Online Resource 2: Search Strategy

Online Resource 2: Search strategy

1. Key question: Is the relationship between magnesium levels and metabolic syndrome?
2. PICO
P / Age 18 year and older (human)
I
C / magnesium
O / metabolic syndrome, diabetes
3. Selection of keywords
PICO / Selection of Keywords
MeSH / MeSH Entry Terms / Text Word
C / "Magnesium"[Mesh] / Magnesium
O / "Metabolic Syndrome X"[Mesh] / Insulin Resistance Syndrome X
Syndrome X, Metabolic
Syndrome X, Insulin Resistance
Metabolic X Syndrome
Syndrome, Metabolic X
X Syndrome, Metabolic
Dysmetabolic Syndrome X
Syndrome X, Dysmetabolic
Reaven Syndrome X
Syndrome X, Reaven
Metabolic Cardiovascular Syndrome
Cardiovascular Syndrome, Metabolic
Cardiovascular Syndromes, Metabolic
Syndrome, Metabolic Cardiovascular / metabolic syndrome
"Diabetes Mellitus"[Mesh] / Diabetes Insipidus
Diabetic Diet
Prediabetic State
ScleredemaAdultorum
Glycosylation End Products, Advanced
Glucose Intolerance
Gastroparesis / diabetes
Restrition / Human
DB / Search / Keywords/ Search strategy / Hits / Note
PubMed / #1 / "Magnesium"[Mesh] / 61,512
#2 / "Magnesium"[TW] / 92,395
#3 / ("Magnesium"[Mesh]) OR "Magnesium"[TW] / 92,395
#4 / "Metabolic Syndrome X"[Mesh] / 19,801
#5 / "Metabolic Syndrome X"[TW] OR “Insulin Resistance Syndrome X"[TW] OR “Syndrome X, Metabolic"[TW] OR “Syndrome X, Insulin Resistance"[TW] OR “Metabolic X Syndrome"[TW] OR “Syndrome, Metabolic X"[TW] OR “X Syndrome, Metabolic"[TW] OR “Dysmetabolic Syndrome X"[TW] OR “Syndrome X, Dysmetabolic"[TW] OR “Reaven Syndrome X"[TW] OR “Syndrome X, Reaven"[TW] OR “Metabolic Cardiovascular Syndrome"[TW] OR “Cardiovascular Syndrome, Metabolic"[TW] OR “Cardiovascular Syndromes, Metabolic"[TW] OR “Syndrome, Metabolic Cardiovascular"[TW] OR “metabolic syndrome"[TW] / 34,274
#6 / "Diabetes Mellitus"[Mesh] / 317,389
#7 / "Diabetes Mellitus"[TW] OR “Diabetes Insipidus"[TW] OR “Diabetic Diet"[TW] OR “Prediabetic State"[TW] OR “ScleredemaAdultorum"[TW] OR “Glycosylation End Products, Advanced"[TW] OR “Glucose Intolerance"[TW] OR “Gastroparesis"[TW] OR “diabetes"[TW] / 440,286
#8 / ((("Metabolic Syndrome X"[Mesh]) OR (("Metabolic Syndrome X"[TW] OR “Insulin Resistance Syndrome X"[TW] OR “Syndrome X, Metabolic"[TW] OR “Syndrome X, Insulin Resistance"[TW] OR “Metabolic X Syndrome"[TW] OR “Syndrome, Metabolic X"[TW] OR “X Syndrome, Metabolic"[TW] OR “Dysmetabolic Syndrome X"[TW] OR “Syndrome X, Dysmetabolic"[TW] OR “Reaven Syndrome X"[TW] OR “Syndrome X, Reaven"[TW] OR “Metabolic Cardiovascular Syndrome"[TW] OR “Cardiovascular Syndrome, Metabolic"[TW] OR “Cardiovascular Syndromes, Metabolic"[TW] OR “Syndrome, Metabolic Cardiovascular"[TW] OR “metabolic syndrome"[TW))) OR "Diabetes Mellitus"[Mesh]) OR (("Diabetes Mellitus"[TW] OR “Diabetes Insipidus"[TW] OR “Diabetic Diet"[TW] OR “Prediabetic State"[TW] OR “ScleredemaAdultorum"[TW] OR “Glycosylation End Products, Advanced"[TW] OR “Glucose Intolerance"[TW] OR “Gastroparesis"[TW] OR “diabetes"[TW])) / 485,409
#9 / ((("Magnesium"[Mesh]) OR "Magnesium"[TW])) AND (((("Metabolic Syndrome X"[Mesh]) OR (("Metabolic Syndrome X"[TW] OR “Insulin Resistance Syndrome X"[TW] OR “Syndrome X, Metabolic"[TW] OR “Syndrome X, Insulin Resistance"[TW] OR “Metabolic X Syndrome"[TW] OR “Syndrome, Metabolic X"[TW] OR “X Syndrome, Metabolic"[TW] OR “Dysmetabolic Syndrome X"[TW] OR “Syndrome X, Dysmetabolic"[TW] OR “Reaven Syndrome X"[TW] OR “Syndrome X, Reaven"[TW] OR “Metabolic Cardiovascular Syndrome"[TW] OR “Cardiovascular Syndrome, Metabolic"[TW] OR “Cardiovascular Syndromes, Metabolic"[TW] OR “Syndrome, Metabolic Cardiovascular"[TW] OR “metabolic syndrome"[TW))) OR "Diabetes Mellitus"[Mesh]) OR (("Diabetes Mellitus"[TW] OR “Diabetes Insipidus"[TW] OR “Diabetic Diet"[TW] OR “Prediabetic State"[TW] OR “ScleredemaAdultorum"[TW] OR “Glycosylation End Products, Advanced"[TW] OR “Glucose Intolerance"[TW] OR “Gastroparesis"[TW] OR “diabetes"[TW]))) / 1,554 / #3 AND #8
#10 / ("animals"[MeSH] NOT "Humans"[MeSH]) / 3,958,860
#11 / ((((("Magnesium"[Mesh]) OR "Magnesium"[TW])) AND (((("Metabolic Syndrome X"[Mesh]) OR (("Metabolic Syndrome X"[TW] OR “Insulin Resistance Syndrome X"[TW] OR “Syndrome X, Metabolic"[TW] OR “Syndrome X, Insulin Resistance"[TW] OR “Metabolic X Syndrome"[TW] OR “Syndrome, Metabolic X"[TW] OR “X Syndrome, Metabolic"[TW] OR “Dysmetabolic Syndrome X"[TW] OR “Syndrome X, Dysmetabolic"[TW] OR “Reaven Syndrome X"[TW] OR “Syndrome X, Reaven"[TW] OR “Metabolic Cardiovascular Syndrome"[TW] OR “Cardiovascular Syndrome, Metabolic"[TW] OR “Cardiovascular Syndromes, Metabolic"[TW] OR “Syndrome, Metabolic Cardiovascular"[TW] OR “metabolic syndrome"[TW))) OR "Diabetes Mellitus"[Mesh]) OR (("Diabetes Mellitus"[TW] OR “Diabetes Insipidus"[TW] OR “Diabetic Diet"[TW] OR “Prediabetic State"[TW] OR “ScleredemaAdultorum"[TW] OR “Glycosylation End Products, Advanced"[TW] OR “Glucose Intolerance"[TW] OR “Gastroparesis"[TW] OR “diabetes"[TW]))))) NOT ((("animals"[MeSH] NOT "Humans"[MeSH]))) / 1,303 / #9 NOT #10
excluding study of Animal
>Import to EndNote
#12 / #11 Filters: Adult: 19+ years / 635
DB / Search / Keywords/ Search strategy / Hits / Notes
PubMed / #1 / "Magnesium"[Mesh] / 61,516
#2 / "Magnesium"[TW] / 92,411
#3 / ("Magnesium"[Mesh]) OR "Magnesium"[TW] / 92,411
#4 / "Metabolic Syndrome X"[Mesh] / 19,821
#5 / "Metabolic Syndrome X"[TW] OR “Insulin Resistance Syndrome X"[TW] OR “Syndrome X, Metabolic"[TW] OR “Syndrome X, Insulin Resistance"[TW] OR “Metabolic X Syndrome"[TW] OR “Syndrome, Metabolic X"[TW] OR “X Syndrome, Metabolic"[TW] OR “Dysmetabolic Syndrome X"[TW] OR “Syndrome X, Dysmetabolic"[TW] OR “Reaven Syndrome X"[TW] OR “Syndrome X, Reaven"[TW] OR “Metabolic Cardiovascular Syndrome"[TW] OR “Cardiovascular Syndrome, Metabolic"[TW] OR “Cardiovascular Syndromes, Metabolic"[TW] OR “Syndrome, Metabolic Cardiovascular"[TW] OR “metabolic syndrome"[TW] / 34,303
#6 / "Diabetes Mellitus"[Mesh] / 317,461
#7 / "Diabetes Mellitus"[TW] OR “Diabetes Insipidus"[TW] OR “Diabetic Diet"[TW] OR “Prediabetic State"[TW] OR “ScleredemaAdultorum"[TW] OR “Glycosylation End Products, Advanced"[TW] OR “Glucose Intolerance"[TW] OR “Gastroparesis"[TW] OR “diabetes"[TW] / 440,502
#8 / ((("Metabolic Syndrome X"[Mesh]) OR (("Metabolic Syndrome X"[TW] OR “Insulin Resistance Syndrome X"[TW] OR “Syndrome X, Metabolic"[TW] OR “Syndrome X, Insulin Resistance"[TW] OR “Metabolic X Syndrome"[TW] OR “Syndrome, Metabolic X"[TW] OR “X Syndrome, Metabolic"[TW] OR “Dysmetabolic Syndrome X"[TW] OR “Syndrome X, Dysmetabolic"[TW] OR “Reaven Syndrome X"[TW] OR “Syndrome X, Reaven"[TW] OR “Metabolic Cardiovascular Syndrome"[TW] OR “Cardiovascular Syndrome, Metabolic"[TW] OR “Cardiovascular Syndromes, Metabolic"[TW] OR “Syndrome, Metabolic Cardiovascular"[TW] OR “metabolic syndrome"[TW))) OR "Diabetes Mellitus"[Mesh]) OR (("Diabetes Mellitus"[TW] OR “Diabetes Insipidus"[TW] OR “Diabetic Diet"[TW] OR “Prediabetic State"[TW] OR “ScleredemaAdultorum"[TW] OR “Glycosylation End Products, Advanced"[TW] OR “Glucose Intolerance"[TW] OR “Gastroparesis"[TW] OR “diabetes"[TW])) / 485,649
#9 / ((("Magnesium"[Mesh]) OR "Magnesium"[TW])) AND (((("Metabolic Syndrome X"[Mesh]) OR (("Metabolic Syndrome X"[TW] OR “Insulin Resistance Syndrome X"[TW] OR “Syndrome X, Metabolic"[TW] OR “Syndrome X, Insulin Resistance"[TW] OR “Metabolic X Syndrome"[TW] OR “Syndrome, Metabolic X"[TW] OR “X Syndrome, Metabolic"[TW] OR “Dysmetabolic Syndrome X"[TW] OR “Syndrome X, Dysmetabolic"[TW] OR “Reaven Syndrome X"[TW] OR “Syndrome X, Reaven"[TW] OR “Metabolic Cardiovascular Syndrome"[TW] OR “Cardiovascular Syndrome, Metabolic"[TW] OR “Cardiovascular Syndromes, Metabolic"[TW] OR “Syndrome, Metabolic Cardiovascular"[TW] OR “metabolic syndrome"[TW))) OR "Diabetes Mellitus"[Mesh]) OR (("Diabetes Mellitus"[TW] OR “Diabetes Insipidus"[TW] OR “Diabetic Diet"[TW] OR “Prediabetic State"[TW] OR “ScleredemaAdultorum"[TW] OR “Glycosylation End Products, Advanced"[TW] OR “Glucose Intolerance"[TW] OR “Gastroparesis"[TW] OR “diabetes"[TW]))) / 1,555 / #3 AND #8
#10 / ("animals"[MeSH] NOT "Humans"[MeSH]) / 3,958,860
#11 / ((((("Magnesium"[Mesh]) OR "Magnesium"[TW])) AND (((("Metabolic Syndrome X"[Mesh]) OR (("Metabolic Syndrome X"[TW] OR “Insulin Resistance Syndrome X"[TW] OR “Syndrome X, Metabolic"[TW] OR “Syndrome X, Insulin Resistance"[TW] OR “Metabolic X Syndrome"[TW] OR “Syndrome, Metabolic X"[TW] OR “X Syndrome, Metabolic"[TW] OR “Dysmetabolic Syndrome X"[TW] OR “Syndrome X, Dysmetabolic"[TW] OR “Reaven Syndrome X"[TW] OR “Syndrome X, Reaven"[TW] OR “Metabolic Cardiovascular Syndrome"[TW] OR “Cardiovascular Syndrome, Metabolic"[TW] OR “Cardiovascular Syndromes, Metabolic"[TW] OR “Syndrome, Metabolic Cardiovascular"[TW] OR “metabolic syndrome"[TW))) OR "Diabetes Mellitus"[Mesh]) OR (("Diabetes Mellitus"[TW] OR “Diabetes Insipidus"[TW] OR “Diabetic Diet"[TW] OR “Prediabetic State"[TW] OR “ScleredemaAdultorum"[TW] OR “Glycosylation End Products, Advanced"[TW] OR “Glucose Intolerance"[TW] OR “Gastroparesis"[TW] OR “diabetes"[TW]))))) NOT ((("animals"[MeSH] NOT "Humans"[MeSH]))) / 1,305 / #9 NOT #10
excluding of Animal study
import to EndNote
DB / Search / Keywords/ Search strategy / Hits / Notes
Cochrane / #1 / MeSH descriptor: [Magnesium] explode all trees / 1,051
#2 / "Magnesium":ti,ab,kw / 3,866
#3 / #1 or #2 / 3,866
#4 / MeSH descriptor: [Metabolic Syndrome X] explode all trees / 918
#5 / "Metabolic Syndrome X":ti,ab,kw or "Insulin Resistance Syndrome X":ti,ab,kw or "Syndrome X, Metabolic":ti,ab,kw or "Syndrome X, Insulin Resistance":ti,ab,kw or "Metabolic X Syndrome":ti,ab,kw or "Syndrome, Metabolic X":ti,ab,kw or "X Syndrome, Metabolic":ti,ab,kw or "Dysmetabolic Syndrome X":ti,ab,kw or "Syndrome X, Dysmetabolic":ti,ab,kw or "Reaven Syndrome X":ti,ab,kw or "Syndrome X, Reaven":ti,ab,kw or "Metabolic Cardiovascular Syndrome":ti,ab,kw or "Cardiovascular Syndrome, Metabolic":ti,ab,kw or "Cardiovascular Syndromes, Metabolic":ti,ab,kw or "Syndrome, Metabolic Cardiovascular":ti,ab,kw or "metabolic syndrome":ti,ab,kw / 2,011
#6 / MeSH descriptor: [Diabetes Mellitus] explode all trees / 16,572
#7 / "Diabetes Mellitus":ti,ab,kw or "Diabetes Insipidus":ti,ab,kw or "Diabetic Diet":ti,ab,kw or "Prediabetic State":ti,ab,kw or "ScleredemaAdultorum":ti,ab,kw or "Glycosylation End Products, Advanced":ti,ab,kw or "Glucose Intolerance":ti,ab,kw or "Gastroparesis":ti,ab,kw or "diabetes":ti,ab,kw / 27,531
#8 / #4 or #5 or #6 or #7 / 30,226
#9 / #3 and #8 / 125 / > Import to EndNote
DB / Search / Keywords/ Search strategy / Hits / Note
EMBASE / #1 / magnesium'/exp OR magnesium / 133,054
#2 / metabolic syndrome x'/exp OR 'metabolic syndrome x' / 50,317
#3 / metabolic syndrome x'/exp OR 'metabolic syndrome x' OR 'insulin resistance syndrome x' OR 'syndrome x, metabolic'/exp OR 'syndrome x, metabolic' OR 'syndrome x, insulin resistance' OR 'metabolic x syndrome' OR 'syndrome, metabolic x' OR 'x syndrome, metabolic' OR 'dysmetabolic syndrome x' OR 'syndrome x, dysmetabolic' OR 'reaven syndrome x' OR 'syndrome x, reaven' OR 'metabolic cardiovascular syndrome' OR 'cardiovascular syndrome, metabolic' OR 'cardiovascular syndromes, metabolic' OR 'syndrome, metabolic cardiovascular' OR 'metabolic syndrome'/exp OR 'metabolic syndrome' / 61,052
#4 / diabetes mellitus'/exp OR 'diabetes mellitus' / 661,410
#5 / diabetes mellitus'/exp OR 'diabetes mellitus' OR 'diabetes insipidus'/exp OR 'diabetes insipidus' OR 'diabetic diet'/exp OR 'diabetic diet' OR 'prediabetic state'/exp OR 'prediabetic state' OR 'scleredemaadultorum'/exp OR 'scleredemaadultorum' OR 'glycosylation end products, advanced'/exp OR 'glycosylation end products, advanced' OR 'glucose intolerance'/exp OR 'glucose intolerance' OR 'gastroparesis'/exp OR 'gastroparesis' OR 'diabetes'/exp OR 'diabetes' / 789,480
#6 / #2 OR #3 OR #4 OR #5 / 815,971
#7 / #1 AND #6 / 3,687
#8 / animals'/exp OR 'animals' NOT ('humans'/exp OR 'humans') / 4,384,042
#9 / #7 NOT #8 / 3,267 / excluding study of Animal
#10 / #9 AND [embase]/lim NOT [medline]/lim / 1,157 / Only EMBASE search
> import to EndNote
DB / PubMed / Cochrane / Embase / Sum / Duplicates / Final number
Hits / 1,305 / 125 / 1,157 / 2,587 / 65 / 2,522