Appendix A: Tumor histology and nodal sampling
n / RP / n / VATS / pTumor Focality / Unifocal / 35 / 30 (85.7%) / 69 / 65 (94.2%) / 0.017
Multifocal / 3 (8.6%) / 0
Separate nodules in the same lobe / 0 / 3 (4.3%)
Separate nodules in different lobes / 2 (5.7%) / 0
Indeterminate / 0 / 1 (1.4%)
Tumor type / Adenocarcinoma / 40 / 28 (70%) / 84 / 52 (61.9%) / 0.376
Carcinoid tumor / 6 (15%) / 7 (8.3%)
SCC / 4 (10%) / 16 (19%)
Combined Small cell carcinoma / 1 (2.5%) / 2 (2.4%)
Others / 1 (2.5%) / 7 (8.3%)
Tumor grade / Well differentiated / 36 / 8 (22.2%) / 69 / 11 (15.9%) / 0.684
Moderately differentiated / 20 (55.6%) / 34 (49.3%)
Not present / 21 (63.6%) / 45 (59.2%)
Present / 12 (36.4%) / 27 (35.5%)
Indeterminate / 0 / 4 (5.3%)
Visceral Pleural invasion / Not present / 33 / 21 (63.6%) / 76 / 45 (59.2%) / 0.403
Present / 12 (36.4%) / 27 (35.5%)
Indeterminate / 0 / 4 (5.3%)
Table 4: Hospital-related Costsa
Type / RP / VATS / pn / Mean units used per patients / Direct Medical cost / Direct Non-Medical cost / Total cost / n / Mean units used per patients / Direct Medical cost / Direct Non-medical cost / Total cost
PRE-OPERATIVE / PAACb / 33 (78.6%) / 1.63 ± 0.49 / $103.92 ($20.64) / $24.49 ($5.13) / $128.41 ($25.64) / 55 (57.3%) / 1.63 ± 0.49 / $101.38 ($15.40) / $24.37 ($4.73) / $125.49 ($19.64) / 0.153
CoreLaboratory / 35 (83.33%) / 1.00 / $29.09 ($4.83) / $4.72 ($0.82) / $33.91 ($5.65) / 71 / 1.00 / $31.42 ($2.84) / $5.25 ($0.69) / $36.67 ($3.30) / 0.000
Diagnostic- Non-invasive Cardiology / 36 (85.7%) / 1.00 / $23.20 ($3.31) / $4.42 ($0.74) / $26.62 ($4.03) / 72 (75%) / 1.00 / $23.58 ($3.39) / $4.52 ($0.64) / $28.10 ($3.94) / 0.370
Diagnostic- Radiology / 1 (2.4%) / 1.00 / $67.49 / $16.22 / $83.71 / 2 (2.1%) / 1.00 / $93.34 / $23.07 / $116.41 / 0.221
TOTAL / 37 (88.1%) / $230.05 ($66.42) / $46.63 ($11.92) / $276.99 ($78.43) / 74 (77.1%) / $224.45 ($56.78) / $44.70 ($17.62) / $268.85 ($73.44) / 0.094
INTRA-OPERATIVE / Operating room / 42 (100%) / 1.00 / $4840.38 ($1249.70) / $1464.13 ($611.39) / $6425.34 ($1791.17) / 96
(100%) / 1.02 ± 0.14 / $3859.67 ($929.84) / $875.61 $445.12) / $4754.43 ($1311.34) / 0.000
Anesthetist / 42 (100%) / - / - / - / $903. 60 ($198.13) / 96 (100%) / - / - / - / $582.39 ($260.42) / 0.000
Surgeon-additional procedure / 12 (28.60%) / - / - / -- / $45.85 / 24 (25%) / - / - / - / $45.85 / 1.000
Surgeon Assist / 21 (50%) / - / - / - / $90.30 / 15 (15.6%) / - / - / - / $120.40 ($0) / 0.090
Total Surgeon / 42 (100%) / - / - / $1368.13 ($120.40) / 96 (100%) / -- / - / $1285 ($45.85) / 0.000
Pre-PostRoomc / 42
(100%) / 1.00 / $149.72 ($96.97) / $40 ($29.07) / $190.30 ($125.94) / 96 (100%) / 1.03 ±
0.14 / $98.61 ($79.60) / $25.65 ($25.16) / $124.83 ($104.62) / 0.003
Post-Anesthesia Recovery Roomd / 42 (100%) / 1.00 / 381.29 (179.67) / $70.72 ($33.12) / $453.67 ($211.87) / 96
(100%) / 1.02 ± 0.14 / $407.43 ($204.45) / $75.72 ($32.80) / $483.70
($240.35) / 0.295
TOTAL / 42 (100%) / - / - / - / $9377.37 ($2148.37) / 96
(100%) / - / - / - / $7371.16 ($1737.77) / 0.000
POST-PERATIVE- ALLIED HEALTH / Clinical Nutrition / 7 (16.7%) / 1.14 ± 0.38 / $41.86 ($67.43) / $6.17 ($9.94) / $47.95 ($77.37) / 15 (15.6%) / 2.13 ± 2.03 / $28.23
($183.78) / $4.33 ($27.69) / $32.56 ($211.47) / 0.860
Occupational therapy / 3 (7.1%) / 2.33 ± 0.58 / $46.50 / $10.03 / $56.53 / 12 (12.5%) / 2.67 ± 2.31 / $73.44 ($94.30) / $23.96 ($19.60) / $88.79 / 0.093
Pastoral Care / 12 (28.6%) / 1.25 ± 1.00 / $74.56 ($94.49) / $23.95 ($33.27) / $98.77 ($127.76) / 21 (21.9%) / 1.19 ± 0.40 / $53.49 ($60.93) / $18.90 ($22.41) / $72.39 ($82.85) / 0.512
Physiotherapy / 41 (97.6%) / 4.34 ± 2.89 / $195.19 ($175.90) / $44.60
($42.86) / $242.02 ($218.04) / 94 (97.9%) / 4.09 ± 2.91 / $201.15 ($134.55) / $46.77 ($32.94) / $248.03 ($167.04) / 0.705
Social Work / 2 (4.8%) / 3.5 ± 3.54 / $460.79 / $79.26 / $540.05 / 4 (4.2%) / 2.75 ± 0.50 / $223.43 ($63.61) / $36.06 ($10.23) / $259.49 / 1.000
Speech Language Therapy / 2 (4.8%) / 4.5 ± 2.12 / $360.48 / $82.01 / $442.49 / 4 (4.2%) / 6 ± 3.56 / $283.08 ($294.50) / $65.85 ($66.62) / $348.93 ($361.11) / 1.000
TOTAL / 42 (100%) / - / $205.845 ($247.45) / $47.0350 ($51.785) / $251.38 ($306.67) / 95 (98.96%) / - / $216.34 ($188.70) / $49.81 ($47.86) / $266.67 ($240.14) / 0.685
Postoperative Clinics / Geriatrics / 0 / - / - / - / - / 2 (2.1%) / 1.5 ± 0.71 / $151.04 / $22.20 / $173.23 / -
Hematology / 1 (2.4%) / 4.00 / $207.32 / $69.20 / $276.52 / 4 (4.2%) / 2.5 ± 1.29 / $129.58 ($105.04) / $43.25 ($35.12) / $172.83 ($140.16) / 0.157
POSTOPERATIVE DIAGNOSTICS / Computerized tomography Scan / 4 (9.5%) / 1.00 / $70.14 ($29.46) / $18.40 ($6.14) / $88.25 ($40.05) / 10 (10.4%) / 1.00 / $122.82 ($38.96) / $30.60 ($11.54) / $154.58 ($48.68) / 0.023
Non-Invasive Cardiology / 21 (50%) / 1.95 ± 1.02 / $47.31 ($60.75) / $8.97 ($11.87) / $56.22 ($72.59) / 41 (42.7%) / 2.56 ± 1.73 / $61.08 ($49.54) / $11.70 ($9.52) / $72.78 ($59.05) / 0.169
Radiology / 42 (100%) / 6.52 ± 3.59 / $430.88 ($353.93) / $110.41 ($81.52) / $541.29 ($435.89) / 96 (100%) / 5.61 ± 3.38 / $448.52 ($318.92) / $110.57 ($81.64) / $559.08 ($401.85) / 0.686
Ultrasound / 1 (2.4%) / 1.00 / $92.67 / $17.06 / $109.73 / 1 (1.0%) / 1.00 / $168.09 / $31.18 / $199.27 / 0.317
TOTAL / 42 (100%) / - / $464.42 ($366.57) / $114.32 ($84.64) / $575.45 ($452.86) / 96 (100%) / - / $479.27 ($403.28) / $117.29 ($90.14) / $596.55 ($490.31) / 0.736
POSTOPERATIVE LABORATORY / Anatomy-Pathology / 42 (100%) / 1.07 ± 0.26 / $555.97 ($327.51) / $127.17 ($73.19) / $684.38 ($401.48) / 96 (100%) / 1.14 ± 0.34 / $508.83 ($434.15) / $119.71 ($96.90) / $629.86 ($533.43) / 0.224
Core laboratory / 35 (83.33%) / 6.29 ± 3.01 / $133.36 ($89.83) / $22.16 ($13.57) / $155.52 ($103.40) / 71 (73.96%) / 5.21 ± 3.03 / $116.35 ($76.26) / $19.24 ($12.40) / $135.59 ($87.91) / 0.488
Cytopathology / 0 / - / - / - / - / 2 (2.1%) / 1 / $261.74 / $49.09 / $310.83 / -
Microbiology / 1 (2.4%) / 1 / $306.84 / $102.92 / $409.76 / 1 (1.0%) / 1 / $181.59 / $61.32 / $242.91 / 0.317
Transfusion / 3 (7.1%) / 1.00 / $6.25 / $0.99 / $7.24 / 11 (11.5%) / 1.09 ± 0.30 / $53.27 ($79.41) / $8.28 ($12.58) / $61.48 ($91.99) / 0.185
TOTAL / 42 (100%) / - / $697.28 ($374.48) / $149.57 ($87.31) / $841.59 ($458.45) / 96 (100%) / - / $664.28 ($583.04) / $143.80 ($122.62) / $808.08 ($695.20) / 0.279
POSTOPERATIVE WARD / Intensive Care Unit / 0 / - / - / - / - / 3 (3.1%) / 2.67 ± 2.08 / $5367.86 / $1059.15 / $6427.01 / -
Step Down Unit / 9 (21.4%) / 3.22 ± 2.91 / $3351.32 ($3567.25) / $641.12 ($736.03) / $3992.44 ($4303.27) / 28 (29.2%) / 2.25 ± 1.90 / $1875.46 ($2227.21) / $391.05 ($465.69) / $2250.79 ($2691.39) / 0.128
Hospital Ward / 41 (97.6%) / 5.24 ± 3.49 / $1625.44 ($1962.81) / $393.99 ($458.84) / $2016.49 ($2416.81) / 93 (96.7%) / 4.39 ± 3.13 / $1126.19 ($1318.53) / $295.53 ($332.76) / $1413.11 ($1663.79) / 0.183
TOTAL / 42 (100%) / - / $2583.84 ($3132.06) / $633.21 ($769.31) / $3206.49 ($3837.10) / 96 (100%) / $1850.91 ($2382.64) / $454.06 ($486.87) / $2338.90 ($2843.26) / 0.509
POSTOPERATIVE (OTHERS) / Food / 42 (100%) / 6.81 ± 3.61 / $181.55 ($140.37) / $44.17 ($35.29) / $225.71 ($174.97) / 96 (100%) / 5.98 ± 3.75 / $126.37 ($95.32) / $31.22 ($23.92) / $158.05 ($118.48) / 0.025
Endoscopy / 2 (4.8%) / 1.00 / $367.85 / $133.68 / $501.53 / 2 (2.1%) / 1.5 ± 0.71 / $884.83 / $228.21 / $1113.04 / 0.121
Pharmacy / 42 (100%) / 6.67 ±
3.63 / 298.64 ($239.42) / $87.66 ($63.03) / $383.10 ($291.22) / 96 (100%) / 5.84 ± 3.75 / $265.54 ($267.41) / $60.11 ($60.32) / $326.34 ($308.60) / 0.166
Respiratory Therapist / 5 (11.9%) / 1.4 ±
0.56 / $363.33 ($377.04) / $105.57 ($114.50) / $465.90 ($491.54) / 9 (6.2%) / 2.17 ±
1.17 / $490.56 ($913.31) / $146.52 ($272.81) / $637.08 ($1186.12) / 0.201
aCosts are displayed as median and interquartile range (in brackets) whenever possible; bPre-Admission Assessment Clinic; cPre-Post Recovery is the space a patient is taken to recover after a patient has regained consciousness and is waiting to be assigned a ward unit; dPost-Anesthesia Recovery Room is a space a patient is taken to safely regain consciousness post-surgery.