LICAGE 2010

23-24 SEPTEMBER

OPERA PRIMAZIALE, PISA, ITALY

PERIOPERATIVE CARE IN LIVER TRANSPLANTATION:

UPDATE AND DEBATE

LICAGE Organising Committee Co-Chairs

Gianni Biancofiore, Pisa

John Klinck, Cambridge

Italian Organising Committee

Franco Filipponi, Professor and Head of Liver Transplantation, University School of Medicine, Pisa

Francesco Giunta, Professor and Head of Anaesthesia and Critical Care,University School of Medicine, Pisa

Giorgio Della Rocca, Professor and Head of Anaesthesia and Critical Care,University School of Medicine, Udine

Alberto Pasetto, Professor and Head of Anaesthesia and Critical Care,University School of Medicine, Modena

Stefano Faenza, Professor and Head of Anaesthesia and Critical Care for Liver Transplantation,University School of Medicine, Bologna

Andrea De Gasperi, Head of Anaesthesia and Critical Care, Ospedale Niguarda, Milano

Invited Faculty / Scientific Advisory Committee

Philip Bayly, Newcastle

James Bennett, Birmingham

Christophe Camus, Rennes

James Findlay, Rochester

Ari Ercole, Cambridge

Luciano Gattinoni, Milan

Davide Ghinolfi, Pisa

Klaus Gorlinger, Essen

Paolo Grossi, Varese

Olaf Guckelberger, Berlin

Kerry Gunn, Auckland

Can Ince, Rotterdam

Claus-Georg Krenn, Vienna

Alistair Lee, Edinburgh

Susan Mallett, London

Susan Mandell, Denver

Marco Marietta, Modena

Pilar Morales, Valencia

Claus Niemann, San Francisco

Mike Ramsay, Dallas

Marco Ranieri, Torino

Gemma Rodriguez, Valencia

Franco Ruberto, Rome

Fuat Saner, Essen

Marco Senzolo, Padua

Randolph Steadman, Los Angeles

Armando Tripodi, Milan

Gebhard Wagener, New York

Ann Walia, Nashville

Yatin Young, Auckland

Gamal Fouad S Zaki, Cairo

PROGRAMME

THURSDAY 23 SEPTEMBER

08:15 Welcome G. Biancofiore

08:20 – 10:30 Cardiovascular update Chairs: P Bayly, A De Gasperi

  • Cirrhotic cardiomyopathy and dysautonomia

Susan Mandell, Denver

  • Cardiovascular events and outcomes

Olaf Guckelberger, Berlin

  • Controversies in preoperative evaluation: testingand selection

James Findlay, Rochester

  • Management of ischemic and valvular disease at UCLA

Randolph Steadman, Los Angeles

  • Monitoring: TEE,PAC, new modalities

Giorgio Della Rocca, Udine

10:30-11:00 Coffee Break

11:00 – 12:15 Respiratory update Chairs: G Della Rocca, L Gattinoni

  • Evaluating the potential recipient: the pulmonologist’s perspective

Pilar Morales, Valencia

  • Hepatopulmonary syndrome: pathophysiology, diagnosis, outcomes

Susan Mandell, Denver

  • Post-transplant respiratory complications

Marco Ranieri, Torino

12:15 – 12:45 Penelope Kaisserli Memorial Lecture: Introduction: G Biancofiore

Acute lung injury: diagnosis and management

Luciano Gattinoni, Milan

12:45-13:45Lunch

13:45 – 15:30 Topics in Surgery, Hepatology and Infectious Disease Chairs: R Steadman, G Rodriguez

  • Liver transplantation for alcoholic liver disease: selection and outcomes

Marco Senzolo, Padua

  • Liver implantation: techniques and challenges

Davide Ghinolfi, Pisa

  • Arterial hypoperfusion in the transplanted liver

Olaf Guckelberger, Berlin

  • Early bacterial infections

Fuat Saner, Essen

  • Fungal infections in liver recipients

Paolo Grossi, Varese

15:30-16:00 Coffee Break

16:00 – 17:40 Perioperative fluids and transfusion

Chairs: J Klinck, C-G Krenn

  • Volume resuscitation in cirrhosis: do different solutions make a difference?

Luciano Gattinoni, Milan

  • Transfusion and the microcirculation

Can Ince, Rotterdam

  • Vasoconstrictors during liver transplantation: why, when and which?

Gebhard Wagener, New York

  • Analgesia, fluids and outcomes in liver resection

Yatin Young, Auckland

  • Massive transfusion: what’s new?

Kerry Gunn, Auckland

18:00 – 18:30 LICAGE Business Meeting

20:00 – 23:00 CONGRESS DINNER

FRIDAY 24 SEPTEMBER

08:15 – 10:15 Coagulation updateChairs: M Ramsay, K Gunn

  • Coagulation in end-stage liver disease: pathophysiology and monitoring

Armando Tripodi, Milan

  • Factor concentrates: why should we use them in liver transplantation?

Klaus Gorlinger, Essen

  • Plasma for coagulopathy: FFP vs SD-treated human plasma solution

Marco Marietta, Modena

  • Operating room monitoring and management

Susan Mallett, London

  • Hypercoagulation

Michael Ramsay, Dallas

10:15 - 10.45 Coffee Break

10.45 – 12:15 Basic Science and Physiology Chairs: C Niemann, J Findlay

  • Measuring the microcirculation

Can Ince, Rotterdam

  • Physics of arterial pressure monitoring and effects of vasopressors

Ari Ercole, Cambridge

  • Perioperative renal injury: novel markers

Gebhard Wagener, New York

  • Monitoring function in the transplanted liver

Claus-Georg Krenn, Vienna

12.15-13.15 Lunch

13:15 – 15:30 Special topics Chairs: G Wagener,S Mandell

  • MARS dialysis in acute liver failure

Christophe Camus, Rennes

  • Extracorporeal clearance of Lipid A: a novel therapy in sepsis

Franco Ruberto, Rome

  • Hypoadrenalism in liver recipients

Stefano Faenza, Bologna

  • Paediatric update

James Bennett, Birmingham

  • Starting a liver transplant anesthesia service in a developing country

Gamal Fouad S Zaki, Cairo

  • Data collection and quality improvementin liver transplantation

Ann Walia, Nashville

15:30-16:00Coffee Break

16.00 - 17.30 Interactive cases Chairs: P Bayly, R Steadman

Cases of special interest or educational value, presented in stages with key pauses before diagnostic or therapeutic decisions. Panel and audience input is invited (what would you do next?), as directed by the session chairs.

Erythropoietic Protoporphyria and acute liver failure

Alistair Lee, Edinburgh

Primary non-function: is there a role for hepatectomy?

Harendra Arora, Chapel Hill

Fulminant Wilson’s and Tetralogy of Fallot

Andreu Cueva Suller, Valencia

Liver resection in a high risk patient

Sundar Reddy, Iowa City

17:30 Closing remarks

President Secretary/Treasurer Scientific/Education Committee Chair

Dr Phil Bayly Prof Claus-Georg Krenn Dr Claus Niemann

Department of Anaesthesia Department of Anaesthesiology Department of Anesthesia and

FreemanHospital and General Intensive Care Perioperative Care, Department of

Newcastle MedicalUniversity Surgery, Division of Transplantation

UK Vienna, Austria University of California

San Francisco, USA