Al Balqa Applied University
Faculty of Medicine
Fall 2017
Biochemistry For Medical Students
( 31501221 )
Instructors:
1. Dr. Nabil Amer MD, PhD
E-mail:
Office hours : Sunday, Tuesday & Thursday from 11-1
2. Professor Nabil Bashir MSc, PhD
E-mail:
Office hours :Sunday, Tuesday & Thursday from 11-1
Schedule:
Section / Place / Time / Day1 / Auditorium 1 / 8:00-9:00 / Sunday, Tuesday and Thursday
Course Description and General Objectives:
This course is designed to explore biochemical and molecular basis of life. Course content reflects subjects such as the following: behavior of proteins; the structure and function of hemoglobin and enzymes, and the metabolism of macromolecules, metabolic pathways of small molecules, and the integration of metabolism within and between tissues, cell communication strategies such as hormonal communication . Case studies will be routinely applied to integrate biochemical, and cellular contributions to enhance our understanding of systemic pathology. Nutrition will be discussed in the context of biochemistry and metabolic pathways.
By the end of this course, students should be able to
1. Describe the process by which various biomolecules are synthesized and how they function.
2. Describe the manner in which biological energy is stored, recovered and generated
3. Integrate overlapping pathways of metabolism within a variety of tissues.
Methods Of Instruction
Lectures
Evaluation and Distribution of Marks
Mid-term Exam : 50 % on 12/11/2017 (10-12)
Final Comprehensive Exam: 50 %, to be announced later
Recommended Textbooks:
1. Biochemistry by Mary campbell & Shawn Farrell, Eight Ed. 2016 ,Thomas Books/Cole
ISBN 0-534-39499-X
2. Lippincott’s illustrated reviews in Biochemistry by Ferrier. 6th Edition
LEARNER OUTCOMES
The intention of the course is for students to:
1 Acquire the technical language used to communicate biochemistry information and use that language to describe proteins, molecules, signaling pathways, catalysis, and metabolism accurately
2 Recall key elements of basic biochemistry principles, including metabolic pathways, molecule names, molecular structures (as noted), enzyme/cellular control mechanisms, catalysis, and signaling pathways
3 Perform analyses relevant to the material presented
4 Communicate key concepts relevant to biochemistry
5 Understand and apply general concepts of biochemistry to relevant, specific problems.
6 Predict the directions of metabolic pathways from an understanding of the control mechanisms and energy considerations of biochemical reactions.
Detailed Syllabus
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Lecture # / Title Of Lectures / Day / Date / Instructor1 / The Behavior of Proteins: Hemoglobin / SUN / 17/9 / N.BASHIR
2 / The Behavior of Proteins: Enzymes I / TUES / 19/9 / N.BASHIR
VACATION / THUS / 21/9
3 / Enzymes II / SUN / 24/9 / N.BASHIR
4 / Enzymes III / TUES / 26/9 / N.BASHIR
5 / Catalytic Strategies I / THUS / 28/9 / N.BASHIR
6 / Catalytic Strategies II / SUN / 1/10 / N.BASHIR
7 / Allostery and Regulation I / TUES / 3/10 / N.BASHIR
8 / Allostery and Regulation II / THUS / 5/10 / N.BASHIR
9 / Carbohydrates Chemistry Revision / SUN / 8/10 / N.BASHIR
10 / Metabolic Energy I / TUES / 10/10 / N.BASHIR
11 / Metabolic Energy II / THUS / 12/10 / N.BASHIR
12 / Glycolysis I / SUN / 15/10 / N.BASHIR
13 / Glycolysis II / TUES / 17/10 / N.BASHIR
14 / Gluconeogenesis / THUS / 19/10 / N.BASHIR
15 / PPP / SUN / 22/10 / N.BASHIR
16 / Glycogen Metabolism I / TUES / 24/10 / N.BASHIR
17 / Glycogen Metabolism II / THUS / 26/10 / N.BASHIR
18 / Sugar Metabolism Regulation / SUN / 29/10 / N.BASHIR
19 / Revision / TUES / 31/10 / N.BASHIR
20 / TCA cycle / THUS / 2/11 / N.AMER
21 / Electron transport chain and oxidative phosphorylation / SUN / 5/11 / N.AMER
22 / Electron transport chain and oxidative phosphorylation / TUES / 7/11 / N.AMER
23 / Lipids Chemistry Revision / THUS / 9/11 / N.AMER
24 / MID-TERM EXAM 50 Marks
Academy Rooms No. 101,102,103,104,105,106 / SUN / 12/11
25 / Exam Feed-back revision / TUES / 14/11 / N.AMER
26 / Fatty acid oxidation / THUS / 16/11 / N.AMER
27 / Fatty acid synthesis / SUN / 19/11 / N.AMER
28 / Ketone bodies / TUES / 21/11 / N.AMER
29 / Cholesterol and bile acid metabolism / THUS / 23/11 / N.AMER
30 / Lipoproteins / SUN / 26/11 / N.AMER
31 / Nitrogen balance and urea cycle / TUES / 28/11 / N.AMER
32 / Amino acid degradation / THUS / 30/11 / N.AMER
33 / Amino acid synthesis / SUN / 3/12 / N.AMER
34 / Conversion of amino acids into specialized products / TUES / 5/12 / N.AMER
35 / Nucleotide metabolism 1 / THUS / 7/12 / N.AMER
36 / Nucleotide metabolism 2 / SUN / 10/12 / N.AMER
37 / Vitamins – water soluble / TUES / 12/12 / N.AMER
38 / Feed. fast cycle, insulin and glucagon. / THUS / 14/12 / N.AMER
39 / Integration of Metabolism / SUN / 17/12 / N.AMER
40 / Obesity & diabetes / TUES / 19/12 / N.AMER
41 / Revision / THUS / 21/12 / N.AMER
42 / FINAL EXAM To Be Announced Later According To Academic Calendar.
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