163

National Health Fund Database 163

Portugal 164

INFAR Med’s Database 164

Serbia 165

Institute of Public Health 165

Diabetes Registry 165

Cancer Registry 165

Acute Coronary Syndrome 166

National Health Survey 2006 166

Institute of Neurology, Belgrade School of Medicine 166

Spain 166

National Statistics Office Datasets 166

Hospital Morbidity Survey 167

Encuesta Nacional de Salud (National Health Survey) 167

National Vital Statistics 168

FAP (Database for Pharmacoepidemiological Research in Primary Care) 168

DGFPS Database 169

MONICA-Catalonia Study 170

Slovenia 170

Cancer Registry 170

Sweden 171

National Patient Register (NPR) (Hospital Discharge Register) 171

Swedish Cancer Registry (NPR) 173

Drug Prescription Register 174

The Swedish Cause of Death Register 174

IMS LifeLink™ Longitudinal Patient Database in Sweden 175

National Swedish MS Register 176

Switzerland 176

Swiss National Cohort (SNC) 176

Vital Statistics 177

Swiss Health Survey 178

NICER Database 179

Swiss MONICA (Monitoring of trends and determinants in CVD) 180

United Kingdom 181

Clinical Practice Research Data link (CPRD) (formerly General Practice Research Database - GPRD) 181

Diagnosis 181

Procedures 181

Drug data 181

Central Mortality Data 181

Census Data 181

Disease Registries: Cardiovascular Disease, Stroke, Cancer, Diabetes, Epilepsy, Pain, IBD, Dementia, Schizophrenia 181

Health and Social Care Information Centre (HSCIC) 183

Hospital Episode Statistics (HES) 184

Payment by Results data 184

Mental Health Minimum Data Set 184

Cancer Datasets 185

Coronary Heart Disease Data Set 186

HIC (Health Informatics Centre) 186

ISD SMR00 dataset 187

ISD SMR01 dataset 187

ISD SMR04 dataset 188

ISD SMR06 dataset 188

Prescription Data 188

Accident & Emergency (A&E) 188

Ambulatory Holter Monitoring Data 188

ECHO cardiogram set 188

Epidemiology of liver disease in Tayside 189

Heart-disease Evidence-based Audit & Research Tayside Scotland (HEARTS) 189

Renal Register 189

Rheumatoid Arthritis dataset 189

Scottish Care Information - Diabetes Collaboration 189

Stroke Dataset 189

Tayside Allergy & Respiratory Disease Information System (TARDIS) 190

Thyroid Epidemiology, Audit & Research Study (TEARS) 190

GRO Death Certification 190

ISD Scotland 190

Accident and Emergency (A&E2) 191

ACaDMe 191

Data Completeness 191

Outpatients (SMR00) 191

PRISMS 192

The Scottish MS Register 192

The Health Improvement Network (THIN) 192

GPMD (General Practice Morbidity DatabaseProject Wales) 193

Asia 194

China 194

National Central Cancer Registry (NCCR) 196

Chen W, Zheng R, Zhang S, Zhao P, Li G, Wu L, & He J. The incidences and mortalities of major cancers in China, 2009. Chinese Journal of Cancer 2013, 32 (3): 106-112. 196

India 196

Census Data 196

Annual Health Survey 197

Israel 198

Israel National Population Register 198

National hospital services data 199

Israel National Cancer Registry 199

Cause of Death Registry 200

The Maccabi Healthcare Services Clinical Database 201

MS Center Registry at the Sheba Medical Center Hospital 202

Islamic Republic of Iran 202

Iranian MS Society (IMSS) 202

National Death Registry 202

National Cancer Registration 203

Japan 204

Japan Medical Data Center (JMDC) National Claims Database 204

Osaka University Hospital 205

NBD National Claim Database 206

Medical Data Vision 207

JammNet 207

IMS NPA Data 208

Korea 209

Korea National Health insurance claims database 209

Taiwan 210

Taiwan National Health Insurance Research Database (NHIRD) 210

Turkey 211

Turkey Vital Registration 211

TÜRKİYE SAĞLIK ARAŞTIRMASI (Turkey Health Interview Survey) 212

CancerRegistry 212

Africa 213

South Africa 213

Civil Registration 213

Australia and New Zealand 214

Australia 214

Australian Institute of Heath and Welfare (AIHW) 214

National Hospital Morbidity Database (NHMD) 215