Ancillary Studies Registry: Funded Look AHEAD Ancillary Studies

Status as of 11/04/2016

Title, Grant Number, Status / Investigator
Impact of the SHOW study interventions on vascular reactivity and endothelial function
Funded internally [no grant number] (Discontinued; too close to primary study outcome) / Edward Horton, MD and Judith Regensteiner, PhD, MD
Prevalence of two eating disorders
R01 DK60432 (Closed) / Albert Stunkard, MD and Scott Crow, MD
MRI derived organ & tissue mass changes with weight loss
HL70298 (Data collection completed in 2007. Ongoing data analysis and manuscript writing)
Project Period: NCE 2001 - 2007 / Dympna Gallagher, EdD
Biomarkers of oxidative stress in SHOW participants
7RO1 HL70300 (no more interaction with subjects. Ongoing for measurements in samples and data analysis). / Dawn C. Schwenke, PhD
Fat cell size, muscle lipid infiltration and insulin resistance
5 R01 DK060412 (Closed) / Eric Ravussin, PhD
Nonalcoholic fatty liver disease (NAFLD) and hepatic energy homeostasis in overweight diabetic adults
R01 DK060427 (Closed)
Project Period: 09/15/2001 - 07/31/2006 / Anna Mae Diehl, with J.M. Clark, L. Cheskin, V.P. Chacko, F.L. Brancati
Sexual dysfunction in male and female patients with type 2 diabetes mellitus: Intervention effects
5R01DK060438-03 (Closed) / Raymond C. Rosen, PhD, Stephen Schneider, MD
Heavy metals and cardiovascular risk in obese type II diabetes mellitus patients
HL070299 (Completed)
Final data collection date for primary outcome measure: August 2007 / Eliseo Guallar, MD, DrPH
Effects of weight loss on obstructive sleep apnea
HL070301 (Closed) / Gary D. Foster, PhD
Doing and Saying: Do behavioral intentions and health behaviors change during one year of weight man
Grant number and status unavailable at this time. / Donald A. Williamson, PhD
Cultural differences in perceptions, attitudes, and behaviors related to nutrition and weight
HL084700 (Closed) / Tiffany L. Gary, PhD
Obesity, inflammation, and thrombosis
R01-HL090514-01 (Closed)
05/01/2007 – 04/30/2012 / Christie Ballantyne, MD
G protein-coupled receptor variants as genetic determinants of obesity
R01 DK072497 (Closed) / Alan S. Kopin, MD; Gordon Huggins, MD
Effects of social determinants of health on diabetes self-care and subsequent health outcomes
5 U01-DK057177-10 (Ongoing-manuscript writing but no longer collecting data) / Gina Evans, PhD; John Foreyt, PhD; Rebecca Reeves, DrPH
Intentional weight reduction and physical and cognitive function
R01AG033087 (9/30/09-8/31/14; Data Analysis complete. Field operations complete.) / Stephen B. Kritchevsky, PhD
Genetic and behavioral effects on high-density lipoprotein cholesterol: The Look AHEAD Study
5 R01 DK090043-02 (Closed) / Jeanne McCaffery, PhD
BNP determinants of brain natriuretic peptide in diabetes
R21HL089686 (Closed) / Alain Bertoni, MD
The Look AHEAD Brain Study
5R01DK092237-04 (Funding has ended; data analysis and publication activities continue) / Mark Espeland, PhD
Gene behavioral interactions and weight loss
3 U01 DK056992-14S1 (Closed) / Jeanne McCaffery, PhD
Genetics of diabetic nephropathy
DiaComp Pilot and Feasibility Award
#25034-34 (Closed) / Jeanne McCaffery, PhD
Diabetes inflammatory markers and urinary incontinence in women
NIDDK/DiaCOMP U24;DK076169(SubcontractPI; PI: McIndoe, R);09/01/2013 -08/30/2014
Analyses ongoing (in the queue to be done at the DCC). Funding completed. / LesleeSubak, MD
Understanding Racial and Ethnic Differences in Weight Loss Maintenance and Regain
1R03DK101795-01 (Ongoing)
No cost extension through 03/31/2017 / Gareth R. Dutton, PhD
Metabolomic biomarkers predictors of long-term success following bariatric surgery
1R01DK108580-01 (Ongoing) / BlandineLafarrere, MD
Salivary amylase gene AMY1 as predictor of weight and diet in Look AHEAD and DPP
R21DK109225 (Ongoing)
Project Period: 04/01/2016 – 03/31/2018 / Jeanne McCaffery, PhD
The long-term benefits of interventions to improve T2D outcomes
1R01DK107552-01A1
(Received notice of award.) / Dana Goldman, PhD; Peter Huckfeldt, PhD