Table S2. Technical analysis of ESTs in F. graminearum and F. culmorum found in MIPS FGDB.

GenBank

accession

FG ORF DNA1 Sequence coordinates2 number Comments3

No ORF hit (FG) 1.16 – (92005 – 92182) DY763143 (Fs14662935), 3E-16

FG00551 (FG) 1.22 – (86678 – 86908) DY763076

FG00775-ext (FG) 1.35 – (223361 – 223535) DY763077

FG12075 (FC) 1.35 – (260938 – 261323) DY763078

FG01004-ext (FC) 1.48 – (21581 – 21885) DY588253

FG01047(FG) 1.52 – (30977 – 31195) DY763079 In conflict with MIPS

intron annotation

FG01092-ext (FG) 1.53 – (47975 – 48206) DY763133 A possible extension. PA

FG01101 (FC) 1.54 – (6400 – 6649) ES316460

No ORF hit (FG) 1.60 – (24498 – 24582) DY763134 Gibberella zeae cDNA clone (CV827945). 1E-09

FG01226-ext (FC) 1.61 – (18996 – 19306) DY763080

No ORF hit (FC) 1.62 – (47958 – 48093) DY763131 14-3-3 family protein,

(GzCon[0751]), 7E-70

FG01351 (FC) 1.66 – (53251 – 53472) DY763081

FG01417 (FC) 1.71 – (12091 – 12332) / DY588265 Intron from 12333 - 12381

1.71 – (12382 – 12517) Confirming MIPS intron

annotation. PA

FG01584-ext (FG) 1.79 – (95806 – 96152) DY588287 PA

FG04336 (FG) 1.87 – (12828 – 12885) DY763082

No ORF hit (FG) 1.87 – (71585 – 71786) DY588295 (Gz47835827), E-115

FG01749 (FG) 1.92 – (36388 – 36725) DY588296

FG01826 (FG) 1.94 – (4344 – 4497) / DY588297 Intron from 4498 - 4544

1.94 – (4545 – 4637) Confirming MIPS intron

annotation

FG01837-ext (FC) 1.94 – (29558 – 29645) DY763122 PA

No ORF hit (FC) 1.103 – (102642 – 102722) DY763123 Unknown

FG01959 (FG) 1.104 – (101858 – 102037) DY763084

FG02022-ext (FG) 1.110 – (20581 – 20792) DY763085

FG02119 (FG) 1.111 – (117609 – 117667) DY763086

FG02247-ext (FG) 1.114 – (69924 – 70222) DY763087 PA

FG02409-ext (FG) 1.122 – (12807 – 12985) DY763088

FG02582 (FG) 1.128 – (71175 – 71523) DY763089 In conflict with MIPS

intron annotation. PA

FG02666 (FG) 1.132 – (171547 – 171791) DY588298

FG02667-ext (FC) 1.132 – (172760 – 172954) DY588299

FG02668 (FC) 1.132 – (178017 – 178280) DY588254

FG02692-ext (FC) 1.133 – (30645 – 30741) DY763090

FG02705(FG) 1.135 – (13506 – 13702) DY763091

FG02795-ext (FC) 1.141 – (9215 – 9518) DY763092 PA

FGD142-220-ext(FG) 1.142 – (50491 – 50675) DY763093 PA

FG02894 (FC) 1.142 – (148358 – 148736) DY588255

FG03081 (FC) 1.147 – (96409 – 96771) DY588256

FG03086 (FG) 1.147 – (108665 – 108706) DY588258

FG03184 (FG) 1.148 – (246279 – 246541) DY588258

FG03190-ext (FG) 1.148 – (263999 – 264260) / DY588259 Intron from 264261 -

1.148 – (264312 – 264482) 264311. In conflict with

MIPS intron annotation

FG03199-ext (FG) 1.149 – (17323 – 17443) DY588260 PA

FG03650(FC) 1.160 – (230723 – 231113) DY763094

FG03735 (FG) 1.162 – (71423 – 71543) DY588261 In conflict with MIPS

intron annotation. PA

FG03738-ext (FG) 1.162 – (82539 – 82941) DY588262 PA

FG03831 (FG) 1.166 – (39278 – 39485) DY763095

No ORF hit (FG) 1.167 – (33252 – 33549) DY763142 Related to hypothetical

protein FG04501

(XP_384677), 4E-24. PA

FG03995(FG) 1.168 – (322348 – 322582) DY763096

FG04230-ext (FG) 1.185 – (148526 – 148743) DY763097 In conflict with MIPS

intron annotation.

FG04405-ext (FC) 1.190 – (85129 – 85362) DY763098 PA

No ORF hit (FG) 1.192 – (15825 – 15989) DY588276 Unknown

FG04512 (FG) 1.192 – (206995 – 207241) DY763099

FG04924-ext (FC) 1.199 – (89707 – 89789) DY763100 In conflict with MIPS

intron annotation. PA

FG05061-ext (FC) 1.203 – (59778 – 60280) DY588264 Alternative splicing

1.203 – (59778 – 60025) / DY588263 Intron from 60026 - 60074

1.203 – (60075 – 60280)

FG05095 (FG) 1.205 – (19354 – 19618) DY588266

No ORF hit (FG) 1.212 – (127510 – 127859) DY763138 Unknown

FG05290 (FG) 1.212 – (229180 – 229349) DY763101

No ORF hit (FC) 1.213 – (18683 – 18975) DY588267 Mitochondrial outer

membrane protein involved in membrane fission (GzCon[0585]), 9E-83

FG05422 (FC) 1.224 – (2300 – 2488) DY763102

No ORF hit (FC) 1.227 – (28138 – 28381) DY763124 Unknown. PA

No ORF hit (FG) 1.229 – (24151 – 24346) DY763136 (GzCon[2149]), 3E-90.PA

FG05636 (FC) 1.231 – (72451 – 72684) DY763103

No ORF hit (FC) 1.231 – (120756 – 120835) DY763125 Unknown

FG05821-ext (FG) 1.233 – (91186 – 91418) DY588269 PA

FG05890-ext (FC) 1.233 – (298463 – 298678) DY763104

FG05928-ext (FG) 1.237 – (87542 – 87860) / DY588270 Intron from 87861-87922.

1.237 – (87923 – 88035) Confirming MIPS intron

annotation

FG05929-ext (FG) 1.237 – (89064 – 89165) DY588271 A possible extension. PA

FG06070 (FC) 1.241 – (42142 – 42174) / DY588272 Intron from 42175-42238.

1.241 – (42239 – 42275) In conflict with MIPS

intron annotation

No ORF hit (FC) 1.246 – (75513 – 75883) DY763130 Unknown. PA

No ORF hit (FG) 1.247 – (55637 – 55816) DY763135 Unknown. PA

FG06231 (FC) 1.248 – (9943 – 10118) / DY763105 Intron from 10119-10169.

1.248 – (10170 – 10189) Confirming MIPS intron

annotation.

FG06416-ext (FG) 1.258 – (101655 – 101712) EB077975 A possible extension

FG06583-ext (FG) 1.259 – (452114 – 452292) DY763146 A possible extension. PA

No ORF hit (FG) 1.266 – (156750 – 156928) DY588273 Unknown. PA

No ORF hit (FC) 1.270 – (15885 – 15954) DY763128 Gibberella zeae cDNA (CD456267). 6E-129.

FG06931 (FG) 1.285 – (43456 – 43510) / DY763107 Intron from 43511-43566.

1.285 – (43567 – 43641) Confirming MIPS intron

annotation

FG07075-ext (FG) 1.297 – (2138 – 2273) / DY763108 Genome reorganization,

1.297 – (15849 – 15936) very long (~ 13476 bp)

gap. PA

FG07076-ext (FG) 1.297 – (20066 – 20180) DY588275 PA

FG07104 (FG) 1.298 – (82046 – 82401) DY588277

FG07177-ext (FC) 1.302 – (8994 – 9198) / DY763083 Introns from 9199 - 9204

1.302 – (9205 – 9221) / and 9222 - 9227. In 1.302 – (9228 – 9353) conflict with MIPS intron

annotation

FG07442 (FG) 1.310 – (66965 – 67302) DY588278 In conflict with MIPS

intron annotation

No ORF hit (FC) 1.310 – (195402 – 195635) DY588279 Unknown

FG07551 (FG) 1.314 – (43061 – 43320) DY763109 In conflict with MIPS

intron annotation

FG07821(FG) 1.320 – (145377 – 145438) DY763140 In conflict with MIPS

intron annotation. PA

FGD321-640 (FC) 1.321 – (169058 – 169423) DY763121 In conflict with MIPS

intron annotation

FG08245-ext (FG) 1.329 – (199666 – 199898) DY588280 PA

Fg4A76 (FC) 1.335 – (88255 – 88499) DY588281 PA

FG08540(FC) 1.345 – (10215 – 10510) DY763110

FG08597-ext (FG) 1.348 – (59658 – 59896) DY763111 PA

No ORF hit (FG) 1.349 – (78544 – 78640) DY763140 (Gz47836378), 2E-49. PA

FG08710-ext (FC) 1.353 – (20581 – 20921) DY588282 A possible extension

FG08811-ext (FC) 1.355 – (133410 – 133589) DY588283 EF1A

FG08844(FC) 1.358 – (7238 – 7493) DY763106

FG08847-ext (FC) 1.358 – (19738 – 19804) / DY763112 Introns from 19805-19853

1.358 – (19854 – 19913) / and 19914 - 19964. Both

1.358 – (19965 – 20150) confirming and in conflict

with MIPS intron

annotation

No ORF hit (FG) 1.361 – (13097 – 13267) DY588284 Gibberella moniliformis cDNA (DR616112).5E-33

FG09103 (FG) 1.370 – (170788 – 170921) / DY588286 Intron from 170922 - 1.370 – (170974 – 171025) 170973. Confirming MIPS

intron annotation

FG09355-ext (FG) 1.383 – (26422 – 26465) DY588288

No ORF hit (FC) 1.402 – (21363 – 21594) DY763126 Unknown

FG09840-ext (FG) 1.406 – (218821 – 219145) DY588289 In conflict with MIPS

intron annotation. PA

FG09866(FG) 1.409 – (23623 – 23749) / DY763113 Intron from 23750-23802.

1.409 – (23803 – 23877) Confirming MIPS intron

annotation

FG09913 (FG) 1.411 – (108392 – 108833) DY588290 In conflict with MIPS

intron annotation

FG09976 (FC) 1.415 – (17825 – 18151) DY588291

FG10084 (FG) 1.417 – (211586 – 211792) DY588292

FGD417-780 (FG) 1.417 – (219399 – 219586) DY588293 In conflict with MIPS

intron annotation

FG10292(FC) 1.425 – (114347 – 114408) DY763114

FG10313-ext (FC) 1.425 – (159147 – 159490) DY763115 MGV1. PA

No ORF hit (FG) 1.430 – (8124 – 8301) DY763145 Unknown

FG10387-ext (FG) 1.433 – (73302 – 73612) DY588274 PA

FG10423-ext (FC) 1.434 – (21062 – 21284) DY763116 PA

FG10589-ext (FG) 1.444 – (18983 – 19215) DY588294

FGD447-70 (FC) 1.447 – (22370 – 22720) DY763117

FG10758-ext (FC) 1.447 – (133745 – 133953) DY763127

FG10997-ext (FG) 1.458 – (97723 – 97788) DY763118 PA

FG11012-ext (FG) 1.458 – (141228 – 141409) / DY763119 Intron from 141400 -

1.458 – (141461 – 141493) 141460. Confirming MIPS

intron annotation. PA

No ORF hit (FG) 1.458 – (207151 – 207330) DY763137 Unknown

No ORF hit (FC) 1.458 – (72543 – 72634) DY763129 Unknown

FG11190-ext (FG) 1.460 – (103341 – 103444) / DY763120 Intron from 103445 -

1.460 – (103495 – 103652) 103494. Confirming MIPS

intron annotation

FG11310-ext (FG) 1.464 – (119003 – 119209) DY588268

1The ESTs are marked with the gene name according to the annotated MIPS FGDB if they are situated in the coordinates of the gene sequence, or with an additional -ext, e.g. FG00775-ext, if they are putative extensions of the predicted genes. The “No ORF hits” are completely outside the MIPS gene annotations. FG = F. graminearum, FC = F. culmorum. 2All sequence coordinates are given on the plus strain. 3The “No ORF hits” are described with Blast results (Cogeme, NCBI), with Cogeme Unisequence ID or GenBank accession number for the best match in parentheses. E values greater than E-05 were listed as “Unknown”. The commented polyadenylation tails (PA) begin at the end of the GenBank sequence.

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