This bulletin covers aspects of gynaecological cancers and should be of interest to multidisciplinary teams working in this area.

Sections can include:

·  Combined Modality Therapies

·  Drug Therapy

·  Pathology, Staging, Polymorphisms & Biomarkers

·  Prognosis, Survival & Risk Factors

·  Radiotherapy & Imaging

·  Supportive Care & Symptom Management

·  Surgery

Many of the following articles are available online via the NHS Scotland Knowledge Network. Please use the links where provided and your ATHENS password. A complete list of available online journals and registration for ATHENS can be found at www.knowledge.scot.nhs.uk/

If the article you require is not available via the NHS Scotland Knowledge Network and you would like to request a print copy, please submit your request online at www.quest.scot.nhs.uk

This bulletin contains a selection of material gathered from a search of the evidence base, and is not intended to be comprehensive. Professional judgment should be exercised when appraising the material. The Library takes no responsibility for the wording, content and accuracy of the information supplied, which has been extracted in good faith from reputable sources. NHSGGC is not responsible for the content of external internet sites.

Compiled by:

Kirsty Coltart

Subject Librarian

Beatson West of Scotland Cancer Centre

0141 301 7285,

General

Duska LR, Mueller J, Lothamer H, et al. (2015). Lean methodology improves efficiency in outpatient academic Gynecologic Oncology clinics. Gynecologic oncology 138,3:707-711.

Fung-Kee-Fung M, Kennedy EB, Biagi J, et al. (2015). The optimal organization of gynecologic oncology services: a systematic review. Current Oncology 22,4:e282-93.

Lheureux S, Karakasis K, Kohn EC, et al. (2015). Ovarian cancer treatment: The end of empiricism?. Cancer 121,18:3203-3211.

Liang MI, ElNaggar AC, Nekkanti S, et al. (2015). Setting the bar: compliance with ovarian cancer quality indicators at a National Cancer Institute-designated Comprehensive Cancer Center. Gynecologic oncology 138,3:689-693.

Combined Modality Therapies

Chantalat E, Vidal F, Leguevaque P, et al. (2015). Cervical cancer with paraaortic involvement: do patients truly benefit from tailored chemoradiation therapy? A retrospective study on 8 French centers. European Journal of Obstetrics, Gynecology, & Reproductive Biology 193,118-122.

Das S, Subhashini J, Rami Reddy JK, et al. (2015). Low-dose fractionated radiation and chemotherapy prior to definitive chemoradiation in locally advanced carcinoma of the uterine cervix: Results of a prospective phase II clinical trial. Gynecologic oncology 138,2:292-298.

Favero G, Macerox N, Pfiffer T, et al. (2015). Oncologic Concerns regarding Laparoscopic Cytoreductive Surgery in Patients with Advanced Ovarian Cancer Submitted to Neoadjuvant Chemotherapy. Oncology 89,3:159-166.

Kehoe S, Hook J, Nankivell M, et al. (2015). Primary chemotherapy versus primary surgery for newly diagnosed advanced ovarian cancer (CHORUS): an open-label, randomised, controlled, non-inferiority trial. Lancet 386,9990:249-257.

Meyer LA, Bohlke K, Powell MA, et al. (2015). Postoperative Radiation Therapy for Endometrial Cancer: American Society of Clinical Oncology Clinical Practice Guideline Endorsement of the American Society for Radiation Oncology Evidence-Based Guideline. Journal of Clinical Oncology 33,26:2908-2913.

Drug & Targeted Therapy

Chapman JA, Costantino JP, Dong B, et al. (2015). Octreotide LAR and tamoxifen versus tamoxifen in phase III randomize early breast cancer trials: NCIC CTG MA.14 and NSABP B-29. Breast Cancer Research & Treatment 153,2:353-360.

Kumar L, Pramanik R, Kumar S, et al. (2015). Neoadjuvant chemotherapy in gynaecological cancers - Implications for staging. Best Practice & Research in Clinical Obstetrics & Gynaecology 29,6:790-801.

Moore KN, Sill MW, Tenney ME, et al. (2015). A phase II trial of trebananib (AMG 386; IND#111071), a selective angiopoietin 1/2 neutralizing peptibody, in patients with persistent/recurrent carcinoma of the endometrium: An NRG/Gynecologic Oncology Group trial. Gynecologic oncology 138,3:513-518.

Oza AM, Cook AD, Pfisterer J, et al. (2015). Standard chemotherapy with or without bevacizumab for women with newly diagnosed ovarian cancer (ICON7): overall survival results of a phase 3 randomised trial. Lancet Oncology 16,8:928-936.

Roviello F, Roviello G, Petrioli R, et al. (2015). Hyperthermic intraperitoneal chemotherapy for the treatment of ovarian cancer: A brief overview of recent results. Critical Reviews in Oncology-Hematology 95,3:297-305.

Sayal K, Gounaris I, Basu B, et al. (2015). Epirubicin, Cisplatin, and Capecitabine for Primary Platinum-Resistant or Platinum-Refractory Epithelial Ovarian Cancer: Results of a Retrospective, Single-Institution Study. International Journal of Gynecological Cancer 25,6:977-984.

Vergote I, Debruyne P, Kridelka F, et al. (2015). Phase II study of weekly paclitaxel/carboplatin in combination with prophylactic G-CSF in the treatment of gynecologic cancers: A study in 108 patients by the Belgian Gynaecological Oncology Group. Gynecologic oncology 138,2:278-284.

Wiggans AJ, Cass GK, Bryant A, et al. (2015). Poly(ADP-ribose) polymerase (PARP) inhibitors for the treatment of ovarian cancer. Cochrane Database of Systematic Reviews 5,007929.

Woopen H, Richter R, Chekerov R, et al. (2015). The influence of comorbidity and comedication on grade III/IV toxicity and prior discontinuation of chemotherapy in recurrent ovarian cancer patients: An individual participant data meta-analysis of the North-Eastern German Society of Gynecological Oncology (NOGGO). Gynecologic oncology 138,3:735-740.

Pathology, Staging, Polymorphisms & Biomarkers

Borley J and Brown R. (2015). Epigenetic mechanisms and therapeutic targets of chemotherapy resistance in epithelial ovarian cancer. Annals of Medicine 47,5:359-369.

Green RW, Engblom S, Baldetorp B, et al. (2015). Cell proliferation, measured as flow cytometric S-phase fraction, is a strong prognostic indicator in FIGO stage I endometrioid endometrial carcinoma: a population-based study. Acta Obstetricia et Gynecologica Scandinavica 94,10:1064-1073.

HIS (2015). IMTO 005/2015 Innovative Medical Technology Overview: Dysis

Leong HS, Galletta L, Etemadmoghadam D, et al. (2015). Efficient molecular subtype classification of high-grade serous ovarian cancer. Journal of Pathology 236,3:272-277.

Nezhat FR, Apostol R, Nezhat C, et al. (2015). New insights in the pathophysiology of ovarian cancer and implications for screening and prevention. American Journal of Obstetrics & Gynecology 213,3:262-267.

Nikolaidis C, Nena E, Panagopoulou M, et al. (2015). PAX1 methylation as an auxiliary biomarker for cervical cancer screening: A meta-analysis. Cancer Epidemiology 39,5:682-686.

O'Mara TA, Glubb DM, Painter JN, et al. (2015). Comprehensive genetic assessment of the ESR1 locus identifies a risk region for endometrial cancer. Endocrine-related cancer 22,5:851-861.

Oswald AJ and Gourley C. (2015). Low-grade epithelial ovarian cancer: a number of distinct clinical entities?. Current opinion in oncology 27,5:412-419.

Prat J and FIGO Committee on Gynecologic Oncology. (2015). Abridged republication of FIGO's staging classification for cancer of the ovary, fallopian tube, and peritoneum. Cancer 121,19:3452-3454.

Prat, J. (2015). Ovarian, fallopian tube and peritoneal cancer staging: Rationale and explanation of new FIGO staging 2013. Best Practice & Research in Clinical Obstetrics & Gynaecology 29,6:858-869.

Ramus SJ, Song H, Dicks E, et al. (2015). Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer. Journal of the National Cancer Institute 107,11:

Worley MJ Jr, Liu S, Hua Y, et al. (2015). Molecular changes in endometriosis-associated ovarian clear cell carcinoma. European journal of cancer 51,13:1831-1842.

Zighelboim I, Ali S, Lankes HA, et al. (2015). Assessing the prognostic role of ATR mutation in endometrioid endometrial cancer: An NRG Oncology/Gynecologic Oncology Group study. Gynecologic oncology 138,3:614-619.

Prognosis, Survival & Risk Factors

Suidan RS, Leitao MM Jr, Zivanovic O, et al. (2015). Predictive value of the Age-Adjusted Charlson Comorbidity Index on perioperative complications and survival in patients undergoing primary debulking surgery for advanced epithelial ovarian cancer. Gynecologic oncology 138,2:246-251.

Zola P, Macchi C, Cibula D, et al. (2015). Follow-up in Gynecological Malignancies: A State of Art. International Journal of Gynecological Cancer 25,7:1151-1164.

Radiotherapy & Imaging

Duncan P, Mason TM and Thirlwell S. (2015). Radiation via Intracavitary-Interstitial Pelvic Implants for Gynecological Cancers: Clinical Nurse Specialists Affecting Change. Clinical Nurse Specialist 29,5:290-294.

Klapdor R, Langer F, Gratz KF, et al. (2015). SPECT/CT for SLN dissection in vulvar cancer: Improved SLN detection and dissection by preoperative three-dimensional anatomical localisation. Gynecologic oncology 138,3:590-596.

Ly D, Soisson PA, Dodson MK, et al. (2015). Adjuvant radiation therapy is associated with improved pelvic control and overall survival in FIGO IB endometrial carcinoma with high grade histology. Gynecologic oncology 138,3:526-531.

Ma X, Zhao Y, Zhang B, et al. (2015). Contrast-enhanced ultrasound for differential diagnosis of malignant and benign ovarian tumors: systematic review and meta-analysis. Ultrasound in Obstetrics & Gynecology 46,3:277-283.

Mesko S, Swamy U, Park SJ, et al. (2015). Early clinical outcomes of ultrasound-guided CT-planned high-dose-rate interstitial brachytherapy for primary locally advanced cervical cancer. Brachytherapy 14,5:626-632.

Patel N, Hegarty SE, Cantrell LA, et al. (2015). Evaluation of brachytherapy and external beam radiation therapy for early stage, node-negative uterine carcinosarcoma. Brachytherapy 14,5:606-612.

Schwarz JK, Beriwal S, Esthappan J, et al. (2015). Consensus statement for brachytherapy for the treatment of medically inoperable endometrial cancer. Brachytherapy 14,5:587-599.

Signorelli M, Crivellaro C, Buda A, et al. (2015). Staging of High-Risk Endometrial Cancer With PET/CT and Sentinel Lymph Node Mapping. Clinical nuclear medicine 40,10:780-785.

Yu C, Zhu W, Ji Y, et al. (2015). A comparative study of intensity-modulated radiotherapy and standard radiation field with concurrent chemotherapy for local advanced cervical cancer. European journal of gynaecological oncology 36,3:278-282.

Supportive Care & Symptom Management

Fastrez M, Houba C, Vandromme J, et al. (2015). Fertility-sparing management of gynecological cancers. Maturitas 82,2:141-145.

Li X, Li J and Wu X. (2015). Incidence, risk factors and treatment of cervical stenosis after radical trachelectomy: A systematic review. European journal of cancer 51,13:1751-1759.

Liem X, Saad F and Delouya G. (2015). A Practical Approach to the Management of Radiation-Induced Hemorrhagic Cystitis. Drugs 75,13:1471-1482.

Linnet Olesen M, Hansson H, Ottesen B, et al. (2015). The psychosocial needs of gynaecological cancer survivors: A framework for the development of a complex intervention. European Journal of Oncology Nursing 19,4:349-358.

Maheu C, Lebel S, Tomei C, et al. (2015). Breast and ovarian cancer survivors' experience of participating in a cognitive-existential group intervention addressing fear of cancer recurrence. European Journal of Oncology Nursing 19,4:433-440.

O'Connor M, Waller J, Gallagher P, et al. (2015). Understanding Women's Differing Experiences of Distress after Colposcopy: A Qualitative Interview Study. Womens Health Issues 25,5:528-534.

Watanabe Nemoto M, Nozaki-Taguchi N, Togasaki G, et al. (2015). New approach to relieving pain and distress during high-dose-rate intracavitary irradiation for cervical cancer. Brachytherapy 14,5:642-647.

Surgery

Basaran D, Dusek L, Majek O, et al. (2015). Oncological Outcomes of Nerve-Sparing Radical Hysterectomy for Cervical Cancer: A Systematic Review. Annals of Surgical Oncology 22,9:3033-3040.

Bradley MS and Visco AG. (2015). Role of salpingectomy at the time of urogynecologic surgery. Current opinion in obstetrics & gynecology 27,5:385-389.

Cormier B, Rozenholc AT, Gotlieb W, et al. (2015). Sentinel lymph node procedure in endometrial cancer: A systematic review and proposal for standardization of future research. Gynecologic oncology 138,2:478-485.

Corrado G, Cutillo G, Pomati G, et al. (2015). Surgical and oncological outcome of robotic surgery compared to laparoscopic and abdominal surgery in the management of endometrial cancer. European Journal of Surgical Oncology 41,8:1074-1081.

Slomovitz BM, Coleman RL, Oonk MH, et al. (2015). Update on sentinel lymph node biopsy for early-stage vulvar cancer. Gynecologic oncology 138,2:472-477.

Tse KY and Ngan HY. (2015). The role of laparoscopy in staging of different gynaecological cancers. Best Practice & Research in Clinical Obstetrics & Gynaecology 29,6:884-895.

Please note that the journal articles you are accessing are subject to the terms and conditions imposed by the publisher, so there will be a limit on the number of articles an individual may download or print from a single issue of a journal. You can consult your local NHSGGC library with any queries.

If you have any questions regarding this or any other library services please contact Library staff – contact details are at the beginning of the bulletin. Sources used for this bulletin: OVID databases, SIGN, NICE, Healthcare Improvement Scotland

Gynaecologic Oncology, October 2015

Kirsty Coltart, Subject Librarian, NHSGGC Library Network