eTable 2. Adulthood lifetime physical activity and breast cancer risk, by tumour characteristics: ER, PR receptor status, and histological type of breast cancer and type of the activity in a case-control study in Poland
(n. of cases)Average MET hrs/week of lifetime$ / ER - positive
(1074)
OR* (95% CI) / ER - negative
(563)
OR* (95% CI) / PR - positive
(902)
OR* (95% CI) / PR - negative
(728)
OR* (95% CI) / Ductal NOS
(1142)
OR* (95% CI) / Lobular
(315)
OR* (95% CI)
Recreational activity
< 39.1
39.1 – <52.8
52.8 – <70.1
≥70.1
P trend / 1.00
0.76 (0.61-0.94)
0.85 (0.69-1.05)
0.78 (0.63-0.97)
0.067 / 1.00
0.80 (0.61-1.04)
0.84 (0.64-1.09)
0.83 (0.63-1.09)
0.227 / 1.00
0.74 (0.59-0.92)
0.81 (0.65-1.00)
0.71 (0.56-0.90)
0.010 / 1.00
0.82 (0.64-1.04)
0.90 (0.71-1.15)
0.90 (0.70-1.15)
0.545 / 1.00
0.81 (0.66-0.99)
0.85 (0.70-1.05)
0.76 (0.61-0.93)
0.021 / 1.00
0.82 (0.59-1.15)
0.78 (0.55-1.10)
0.86 (0.61-1.21)
0.338
P-heterogeneity / 0.575 / 0.087 / 0.746
Recreational activity moderate or vigorous
None
>0 -<3.7
3.7-12.4
>12.4
P trend / 1.00
0.90 (0.72-1.12)
0.91 (0.73-1.13)
0.76 (0.60-0.95)
0.026 / 1.00
0.93 (0.72-1.21)
0.76 (0.58-1.00)
0.79 (0.60-1.04)
0.047 / 1.00
0.83 (0.66-1.04)
0.85 (0.68-1.06)
0.69 (0.54-0.88)
0.005 / 1.00
1.02 (0.80-1.31)
0.86 (0.67-1.11)
0.85 (0.66-1.10)
0.126 / 1.00
0.96 (0.78-1.18)
0.92 (0.74-1.13)
0.71 (0.57-0.89)
0.004 / 1.00
0.91 (0.65-1.27)
0.73 (0.51-1.04)
0.76 (0.53-1.08)
0.073
P-heterogeneity / 0.918 / 0.294 / 0.955
Household activity
<29.8
29.8– < 46.5
46.5 – <69.6
≥ 69.6
P trend / 1.00
0.67 (0.54-0.84)
0.72 (0.57-0.91)
0.84 (0.66-1.06)
0.223 / 1.00
1.04 (0.79-1.37)
0.80 (0.60-1.08)
0.88 (0.65-1.20)
0.207 / 1.00
0.73 (0.58-0.92)
0.70 (0.55-0.90)
0.85 (0.66-1.09)
0.221 / 1.00
0.87 (0.68-1.11)
0.80 (0.61-1.04)
0.85 (0.65-1.11)
0.221 / 1.00
0.82 (0.66-1.02)
0.77 (0.61-0.96)
0.90 (0.72-1.13)
0.370 / 1.00
0.57 (0.40-0.81)
0.77 (0.55-1.10)
0.68 (0.47-0.99)
0.159
P-heterogeneity / 0.780 / 0.888 / 0.583
Outdoor activity
None
>0 - < 3.8
3.8 - <13.2
≥ 13.2
P trend / 1.00
0.80 (0.65-0.98)
0.81 (0.65-1.00)
0.83 (0.67-1.03)
0.016 / 1.00
1.05 (0.82-1.36)
1.08 (0.84-1.39)
0.77 (0.57-1.02)
0.200 / 1.00
0.84 (0.67-1.04)
0.85 (0.68-1.06)
0.89 (0.71-1.12)
0.154 / 1.00
0.93 (0.74-1.18)
0.96 (0.76-1.22)
0.72 (0.56-0.94)
0.037 / 1.00
0.83 (0.68-1.02)
1.04 (0.86-1.27)
0.85 (0.68-1.05)
0.316 / 1.00
0.89 (0.65-1.24)
0.69 (0.48-0.99)
0.90 (0.64-1.27)
0.198
P-heterogeneity / 0.690 / 0.580 / 0.520
Occupational
<14.3
14.3-38.5
>38.5-73.3
>73.3
P trend / 1.00
1.13 (0.92-1.39)
1.02 (0.83-1.26)
0.81 (0.64-1.03)
0.081 / 1.00
1.21 (0.93-1.57)
1.06 (0.80-1.39)
1.01 (0.76-1.34)
0.818 / 1.00
1.03 (0.83-1.28)
1.02 (0.81-1.27)
0.86 (0.67-1.09)
0.265 / 1.00
1.36 (1.07-1.72)
1.07 (0.84-1.37)
0.93 (0.71-1.21)
0.298 / 1.00
1.21 (0.99-1.48)
0.89 (0.72-1.10)
0.87 (0.69-1.08)
0.035 / 1.00
1.23 (0.88-1.71)
1.14 (0.82-1.60)
0.89 (0.61-1.32)
0.621
P-heterogeneity / 0.176 / 0.865 / 0.403
*- adjusted for age, study site, education, BMI, age at menarche, menopausal status, age at menopause (in post menopausal), number of full term births, age at first full-term birth, breastfeeding, family history of breast cancer and previous screening mammography
*1- adjusted additionally for adulthood total lifetime household activity and total occupational physical activity
*2- adjusted additionally for adulthood total lifetime recreational and total occupational physical activity
*3- adjusted additionally for adulthood total lifetime recreational and household activity physical activity
$ - the categories of physical activity were determined using distribution among controls
1