XIX-QIP IN DIPSAR, DELHI
RECENT DEVELOPMENT IN PHARMACEUTICAL CHEMISTRY
A quality improvement program on topic Recent Development in Pharmaceutical Chemistry was organized on 9th March 2015 to 20th March 2015 by DIPSAR Delhi. Days aimed to provide an insight to the fellow pharmacy teachers working across the country about the recent development in various facts of health-care profession .Also to provide the information regarding drug designing and synthesis by applying newer techniques.
The two week QIP was co -ordinate by Dr. Sharad Wokade , with the help of Mrs. Amrita Parle & Dr.R.b.Bodla.
First day
(1)Inaugural session –
The inauguration ceremony was done by Dr.P.D.Sethi -Chairman, Ayurvedic Pharmacopeia of India, shared few upcoming activities in analytical techniques for analysis of multi component drug formulation.
Dr.D.P.Pathak in his welcome speech highlighted the importance and objective of organizing Faculty Development Program.
(2)Lecture by – Dr Ramesh Bodla (Assistant Professor,DIPSAR)
Topic-Protocol for Drug Discovery
A road map to drug discovery and development.
(3)Lecture by-Dr. Rajni Mathur (Assistant Professor,DIPSAR)
Topic-Aqueous extract of leaves Psidium Guajava for inhibit hepatic GLUT-2.
Explain about the most common cause of childhood overweight and obesity and prevention. The high fructose intake raise the circulating level of insulin and leptin and hepatic GLUT-2 expression to promote insulin resistance, dyslipidemia and hypertension that favorably reset with PG.
Second day
(1)Lecture by- Professor (Dr.) D. P. Pathak (Director DIPSAR)
Topic-Nitric oxide: Biological Significance and Detection.
Provided the information about the role of NO in Nervous system, circulatory system, muscular system, immune system and digestive system in human body.
(2)Lecture by- Dr. Devendra Pathak(Director Rajiv Academy for Pharmacy- Mathura)
Topic –Rational use of steroid drugs
Awareness to steroids use and misuse.
(3)Lecture by-Dr.Manish S.Lavhale( Pharmazz India Pvt. Limited , Greater Noida )
Topic- Discovery and Development of Centhaquin.
As a resuscitative agent in hypovolemic shock.
Third day
(1)Lecture by Dr. Jainendra Jain (Director ,Ram-Eesh Institute of Vocational and Technical Education,3, Knowledge Park I, Greater Noida.)
Topic-Molecular docking interactions in Computer Aided Drug Design.(protein ligands docking)
He discuss about the Introduction to protein-ligands docking, Practical aspects, searching for pose, Scoring functions , Assessing performance and the various new software’s use in drug discovery .
(2)Visit to- Animal House in DIPSAR
(3)Demo - Zeta Potential Analyzer(Dispersion Tech-Version5.10)
Is the powerful tool in understanding the stability of a particular suspension .It is used for the Measurement of Molecular size, Particle size, Molecular weight, Zeta potential, Protein mobility, Microrheology. The Particle size range from 0.3nm to 10µm.
(4) Demo –Homogenizer (GEA Niro Soavi Technical Datasheet Laboratory Homogenizer)
This equipment used for thehomogenizationof various types of material, such as tissue, plant food, soil, and many others.
Fourth day
(1)Lecture by-Dr.Vijay Bhalla (Director-Lloyd School of Pharmacy,Treasurer-IPGA)
Topic- Microbial Resistance to Antibiotics, Role of Community Pharmacists
Give the tip to avoid the resistance to antibiotics .Avoid misuse of antibiotic, Avoid self prescription, Do not useantibioticsin viral or other infections ,Takeantibioticsin doctors supervision ,Complete the course ofantibioticseven if you feel better, Do not miss any dose, Do not save any drug for your next time treatment, Do not demandantibioticsfrommedical storesdirectly, Do not takeantibioticswhich are prescribed for your relatives
(2)Lecture by-Dr. Sayeed Ahmad(Associate Professor; Bioactive Natural Product Laboratory Department of Pharmacognosy & Phytochemistry ,Jamia Hamdard ,New Delhi )
Topic- HPTLC- Planar Chromatography in Drug discovery
(3)Demo-HPLC
(4)Demo –CHNSO Analyzer.
Fifth day
(1)Lecture by-Dr. Deepti Jain (Associate Professor, School of Pharmaceutical Sciences, RGPV Bhopal )
Topic-FTNIR: A Versatile Tool for Pharmaceutical Analysis.
A New spectroscopy technique for determination of impurities, it can apply directly to incoming raw material at loaded dock. Can be use to determine the moisture content, content uniformity, tablet API etc.
(2)Lecture by-Dr.S.K.Jain (Professor and Director ,Sagar Institute of Research & Technology –Pharmacy Bhopal)
Topic-Role of Bioinformatics in Identifying New Molecule Targets for Drug Discovery.
Bioinformatics deals with the exponential growth in biological data has led to the development of primary and secondary databases of nucleic acid sequences, protein sequences and structures. Some of the databases include GenBank, SWISS-PROT, PDB, PIR, SCOP, CATH, etc. These databases are available as public domain information and hosted on various Internet servers across the world. Basic research and modeling is done using these databases with the help sequence analysis tools like BLAST, FASTA, CLUSTALW, etc., and the modelled structures are visualized using visualization tools such as WebLab, MOLMOL, Rasmol, etc.
(3)Lecture by-Dr. Amit Bhargava (Oncologist-Batra Hospital and Medical Research Centre New Delhi )
Topic- Hematopoietic Stem Cell Transplantation.
Provided the information for Hematopoietic stem cell transplantation.(HSCT) is the transplantation ofmultipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood. It may beautologous(the patient's own stem cells are used) orallogeneic(the stem cells come from a donor). It is a medical procedure in the field ofhematology, most often performed for patients with certaincancersof thebloodorbone marrow, such asmultiple myelomaorleukemia.
(4) Lecture by- Dr. Anil Thakwani (Senior Consultant,Department of Radiation oncology,Batra Hospital and Medical Research Centre, New Delhi )
Topic -Recent advances in radiotherapy and radio surgery
Sixth day
(1)Lecture by- Dr Y. Kumar (Guest Lecturer in DIPSAR)
Topic- Calculation of λmax and use of shift reagents in UV-Visible Spectrophotometry.
(2)Visit – INMASS-DRDO, Delhi (Guided by Dr. Aseem Bhatnagar)
Institute of Nuclear Medicine and Allied Sciences (INMAS), Delhi under the aegis of Defence Research and Development Organization (DRDO), is engaged in research and developmental work in radiation sciences, Neuro-Computing and Medical Image Processing.
Seventh day
(1)Visit- Jamia Hamdard ,New Delhi
Here Dr. Sayeed Ahmad given the demonstration of HPTLC and other instruments.
(2)Visit - Jubilant Chemsys Limited (B Block, Sector 58, Noida)
The company is a part of Jubilant Drug Discovery and Development Services, under the flagship of Jubilant Life Science Limited, offers services in synthetic, organic and medicinal chemistry areas to various pharmaceutical and biotechnology.
Eighth day
(1)Lecture by-Nitin K. Jain(Scientist –E, Department of Biotechnology ,Ministry Of Science & Technology)
Topic- Protecting Pharmaceutical/Biotechnology Inventions
(2)Lecture by- Prof. B.Narasimhan (Head & Dean ,Faculty of Pharmaceutical Science NDV,Rohtak)
Topic-QSAR by Hansch Analysis.
(3)Lecture by-Dr. Sharad Wokade (Assistant Professor, DIPSAR)
Topic- Drug Discovery & Animal House Management
(5)Lecture by-Dr.Mohammad Shaquiquzzman(Associate Professor, Jamia Hamdard ,New Delhi )
Topic-Handling of NMR in Pharmacy
Ninth day
(1)Lecture by-Mr. Abhishekh Jain (CEO,Grace Wellness)
Topic-Stress Management
(2)Lecture by-Dr. Milind Parle(Dean, Faculty of Medical Science,HISAR, Haryana)
Topic- Fundamental Elements of Research.
(3)Lecture by-Dr. Poonam Pipalini (Professor-Panjab University ,Chandigarh)
Topic-Alzheimer’s disease ,The Mystery Unfold……………..
(4) Lecture by –Dr.Thirmurthy Velpandian (Department of Ocular Pharmacology and Pharmcy,AIIMS,Delhi)
Topic-pK of Antimicrobial Agent Altering PD: Relevance of MIC.
(5)Lecture by –Dr. Hina Gokhale (Director,HR,DRDO,New Delhi)
Topic- Research /Innovation and Human Capital Management.
Tenth day
(1)Lecture by-Dr.P.L.Sahu (Principal Scientific Officer,IPC,Ghazibad)
Topic- Impurity Profiling and Genotoxicity.
(2)Lecture by-Shashank K. Singh (Senior Scientist,CSIR)
Topic-Cancer Drug Discovery from Natural Pdt.
(3)Valedictory Session by -T.R.Bhardwaj (Baddi University), Professor (Dr.) D. P. Pathak (Director DIPSAR)