NAVBO's Vascular Biology Publication Alert

December2015Issue (papers published inNovember 2015)

NAVBO Members are highlighted in dark red

The American Journal of Pathology

Catherine T.K. Le, Grace Laidlaw, Christopher A. Morehouse, Brian Naiman, Philip Brohawn, Tomas Mustelin, Jane R. Connor, Donald M. McDonald.Synergistic Actions of Blocking Angiopoietin-2 and Tumor Necrosis Factor-α in Suppressing Remodeling of Blood Vessels and Lymphatics in Airway Inflammation.Am J Pathol. 185(11):2949–2968

Ning Zhang, Kotha Subbaramaiah, Rhonda K. Yantiss, Xi Kathy Zhou, Yvette Chin, Ellen J. Scherl, Brian P. Bosworth, Robert Benezra, Andrew J. Dannenberg.Id1 Expression in Endothelial Cells of the Colon Is Required for Normal Response to Injury.Am J Pathol. 185(11):2983–2993

Biochemical Journal

No vascular biology related publications this month

Blood

Satish B. Cheepala, Aaron Pitre,Yu Fukuda, Kazumasa Takenaka, Yuanyuan Zhang, Yao Wang, Sharon Frase, Tamara Pestina, T. Kent Gartner, Carl Jackson, and John D. Schuetz. The ABCC4 membrane transporter modulates platelet aggregation.Blood, 126(20):2307-2319

Qi Da, Miho Teruya, Prasenjit Guchhait, Jun Teruya, John S. Olson, and Miguel A. Cruz. Free hemoglobin increases von Willebrand factor–mediated platelet adhesion in vitro: implications for circulatory devices. Blood 126(20), 2338-2341

Cancer Cell

No vascular biology related publications this month

Cancer Research

Langenkamp E, Zhang L, Lugano R, Huang H, Elhassan TE, Georganaki M, Bazzar W, Lööf J, Trendelenburg G, Essand M, Pontén F, Smits A, Dimberg A.Elevated Expression of the C-Type Lectin CD93 in the Glioblastoma Vasculature Regulates Cytoskeletal Rearrangements That Enhance Vessel Function and Reduce Host Survival.Cancer Research, 75(21):4504-4516

Moughon DL, He H, Schokrpur S, Jiang ZK, Yaqoob M, David J, Lin C, Iruela-Arispe ML, Dorigo O, Wu L.Macrophage Blockade Using CSF1R Inhibitors Reverses the Vascular Leakage Underlying Malignant Ascites in Late-Stage Epithelial Ovarian Cancer. Cancer Research, 75(22):4742-4752

Cell

No vascular biology related publications this month

Clinical Science

Marta Toral, Miguel Romero, Rosario Jiménez, Ayman Moawad Mahmoud, Emma Barroso, Manuel Gómez-Guzmán, Manuel Sánchez, Ángel Cogolludo, Ana B. García-Redondo, Ana M. Briones, Manuel Vázquez-Carrera, Francisco Pérez-Vizcaíno, Juan Duarte.Carnitine palmitoyltransferase-1 up-regulation by PPAR-β/δ prevents lipid-induced endothelial dysfunction.Clinical Science, 129(9):823-837

Yee Kwan Chan, Hye Kyoung Sung, Gary Sweeney. Iron metabolism and regulation by neutrophil gelatinase-associated lipocalin in cardiomyopathy.Clinical Science, 129(10):851-862

Development

Risebro, C.A., Vieira, J.M., Klotz, L. & Riley, P.R. Characterisation of the human embryonic and foetal epicardium during heart development.Development, 142:3630-3636

Yung, A.R., Nishitani, A.M. & Goodrich, L.V. Phenotypic analysis of mice completely lacking netrin 1. Development, 142:3686-3691

Developmental Biology

Akerberg, B.N., Sarangam, M.L. & Stankunas, K. Endocardial Brg1 disruption illustrates the developmental origins of semilunar valve disease. Developmental Biology, 407(1):158-172

Bowen, C.J., Zhou, J., Sung, D.C. & Butcher, J.T. Cadherin-11 coordinates cellular migration and extracellular matrix remodeling during aortic valve maturation. Developmental Biology, 407(1):145-157

Developmental Cell

Vera-Sirera, F. et al. A bHLH-Based Feedback Loop Restricts Vascular Cell Proliferation in Plants. Developmental Cell, 35(4):432-443

Developmental Dynamics

No vascular biology related publications this month

EMBO

No vascular biology related publications this month

EMBO Reports

No vascular biology related publications this month

FASEB Journal

N. S. Kirkby, D. M. Reed, M. L. Edin, F. Rauzi, S. Mataragka, I. Vojnovic, D. Bishop-Bailey, G. L. Milne, H. Longhurst, D. C. Zeldin, J. A. Mitchell and T. D. Warner. Inherited human group IVA cytosolic phospholipase A2 deficiency abolishes platelet, endothelial, and leucocyte eicosanoid generation. FASEB J, 29:4568-4578

F. Lavatelli, E. Imperlini, S. Orru, P. Rognoni, D. Sarnataro, G. Palladini, G. Malpasso, M. E. Soriano, A. Di Fonzo, V. Valentini, M. Gnecchi, S. Perlini, F. Salvatore and G. Merlini. Novel mitochondrial protein interactors of immunoglobulin light chains causing heart amyloidosis. FASEB J, 29:4614-4628

N. A. Rohner, J. McClain, S. L. Tuell, A. Warner, B. Smith, Y. Yun, A. Mohan, M. Sushnitha and S. N. Thomas. Lymph node biophysical remodeling is associated with melanoma lymphatic drainage. FASEB J, 29:4512-4522

Genes & Development

No vascular biology related publications this month

Journal of Biological Chemistry

S. P. Sasi, J. Song, D. Park, H. Enderling, J. T. McDonald, H. Gee, B. Garrity, A. Shtifman, X. Yan, K. Walsh, M. Natarajan, R. Kishore and D. A. Goukassian. TNF-TNFR2/p75 signaling inhibits early and increases delayed nontargeted effects in bone marrow-derived endothelial progenitor cells. J Biol Chem, 290:27014

N. Koyano-Nakagawa, X. Shi, T. L. Rasmussen, S. Das, C. A. Walter and D. J. Garry. Feedback Mechanisms Regulate Ets Variant 2 (Etv2) Gene Expression and Hematoendothelial Lineages. J Biol Chem, 290:28107-28119

K. H. Lee, C. H. Lee, J. Jeong, A. H. Jang and C. G. Yoo. Neutrophil Elastase Differentially Regulates Interleukin 8 (IL-8) and Vascular Endothelial Growth Factor (VEGF) Production by Cigarette Smoke Extract. J Biol Chem, 290:28438-28445

Journal of Cell Biology

Li H, Koo Y, Mao X, Sifuentes-Dominguez L, Morris LL, Jia D, Miyata N, Faulkner RA, van Deursen JM, Vooijs M, Billadeau DD, van de Sluis B, Cleaver O, Burstein E. Endosomal sorting of Notch receptors through COMMD9-dependent pathways modulates Notch signaling. J Cell Biol., 211(3):605-17

Park H, Lee S, Shrestha P, Kim J, Park JA, Ko Y, Ban YH, Park DY, Ha SJ, Koh GY, Hong VS, Mochizuki N, Kim YM, Lee W, Kwon YG. AMIGO2, a novel membrane anchor of PDK1, controls cell survival and angiogenesis via Akt activation.J Cell Biol., 211(3):619-37

Journal of Cell Science

Yukiura H, Kano K, Kise R, Inoue A, Aoki J. LPP3 localizes LPA6 signalling to non-contact sites in endothelial cells. J Cell Sci., 128(21):3871-7

Journal of Clinical Investigation

Cui Y, Liu K, Monzon-Medina ME, Padera RF, Wang H, George G, Toprak D, Abdelnour E, D'Agostino E, Goldberg HJ, Perrella MA, Forteza RM, Rosas IO, Visner G, El-Chemaly S. Therapeutic lymphangiogenesis ameliorates established acute lung allograft rejection.J Clin Invest., 125(11):4255-68

Journal of Experimental Medicine

Briot A, Civelek M, Seki A, Hoi K, Mack JJ, Lee SD, Kim J, Hong C, Yu J, Fishbein GA, Vakili L, Fogelman AM, Fishbein MC, Lusis AJ, Tontonoz P, Navab M, Berliner JA, Iruela-Arispe ML. Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis. J Exp Med., 212(12):2147-63

Journal of Immunology

Hu R, Chen ZF, Yan J, Li QF, Huang Y, Xu H, Zhang XP, Jiang H. Endoplasmic Reticulum Stress of Neutrophils Is Required for Ischemia/Reperfusion-Induced Acute Lung Injury.J Immunol., 195(10):4802-9

Baruzzi A, Remelli S, Lorenzetto E, Sega M, Chignola R, Berton G. Sos1 Regulates Macrophage Podosome Assembly and Macrophage Invasive Capacity. J Immunol., 195(10):4900-12

Liu M, Luo F, Ding C, Albeituni S, Hu X, Ma Y, Cai Y, McNally L, Sanders MA, Jain D, Kloecker G, Bousamra M 2nd, Zhang HG, Higashi RM, Lane AN, Fan TW, Yan J. Dectin-1 Activation by a Natural Product β-Glucan Converts Immunosuppressive Macrophages into an M1-like Phenotype. J Immunol., 195(10):5055-65

Journal of Lipid Research

No vascular biology related publications this month

Molecular and Cellular Biology

No vascular biology related publications this month

Molecular Biology of the Cell

No vascular biology related publications this month

Nature

Christopher N. Inra, Bo O. Zhou, Melih Acar, Malea M. Murphy, James Richardson, Zhiyu Zhao and Sean J. Morrison.A perisinusoidal niche forextramedullary haematopoiesis in the spleen.Nature, 527(7579):466–471

Nature Cell Biology

No vascular biology related publications this month

Nature Genetics

No vascular biology related publications this month

Nature Medicine

No vascular biology related publications this month

PNAS

Jensen LD, Nakamura M, Bräutigam L, Li X, Liu Y, Samani NJ, Cao Y. VEGF-B-Neuropilin-1 signaling is spatiotemporally indispensable for vascular and neuronal development in zebrafish. Proc Natl Acad Sci U S A, 112(44):E5944-53

Cullere X, Plovie E, Bennett PM, MacRae CA, Mayadas TN.The cerebral cavernous malformation proteins CCM2L and CCM2 prevent the activation of the MAP kinase MEKK3.Proc Natl Acad Sci U S A, 112(46):14284-9

Tolaney SM, Boucher Y, Duda DG, Martin JD, Seano G, Ancukiewicz M, Barry WT, Goel S, Lahdenrata J, Isakoff SJ, Yeh ED, Jain SR, Golshan M, Brock J, Snuderl M, Winer EP, Krop IE, Jain RK. Role of vascular density and normalization in response to neoadjuvant bevacizumab and chemotherapy in breast cancer patients. Proc Natl Acad Sci U S A, 112(46):14325-30

Takeuchi M, Fuse Y, Watanabe M, Andrea CS, Takeuchi M, Nakajima H, Ohashi K, Kaneko H, Kobayashi-Osaki M, Yamamoto M, Kobayashi M. LSD1/KDM1A promotes hematopoietic commitment of hemangioblasts through downregulation of Etv2.Proc Natl Acad Sci U S A, 112(45):13922-7

Gao X, Zhao Y, Stemmer-Rachamimov AO, Liu H, Huang P, Chin S, Selig MK, Plotkin SR, Jain RK, Xu L. Anti-VEGF treatment improves neurological function and augments radiation response in NF2 schwannoma model.Proc Natl Acad Sci U S A., 112(47):14676-81

Zilberberg L, Phoon CK, Robertson I, Dabovic B, Ramirez F, Rifkin DB.Genetic analysis of the contribution of LTBP-3 to thoracic aneurysm in Marfan syndrome.Proc Natl Acad Sci U S A., 112(45):14012-7

Science

Ilaria Spadoni, Elena Zagato, Alice Bertocchi, Roberta Paolinelli, Edina Hot, Antonio Di Sabatino, Flavio Caprioli, Luca Bottiglieri, Amanda Oldani, Giuseppe Viale, Giuseppe Penna, Elisabetta Dejana, and Maria Rescigno.A gut-vascular barrier controls the systemic dissemination of bacteria. Science, 350(6262):830-834

Member Submissions

Kuo KC, Lin RZ, Tien HW, Wu PY, Li YC,Melero-MartinJM, Chen YC.Bioengineering vascularized tissue constructs using an injectable cell-laden enzymatically crosslinkedcollagen hydrogel derived from dermal extracellular matrix.Acta Biomater., 27:151-66

Lin Xiao, James VMcCann,Andrew CDudley.Isolation and Culture Expansion of Tumor-specific Endothelial Cells.J Vis Exp., 104

Nurmi H, Saharinen P, Zarkada G, Zheng W, Robciuc MR, Alitalo K. VEGF-C is required for intestinal lymphatic vessel maintenance and lipid absorption.EMBO Mol Med., 7(11):1418-25

Libby P.Murine "model" monotheism - an iconoclast at the altar of mouse. Cir Res., 117:921-925

Xiofeng Cui, Yao Wei Lu, Vivian Lee, Diana Kim, Taylor Dorsey, Qingjie Wang, Young Lee, Peter Vincent, John Schwarz, Guohao Dai.Venous Endothelial Marker COUP-TFII Regulates the Distinct Pathologic Potentials of Adult Arteries and Veins. Sci Rep.,5:16193

Fu BM,Yang J, Cai B, Fan J, Zhang L, Zeng M.Reinforcing endothelial junctions prevents microvessel permeability increase and tumor cell adhesion in microvessels in vivo.Sci Rep., 5:15697

Deng L, Blanco FJ, Stevens H, Lu R, Caudrillier A, McBride M, McClure JD, Grant J, Thomas M, Frid M, Stenmark K, White K, Seto AG, Morrell NW, Bradshaw AC, MacLean MR, Baker AH.MicroRNA-143 Activation Regulates Smooth Muscle and Endothelial Cell Crosstalk in Pulmonary Arterial Hypertension.Circ Res., 117(10):870-83

Stein-Merlob AF, Kessinger CW, Erdem SS, Zelada H, Hilderbrand SA, Lin CP, Tearney GJ, Jaff MR, Reed GL, Henke PK, McCarthy JR, Jaffer FA.Blood Accessibility to Fibrin in Venous Thrombosis is Thrombus Age-Dependent and Predicts Fibrinolytic Efficacy: An In Vivo Fibrin Molecular Imaging Study. Theranostics, 5(12):1317-27

He S, Chousterman BG, Fenn A, Anzai A, Nairz M, Hilgendorf I, Sun Y, Ye Y, Iwamoto Y, Tacrot B, Weissleder R, Macphee C, Libby P, Nahrendorf M, Swirski FK. Lp-PLA2 antagonizes left ventricular healing after myocardial infarction by impairing the appearance of reparative macrophages. Circ Heart Fail, 8(5):980-987

Qin Z, Bagley J, Sukhova G, Baur WE, Park H, Beasley D, Libby P, Zhang Y, Galper JB. Angiotensin II-induced TLR4 mediated abdominal aortic aneurysm in Apolipoprotein E knockout mice is dependent on STAT3. J Moll Cell Cardiol., 87:160-170

Nakatsuji M, Minami M, Seno H, Yasui M, Komekado H, Higuchi S, Fujikawa R, Nakanishi Y, Fukuda A, Kawada K, Sakai Y, Kita T, Libby P, Ikeuchi H, Yokode M, Chiba T. EP4 receptor–associated protein in macrophages 1 ameliorates colitis 2 and colitis-associated tumorigenesis. PLOS Genetics, 11(10): e1005542

Rose KL, Watson AJ, Drysdale TA,CepinskasG, Chan M, Rupar CA, Fraser DD. Simulated diabetic ketoacidosis therapy in vitro elicits brain cell swelling via sodium-hydrogen exchange and anion transport. Am J Physiol Endocrinol Metab., 309(4):E370-9

Dutta P, Hoyer FF, Grigoryeva LS, Sager HB, Leuschner F, Courties G, Borodovsky A, Novobrantseva T, Ruda VM, Fitzgerald K, Iwamoto Y, Wojtkiewicz G, Sun Y, Da Silva N, Libby P, Anderson DG, Swirski FK, Weissleder R, Nahrendorf M. Macrophages retain hematopoietic stem cells in the spleen via VCAM-1. J Exp Med, 212(4):497-512

Dutta P, Sager HB, Stengel KR, Naxerova K, Courties G, Saez B, Silberstein L, Heidt H, Sebas M, Sun Y, Wojtkiewicz G, Feruglio PF, King K, Baker JN, van der Laan AM, Borodovsky A, Fitzgerald K, Hulsmans M, Hoyer F, Iwamoto Y, Vinegoni C, Brown D, Di Carli M, Libby P, Hiebert S, Scadden D, Swirski FK, Weissleder R, Nahrendorf M.Myocardial infarction activates CCR2+ hematopoietic stem and progenitor cells. Cell Stem Cell, 16(5):477-487

Fordyce CB, Roe MT, Ahmad T, Libby P, Borer JS, Hiatt WR, Bristow MR, Packer M, Wasserman SM, Braunstein N, Pitt B, DeMets DL, Cooper-Arnold K, Armstrong PW, Berkowitz SD, Scott R, Prats J, Galis ZS, Stockbridge N, Peterson ED, Califf RM. Cardiovascular drug development: Is it dead or just hibernating? J Am Coll Cardiol., 65(15):1567-1582

Zhou Y, Wu W, Lindholt JS, Sukhova GK, Libby P, Yu X, Shi GP. Regulatory T cells in human and angiotensin II-induced mouse abdominal aortic aneurysms. Cardiovasc Res, 107(1):98-107