Department of Post Graduate Studies in Rasashastra

From,

Dr.Surya.S. Raj

I P.G Scholar

Department of Post Graduate Studies in Rasashastra

JSS Ayurveda Medical College

Mysore -28

To,

The Registrar

Rajiv Gandhi University of Health Sciences,Karnataka.

Bengaluru,

Through,

The Principal and Head of the Department of PG studies inRasashastra.

JSS Ayurveda Medical College.

Mysore -28

Respected Sir,

Sub: Submission of completed proforma for Registration of subject for dissertation.

I request you to kindly register the below mentioned subject against my name for the submission of dissertation to the Rajiv Gandhi University of Health Sciences,Karnataka, Bengaluru, for the partial fulfillment of M.D (Ayurveda) in Rasashastra.

Title of the dissertation:

‘‘Pharmaceutical and Analytical study on Abhraka Bhasma with special reference toAmrutheekarana and Lohitikarana’’

Here with I am enclosing completed proforma for registration of the subject for dissertation.

Thanking you

Yours faithfully,

Date:

Dr. Surya. S. Raj

Place: Mysore

Rajiv Gandhi University of Health Sciences Karnataka, Bengaluru.

ANNEXURE 2

Proforma for registration of subject for Dissertation:

1. / 1 / Name of the candidate
Address / Dr.Surya. S. Raj,B.A.M.S
I.P.G scholar.
Department of Post Graduate studies in Rasashastra.
JSS Ayurveda medical College.
Mysore -28
Residential address:
Dr.Surya.S .Raj,
Thengil House, Nedumon P.O
Ezhamkulam, Pathanamthitta, Kerala
2. / Name of the institution / JSSAyurveda Medical College
Mysore-28
3. / Course of the study & subject / Ayurveda Vachaspathi
M.D (Ayurveda) in Rasashastra
4. / Date of admission to course / 05/09/2011
5. / Title of the topic / ‘‘Pharmaceutical and Analytical study on Abhraka Bhasma with special reference toAmrutheekarana and Lohitikarana’’

6. Brief resume of intended work:

6.1 Need for the study

Abhraka is one among the six earth crust forming minerals, which is abundantly available. It has occupied a place in Maharasa. It can be used in both Lohavada and Dehavada. Krishnvajrabhraka is used in chikitsa

Bhasma is considered as most effective and important preparation in Rasashastra. Abhraka bhasma has a significant place in Ayurveda as it is used extensively and successfully in many diseases. Abhraka bhasma is vrishya, rasayana and used in jwara, premaha, swasa and kasa.

After the preparation of Abhraka Bhasma a specific process is carriedout to remove the remaining blemishes,which is called as Amrutheekarana.

Lohitikarana is a process carried out for the regeneration of lohitha varna i.e,red colour of Abhraka Bhasma after Amrutheekarana.

It is claimed that obtained Abhraka Bhasma can cure all the types of diseases.

6.2Review of literature.

In the 2nd chapter of Rasa Ratna Samucchaya, there is a reference for Shodhana of Abhraka, Dhanyabhraka Nirmana and Marana of Abhraka

Amruteekarana of Abhraka has mentioned in 4th chapter of Rasendra Chintamani

In 10th chapter of Rasatarangini, reference for Amritheekarana and Lohitikaranaof Abhraka is explained.

Previous works published

1. A study on Abhraka w.s.r Dhanyabhraka by Dr.Shreeshananda Sharma, JSS AMC, Mysore, 2005
2. Evaluation of efficacy of Abhraka Bhasma prepared with vasa patra guda paka swarasa as bronchodilator-an experimental study, Dr.Mahanta Swami. S. Hiremath, D.G.M Gadag.2007
3. Screening of aphrodisiac effect of Abhraka Bhasma prepared with ashwagandha-an experimental study, Dr.Deepa. T, D.G.M Gadag.2007
4. Evaluation of analgesic effect of Abhraka Bhasma prepared with dathura patra swarasa-an experimental study. Dr.praveen S Pallad, D.G.M Gadag.2007
5. Evaluation of hepatoprotective effect of Abhraka Bhasma with Bringaraja swarasa-an experimental study.D.G.M Gadag.2007
6. Evaluation of anti-inflammatory effect of Agnimantha maritha abhraka bhasma-an experimental study,Dr.Sanjeev Reddy,D. G. M Gadag. 2008

7.Evaluation of krimihara property of Abhraka Bhasma prepared with kumari swarasa-an experimental

study, Dr Jayakar S , D.G.M Gadag.2008

8.Comparative pharmaceutico-analytical study of Abhraka Bhasma sample prepared with or without

amrithikarana. Arya S Sharma, Muniyal Institute of Ayurvedica Medical Science, Manipal. 2008

9.Evaluation of medhya effect of Shankhapushpi swarasa maritha Abhraka –an experimental study

Dr,Ani dev s,D.G.M college Gadag 2009

10. Evaluation of Haemaetinic effect of Guda maritha Abhraka –An experimental study.Dr.Gigi Mathew

D.G.M College .Gadag2009

11.Pharmaceutical and Analitical study of Tankana maritha Abhraka.Dr.Magadum Amol Subash

Govt.Ayurvedic College Bangalore.

6.3 Aims & objectives of study.

1.To prepare Abhraka Bhasma.

2.To subject the prepared Abhraka Bhasma for Amruteekarana and Lohitikarana

3.To carry out the qualitative and quantitative analysis of Abhraka bhasma before and after Amrithikarana and after Lohithikarana.

7. Materials & Methods

7.1 Source of Data

1. Literary data will be collected from authentic Rasashastra texts,Minerology text,journals and internet.

2. Source of drug from genuine source

3. Analysis done by recongnised labs

7.2 Method of collection of data

PHAMACEUTICAL STUDY

Shodana of Abhraka will be done by heating and Quenching Abhraka in Gokshira for 7 times1

Shoditha Abhraka will be mixed with paddy and tied in a strong cloth then kept in kanji ,pressed vigoursly to get Dhanyaabraka2

Abhraka Bhasma will be prepared by mixing dhanyaabhraka with equal quantity of jaggery ,bhavana done with Eranda patra swarasa ,chakrikkas will be prepared and dried,dried chakkrikas are kept in between vatapatras and wil be placed in sharava and subjected to 3 putas.

Amriteekarana will be done by mixing 10 parts of Abhraka Bhasma .16 parts of Triphalakashaya and 8 parts of Gogritha,kept it in loha patra subjected to heat.

Lohitikarana is done by levigating Abhraka Bhasma with Manjishta Kwatha and subjected to 3 Gajaputas

ANALYTICAL STUDY

1)Bhasma pareeksha -

a)Varitaratwa, b)Rekhapurnatwa, c)Apunarbhava, d)Unnama and e)Nirutha.f)Nischandratwa.

2)Modern parameters -

a) Organoleptic characteristics

b)pH

c) Particle size

d) Acid insolubility

e)Water solubility

f)NPST

INSTRUMENTAL :- a. A.A.S b.XRD

7.3 Does the study require in investigations or interventions to be conducted on patients or other human or animals? If so please describe briefly.

No it does not require.

7.4.Has ethical clearance been obtained from your institution in case of 7.3?

Not applicable

8.Lists of references.

1.Dr.Tripati Indradeva, Rasa Ratna Sanuchaya of Vagbhata, chaukamba sanskrit bhavan, Varanasi, 3rd edition 2006, 2nd chap.P12-13.PP491

2.Dr.Tripati Indradeva, Rasa Ratna Samuchaya of Vagbhata, chaukamba sanskrit bhavan, Varanasi, 3rd edition 2006, 2nd chap .P12-13.PP.491

3.Dr.Tripati Indradeva, Rasa Ratna Samuchaya of Vagbhata, chaukamba sanskrit bhavan, Varanasi ,3rd edition 2006, 2nd chap.P 12-13.PP491

4.Dr. Mishra Siddhinandan. Rasendra Chintamani of Acharya Dundukanatha, Chaukamba orientalia, Varanasi, 2006, 6th chap.P62,PP395

5.Shstry Kashinatha, Rasatarangini of Sharma Sadananda, Motilal Banarasidas,Varanasi,11th edition,1979. 10thchapter, P 232.PP772

9. / Signature of the Candidate
10. / Remarks of the Guide
11. / Name and registration of
11.1 Guide
11.2 Signature
11.3 Co-guide (if any)
11.4 Signature
11.5 Head of the department
11.6 Signature / Dr.V.Shreeshananda Sharma M.D(Ayu)
Asst.Professor
Dept of P.G studies in Rasashastra
J.S.S.Ayurveda Medical College
Mysore -28
Dr.Ashok.D.Satpute MD(Ayu)
Dean,H.O.D and Professor of PG studies
In Rasashastra
JSS Ayurvedic medical college
Mysore.
12.1

12.2 / Remarks of the chairman and principal
Signature