Understanding Neuropsychiatric Lyme Disease

Understanding Neuropsychiatric Lyme Disease:

Clinical Implications for Mental Health Practitioners

Julie A. States, Ph.D.

REFERENCES

Bateman, A., Singh, A., Kral, T., & Solomon, S. The Immune-Hypothalamic-Pituitary-Adrenal Axis. Endocrine Reviews, 10(1), 92-112.

Bratton R., Whiteside J., Hovan M., Engle R., Edwards F., (2008). Diagnosis and treatment of Lyme disease. Mayo Clinic Proceedings, 83 (5)566–71.

Burrascano, J. (2008). Advanced topics in lyme disease: Diagnostic hints and treatment guidelines for lyme and other tick borne illnesses. ILADS.

Cameron, D., Johnson, L., Maloney, E. (2014). Evidence assessments and guideline recommendations in Lyme disease: the clinical management of known tick bites, erythema migrans rashes and persistent disease. Expert Review of Anti-infective Therapy,12(9), 1103-1135.

Cairns V, Godwin J. (2005). Post-Lyme borreliosis syndrome: a meta-analysis of reported symptoms. International Journal of Epidemiology, 34(6):1340-1345.

Castro, C., & Gourley, M. (2010). Diagnostic Testing and Interpretation of Tests for Autoimmunity. Journal of Allergy Clinical Immunology, 125(2), S238–S247.

Center for Disease Control. https://www.cdc.gov/lyme/index.html

Fallon B., & Nields J.(1994). Lyme disease: a neuropsychiatric illness. American Journal of Psychiatry, 151(11), 1571-1583.

Fallon, BA. (2012) Challenges in the Care of the Patient with Neuropsychiatric Lyme Disease. Presentation at the New Jersey Psychiatric Association Annual Conference: Challenges to Cure and Care. Iselin, NJ.

Fallon B, Kochevar J, Gaito A, & Nields J. (1998). The underdiagnosis of neuropsychiatric Lyme disease in children and adults. Psychiatric Clinics of North America, 21, 693–703.

Fallon B., Nields, J., Burrascano,J., Liegner, K., DelBene, D., & Liebowitz, M. (1993). The

neuropsychiatric manifestations of Lyme borreliosis. Psychiatry Quarterly, 63(1), 95-11.

Fallon B., Keilp J., Corbera K, Keptova, E., Britton, C., Dwyer, E., Slavov, I., Ceng, J., Dobkin, M., Nelson, D., & Sackeim, H. (2008). A randomized, placebo-controlled trial of repeated IV antibiotic therapy for Lyme encephalopathy. Neurology,70(13), 992-1003.

Fond, G. (2014). Inflammation in psychiatric disorders. European Psychiatry, 29(8), 551-552. https://doi.org/10.1016/j.eurpsy.2014.09.347

Greenberg, R. (2016) Tick-borne invections an dpediatric bipolar disorder. Neurology, psychiatry and brain research 22, 1-25.

Hájek T1, Pasková B, Janovská D, Bahbouh R, Hájek P, Libiger J, & Höschl C. (2002). Higher prevalence of antibodies to Borrelia burgdorferi in psychiatric patients than in healthy subjects. American Journal of Psychiatry, 159(2), 297-301.

Halperin, J. (1997). Neuroborreliosis: Central nervous system involvement. Seminars in Neurology, 17(1), 19-24.

Holmes, C., Cunningham, C, Zotova, E., Woolfird, J., Dean, C., Kerr, S., Culliford, Dlk & Perry, V. (2009). Systematic inflammation and progression of dementia in Alzhemiers Disease. Neurology,73(10), 768-774.

International Lyme and Associated Disease Society. ILADS.org

Infectious Disease Society of America. IDSociety.org

Klempner,M., Hu. L., Evans, J., Schmid, C., Johnson, G., Trevino, R., Norton, D., Levy, L., Wall, D., Mcall, J., Kosinski, M., & Weinstein, A. (2001). Two controlled trials of antibiotic treatment in patientsw with persistent symptoms and a history of Lyme Disease. New England Journal of Medicine, 345, 85-92.

Logigian, E., Kaplan, R., & Steere,C. (1990) Chronic neurologic manifestations of Lyme disease. New England Journal Medicine, 323(21), 1438-1444.

Marke, J. (2016). Tick-borne disease, lyme, and psychiatric illness. Lecture to AmericanPsychiatric Association NY Branch, Lenox Hill Hospital. New York, NY. Retrieved from https://www.youtube.com/watch?v=82I9Z9NOU9g

McGreer, P., 7 McGreer, E. (1995). The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases. Brain Research Reviews, 21(2), 195-218.

Pollina, D., Sliwinski, Squires, N., & Krupp, L.(1999). Cognitive processing speed in Lyme Disease. Neuropsychiatry, Neuropsychology, and Behavioral Neurology, 12(1), 72-78.

Rawls, W. (2017). Unlocking lyme: Myths truths and practical solutions for chronic lyme disease. FirstDoNoHarm Publishing, Cary, NC.

Sherr, V. (2000). Panic Attacks May Reveal Previously Unsuspected Chronic Disseminated Lyme Disease.Journal of Psychiatric Practice, 6, 352-356.

Singh, G., Girschick, H. (2004). Lyme borreliosis: From infection to autoimmunity. Clinical Microbiology Infection, 10(7), 598-614.

Spencer RL, Hutchison KE (1999). "Alcohol, aging, and the stress response". Alcohol Research & Health, 23 (4), 272–83.

Tager, F., Fallon, B., Kelip, J., Rissenberg, M., Jones, C., Liebowitz, M. (2001). A controlled study of cognitive deficits in children with chronic Lyme disease. Journal of Neuropsychiatry Clinical Neuroscience, 13, 500-507.

Wormser. G., Nadelman, R., & Dattwyler, R. (2000). Practice guidelines for the treatment of Lyme disease. The Infectious Diseases Society of America. Clinical Infectious Disease, 31 (Suppl 1), 1-14.

Lyme Resources/Websites

American Lyme Disease Association www.aldf.com

Lyme Disease.Org https://www.lymedisease.org/

Global Lyme Alliance

https://globallymealliance.org/

Infectious Disease Society of America http://www. IDSociety.org

International Lyme and Associated Disease Society

www.ilads.org

Lyme Disease Association https//www.lymediseaseassociation.org

Lyme Disease Network

www.lymenet.org

Psychiatric Lyme Brochure http://www.ilads.org/lyme/lyme-brochure-psych-2014.pdf

PA Lyme Resource Network

Palyme.org