RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES,

KARNATAKA, BANGALORE.

ANNEXURE – II

APPLICATION FOR REGISTRATION OF SUBJECTS FOR DISSERTATION

1 / NAME OF THE
CANDIDATE
AND ADDRESS /

Dr. DEEPIKA .B.C

PRESENT ADDRESS:

PLOT.NO.111, SIDDHARTH,

TV CENTRE, BELGAUM 590001.

PERMANENT ADDRESS:

C/O DR.DEEPIKA. B.

PLOT NO.111, “SIDDHARTH”,

TV CENTRE, BELGAUM -590001.
2 / NAME OF THE
INSTITUTION. /

A.M. SHAIKH HOMOEOPATHIC

MEDICAL COLLEGE, HOSPITAL AND PG RESEARCH CENTRE, NEHRU NAGAR,BELGAUM- 10
3 / COURSE OF THE STUDY
& SUBJECT /

M.D. (HOM)

REPERTORY.
4 /

DATE OF ADMISSION

TO THE COURSE.

/ 21-6-2011
5 / TITLE OF THE TOPIC / UTILITY OF SYNTHESIS 9.1 REPERTORY IN THE MANAGEMENT OF “PSORIASIS”.
6. / BRIEF RESUME OF THE INTENDED WORK:

6.1) NEED FOR THE STUDY:

Psoriasis is a common skin disease affecting about 1 -2% of general population. Its onset is usually second to fourth decade of life. It is a chronic dry inflammatory disease of the skin characterized by various sized reddish, sharply defined patches, covered with abundant, silvery white adherent scales.
The conventional system of medicine treats this condition with application of ointments, poisonous washes etc,inspite of these application there is a chance of periodic remissions and exacerbations and the carcinogenic hazards caused by the ultraviolet therapies.
These kind of treatment only palliates the condition which drives the disease into the system and combines the drug effect with the natural disease. Homoeopathy helps us to treat such cases constitutionally and long with external application, internal homeopathic medicines are needed to drive the disease completely out of the body.
Homoeopathic science deals with treating patients with totality of symptoms and individualization which is a rational way in dealing with such kind of manifestation. The present study of repertorial approach in the management of psoriasis is an attempt to highlight the utility of synthesis repertory 9.1 in choosing the most similar remedy for psoriasis.synthesis 9.1 helps in selecting the remedy more accurately as there are large number of choices by including remedies from sub rubrics into their mother rubrics and by restructuring of sensations and location in the repertory.
HYPOTHESIS:
Null hypothesis- homoeopathic remedies are not effective in the treatment of psoriasis.

6.2) REVIEW OF LITERATURE.

•  Psoriasis is characterized by development of asymptomatic or mildly pruritic erythematous well defined scaly papules and plaques. Scales are dry, loose,abundent and silvery white which on scraping multiple bleeding points can be seen called auspitz sign. 1
•  It is non infectious disease of skin with predilection for extensor surfaces and scalp. Clinical course is variable. As a general rule it suggests that earlier the age of onset and more severe initial presentation, more severe the lifetime course of disease.
Davidson describes the following types of psoriasis:
-  Stable plaque psoriasis
-  Guttate psoriasis
-  Erythrodermic psoriasis
-  Pustular psoriasis
-  Psoriatic arthropathy. 2
•  It is common disease constituting 3-4% of all dermatological cases, but this is owing more tendency to reccur, than actual new cases. It shows systemic origin by occuring symmetrically and its probable connection with some internal derangement by beginning on surface where the circulation is less active, namely the extensor surfaces, of all cases there is some hereditary evidence. 3
·  The remedies found for psoriasis in the Dr.GHG JHAR 40 years practice are, - phophorous, lyco, sulph, rhus tox, nitric a, petro, sepia. 4
•  Remedies found in homoeopathic medical repertory by Dr. Robin Murphy are,
Chapter- skin, rubric- psoriasis skin,
Ars, Ars iod, Calc-s,,canth ,chin ,clem , Graph, kali c, Nat mur, Sepia, Staph, Thyr.5
•  Remedies found in synthesis 9.1 repertory by Dr. Schroyens are,
Chapter- skin. Rubric- eruptions (psoriasis),
Ant t , calc s, chrys , iris, kali ars, puls, Ars iod, alum, lyco, phyt, sep, carb veg, merc.6
•  It is considered to be inherited as an autosomal dominant character with irregular penetrance. It is found in more than one member of family in 10-30% cases. The exact cause is not known, however it is seen that time taken for transfer of epidermal cells from basal cell layer to outer surface of skin is drastically reduced from normal one month to three to five days. This results in formation of immature epidermal cells which shed as scales.7
•  The remedies found in the prescriber by Dr. J H Clarke are,
Ars, thyr, cup met, petro, thuj, merc, graph.8
•  It is a chronic autoimmune disease that appears on skin. It occurs when immune system sends out faulty signals that speed up the growth cycle of skin cells.9
•  Psoriasis affects the skin and joints. It causes red scaly patches on skin, which are called psoriatic plaque. This condition is neither infectious nor does it affect the general health.10

6.3) OBJECTIVES OF STUDY:

•  To study the clinical presentation of psoriasis.
•  Assessment of constitutional remedies in management of psoriasis.
• To compile a clinical repertory on psoriasis for easy reference in clinical practice.
7 / MATERIALS AND METHODS:

7.1 SOURCE OF DATA.

The subjects for the study will be taken from OPDs and IPDs, village camp, satellite OPDs of A.M Shaikh Homoeopathic Medical college, Hospital and PG research centre, Belgaum.

7.2 METHODS OF COLLECTION OF DATA (INCLUDING SAMPLING PROCEDURES IF ANY):

•  Study design-prospective study of randomized clinical trial.
•  Sample size-minimum 30 in number.
•  Participant subjects-patients aged between 18 to 40yrs irrespective of sex, socioeconomic cultural, educational and literacy background, who fit into inclusion and exclusion criteria.
•  Sampling method- simple random procedure will be adopted with subjects willing to take treatment at above specified clinic.
•  Duration of study- from 10th February 2012 to 30th November 2013.
•  Follow up- follow up of the cases will be done for a minimum period of 6 months to assess prognosis. Cases will be reviewed every month.

INCLUSION CRITERIA FOR STUDY:

1.  Patients of stable plaque psoriasis aged between 18 to 40yrs of age.
2.  Proved cases irrespective of sex, socioeconomic status, and occupation were selected.

EXCLUSION CRITERIA FOR STUDY:

1.  Patients of erythrodermic psoriasis, pustular psoriasis and psoriatic arthropathy.
2.  Cases of diabetes mellitus, seborrhoeic dermatitis, secondary syphilis, cutaneous SLE, paediatric cases.

MATERIAL USED:

1.  Consent form.
2.  Standard proforma sheet, evaluation charts.
3.  Routine clinical examination tools like stethoscope, BP apparatus, thermometer.

RESULT CRITERIA:

•  Recovered
•  Improved
•  Not improved.

7.3 DOES THE STUDY REQUIRE ANY INVESTIGATIONS OR INTERVENTIONS TO BE CONDUCTED ON PATIENTS? IF SO PLEASE DESCRIBE BRIEFLY.

Based purely on clinical diagnosis and Grattage Test at bed side.
In border line cases skin biopsy may be needed.

7.4 HAS ETHICAL CLEARANCE OBTAINED FROM YOUR INSTITUTION .

Yes, the ethical clearance has been obtained from institution.
8. /

LIST OF REFERENCES:

1.  Shah N Siddharth, API textbook Of Medicine-7th Edition, Mumbai: published by Association of Physicians of India (2003). Pp. 1326.
2.  Davidsons Principles and Practice of Medicine- 20th edition, reprint 2006, 2007. Elsevier limited. Pp.1287.
3.  Dearborn M Frederick, Disease Of The Skin (including exanthemata), reprint edition 2006, New Delhi, B. Jain publishers (p) ltd. Pp.124.
4.  Jhar GHG, Forty years practice: New Delhi: published by Indian Books and Periodicals Syndicate. Pp. 276.
5.  Murphy Robin, Homoeopathic Medical Reprtory, Third Revised Edition. New Delhi: B.Jain publishers (p) ltd. 2nd Edition-2011. Pp. 1950.
6.  Schroyens Frederick, Synthesis, Repertorium Homoeopathicum Syntheticum. 9.1 Edition. Jan 2011. (indian edition). New Delhi; B.Jain publishers (p) ltd. Pp. 1857.
7.  Gupta Ramji, Manchanda R.K., Textbook Of Dermatology For Homoeopaths. 4th Edition-2011. New Delhi: B.Jain publishers (p) ltd. Pp.187.
8.  Clarke H John, The Prescriber, Reprint Edition-jan 2009. New Delhi: Indian Books And Periodicals Publishers. Pp.299.
9.  Journal Source, Homoeo Era, Empowering Homoeopaths. Vol: 2, issue-4, may 2011. Printed and published by Dr. E S J Prabhu Kiran. Pp.7.
10.  Internet source: http:// health.hpathy.com/ psoriasis-symptoms-treatment-cure.asp. Download date: 21-10-2011.
9. / SIGNATURE OF CANDIDATE
10. / REMARKS OF THE GUIDE
11. / NAME AND DESIGNATION OF
11.1 GUIDE / DR. NAHIDA.M. MULLA,
M.D.(HOM)MACH
PROF. & GUIDE
DEPT. OF REPERTORY,
A.M. SHAIKH HOMOEOPATHIC MEDICAL COLLEGE, HOSPITAL & P.G. RESEARCH CENTRE,
BELGAUM – 590010.
11.2 SIGNATURE
11.3 CO-GUIDE (if any) / ------
11.4 SIGNATURE / ------
11.5  HEAD OF THE
DEPARTMENT / DR. S.S. PUJAR, M.D.(HOM)
PROF. & H.O.D
DEPT. OF REPERTORY,
A.M. SHAIKH HOMOEOPATHIC MEDICAL COLLEGE, HOSPITAL & P.G. RESEARCH CENTRE,
BELGAUM – 590010.
11.6 SIGNATURE
12. / 12.1 REMARKS OF THE
CHAIRMAN/PRINCIPAL
12.2 SIGNATURE

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