Program Director/Principal Investigator (Last, First, Middle)

Program Director/Principal Investigator (Last, First, Middle):

BIOGRAPHICAL SKETCH

Provide the following information for the Senior/key personnel and other significant contributors in the order listed on Form Page 2.
Follow this format for each person. DO NOT EXCEED FOUR PAGES.
NAME
Thèrése Bocklage, M.D. / POSITION TITLE
Professor, UNM School of Medicine Department of Pathology, Director of UNM Human Tissue Repository
eRA COMMONS USER NAME (credential, e.g., agency login)
EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable.)
INSTITUTION AND LOCATION / DEGREE
(if applicable) / MM/YY / FIELD OF STUDY
Boston College / B.S. / 05/82 / Biology, A&S Honors Program
Medical College of Toledo / M.D. / 05/86 / Medical Degree
University of Vermont Medical College / 6/91 / AP/CP Residency
University of New Mexico School of Medicine / 7/92 / Surgical Pathology Fellowship
Baylor College of Medicine, Houston Texas / 7/95 / Cytopathology Fellowship

A. Personal Statement

I am a practicing clinician educator with collaboration in translational research utilizing my skills as a surgical pathologist and cytopathologist. The majority of my time is spent in direct patient care in surgical pathology and cytopathology. I also participate actively in the education of pathology residents and the surgical pathology and cytopathology fellows at our instititution. I direct the UNM Human Tissue Repository, and in that role, I work with the NCI OBBR in optimizing human biospecimen quality through a competitive contract awarded August, 2010. My clinical-research interests comprise tumors of the soft tissues and bone, breast tumors, and tumors of the head and neck.

B. Positions and Honors

EMPLOYMENT:

2007-present: Professor, Department of Pathology, University of New Mexico School of Medicine

2001-2007: Associate Professor, Department of Pathology, University of New Mexico School of Medicine

1995-2001: Assistant Professor, Department of Pathology, University of New Mexico School of Medicine

1992-1994: Instructor I-III, Department of Pathology, University of New Mexico School of Medicine

POSITIONS:

2008-Current: Director, University of New Mexico SOM Human Tissue Repository

2007-Current: Director, UNM SOM Department of Pathology Cytopathology Fellowship

2006-Current: Institutional Pathology, Children’s Oncology Group (COG)

1997-2006: Director, UNM Dept. of Pathology Residency Program

MEMBERSHIPS:

Fellow, College of American Pathologists (CAP)

Fellow, American Society of Clinical Pathologists (ASCP)

Member, USCAP Soft Tissue Tumor Society

HONORS:

2004: UNM School of Medicine Excellence in Teaching Award at the Resident Education Level for Academic Year 2003-2004

2003: Dean’s Award of Distinction for Outstanding Faculty Performance, UNM School of Medicine Academic Year 2001-2002

2001: Dean’s Award of Distinction for Outstanding Faculty Performance, UNM School of Medicine Academic Year 1999-2000

2000: Dean’s Award of Distinction for Outstanding Faculty Performance, UNM, School of Medicine Academic Year 1998-1999

1999: UNM School of Medicine Excellence in Teaching Award at the Resident Education Level for Academic Year 1997-1998

1998: Dean’s Award of Distinction for Outstanding Faculty Performance, UNM, School of Medicine, Academic Year 1996-1997

C. Selected Peer-reviewed Publications (selected from 40 peer reviewed publications)

1. Sayar H, Bunning JT, Bocklage TJ, Lee S-J, Libby E, Rabinowitz, I. Tumor MET expression may not predict the risk of venous thromboembolism in cancer patients. Oncology Research 19:93-97, 2010.

2. Krier K, Henderson JB, Bocklage T, Rajput A. Duodenal pseudomelanosis. Surgery 2010 Oct 21 [Epub ahead of print]

3. Smith M, Hagerty KA, Skipper B, Bocklage T. Chronic endometritis: combined histopathologic and clinical review of cases from 2002-2007. Int J Gynecol Pathol 2010 29(1): 44-50. Review.

4. Arias-Pulido H, Smith HO, Joste NE, Bocklage T, Qualls CR, Chavez A, Prossnitz ER, Verschraegen CF. Estrogen and progesterone receptor status and outcome in epithelial ovarian cancers and low malignant potential tumors. Gynecologic Oncology 2009 114(3):480-5.

5. Mourant JR, Powers TM, Bocklage TJ, Greene HM, Dorin MH, Waxman AG, Zsemlye MM, Smith HO. In vivo light scattering for the detection of cancerous and precancerous lesions of the cervix. Appl Opt. 2009 Apr 1;48(10):D26-35.

6. Davis LM, Harris C, Tang L, Doherty P, Hraber P, Sakai Y, Bocklage T, Doeden K, Hall B, Alsobrook J, Rabinowitz I, Williams TM, Hozier J. Amplification patterns of three genomic regions predict distant recurrence in breast carcinoma. J Molecular Diagnostics 2007 9(3):327-36.

7. Belinsky SA, Grimes MJ, Casas E, Stidley CA, Franklin WA, Bocklage TJ, Johnson DH, Schiller JH. Predicting gene promoter methylation in non-small-cell lung cancer by evaluating sputum and serum. British J Cancer 2007 96(8):1278-83.

8. Mourant JR, Bocklage TJ, Powers TM, Greene HM, Bullock KL, Marr-Lyon LR, Dorin MH, Waxman AG, Zsemlye MM, Smith HO. In vivo light scattering measurements for detection of precancerous conditions of the cervix. Gynecologic Oncology 2007 105(2): 439-45.

9. Grimes JS, Bocklage TJ, Pitcher JD. Collagen and biphasic calcium phosphate bone graft in large osseous defects. Orthopedics 2006 Feb:29(2):145-8.

10. Rosen SA, Bocklage T, Clericuzio CL. Mucocutaneous squamous papilloma with reactive lymphoid hyperplasia in two patients with focal dermal hypoplasia. Pediatric Developmental Pathology 2005 8(2): 250-2.

11. Divine KK, Pulling LC, Marron-Terada PG, Liechty KC, Kang T, Schwartz AG, Bocklage TJ, Coons TA, Gilliland FD, Belinsky SA. Multiplicity of abnormal promoter methylation in lung adenocarcinomas from smokers and never smokers. International Journal Cancer 2005 114(3): 400-5.

12. Petitt M, Doeden K, Harris A, Bocklage T. Cutaneous extrarenal rhabdoid tumor with myogenic differentiation. J Cutaneous Pathology 2005 32(10): 690-5.

13. Belinsky SA, Klinge DM, Dekker JD, Smith MW, Bocklage TJ, Gilliland FD, Crowell RE, Karp DD, Stidley CA, Picchi MA. Gene promoter methylation in plasma and sputum increases with lung cancer risk. Clinical Cancer Research 2005 11(18): 6505-11.

14. Warren JL, Weaver DL, Bocklage T, Key CR, Platz CE, Cronin KA, Ballard C, Barbash R, Willey SC, Harlan LC. The frequency of ipsilateral second tumors after breast-conserving surgery for DCIS: a population based analysis. Cancer 2005 104(9):1840-8.

15. Rund CR, Bocklage T. Pathologic quiz case: lytic femoral lesion and renal cysts in a 66-year-old man. Occult follicular carcinoma of the thyroid. Arch Pathol Lab Med. 2004 128(3):359-60.

16. Pulling LC, Divine KK, Klinge DM, Gilliland FD, Kang T, Schwartz AG, Bocklage TJ, Belinsky SA. Promoter hypermethylation of the O6-methylguanine-DNA methyltransferase gene: more common in lung adenocarcinomas from never-smokers than smokers and associated with tumor progression. Cancer Research 2003 15(16):4842-8.

17. Bocklage T, Leslie K, Yousem S, Colby T. Extracutaneous angiosarcomas metastatic to the lungs: clinical and pathologic features of twenty-one cases. Mod Pathol 2001 14(12):1216-25.

D. Research Support

1) Project Title: S09-148 Biospecimen Contributing Institutions for Research Studies in Cancer Tissue Pre-Analytical Variables.

Role: principal investigator- Direct the project at UNM contributing ~2000 highly annotated human blood and tissue specimen sets to the national NCI biobank.

Principal investigator: Thèrése Bocklage, M.D.

Percent effort: 15%

Funding Organization: National Cancer Institute (NCI)

Starting and stopping dates: August 2010- July 2015

Amount awarded for the period listed (direct and indirect costs): $3,829,000

2) Project Title: P30CA11800-06

Role: collaborator

Principal investigator: Cheryl L. Willman, M.D.

Percent effort: 15%

Funding Organization: National Institutes of Health (NIH)

Starting and stopping dates: October 2010-September 2015

Amount awarded for the period listed (direct and indirect costs): ~$11,000,000

3) Project Title: Clinical Translational Science Center for the University of New Mexico School of Medicine

Role: collaborator

Principal investigator: Richard Larson, M.D., Ph.D.

Percent effort: 5%

Funding Organization: National Institutes of Health (NIH)

Starting and stopping dates: January 2011- December 2016

Amount awarded for the period listed (direct and indirect costs): ~$15,000,000

4) Project Title: P50 Subaward: Understanding and Preventing Breast Cancer Disparities in Latinas

Role: collaborator

Principal investigator: Linda Cook, Ph.D.

Percent Effort: 5% year one, 3% years 2-5

Funding Organization: National Institutes of Health (NIH)

Starting and stopping dates: December, 2010-November 2005.

Amount awarded for the period listed (direct and indirect costs): ~ $3,000,000

PHS 398/2590 (Rev. 06/09) 1 | Page