Supplemental Data. Yang Et Al. (2016). Plant Cell 10.1105/Tpc.15.01027

Supplemental Data. Yang et al. (2016). Plant Cell 10.1105/tpc.15.01027

Supplemental Data Set 1:Sequences used for the phylogenetic analysis in Supplemental Figure 6(FASTA format)

>Os-LIR1

MQTAASSVVGLSAVLPAAVKGRSLQIQAPRRVALRVRAAAAAVAVEAAEVDYSSNISVFPMEACDLIGGEACNVQMYPEAKLSSSAAVAVSRAAAEEVDRDYLSYDEPTTVFPEEACDDLGGEFCKAT

>Pt-LIR1

MQAATGLLAVLPVAAARGSRLMVRRRSIVVAGARSVVLRAAATGAAEVDYSSDVSVFPMEACDLVGGEACDAGEMYPETKPGDSAPAVAARTSPEEVEREYLSYDEAKTVFPGEACDDLGGEFCEAPYQTGVSKE

>Zm-LIR1

MQAAATAAGFSAVLPAKGRPAARSRVVARVPATRRSVRVAAVVATEAAQIDYSSSVSVFPMEACDLLGGDACNGPMFPEAKPASAAAAASRSVVGVDRDYLSYDEPKTVFPGEACDDLGGEFCEAPYQDGVSKELAHA

>Lp-LIR1

MQAAIGLPAVLPVAARGSRLAARRRSIVAAGTRRLAGGVVHAAPTGAVEVDYSSDVSVFPMEACDLVGVEACEAAEMYPETKLSDSASAAAASKVEEVEREYLSYDEAKTVFPGEACDDLGGEFCEAPYQTGVSKE

>Bd-LIR1

MQAIVGLSAVVPGTVRVSSSSRPAARRSIVVAMGSGARRTIRACAGAGLTPAAAEVDYSSSVSVFPMEACELVGGEACEAPEMYPETKLSAQDSSSSSGSSPAVAGTSVVEREYLSYDDPKTVFPGEACDDLGGEFCEAPYQTGVSKE

>Hv-LIR1

MMQAAVALSAVLPVAVRCRPAARRSSSATVAGGRRIVGGGGVRASAAAAPEADYSSNVSVFPMEACDLVGGEACDAQMYPETKLGGGAAAAAVARAPEVEREYLAYDEPKTVFPDEACDDLGGEFCEAPYQTSK

>Cs-LIR1-1

MQFQAALSIASPSCSLLPPTAKSMAFSIPTRSMPRQSKGTLKAKASAVGQDPSTVDYSSMSSVFPAEACDTVGGEACDVEMYPEVKLKPEAXKGNSVTEPVEREYLQYDSPKTVFPAEACDDLGGEFCDPEYQKGVY

>Vv-LIR1-1

MQAALCFPRSTLPLLTPTKPFSSLKNPISKLQTSPFPPLRATSKLQETPSTVDYSSTTSVFPAEACEVVGGEACDAEMYPEVKLKAEAGNPPARSATEGVDREYLEYNSPKTVFPGEACDDLGGEFCEPEYQEGVFQEK

>Wa-LIR1-1

MQASALSFAASLPAKIVGSASAHRKLPPGVASRRRSARLPPLSASAQENLTVDYSSSTSVFPAEACETLGGDACAANVFPETKLPPANNSANANKPSSEQIDREYLDYSEPRTVFPDEACDDLGGDFCKPEYQKA

>Ptr-LIR1-1

MQAAIFLTPSILPLVTPNKSLASARRVVPRLQTSKCSPIKASAPVTNDTSTVDYSSFTSVFPAEACETIGGEACNVEMYPEVKLKPDARSTTPSTSEQIDREYLEYNSAKTVFLDEACDDLGGEFCDPGYQG

>Rc-LIR1-1

MQAALHLPPPPLSIVRSATALPWRSIQKFNTTRCSPIRASTPVGNDTSTVDYSSVVSVFPAEACETIGGEVCDVDMYPEVKLKPEAESTTAASTATEHIDREYLQYDSPKTVFLEEACDDLGGEFCDPEYQRP

>Cm-LIR1

MQAALSISPTTLVPLTTSKNFSQVAIYTPKLVGSSLASRRSAIKVAATTSNDPSTFDYNSAFSVFPAEACEVIGGDACSAEMYPEAKLKPEAKNDTSTTASEPIEREYLEYNDTNTVFKGEACDDLGGTFCEREYQRGVY

>Gm-LIR1-1

MQTALTFAAPNVVPLAPTKSVSHITIFPTKLKAPRSSPRYSPIRVATVEPDTSTVDYNSAFSVFPAEACETVGGEACMAEMYPETKLQPEAKTPRVVTENVEREYLEYDDPKTVFRGEACDDLGGTFCETEYQKGVY

>Rc-LIR1-2

MQAALSIAPPVFPVKPSKNLSQVILSPPQLGASSLAPRASPIKAAYATVAYDTSTVDYSSVISVFPAEACETLGGDACLANIFPEVKLEARNDAAAARIASEPIEREYLEYNDAKTVFCAEACDDLGGEFCSREYQRGVY

>Gm-LIR1-2

MQTSLTFAAPNVVPLAQTKSFSHVAIFPTNLKAPRSSPRYSPIRVAIVEPDTSTVDYNSAFSVFPAEACETVGGEACMAEMYPEVKLQPEAKTPRVVTENVEREYLEYDDPKTVFRGEACDDLGGTFCETEYQKGVY

>Can-LIR1

MQAALYFTPSFIPIMTPPKPLISTLMKPISSNLKTNHSTCPPIRATPAANDTSSTVDYSSMTSSVFPAEACETIGGEACDVEMYPETKPKSAENTTKTQVSESVDREYLEYNEPKTVFLGEACDDLGGKFCEAEYQNGVY

>Cme-LIR1

MQLQAALSIAPPSCSLLPPTAKLMAFSIQTSVFPAEACDTVGGEACDVEMYPEVKLKPEAKKGSSVTEPVEREYLQYDSPKTVFPAEACDDLGGEFCDPEYQKGVY

>Car-LIR1

TALTFAPTTTFVPLTAPKSVSHLTTTSFPTKLIAPRYTAVKVATGNSDTPTVDYNSAFSVFPAEACETVGGEACLADMYPEVKLQPEAKNDTPKASENIEREYLDYNDPKTVFQAEACDDLGGTFCEPDYQKGVY

>Th-LIR1

MQGAMSIKPTILLPLPSSQSSPKLTLLLPQSITTTKASRLSSLRPNASSSSSTSDSLTVDYNSLLSVFPAEACETISGYACSADIYPEVKLDTKPVSRPVATTEPVDREYLEYNNPKTVFCAEACDDLGGEFCEPDYQKDVY

>Al-LIR1

MQGSLFIKPTILLPLPSSVSSPKLTFLLPHATKASRLSSLRSNNASSPSTSDPNTVDYNSSLLSVFPAEACEVISGYACSADIYPEVKLDTKPVSRPVASEPVDREYEEYNNPKTVFREEACDDLGGEFCEPGYQKDAN

>Br-LIR1

MQGALCIKPTILPLSSPKLTLLPPQTISTTKPSRLSSLRFRPNSSSPSTSDPLTVDYNDSPLSVFPAEACEVISGYACSADIYPEVKLETKPVSPPVASEPVDREYLEYNNPKTVFPAEACDDLGGEFCEPDYQKDVY

>Psa-LIR1

MQTALTFAATITVVPLTTPKSVSHLTIFPTKFTASRASPPRYTAIKVASGNSDPATVNYNSAFSVFQLEACERFGGEACLADMYPEVKLQPERSNDAPKTAASENIDRDYLEYNDPKTVFQAEACDDLGGTFCEPDYQKGVY

>Vv-LIR1-2

MQAALCFAPTLLPLTPSRNFATPASSSPPKLATSLTSRRPPIKAAAAAYDSSTVDYNSMTSVFPAEACDVIGGEACLADCYPEVRLKQEARNRAARTASEVTERDYYEYNDAKTVFRAEACDDLGGLFCEREYQRGVY

>Mt-LIR1

MQTALTFATTTFVPLTTPKSISHLATNLSFPTKLIASRSSPPRYTAIKVVTDNSDPSTVDYNSAFSVFPAEACETVGGDACLADMNPEVKLQPEARNDTPKTAASGNIEREYLDYNEPKTVFQAEACDDLGGAFCEPDYQKGVY

>Ptr-LIR1-2

MQAAIFLAPPLVPPVTPNKSLASPQRAVSRLQTPNCPPDQSKFTSGKRHLNTEACETIGGEACDVEMYPEVKLKPDARNTPRSTSEQIDREYLEYNSPKKVFQEEACDDLGGEFCDPGYQG

>At-LIR1

MQGALFIKPTILLPLPSSVSSPKLTFLLPHATKASRLSSLRSNNSSSSSSLTSDPNTVDYNSSILSVFPAEACEVISGYACSADIYPEVKLDTKPVSRPVASEPVDREYEEYNSPKTVFREEACDDLGGEFCEPDFQKDAN

>Pa-LIR1

STITLTKNVRRFSQHRWRAMATNPTVDYDSSAKSVFPAEACDTVGGEACEGEIGAEVTLKVDSPPTSSPGVGIDREYVEYASEQKTVFPGEACDDLGGEFCEPEYQSGVYKEKEPAK

>Psi-LIR1-1

MQATLALSFSASWPILPHTHHKPLPLSTITLTKNVRRFSQHRWRAMATNPTVDYDSSAKSVFPAEACDTVGGEACEGEIGAEVTLKVDSPPTSSPGVGIDREYVEYASELKTVFPGEACDDLGGEFCEPEYQSGVYKEKEPAK

>Psi-LIR1-2

MQATLALSFSASWPILPHTHHKPLPLSTITLTKNVRRFSQHRWRAMATNPTVDYDSSAKSVFPAEACDTVGGEACEGEIGAEVTLKVDLPPTSSPGVGIDREYVEYASEQKTVFPGEACDDLGGEFCEPEYQSGVYKEKEPAK

>Pp-LIR1

MQHTGSPLLSFMAQQGSSHSPQAPTAGTIRLTKNFQRFSQHRWRAMAENPTVDYDSSAKSVFPAEACDTVGGEACEGEIGVEVTLKADSPSPSSPPAEGVDREYVEYASEKKTVFPGEACDDLGGDSASQNIRVALQREQPAK

>Sb-LIR1

MQAAATAVGFSAVLPVKARPAARSTAVARVPATRRSVRTAAAAVVVAEPAEVDYSSSFSVFPMEACDLLGGDACIGKMFPEAKLAAAAPEASRRVDAVERDYLSYDGPKTVFPGEACDDLGGEFCEAPYMDGVSRDA

>Cp-LIR1

MQSALFISPPTLPLTPSKNFSQQTISPPRLSGSVASRRFSTKATTPCETSTVDYSSAISVFPAEACETIGGDACLADIFPEVKLNPEASSKRIASEPFDRDYLEYNDPKTVFRGEACDDLGGEFCSPDYERGA

>St-LIR1

MQAALFFTTSSIPLVKPPNPLATSPLRCVSTHLKITHIKATPVDTSTVDYSSMNSSVFPAEACEIIGGEACDVEMYPETKPKSTPSATASSNTPSTESVDREYLAYNEPKTVFLSEACDDLGGEFCEADYQTGVY

>Sl-LIR1

MQAALFLTSIPLVKPPKPLTTSPLRCVSTHLKITHIKATPIDTSTVDYSSMNSSVFPAEACETIGGETCDVEMYPETKPKSTPSSKTLSMESVDREYLAYNEPKTVFLSEACDDLGGEFCEAKYQTGVY

>Sle-LIR1

LQAQPSNQQYVDYAGNQSVFPAEACEELGGDSCAAEGVGPEVKLNPTTPPKLASAAQKKQQPEREYVDYESGNKTVFPGEACDDLGGEFCEGDYQKDVFPEK

>Ss-LIR1

RVRAQAQASGKPSSDQYVDYEGRNSVFPAEACEDTGENCDAEGFFKEVLPSASATPVTPAAQKPGLDREYEEYAGSKTVFPGEACEELGGEFCDPEFQEGVFPEKAQASKK

>Cat-LIR1

VKSHSSRGASSPAQALFGGGKKKQAEEYVEYDKQDESVFPDEACDDLGGEFCEPDWREKNNVGKEVRSEAQPRQRNNSSKDEPDRDYVNYESSNKTVFPGEACDDLGGEFCEPDYQEGVGKE

>Cv-LIR1

VRAQSSSSEPPLYIGYDPKKTVFPAEACDELGGEFCNVEGVGEEVNPQTSGAAAEEQPQAAPTGMFASIFGKGAAEIPDREYVQYDSTKTVFPGEACDDLGGEFCAPDFQEGVFPD

>Bt-LIR1

KSSEQQYVDYEGRSSVFPAEACEETGEGCDAEGLFKEALPRASATPIAAAQKPGPDREYEEYKGAKTVFPGDACDELGGEFCEPEFQEGVFPDKVQASKK

>Tle-LIR1

RPVIVQSQPQEQEYVNYTGKQSVFPAEACEDVGGDACVVEGVGPEVKPKAAVAKEAPKAAEGPDREYVDYVTEKKTVFPGEACDELGGEFCEEDFQKGVFPDK

Alignment used for the phylogenetic analysis in Supplemental Figure 6(in PHYLIP format)

40 189

Os-LIR1 -MQTAASSVV GLSAVLPAAV KGRSLQI--- --QAPRRVAL RVRAAAAAVA V------

Sb-LIR1 --MQAAATAV GFSAVLPVKA RP------AARSTAVA RVPATRRSVR TAAAAVVVA-

Zm-LIR1 --MQAAATAA GFSAVLPAKG RP------AARSRVVA RVPATRRSVR VAAVVAT---

Hv-LIR1 -MMQAAVALS ---AVLPVAV RCRP------AARRSSSA TVAGGRRIVG GGGVRASAA-

Bd-LIR1 --MQAIVGLS ---AVVPGTV RVSSSSRP-- --AARRSIVV AMGSGARRTI RACAGAGLTP

Lp-LIR1 --MQAAIG-- -LPAVLPVAA RGSRL------AARRRSIV AAGTRRLAGG VVHAAPT---

Pt-LIR1 --MQAATGLL ---AVLPVAA ARGS------RLMVRRRS IVVAGARSVV LRAAAT----

Can-LIR1 --MQAALYFT --PSFIPIMT PPKPLISTL- --MKPISSNL KTNH-STCPP IRATPAAND-

St-LIR1 --MQAALFFT -TSSIPLVKP PN------PLATSPLR CVSTHLKITH IKATPV----

Sl-LIR1 --MQAALFLT SIPLVKPPKP ------LTTSPLR CVSTHLKITH IKATPI----

Al-LIR1 --MQGSLFIK -PTILLPLPS SVSSPKLTF- --LLPHATKA SRLSSLRSNN ASSPSTS---

At-LIR1 --MQGALFIK -PTILLPLPS SVSSPKLTF- --LLPHATKA SRLSSLRSNN SSSSSSLTS-

Th-LIR1 --MQGAMSIK -PTILLPLPS -SQSSPKLT- --LLLPQSIT TTKA-SRLSS LRPNASSSSS

Br-LIR1 --MQGALCIK --PTILPLSS PKLT------LLPPQTIS TTKP-SRLSS LRFRPNSSSP

Pp-LIR1 --MQHTGSPL -LSFMAQQGS -SHSPQAPTA GTIRLTKNFQ RFSQ-HRWRA MA------

Psi-LIR1-1 --MQATLALS -FSASWPILP HTHHKPLPLS T-ITLTKNVR RFSQ-HRWRA MA------

Psi-LIR1-2 --MQATLALS -FSASWPILP HTHHKPLPLS T-ITLTKNVR RFSQ-HRWRA MA------

Pa-LIR1 --ST------ITLTKNVR RFSQ-HRWRAMA------

Vv-LIR1-2 --MQAALCFA --PTLLPLTP -SRNFATPAS --SSPPKLAT SLT--SRRPP IKAAAAAY--

Vv-LIR1-1 --MQAALCFP -RSTLPLLTP -TKPF------SSLKNPIS KLQT-SPFPP LRATSKLQE-

Cs-LIR1-1 MQFQAALSIA -SPSCSLLPP TAKSMAF--- --SIPTRSMP RQSKGTLKAK ASAVGQ----

Cme-LIR1 MQLQAALSIA -PPSCSLLPP ------

Rc-LIR1-1 --MQAALHLP -PPPLSIVRS -ATAL------PWRSIQ KFNT-TRCSP IRASTPVGN-

Ptr-LIR1-2 --MQAAIFLA -PPLVPPVTP -NKSL------ASPQRAVS RLQT-PNC------

Ptr-LIR1-1 --MQAAIFLT --PSILPLVT PNKS------LASARRVV PRLQTSKCSP IKASAPVTN-

Rc-LIR1-2 --MQAALSIA -PPVF-PVKP -SKNLSQVI- --LSPPQLGA SSLA-PRASP IKAAYATVAY

Cp-LIR1 --MQSALFIS --PPTLPLTP -SKNFSQQT- --ISPPRLSG SVAS-RRFST KATTPC----

Cm-LIR1 --MQAALSIS -PTTLVPLTT -SKNFSQVA- --IYTPKLVG SSLA-SRRSA IKVAATTSN-

Gm-LIR1-1 --MQTALTFA -APNVVPLAP -TKSVSHIT- --IFPTKLKA PRSS-PRYSP IRVATVEP--

Gm-LIR1-2 --MQTSLTFA -APNVVPLAQ -TKSFSHVA- --IFPTNLKA PRSS-PRYSP IRVAIVEP--

Psa-LIR1 --MQTALTFA ATITVVPLTT -PKSVSHLT- --IFPTKFTA SRASPPRYTA IKVASGNS--

Car-LIR1 ----TALTFA PTTTFVPLTA -PKSVSHLTT T-SFPTKLIA -----PRYTA VKVATGNS--

Mt-LIR1 --MQTALTFA -TTTFVPLTT -PKSISHLAT NLSFPTKLIA SRSSPPRYTA IKVVTDNS--

Wa-LIR1-1 MQASALSFAA SLPAKIVGSA SAHR------KLPPGVAS RRRS-ARLPP LSASAQ----

Cat-LIR1 ------VKSHS SRGASSPAQA LFGGGKKKQ-

Ss-LIR1 -RVRAQAQAS GKPS------

Bt-LIR1 --KSS------

Cv-LIR1 --VRAQSSSS EPPL------

Tle-LIR1 ------RPVIVQSQP Q------

Sle-LIR1 --LQAQPS------

---EAAEVDY -SSNISVFPM EACDLIGGEA CNV------Q MYPEAKLSSS AAVA-VSRAA

---EPAEVDY -SSSFSVFPM EACDLLGGDA CIG------K MFPEAKLAAA APEA-SRRVD

---EAAQIDY -SSSVSVFPM EACDLLGGDA CNG------P MFPEAKPASA AAAA-SRSVV

---AAPEADY -SSNVSVFPM EACDLVGGEA CDA------Q MYPETKLGGG AAAA-AVARA

---AAAEVDY -SSSVSVFPM EACELVGGEA CEAP-----E MYPETKLSAQ DSSS-SSGSS

---GAVEVDY -SSDVSVFPM EACDLVGVEA CEAA-----E MYPETKLSDS ASAAAASK--

---GAAEVDY -SSDVSVFPM EACDLVGGEA CDAG-----E MYPETKPGDS APAV-AARTS

---TSSTVDY SSMTSSVFPA EACETIGGEA CDV------E MYPETKPKSA EN---TTKTQ

---DTSTVDY SSMNSSVFPA EACEIIGGEA CDV------E MYPETKPKST PSATASSNTP

---DTSTVDY SSMNSSVFPA EACETIGGET CDV------E MYPETKPKST PSSK-TLS--

---DPNTVDY NSSLLSVFPA EACEVISGYA CSA------D IYPEVKLDTK PVSR-PVA--

---DPNTVDY NSSILSVFPA EACEVISGYA CSA------D IYPEVKLDTK PVSR-PVA--

TS-DSLTVDY -NSLLSVFPA EACETISGYA CSA------D IYPEVKLDTK PVSR-PVAT-

STSDPLTVDY NDSPLSVFPA EACEVISGYA CSA------D IYPEVKLETK PVSP-PVA--

---ENPTVDY DSSAKSVFPA EACDTVGGEA CEG------E IGVEVTLKAD SPSP-SSP--

---TNPTVDY DSSAKSVFPA EACDTVGGEA CEG------E IGAEVTLKVD SPPT-SSPGV

---TNPTVDY DSSAKSVFPA EACDTVGGEA CEG------E IGAEVTLKVD LPPT-SSPGV

---TNPTVDY DSSAKSVFPA EACDTVGGEA CEG------E IGAEVTLKVD SPPT-SSPGV

---DSSTVDY -NSMTSVFPA EACDVIGGEA CLA------D CYPEVRLKQE ARNR-AAR-T

---TPSTVDY -SSTTSVFPA EACEVVGGEA CDA------E MYPEVKLKAE AGNP-PARS-

---DPSTVDY -SSMSSVFPA EACDTVGGEA CDV------E MYPEVKLKPE AXKG-NSV--

---TAKLMAF -SIQTSVFPA EACDTVGGEA CDV------E MYPEVKLKPE AKKG-SSV--

---DTSTVDY -SSVVSVFPA EACETIGGEV CDV------D MYPEVKLKPE AEST-TAAST

---PPDQSKF -TSGKRHLNT EACETIGGEA CDV------E MYPEVKLKPD ARNT-PRST-

---DTSTVDY -SSFTSVFPA EACETIGGEA CNV------E MYPEVKLKPD ARST-TPST-

---DTSTVDY -SSVISVFPA EACETLGGDA CLA------N IFPEVKLEAR NDAA-AAR-I

---ETSTVDY -SSAISVFPA EACETIGGDA CLA------D IFPEVKLNPE ASSK-RIA--

---DPSTFDY -NSAFSVFPA EACEVIGGDA CSA------E MYPEAKLKPE AKND-TST-T

---DTSTVDY -NSAFSVFPA EACETVGGEA CMA------E MYPETKLQPE AKTP-RVV--

---DTSTVDY -NSAFSVFPA EACETVGGEA CMA------E MYPEVKLQPE AKTP-RVV--

---DPATVNY -NSAFSVFQL EACERFGGEA CLA------D MYPEVKLQPE RSND-APKTA

---DTPTVDY -NSAFSVFPA EACETVGGEA CLA------D MYPEVKLQPE AKND-TPKA-

---DPSTVDY -NSAFSVFPA EACETVGGDA CLA------D MNPEVKLQPE ARND-TPKTA

---ENLTVDY -SSSTSVFPA EACETLGGDA CAA------N VFPETKLPPA NNSA-NANKP

---AEEYVEY DKQDESVFPD EACDDLGGEF CEPDWREKNN VGKEVRSEAQ PRQRNNSS--

---SDQYVDY -EGRNSVFPA EACEDT-GEN CDAE-----G FFKEVLPSAS ATPV-TPAAQ

---EQQYVDY -EGRSSVFPA EACEET-GEG CDAE-----G LFKEALPRAS --AT-PIAAA

------YIGY -DPKKTVFPA EACDELGGEF CNVE-----G VGEEVNPQTS GAAA-EEQPQ

---EQEYVNY -TGKQSVFPA EACEDVGGDA CVVE-----G VGPEVKPKAA VAKE-APKA-

---NQQYVDY -AGNQSVFPA EACEELGGDS CAAE-----G VGPEVKLNPT TPPKLASAAQ

A-----EE------VDRDYLSY -DEPTTVFPE EACDDLGGEF CKAT------

A------VERDYLSY -DGPKTVFPG EACDDLGGEF CEAPYMDGVS

G------VDRDYLSY -DEPKTVFPG EACDDLGGEF CEAPYQDGVS

P------E------VEREYLAY -DEPKTVFPD EACDDLGGEF CEAPYQTSK-

PAVAGTSV------VEREYLSY -DDPKTVFPG EACDDLGGEF CEAPYQTGVS

-----VEE------VEREYLSY -DEAKTVFPG EACDDLGGEF CEAPYQTGVS

P-----EE------VEREYLSY -DEAKTVFPG EACDDLGGEF CEAPYQTGVS

V----SES------VDREYLEY -NEPKTVFLG EACDDLGGKF CEAEYQNGVY

S----TES------VDREYLAY -NEPKTVFLS EACDDLGGEF CEADYQTGVY

-----MES------VDREYLAY -NEPKTVFLS EACDDLGGEF CEAKYQTGVY

-----SEP------VDREYEEY -NNPKTVFRE EACDDLGGEF CEPGYQKDAN

-----SEP------VDREYEEY -NSPKTVFRE EACDDLGGEF CEPDFQKDAN

-----TEP------VDREYLEY -NNPKTVFCA EACDDLGGEF CEPDYQKDVY

-----SEP------VDREYLEY -NNPKTVFPA EACDDLGGEF CEPDYQKDVY

P----AEG------VDREYVEY ASEKKTVFPG EACDDLGGDS ASQNIRVALQ

G------IDREYVEY ASELKTVFPG EACDDLGGEF CEPEYQSGVY

G------IDREYVEY ASEQKTVFPG EACDDLGGEF CEPEYQSGVY

A----SEV------TERDYYEY -NDAKTVFRA EACDDLGGLF CEREYQRGVY

A----TEG------VDREYLEY -NSPKTVFPG EACDDLGGEF CEPEYQEGVF

-----TEP------VEREYLQY -DSPKTVFPA EACDDLGGEF CDPEYQKGVY

A----TEH------IDREYLQY -DSPKTVFLE EACDDLGGEF CDPEYQRP--

-----SEQ------IDREYLEY -NSPKKVFQE EACDDLGGEF CDPGYQG---

-----SEQ------IDREYLEY -NSAKTVFLD EACDDLGGEF CDPGYQG---

A----SEP------IEREYLEY -NDAKTVFCA EACDDLGGEF CSREYQRGVY

-----SEP------FDRDYLEY -NDPKTVFRG EACDDLGGEF CSPDYERGA-

A----SEP------IEREYLEY -NDTNTVFKG EACDDLGGTF CEREYQRGVY

-----TEN------VEREYLEY -DDPKTVFRG EACDDLGGTF CETEYQKGVY

A----SEN------IDRDYLEY -NDPKTVFQA EACDDLGGTF CEPDYQKGVY

-----SEN------IEREYLDY -NDPKTVFQA EACDDLGGTF CEPDYQKGVY

A----SGN------IEREYLDY -NEPKTVFQA EACDDLGGAF CEPDYQKGVY

S----SEQ------IDREYLDY -SEPRTVFPD EACDDLGGDF CKPEYQKA--

-----KDE------PDRDYVNY ESSNKTVFPG EACDDLGGEF CEPDYQEGVG

-----KPG------LDREYEEY -AGSKTVFPG EACEELGGEF CDPEFQEGVF

Q----KPG------PDREYEEY -KGAKTVFPG DACDELGGEF CEPEFQEGVF

A----APTGM FASIFGKGAA EIPDREYVQY -DSTKTVFPG EACDDLGGEF CAPDFQEGVF

-----AEG------PDREYVDY VTEKKTVFPG EACDELGGEF CEEDFQKGVF

K----KQQ------PEREYVDY ESGNKTVFPG EACDDLGGEF CEGDYQKDVF

------

RDA------

KELAHA---

------

KE------

------

REQPAK---

KEKEPAK--

------

QEK------

------

KE------

PEKAQASKK

PDKVQASKK

PD------

PDK------

PEK------