Supplementary Table 1. Human Tdp1 expression.

Male / Female (2 year old) / Female (16 year old)
Cytoplasm / Nucleus / Cytoplasm / Nucleus / Cytoplasm / Nucleus
Thyroid
Follicular cells / +/- / +/- / +/- / +/- / + / +
Parafollicular cells / +/- / +/- / +/- / +/- / +/- / +/-
Parathyroid
Chief cells / + / + / + / + / + / ++
Pancreatic islets / + / +/- / + / + / + / ++
Adrenal cortex
Zona glomerulosa / +++ / +++ / +++ / +++ / +++ / +++
Zona fasiculata / ++ / ++ / ++ / +++ / ++ / ++
Zona reticularis / + / + / + / ++ / + / ++
Adrenal medulla / +++ / +++ / +++ / ++ / ++ / +
Adipose / +++ / +/- / +++ / +/- / ++ / +/-
Esophagus
Strat sq epith / ++ / +++ / +++ / +++ / ++ / ++
Lamina propria / +/- / +/- / +/- / - / + / +/-
Muscularis / + / ++ / + / + / + / ++
Serosa / + / +++ / + / +++ / + / +++
Stomach
Mucosa / +++ / +++ / +++ / +++ / +++ / +++
Muscularis / + / +/- / + / +/- / + / +
Small intestine
Mucosa / +++ / ++ / ++ / +++ / ++ / ++
Muscularis / + / ++ / + / ++ / + / +
Large intestine
Mucosa / +++ / ++ / +++ / ++ / ++ / ++
Muscularis / + / ++ / ++ / ++ / + / +
Liver
Hepatocytes / ++ / ++ / ++ / ++ / ++ / ++
Kupffer cells / +++ / ++ / +++ / ++ / +++ / +++
Bile duct / ++ / + / ++ / + / ++ / +++
Exocrine pancreas
Acinar cell / + / +/- / ++ / +/- / ++ / ++
Kidney
Capsule / + / - / + / +/- / + / +
Glomeruli / + / +/- / + / +/- / + / +/-
Proximal tubules / +++ / ++ / ++ / ++ / ++ / ++
Macula densa / ++ / +/- / ++ / + / ++ / ++
Distal tubules / ++ / + / ++ / + / ++ / +
Loops of Henle / ++ / + / ++ / + / ++ / +
Collecting ducts / +++ / ++ / +++ / ++ / +++ / ++
Bladder
Transitional epith / ++ / +/- / ++ / + / ++ / ++
Smooth muscle / ++ / ++ / ++ / + / ++ / +
Male / Female (2 year old) / Female (16 year old)
Cytoplasm / Nucleus / Cytoplasm / Nucleus / Cytoplasm / Nucleus
Reproductive
Testes
Spermatogonia / +++ / ++ / N/A / N/A / N/A / N/A
Leydig cells / + / +/- / N/A / N/A / N/A / N/A
Sertoli cells / ++ / ++ / N/A / N/A / N/A / N/A
Prostate
Smooth muscle / + / + / N/A / N/A / N/A / N/A
Glands / +++ / ++ / N/A / N/A / N/A / N/A
Epididymus / +++ / ++ / N/A / N/A / N/A / N/A
Ovary
Primary oocyte / N/A / N/A / +++ / + / ++ / ++
Follicular cells / N/A / N/A / + / +/- / ++ / +
Fallopian tube / N/A / N/A / +++ / ++/+ / ++ / +
Heart
Epicardium / + / + / + / + / +/- / +/-
Myocardium / +++ / + / +++ / + / ++ / ++
Endocardium / + / +/- / + / + / +/- / +
Blood vessels
Endothelium / + / + / + / + / ++ / ++
Smooth muscle / + / + / + / + / ++ / ++
Adventitia / - / + / + / + / +/- / ++
Pulmonary
Trachea & Bronchi
Resp epith / + / +/- / +++ / ++ / ++ / +++
Lamina propria / + / +/- / ++ / - / + / +++
Serous/mucinous / ++ / +/- / +++ / ++ / ++ / +++
Alveoli
Type 1 pneumocytes / + / + / + / + / + / +++
Type 2 pneumocytes / + / + / + / + / + / +++
Alveolar macrophage / + / + / ++ / ++ / ++ / +++
Spleen
Red pulp / + / ++ / + / ++ / + / ++
White pulp / + / + / + / + / + / ++
Thymus
Cortex / + / + / + / ++ / N/A / N/A
Medulla / + / + / + / ++ / N/A / N/A
Corpuscle / + / + / + / +/- / N/A / N/A
Bone marrow
Megakaryocyte lineage / + / + / + / ++ / ++ / +/-
RBC lineage / + / - / + / + / + / +/-
WBC lineage / ++ / +++ / ++ / +++ / + / +
Male / Female (2 year old) / Female (16 year old)
Cytoplasm / Nucleus / Cytoplasm / Nucleus / Cytoplasm / Nucleus
Endochondral bone
Periosteum / + / + / + / ++ / + / +
Osteoblasts / + / +++ / + / +++ / ++ / ++
Osteoclasts / +++ / +++ / +++ / ++ / + / +
Growth plate
Prolif zone / +++ / ++ / +++ / ++ / N/A / N/A
Hypertr and calcif. zone / ++ / + / ++ / + / +++ / ++
Hyaline cart / ++ / +++ / ++ / +++ / +++ / +++
Tendon/CT / ++ / ++ / ++ / ++ / N/A / N/A
Skeletal muscle
Myofiber / + / - / + / +/- / + / -
Satellite cell / + / + / + / + / + / +
Fascia / + / + / + / + / +/- / +

Key: +++ = Highly expressed; ++ = Moderately expressed; + = Weakly expressed; - = Not expressed.