CURRICULUM VITAE
Date and place of birth: 04.07.1972, Aalst
Nationality: Belgium
Languages: Dutch (First language)
English
French
Working address: University Medical Center Groningen,
Dep. of Anesthesia (EB32)
Hanzeplein 1,
Postbus 30.001
9700 RB Groningen
Netherlands
Telephone: +31 50 361 61 61
E-mail:
E-mail:
Education
College: St.-Hendrikscollege, Deinze 1990
Academic Training (University)
Medical doctor (Arts), Ghent University, Date: 1.07.1997
Post-academic education
Post-academic education, specialization, doctoral thesis,
Licenses and certificates / University / DateCertificate Electrocardiography / Ghent University / 2.07.1996
Certificate Post-academic training in
Anesthesiology / AVU (Departments of Flemish
Universities) / 1998
Certificate acute medicine: / AZ Sint-Jan Brugge
Dep. Of Emergency Medicine / 8.05.2000
Certificate Advanced Life Support Providers
Course / European Resuscitation Council,
Brussels / 19-20.03.2000
Specialist in anesthesiology and reanimation’ by
the Ministry of Social Affairs, Health and
Environment (Belgium) / 1997 - 1998: UZ Gent:
Mentor Prof. Dr. G. Rolly
1998 - 1999: AZ St.- Jan, Brugge
Stagemeester Dr. J.P. Mulier,
1999 - 2002: UZ Gent
Coordinating Mentor
Prof. Dr. E. Mortier / 1.08.2002
Specialist in anesthesiology and reanimation’ in
the Netherlands / BIG and KNMG registration,
Ministry of Health, well-being and
sports, The Netherlands / 11.05.2010
(until 2015)
Basic course Regulations and Organization for
clinical researchers (BROK) / The Dutch federation of university
hospitals, NFU / 12.07.2012
Advanced Trauma Life Support (ATLS) provider / The American College of Surgeons:
Harlem Hospital New York / 07-08/06/2013
Teach the Teacher course / The Wenckebach Institute,
Groningen, The Netherlands / 13-12-2013
European Patient Safety Course, Euroanaesthesia pre-Congress Course / European Society of
Anaesthesiologists / 27-05-2016
Doctor in Medical Sciences (PhD)
Promotor: / Prof. dr. M Struys
Universiteit: / Ghent University
Datum: / 08.11.2007
3. Professional carrier
Function or Task / Institution or Employer / From / UntilTrainee anesthesia and
reanimation / Dep. Of Anesthesia, UZ Gent
AZ St-Jan, Brugge
Dep. Of Anesthesia, UZ Gent / 1.08.1997
1.08.1998
1.08.1999 / 31.07.1998
31.07.1999
31.07.2002
Resident
Anesthesia for general,
hepatobiliary and digestive
surgery
/ University Hospital Ghent
Department of Anesthesia / 1.08.2002 / 31.12.2005
Deputy-head of clinics
Anesthesia for liver
transplantation
Anesthesia forNeurosurgery / University Hospital Ghent
Department of Anesthesia / 1.01.2006 / 31.12.2007
Head of Clinics
Anesthesia for
Neurosurgery / University Hospital Ghent
Department of Anesthesia / 1.02.2008 / 31.08.2010
Anesthesiologist / University Medical Center Groningen
Department of Anesthesia / 1.09.2010 / Current
Assistant Professor in
Anesthesia / University of Groningen (RUG) / 1.04.2012 / Current
Member of the Institutional
Medical Ethical Commission / University Medical Center Groningen / 1.02.2013 / 01.02.2016
President of the de-central Incident notification commission of the department of anesthesia / University Medical Center Groningen / 1.05.2013 / 01.09.2016
Board member / The International Society of Anesthetic
Pharmacology / 1.10.2013 / Current
Anesthesiologist (Temporary approval) / General Hospital AZ Sint-Jan Brugge
Oostende AV, Brugge, Belgium / 1.09.2016 / 29.11.2016
Anesthesiologist / General Hospital AZ Sint-Jan Brugge
Oostende AV, Brugge, Belgium / 30.11.2016 / current
4. Educative experience
Multiple ALS courses (Advanced Life Support) for ICU nurses
Multiple Lessons for the post-academic training in anesthesiology on pharmacology
Multiple lessons in “Arteveldehogeschool” (Nursing school) on Pediatric anesthesia
Multiple lessons for the junior trainees Anesthesiology (UMCG): Pharmacology in anesthesia
Multiple lectures and workshops on national and international conferences
5. Scientific CURRICULUM : (cf. addenda 1, 2 en 3)
Summaryof scientific activities throughout my academic career:
Publications in national and international scientific journals: 39
Publications in top 25% of SCI Ranking (including submitted and under revision): 34
Book chaptersin scientific review books: 4
Posters and abstracts on national and international conventions and symposia: 42
Lectures on national and international conventions and symposia: 51
Personal RG score on Research Gate: 36.13
H-Index: 17
6. Scientific Prices, Grants and Recognitions
1) Price for best publication in the category Clinical Research of the Society for Anesthesia and Resuscitation of Belgium (2006): Cerebral State Index during Propofol Anesthesia: Erik W. Jensen, Hector Litvan , Mirem Revuelta, Pere Caminal, Bernardo E. Rodriguez, Hugo Vereecke, Michel MRF Struys – 500 Euro2) Price for best publication in the category Clinical Research of the Society for Anesthesia and Resuscitation of Belgium (2012): Sevoflurane-Remifentanil Interaction: Comparison of Different Response Surface Models.: B. Heyse, J.H. Proost, P. M. Schumacher, T. W. Bouillon, H.E.M. Vereecke, D.J. Eleveld, M. Luginbuehl, M. M. R. F. Struys. -500 Euro
3) Grant of the section Pediatric Anesthesia of the Dutch Society of Anesthesiology: 2011, Development and validation of a pediatric effect-site controlled TCI model. – 400 Euro
4) Laureate (Second price out of 900 abstracts) in the “runner up competition” for best abstract 2013 at the Euroanesthesia, annual meeting 2013, Barcelona Spain: Drug interaction models are better predictors of tolerance/response to noxious stimuli compared to individual measured parameters: LN Hannivoort, JH Proost, M Luginbühl, DJ Eleveld, MMRF Struys, HEM Vereecke. - 2000 Euro
5) 2014: Non-restrictive educational Grant from NeuroWave Systems Inc., 2490 Lee Boulevard, Suite 300, Cleveland Heights, OH 44118 – 10000 Euro
6) 2015: Non-restrictive educational Grant from Medtronic Covidien Inc., Switserland – 1000 Euro
7) 2015: Non-restrictive educational Grant from Draeger Medical, Lubbeck: 3000 Euro
8) 2014-2016: Sponsor initiated study on EEG measurements during anesthesia: Research Grant from Masimo Inc: 600000 Euro
CHRONOLOGICAL SCIENTIFIC CURRICULUM
PUBLICATIONS
Books
Chapter in a book
Hugo Vereecke, Michel Struys
Depth of anaesthesia monitoring
In: The Year in Anaesthesia & Critical Care - Volume 1, Chapter 10, p. 231-249, Clinical Publishing Oxford,UK, 2005 eds. J Hunter, T Cook, HJ Prieve, M Struys
Erik Weber Jensen, Pablo Martinez, Hector Litvan, Hugo Vereecke, Bernardo Rodriguez
and Michel MRF Struys
Recent advances in composite AEP/ EEG indices for estimating hypnotic depth during general anesthesia?
In: Handbook of Neural Engineering, The Institute of Electrical and Electronics Engineers,
Wiley-IEEE Press, January 2007, Chapter 33, p. 535-553, ed. Metin Akay
ISBN 9778-0-470-05669
Hugo Vereecke, Hans Proost, Douglas Eleveld, Michel Struys:
Chapter 3: “Drug Interactions in anesthesia”
In: Clinical Pharmacology for Anesthesiology
Ed.: Ken Johnson
New York : McGraw-Hill Education Medical, [2015]
Hugo Vereecke, Martin Lüginbuhl, Klaus Oykalla:
Interactions in anesthesia
In: The Oxford Medical Handbook for Anaesthesia, 2017
Section Ed: Michel Struys
In Press
Articles
a1) articles in journals with Science Citation Index
1. Hugo E.M. Vereecke, Michel M.R.F. Struys, Eric P. Mortier
A Comparison of Bispectral Index and ARX-derived Auditory Evoked Potential Index in measuring the clinical interaction between ketamine and propofol anaesthesia.
Anaesthesia 2003, 58:957- 61
2. Michel MRF Struys, Hugo E.M. Vereecke, Annelies Moerman, Erik Weber Jensen, David Verhaeghen, Nikolaas De Neve, Frank JE Dumortier, Eric P Mortier
Ability of Bispectral Index, Autoregressive Modelling with Exogenous Input- derived Auditory Evoked Potentials and Predicted Propofol Concentrations to Measure Patient Responsiveness during Anesthesia with Propofol and Remifentanil.
Anesthesiology 2003; 99:802-12
3. ALG Vanluchene, H Vereecke, O Thas, EP Mortier, SL Shafer, MMRF Struys
Spectral entropy as an electroencephalographic measure of anesthetic drug effect. A comparison with bispectral index and processed mid-latency auditory evoked response.
Anesthesiology 2004, 101(1): 34-42
4. Anneliese T. Moerman, Michel M. R. F. Struys, Hugo E. Vereecke, Luc L. Herregods,
Martine M. De Vos and Eric P. Mortier:
Remifentanil used to supplement propofol does not improve quality of sedation during spontaneous respiration.
Journal of Clinical Anesthesia 2004, 16:237-43
5. Everaert K, Kerckhaert W, Caluwaerts H, Audenaert M, Vereecke H, De Cuypere G, Boelaert A, Van den Hombergh U, OosterlinckW A:
Prospective Randomized Trial Comparing the 1-Stage with the 2-Stage Implantation of a Pulse Generator in Patients with Pelvic Floor Dysfunction Selected for Sacral Nerve Stimulation.
European Urology 2004, 45 (5): 649-54
6. HEM Vereecke, PM Vasquez, EW Jensen, O Thas, R Vandenbroecke, EP Mortier, MMRF Struys:
New composite index based on midlatency auditory evoked potential and electroencephalographic parameters to optimize correlation with propofol effect-site concentrations: comparision with bispectral index and solitary used fast extracting auditory evoked potential index
Anesthesiology 2005, 103:500-7
7. Lebbinck H, Bouchez S, Vereecke H, Vanoverbeke H, Troisi R, Reyntjens K
Sequential off-pump coronary artery bypass and liver transplantation.
Transpl Int. 2006 May;19 (5):432-4.
8. Erik W. Jensen, Hector Litvan , Mirem Revuelta, Pere Caminal, Bernardo E. Rodriguez, Hugo Vereecke, Michel MRF Struys
Cerebral State Index during Propofol Anesthesia. A comparison with the Bispectral index and A-line ARX index.
Anesthesiology 2006, 105: 28-36
9. Hugo EM Vereecke, Ann Vanluchene, K Everaert, Eric P. Mortier, Michel MRF Struys
The effects of ketamine and rocuronium on the A-Line® auditory evoked potential index, bispectral index and spectral entropy monitor during steady state propofol and remifentanil anesthesia.
Anesthesiology 2006, 105: 1122-34
10. Mathieu Jospin, Peter Caminal, Erik W Jensen, Hector Litvan, Montserrat Vallverdù, Michel MRF Struys, Hugo EM Vereecke and Daniel T Kaplan
Detrended fluctuation analysis of EEG as a measure of depth of Anesthesia IEEE Transactions on Biomedical Engineering 2007, 54 (5):840-6
11. Martin Luginbühl, Peter M. Schumacher, Pascal Vuilleumier, Hugo Vereecke, Björn Heyse, Thomas W. Bouillon and Michel MRF Struys
Noxious Stimulation Response Index (NSRI): A novel anesthetic state index based on hypnotic-opioid interaction. Anesthesiology 2010, 112 (4): 872-80
12. Marc Coppens, Jurgen Van Limmen, Thomas Schnider, Barbara Wyler, Sjoert Bonte, Frank Dewaele, Michel MRF Struys, Hugo EM Vereecke.
Study of the time course of the clinical effect of propofol versus the time course of the predicted effect-site concentration of propofol. Performance of three pharmacokinetic-dynamic models in steady-state conditions. British Journal of Anaesthesia 2010, 104: 452-8
13. David Liley, Nicholas Sinclair, Tarmo Lipping, Bjorn Heyse, Hugo Vereecke,
Michel Struys. Propofol and remifentanil differentially modulate frontal electroencephalographic activity. Anesthesiology 2010;113(2):292-304
14. Dewaele F, Kalmar AF, Van Canneyt K, Vereecke H, Absalom A, Caemaert J, Struys MM, Van Roost D. Pressure monitoring during neuroendoscopy: new insights.
Br J Anaesth 2011;107:218-24.
15. Marc J. Coppens, Douglas J. Eleveld, Johannes H. Proost, Luc A.M. Marks, Jan F.P. Van Bocxlaer, Hugo Vereecke, Anthony R Absalom, Michel M.R.F. Struys.
The value of using population pharmacokinetic models to estimate pharmacodynamic parameters for propofol and BIS in children
Anesthesiology 2011;115:83-93.
16. MMRF Struys, M. Sahinovic, B.J. Lichtenbelt, HEM Vereecke, A.R. Absalom: Optimizing IV drug administration by applying PK/PD concepts. British Journal of Anaesthesia 2011; 107 (1): p1–10
17. B. Heyse, J.H. Proost, P. M. Schumacher, T. W. Bouillon, H.E.M. Vereecke, D.J. Eleveld, M.Luginbuehl, M. M. R. F. Struys: Sevoflurane-Remifentanil Interaction: Comparison of Different Response Surface Models: Anesthesiology 2012; 116:311-23
Accompanying editorial of Shafer, S., All models are wrong: Anesthesiology 2012;116:240-241
18. Vereecke H.E.M., Proost J.H., Heyse B., Eleveld D.J., Katoh T, Luginbuehl M., Struys M.M.R.F.: The interaction between nitrous oxide, sevoflurane and opioids: a response surface approach; Anesthesiology. 118(4):894-902, April 2013
19. F. Dewaele, C. Mabilde, B. Blanckaert, G. Meyns, J. Quintelier, C. Vandevelde, M. De Beule, H. Vereecke, A. Kalmar, JP. Kalala, E. Baert, L. Leybaert, D. Van Roost, J. Caemaert: A Novel Design For Steerable Endoscopic Instruments. Journal for surgical innovation: June 201421:303-311
20. M.M. Sahinovic, D.J. Eleveld, A. Kalmar, E.H. Heeremans, T. Desmedt, C.V. Seshagiri, A.R. Absalom, H.E.M. Vereecke, M.M.R.F.Struys: Accuracy of the Composite Variability Index as a measure of the balance between nociception and antinociception during anesthesia. Anesth Analg. 2014 Aug;119(2):288-301.
21. B. Heyse, J.H. Proost, L.N. Hannivoort, D. J. Eleveld, M. Luginbühl, M.M.R.F. Struys, H.E.M. Vereecke: Response Surface Model Approach for Continuous Measures Of Hypnotic and Analgesic Effect During Sevoflurane-Remifentanil Interaction: Quantifying The Pharmacodynamic Shift Evoked By Stimulation. Anesthesiology. 2014 Jun;120(6):1390-9
22. Mehrnaz Shoushtarian, M.M. Sahinovic, A.R. Absalom, A.F. Kalmar, H.E.M. Vereecke, David T.J. Liley, Michel MRF Struys: Comparisons of electroencephalographically derived measures of hypnosis and antinociception in response to standardized pain stimuli during target controlled propofol-remifentanil anesthesia. Anesthesia and Analgesia. 2015. 120(6): 1235-1241.
23. Laura N Hannivoort, Douglas J Eleveld, Johannes H Proost, Koen MEM Reyntjens, Anthony R Absalom, Hugo EM Vereecke, Michel MRF Struys: Development of an optimized pharmacokinetic model of dexmedetomidine using target controlled infusion in healthy volunteers. Anesthesiology. 2015; 123: 357-67.
24. Remco A. Koster, Hugo E.M. Vereecke, Ben Greijdanus, Daan J. Touw, Michel M.R.F. Struys, Jan-Willem C. Alffenaar: Analysis of remifentanil with LC-MS/MS and an extensive stability investigation in whole blood and acidified EDTA plasma. Anesthesia and Analgesia. 2015; 120 (6); 1235-41.
25. Marieke Poterman, Jaap. J. Vos, Hugo E.M. Vereecke, Michel M.R.F. Struys, Henk Vanoverschelde, Thomas W.L. Scheeren, Alain F. Kalmar. Differential effects of phenylephrine and norepinephrine on peripheral tissue oxygenation during general anesthesia. A randomized controlled trial. Eur J Anaesthesiology 2015 Aug;32(8):571-80
26. Pieter Colin, Douglas J. Eleveld, Johannes P. van den Berg, Hugo E.M. Vereecke, Michel M.R.F. Struys, Gustav Schelling, Christian C. Apfel, Cyrill Hornuss. Propofol breath monitoring as a potential tool to improve the prediction of intraoperative plasma concentrations. Clinical Pharmacokinetics, pp 1-11, First online: 29 December 2015. DOI 10.1007/s40262-015-0358-z
27. Laura N. Hannivoort, Hugo E.M. Vereecke, Johannes H. Proost, Bjorn Heyse, Douglas J. Eleveld, Thomas Bouillon, Michel M.R.F. Struys, Martin Luginbühl. Probability to Tolerate Laryngoscopy and Noxious Stimulation Response Index as General Indicators of the Anesthetic Potency of Sevoflurane, Propofol and Remifentanil. British Journal of Anaesthesia. 116(5):624-631: May 2016
28. Michel MRF Struys, Tom De Smet, John B. Glenn, Hugo E.M. Vereecke, Anthony R. Absalom, Thomas W. Schnider: The history and concepts of target controlled infusion. Anesthesia and Analgesia.2016. 122, 1, p. 56 69 p.
29. Hugo Vereecke, Douglas J Eleveld, Pieter Colin, Michel Struys: Performance of the Eleveld pharmacokinetic model to titrate propofol in the Obese Japanese patient population. Letter to the editor. Eur J Anaesthesiol. 2016 Jan;33(1):58
30. Douglas J. Eleveld, PhD, Johannes H. Proost, Hugo Vereecke, Anthony R. Absalom, Erik Olofsen, Jaap Vuijk, Michel M. R. F. Struys. An allometric model of remifentanil pharmacokinetics and pharmacodynamics. Submitted to Anesthesiology. Submitted Oct 2015.