Table 1. Overall study topics and study designs (n=3139)

n (%)
Design / No RCT / 2764 (88.1)
RCT / 375 (11.9)
Topic / Oncology / 1544 (49.2)
Voiding dysfunction / 740 (23.6)
Sexual function/infertility / 245 (7.8)
Urolithiasis/endourology / 213 (6.8)
Infection/inflammation / 120 (3.8)
Pediatric urology / 76 (2.4)
Laparoscopy/robotics / 49 (1.6)
Others / 152 (4.8)

Table 2. Analysis of RCTs

Period
1998-1999
(n=86) / Period
2008-2009
(n=288) / p value
Topic category, n (%)
Oncology
Voiding dysfunction
Other* / 47 (54)
32 (36.8)
8 (9.2) / 124 (43.1)
66 (22.9)
98 (34) / .000
Origin, n (%)
Europe
USA
Other / 77 (88.5)
8 (9.2)
2 (2.3) / 194 (67.4)
20 (6.9)
74 (25.7) / .000
Multi-institutional, n (%) / 34 (39.1) / 136 (47.2) / .181
Full lenght publication, n (%) / 8 (18.8) / 57 (39.6) / .027
Item, n (%)
1.  Title Identification
2.  Rationale
3.  Objective or hypothesis
4.  Trial design
5.  Eligibility criteria for participants and the settings
6.  Interventions
7.  Primary outcome for this report
8.  Randomisaton
9.  Blinding
10.  Number of participants randomised
11.  Recruitment Trial status
12.  Number of participants analysed
13.  For the primary outcome, a result for each group
14.  Adverse events
15.  Interpretation of the results / 42 (48.3)
74 (85.1)
71 (81.6)
70 (80.5)
58 (66.7)
67 (77)
61 (70.1)
34 (39.1)
20 (23)
57 (65.5)
23 (26.4)
60 (69.8)
67 (77)
46 (52.9)
83 (95.4) / 92 (31.9)
214 (74.3)
236 (81.9)
225 (78.1)
158 (54.9)
175 (60.8)
172 (59.7)
117 (40.6)
61 (21.2)
162 (56.3)
140 (48.6)
115 (39.9)
211 (73.3)
117 (40.6)
281 (27.6) / .005
.037
.943
.641
.051
.006
.080
.797
.720
.124
.000
.000
.484
.043
.288
Score items, n, mean (SD) / 9.5 (2.1) / 8.6 (2.0) / .000
Score ratio, %, mean (SD) / 63.8 (14.4) / 57.3 (13.4) / .000

*Infection/inflammation; Urolithiasis/endourology; Sexual function/infertility; Pediatric urology; Laparoscopy/robotics


Table 3. Analysis of non RCTs

Period
1998-1999
(n=1250) / Period
2008-2009
(n=1486) / p value
Topic category
Oncology
Voiding dysfunction
Other* / 522 (41.4)
326 (25.8)
414 (32.8) / 851 (56.7)
316 (21)
335 (22.3) / .000
Origin
Europe
USA
Other / 1067 (85.1)
60 (4.8)
127 (10.1) / 1075 (72.1)
101 (6.8)
316 (21.2) / .000
Multi-institutional, n (%) / 94 (7.4) / 537 (35.8) / .000
Full lenght publication, n (%) / 182 (14.6) / 206 (13.8) / .538
Item, n (%)
1.  Identification of study design in the title
2.  Rationale
3.  Objective or hypothesis
4.  Key elements of study design
5.  Setting, location and relevant dates
6.  Eligibility criteria
7.  Definition of outcomes
8.  Methods of assessment
9.  Statistical methods
10.  Individuals at each stage of study
11.  Characteristics of participants
12.  Follow-up time
13.  Outcome events or summary measures
14.  Other analyses done
15.  Key findings with reference to study objectives
16.  Overall interpretation / 63 (5)
1015 (80.7)
976 (77.6)
985 (78.4)
588 (46.8)
803 (63.9)
734 (58.4)
779 (62)
214 (17)
774 (61.7)
499 (39.7)
441 (35.1)
910 (72.5)
303 (24.1)
1003 (79.9)
620 (49.4) / 205 (13.7)
1227 (81.9)
1186 (79.2)
1194 (79.8)
957 (63.9)
635 (42.4)
820 ((54.8)
749 (50)
338 (22.6)
975 (65.1)
740 (49.4)
609 (40.7)
1058 (70.7)
459 (30.7)
1334 (89.1)
809 (54.4) / .000
.411
.296
.390
.000
.000
.054
.000
.000
.061
.000
.003
.304
.000
.000
.010
Score items, n, mean (SD) / 8.5 (2.4) / 8.8 (2.1) / 0.000
Score ratio, %, mean (SD) / 53.2 (15.4) / 55.4 (13.4) / 0.000

*Infection/inflammation; Urolithiasis/endourology; Sexual function/infertility; Pediatric urology; Laparoscopy/robotics

Table 4. Prediction of full publication: multivariable analysis

OR, CI 95% / P value
Time period (98-99 vs 08-09) / 0.82 (0.66 – 1.03) / .102
Topic / Oncology
Voiding dysfunction / 0.81 (0.62 – 1.06) / .134
Other* / 1.14 (0.89 – 1.46) / .275
Origin / Europe
USA / 1.03 (0.68 – 1.56) / .959
Other* / 0.96 (0.72 – 1.28) / .876
Design (No RCT vs RCT ) / 1.15 (0.85 – 1.55) / .347
Setting (Multi-institutinal vs single) / 1.82 (1.44 – 2.30) / .000
Score ratio / 1 (0.99 - 1.01) / .120

*Infection/inflammation; Urolithiasis/endourology; Sexual function/infertility; Pediatrics; Laparoscopy/robotics


Table 5. Prediction of high (>50%) score: multivariable analysis

OR, CI 95% / P value
Time period (98-99 vs 08-09) / 1.14 (0.96 – 1.35) / .130
Topic / Oncology
Voiding dysfunction / 0.98 (0.80 – 1.19) / .858
Other / 0.72 (0.60 – 0.87) / .001
Origin / Europe
USA / 0.78 (0.56 – 1.07) / .130
Other / 0.86 (0.69 – 1.07) / .181
Design (No RCT vs RCT ) / 1 (0.78 – 1.28) / .954
Setting (Multi-institutinal vs single) / 0.99 (0.82 – 1.21) / .977

*Infection/inflammation; Urolithiasis/endourology; Sexual function/infertility; Pediatrics; Laparoscopy/robotics

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