CURRICULUM VITAE
PERSONAL DATA
Name: Reem Abdul Majeed Kanaan
Place & Date of Birth: Kuwait, January 17, 1970
Citizenship: Jordanian
Phone: Home 9626-5663-501, Cell 079-503-4547
E-Mail: .
EDUCATION
2006-2003 Post Doctoral Fellow, University of Pennsylvania, School of
Medicine, Orthopedic surgery, Philadelphia, PA, USA.
2000-2004 Ph.D. Anatomy and Cytology
Temple University, School of Medicine, Philadelphia, PA, USA
1987-1991 B.Sc. Agriculture Sciences, Department of Soil & Irrigation,
University of Jordan, Jordan.
2009-2010 MA Erasmus Mundus Master of Bioethics
K.U. Leuven University - School of Medicine -Centre for
Biomedical Ethics and Law Faculty of Medicine-Belgium.
Radboud University Faculty of Medicine – Universitair Medisch Centrum St, Radboud, healthcare IQ Medical Ethics
Netherland.
University of Padova-Department of Philosophy-Italy.
EMPLOYMENT
2012-Currently Assistant Professor at School of Pharmacy –Philadelphia University
2006 - 2012 Assistant Professor, Al- Zaytooneh University, Faculty of
Pharmacy, Lecturer in Physiology, Anatomy, Biology, Pathology,
Histopathology Lab, and Herbal medicine.
1999-2003 Graduate student in Anatomy and Cytology, Temple University,
School of Medicine, Philadelphia, PA, USA.
DISTINCTION HONORS and AWARDS
1999 Temple University Fellowship
2000 Best Poster Presentation, Dawn B.Mark Research Conference,
Temple University School of Medicine.
2008 Outstanding Research Presentation, at the first annual Graduate
Student Research Day competition, Temple University School of
Medicine.
2001 Young investigator travel award , Skeletal Genetics Conference,
Washington DC.
2002 Best Poster Presentation, Dawn B. Mark Research Conference,
Temple University School of Medicine.
2008
Poster Presentation Award, Bone and Mineral Research Conference,
Annual meeting, San Antonio, Texas.
2002 Third place research presentation at the second annual Graduate
Student Research Day competition, Temple University School of
Medicine.
2003 Presentation Award, Second international workshop on CCN
family of Genes, Saint-Malo, France.
2008 Poster Presentation Award, Biomedical PostDoc Research
symposium BMP2 signaling pathways mediate Gnas transcriptional
regulation in C2C12 cells: Implications for progressive osseous
heteroplasia.
2008 Poster Presentation Award, Jordanian International Pharmaceutical
Conference, Nov 15-17, 2006 that will be held at the Faculty of
Pharmacy, Al-Zaytoonah Private University of Jordan.
2008 Mediator at Jordanian International Pharmaceutical Conference,
October 15-17, 2008 that will be held at the Faculty of Pharmacy, Al-
Zaytoonah Private University of Jordan.
· 20-22/12- 2012المؤتمر الدولي حول الفساد والأمن الإنسان والحراك المجتمعي / الكرك – جامعة مؤتة – الاردن
بتقديم ورقة علمية بعنوان " – مفهوم الحرية بالإسلام والفرق بينها وبين مبدأ الحرية الغربي –" في الفترة الواقعة ما بين –
· 2012 عمان 6 حزيران (بترا)- انطلقت في عمان اليوم فعاليات المؤتمر الوطني الخامس تحت عنوان " كيف نحقق رؤى جلالة الملك في بناء الأردن الحديث في مجال التنمية الشاملة "بتنظيم من مركز التفكير الابداعي للتنمية الذاتية والبشرية.وقامت د. ريم كنعان بتقديم ورقة علمية بعنوان تمكين المرأة سياسياً واجتماعياً
2014 Presentation Award, Science day, Faculty of Science, Philadelphia university, Ethics of In vitro fertilization (IVF) 22/5/2014
2014 Presentation Award, On behalf of Dr. Dr.Emad Al-Qaryouti ,
Science day, Faculty of Pharmacy, Philadelphia university, Calcium & Vitamin D In Osteoporosis 20/4/2014
PUBLICATIONS:
A-Research Articles:
1. Hisham Y. Al-Matubsi, Reem A. Kanaan, Farqad Hamdan, Maher Salim, Ghaleb A. Oriquat, Othman A. Al-Hanbali: Smoking Practices in Jordanian People and their Impact on Semen Quality and Hormonal Levels among Adult Men. Cent Eur J Public Health. 2011;19(1):54-59
2. Maswadeh M Hamzah, Kanaan A Reem, Aljarbou N Ahmad and Al-Hanbali A Othman. Effect of Different Biological Membranes on In Vitro Bioadhesion Property. Drug Invention Today,Vol 2, No 2 (2010)
3. Renno WM, Alkhalaf M, Mousa A, Kanaan RA. A Comparative Study of Excitatory and Inhibitory Amino Acids in Three Different Brainstem Nuclei.
Neurochem Res. 2008 Jan;33(1):150-9. Epub 2007 Oct 17.
4. Maswadeh HA, Al-Hanbali OA, Kanaan RA, Shakya AK, Maraqa A.
Testing lyoequivalency for three commercially sustained-release tablets containing diltiazem hydrochloride. Acta Pol Pharm. 2010 Jan-Feb;67(1):93-7.
5. Fayez F. Safadi, Jie Xu, Steve L. Smock, Reem Kanaan, Abdulhafez Selim, Paul R. Odgren, Sandy C Marks, Jr. Thomas A. Owen and Steven N. Popoff. Expression of CTGF in Bone: It’s Role in Osteoblast Proliferation and Differentiation in Vitro and Bone Formation in vivo. J. Cell. Physiol. 196, 51-62, 2003.
6. Selim AA, Abdelmagid SM, Kanaan RA, Smock SL, Owen TA, Popoff SN, Safadi FF. Anti-osteoactivin antibody inhibits osteoblast differentiation and function in vitro. Crit Rev Eukaryot Gene Expr.13, 265-75, 2003.
7. Song JJ, Aswad R, Kanaan RA, Rico MC, Owen TA, Barbe MF, Safadi FF, Popoff SN. Connective tissue growth factor (CTGF) acts as a downstream mediator of TGF-beta1 to induce mesenchymal cell condensation. J Cell Physiol. 2007 Feb; 210(2):398-410.
B-Reviews:
1. Kanaan RA, kanaan LA. Transforming growth factor beta1, bone connection.
Med Sci Monit. 2006 Aug;12(8):RA164-9. Epub 2006 Jul 12. Review.
PMID: 16865078 [PubMed - indexed for MEDLINE]
2. Kanaan RA, Aldwaik M, Al-Hanbali OA. The role of connective tissue growth factor in skeletal growth and development. Med Sci Monit. 2006 Dec; 12(12):RA277-281. Epub 2006 Nov 23. Review.
C-Conference Proceedings:
1- F. F. Safadi, D.T. Yucha, R.A. Kanaan, D. R. Healy, Y. Li, S.L. Smoke, and S.N. Popoff, T.A. Owen. The role of connective tissue growth factor (CTGF) in a fracture repair model in the rat. Presented at the 22nd Annual meeting of American Society for Bone and Mineral Research, Journal of Bone and Mineral Research, Vol.15, SU143,2000. Anatomy and Cell Biology, Temple University School of Medicine, Philadelphia, PA, USA.
2- F. F. Safadi, A. H. Selim, V. Zakhaleva, R. Kanaan, A. Ravindra, M. D'Angelo, S. L. Smock, T. A. Owen, S. N. Popoff. Osteoactivin: A Novel Factor That Regulates Osteoblast Development and Function. Presented at the 23nd Annual meeting of American Society for Bone and Mineral Research, Journal of Bone and Mineral Research, Vol.15, M260, 2001. Anatomy and Cell Biology, Temple University School of Medicine, Philadelphia, PA, USA, 2Cardiovascular and Metabolic Diseases, Pfizer Global Research and Development, Groton, CT, USA.
3- R.A. Kanaan, P. Ebrahimpour, S.L. Smoke, T.A. Owen, and S.N. Popoff and F.F. Safadi, The effect of connective tissue growth factor (CTGF) on differentiation and adhesion of MC3T3-E1 osteoblast like cells. Presented as a poster at the 24nd Annual meeting of American Society for Bone and Mineral Research, Journal of Bone and Mineral Research, Vol.15, SU209, 2002. Anatomy and Cell Biology, Temple University School of Medicine, Philadelphia, PA, USA,
4-Popoff, S. N., Kanaan, R. A., Selim, A. H., Smock, S. L., Owen, T. A. and Safadi,
F. F. (2002) The role of connective tissue growth factor (CTGF) on osteoblast
development and bone formation. Workshop Frontiers of Skeletal Biology. Bone
Journal, 30:3 (suppl) C37.
5- Safadi, F. F., Rico, M. R., Selim, A. H., Kanaan, R. A., Smock, S. L., Owen T. A.
and Popoff, S. N. (2002) Osteoactivin, a novel factor involved in osteoblast
development and function. Workshop Frontiers of Skeletal Biology. Bone
Journal, 30:3 (suppl) C40.
6- Safadi, F. F., Kanaan, R. A., Ebrahimpour, Smock, S. L., Owen T. A. and Popoff,
S. N. (2002) The integrin avb5 mediates osteoblast adhesion to connective tissue
growth factor. Second International Workshop on the CCN Family of Genes,
Saint- Malo, France.
7- R. A. Aswad, M. C. Rico, R. A. Kanaan, H. Devlin F. F. Safadi, and S.N. Popoff Connective tissue growth factor (CTGF) expression during diabetic wound healing in a Tooth extraction model. Presented as a poster at the 25nd Annual meeting of American Society for Bone and Mineral Research, Journal of Bone and Mineral Research, Vol.18, SU202, 2003. Anatomy and Cell Biology, Temple University School of Medicine, Philadelphia, PA, USA,
8- Safadi, F. F., Kanaan R. A., Popoff, S. N. (2003) The Role of Connective Tissue
Growth Factor in Mesenchymal Cell Condensation. (submitted for Experimental
Biology Meeting, April, 2004, Washington DC).
9- J. J. Song, R. A. Kanaan, F. F. Safadi, S. N. Popoff Connective Tissue Growth Factor (CTGF) Mediates Condensation of Mesenchymal Stem Cells Induced by TGF-β1. Presented as a poster at the 26nd Annual meeting of American Society for Bone and Mineral Research, Journal of Bone and Mineral Research, Vol.19, SU206, 2004. Anatomy and Cell Biology, Temple University School of Medicine, Philadelphia, PA, USA, Orthopaedics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.
10- R. A. Kanaan, W. S. Kuo, F. S. Kaplan, R. J. Pignolo, E. M. Shore. GNAS is an Osteoblast Fate Suppressor Gene in Soft Connective Tissue
Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA, USA, Medicine, University of Pennsylvania, Philadelphia, PA, USA, Orthopaedic Surgery and Genetics, University of Pennsylvania, Philadelphia, PA, USA. Presented as a poster at the 26nd Annual meeting of American Society for Bone and Mineral Research, Journal of Bone and Mineral Research, Vol.19, M265, 2004.
11- R. A. Kanaan, B. Saucy, F. S. Kaplan, E. M. Shore. Myoblasts Are Not the Likely Primary Target Cells of Gsα Inactivating Mutations in Progressive Osseous Heteroplasia. Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA, USA, University of Pennsylvania, Philadelphia, PA, USA. 28nd Annual meeting of American Society for Bone and Mineral Research. SU415, 2006.
12- R. A. Kanaan1, O.A.Al-Hanbali1, F. S. Kaplan2, E. M. Shore2. Progressive Osseous Heteroplasia.1-Faculty of Pharmacy, Al-Zaytoonah University, Jordan
2- Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA, USA, University of Pennsylvania, Philadelphia, PA, USA The Third Conference of Jordanian Medical Faculties. Mutah University, Oral presentation.
13-Kanaan, R.A., F.S. Kaplan, and E.M. Shore. BMP2 signaling pathways mediate Gnas transcriptional regulation in C2C12 cells: Implications for POH disease. (Presented at University of Pennsylvania 4th Annual Postdoctoral Research Symposium. Philadelphia, PA; October 21, 2005. )
GRADUATE STUDENTS SUPERVISED (AS CO-ADVISOR)
Samya Abdel-Kareem Omoush
Histological Changes of Reproductive Organs Following Spinal Cord Injury in Adult Male Rats.
Deanship of Scientific Research and Graduate Studies at the Hashemite University
Zarqa – Jordan
TECHNICAL RESEARCH LABORATORY SKILLS
A-Animal surgery
Local injection of different anabolic agents into rat’s femur.
B-Tissue culture
1-Primary cells and cell lines.
2-Establishment of stably transfected cell lines.
3-MinElute Gel extraction.
4-Plasmid DNA Transformation.
5-Anti-sense oligo-transfection in primary cell culture.
6-Plasmid Gega prep, Maxiprep.
7-Si RNA transfection
C-Assays
1-Adhesion assay
2-Calcium assay
3-Alkaline phosphatase activity assay.
4-Proliferation assay: MTT assay.
D-RNA
1-RNA isolation using Trizol method.
2-RT-PCR.
3-Real time PCR
4-Northern blot analysis.
5-Insitu hybridization.
6-Riboprobe synthesis
E-Protein
1-Protein isolation using Trizol method or Riba buffer.
2-Western blot analysis.
3-The Bicinchoninic acid (BCA) protein assay.
4-cAMP Enzymeimmunoassay Biotrak
5-Immunohistochemistry and Immuno-fluresence staining.
6-P38 MAP kinase Assay kit. (Cat #9820). Cell signaling.
3