Supplement Table 1 Subgroup analysis between analyzed and not analyzed data regarding preoperative characteristics

Study participants
(n=300) / CVI Group
(n=150) / PSI Group
(n=150)
Analyzed
(n=222) / Not analyzed1
(n=78) / P-Value / Analyzed
(n=108) / Not analyzed1
(n=42) / P-Value / Analyzed
(n=114) / Not analyzed1
(n=36) / P-Value
Demographics
Age*(years) / 68.2 ± 8.9 / 71.6 ± 8.4 / 0.004 / 67.7 ± 9.6 / 72.4±8.9 / 0.008 / 68.7±8.2 / 70.7±7.7 / n.s.
Female/male†(n) / 136/86 / 47/31 / n.s. / 63/45 / 26/16 / n.s. / 73/41 / 21/15 / n.s.
Body mass index*(kg/m2) / 29.9±5.3 / 29.1±4.9 / n.s. / 29.8 ± 5.4 / 29.6±5.7 / n.s. / 29.9±5.2 / 28.4±3.9 / n.s.
Right/left knee†(n) / 117/105 / 40/38 / n.s. / 57/51 / 20/22 / n.s. / 60/54 / 20/16 / n.s.
Varus/valgus†(n) / 170/52 / 50/24 / n.s. / 81/27 / 23/15 / n.s. / 89/25 / 27/9 / n.s.
Preoperative clinical and radiological assessment
KSS knee*(0-100 points) / 43.6±21.1 / 38.5±23.5 / n.s. / 44.3±18.6 / 42.3±18.4 / n.s. / 42.8±23.3 / 34.1±27.9 / n.s.
KSS function*(0-100 points) / 50.1±24.8 / 46.5±28.6 / n.s. / 53.1±22.6 / 51.9±24.9 / n.s. / 47.4±26.5 / 40.3±31.7 / n.s.
Range ofmotion*(°) / 110.3±16.3 / 109.4±17.9 / n.s. / 109.6±16.2 / 109.4±16.0 / n.s. / 110.9±16.4 / 109.4±20.0 / n.s.
VAS pain*(0-10 points) / 7.2±1.8 / 7.5±1.6 / n.s. / 7.5±1.5 / 7.7±1.5 / n.s. / 7.0±2.0 / 7.1±1.6 / n.s.
HKA*(°) / 176.0±6.3 / 177.8±8.7 / n.s. / 176.4 ± 6.3 / 179.2±9.2 / 0.043 / 175.6 ± 6.4 / 176.3±7.9 / n.s.
HKA deviation* from neutral(°) / 6.3±4.0 / 7.4±5.0 / n.s. / 5.9±4.2 / 7.3±5.5 / n.s. / 6.8±3.7 / 7.4±4.4 / n.s.

*The values are given as the mean and the standard deviation, with the range in parentheses. †The values are given as numbers.

1 No or bad quality radiographs were available for four knees preoperatively.

Abbreviation: CVI, conventional instrumentation; PSI, patient-specific instrumentation; KSS, Knee Society Score; HKA, hip-knee-ankle angle; STD, standard; UC, ultra-congruent; VAS, visual analog scale for pain.