Supplement table 1. Association between PARP polymorphisms and the risk of ACPA positive and negative RA

Gene / rs number / Frequency / Codominant / Dominant / Recessive / Number / HWE
ACPA (+) / ACPA (-) / OR(95%CI) / P / Pcorr / OR(95%CI) / P / Pcorr / OR(95%CI) / P / Pcorr / ACPA (+) / ACPA (-) / ACPA (+) / ACPA (-)
PARP-1 / rs59672299 / 0.304 / 0.316 / 0.93(0.69-1.27) / 0.65 / NS / 1.02(0.68-1.53) / 0.92 / NS / 0.68(0.36-1.29) / 0.24 / NS / 627 / 117 / 0.587 / 0.326
rs1341336 / 0.218 / 0.218 / 1.04(0.74-1.47) / 0.81 / NS / 0.95(0.63-1.43) / 0.80 / NS / 2.11(0.63-7.08) / 0.23 / NS / 633 / 117 / 0.655 / 0.165
rs2271344 / 0.158 / 0.132 / 1.23(0.81-1.86) / 0.33 / NS / 1.31(0.82-2.09) / 0.25 / NS / 0.94(0.26-3.36) / 0.92 / NS / 628 / 117 / 0.855 / 0.446
rs1805413 / 0.102 / 0.082 / 1.30(0.78-2.17) / 0.32 / NS / 1.24(0.73-2.13) / 0.43 / NS / . / . / . / 619 / 116 / 0.535 / 0.337
rs1136410 / 0.471 / 0.446 / 1.09(0.82-1.46) / 0.55 / NS / 0.86(0.54-1.36) / 0.51 / NS / 1.64(0.94-2.87) / 0.08 / NS / 629 / 112 / 0.498 / 0.042
rs2271347 / 0.070 / 0.059 / 1.21(0.67-2.20) / 0.52 / NS / 1.18(0.64-2.17) / 0.60 / NS / . / . / . / 633 / 118 / 0.971 / 0.493
ht1 / 0.361 / 0.360 / 0.98(0.72-1.33) / 0.88 / NS / 0.82(0.54-1.24) / 0.35 / NS / 1.54(0.74-3.19) / 0.25 / NS / 631 / 118 / 0.166 / 0.012
ht2 / 0.145 / 0.153 / 0.99(0.66-1.48) / 0.95 / NS / 0.94(0.60-1.45) / 0.77 / NS / 2.31(0.29-18.64) / 0.43 / NS / 631 / 118 / 0.294 / 0.214
ht3 / 0.157 / 0.131 / 1.23(0.81-1.86) / 0.33 / NS / 1.32(0.83-2.10) / 0.24 / NS / 0.85(0.24-3.06) / 0.80 / NS / 631 / 118 / 0.645 / 0.437
ht4 / 0.139 / 0.191 / 0.68(0.47-0.97) / 0.03 / NS / 0.75(0.48-1.15) / 0.19 / NS / 0.24(0.10-0.63) / 0.003 / 0.02 / 631 / 118 / 0.928 / 0.027
ht5 / 0.100 / 0.076 / 1.38(0.82-2.33) / 0.23 / NS / 1.33(0.77-2.30) / 0.31 / NS / . / . / . / 631 / 118 / 0.568 / 0.370
ht6 / 0.069 / 0.059 / 1.20(0.67-2.18) / 0.54 / NS / 1.17(0.63-2.15) / 0.62 / NS / . / . / . / 631 / 118 / 0.999 / 0.493

HWE: Hardy-Weinberg equilibrium