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CURRICULUM VITAE

NABIL EL-SHERIF, M.D.

Personal:

Address: 160 East 65th Street, Apt.26C, New York, N.Y. 10021

Martial Status: Married, four children

Citizenship: U.S.A

Tel/Fax: (718) 630-3740, (718) 270-4106

E-mail:

EDUCATION:

Faculty of Medicine, Cairo University, Cairo, Egypt, 1953-1959

M.B., B.Ch., December 1959

POST GRADUATE DEGREES:

Diploma of Internal Medicine, Cairo University, 1962

Diploma of Cardiovascular Diseases, Cairo University, 1963

Doctor of Medicine Thesis: "Comparative Study of Orthogonal and

Scalar Electrocardiology", Cairo University, 1965

Doctor of Medicine Degree in Internal Medicine, Subspecialty:

Cardiovascular Diseases, Cairo University, 1965

CERTIFICATION:

Diplomate of the American Board of Internal Medicine, 1975.

Diplomate of the American Board of Cardiovascular Disease, 1975

Diplomate of the American Board of Clinical Cardiac Electrophysiology, 1995

(Recertified 2005)

HOSPITAL and UNIVERSITY AFFILIATIONS:

Visiting Professor University of Chicago, EP Program

1990-January 1991

Chief, Cardiology Division Veterans Administration Medical Center

October, 1978 - present

Associate Vice Chairman SUNY, Health Science Center at

for Research Brooklyn, March 1986 - 2005

Director of Electrophysiology Program SUNY Health Science Center at

Brooklyn, March 1986- 2005

Chief, Cardiology Division SUNY, Downstate Medical Center

Feb. 1984 - March 1986

Attending Physician Kings County Hospital, 1984- present

Professor Department of Medicine, SUNY, Downstate

Medical Center, October 1978 - present


Professor Department of Physiology, Graduate

School, SUNY, Downstate Medical Center

1983 - present

Associate Professor Department of Physiology, Graduate

School, SUNY Downstate Medical Center,

1979 - 1983

Associate Professor Department of Medicine, University of

Miami School of Medicine, June 1976 -

October 1978

Assistant Professor Department of Medicine, University of

Miami School of Medicine, July 1974 -

May 1976

Director, Coronary Care Unit Veterans Administration Hospital, Miami,

Florida July 1974 - October 1978

Research Associate Department of Cardiology, Mount Sinai

Medical Center, Miami Beach, Florida,

July 1973 - June 1974

Fellow in Cardiology Department of Cardiology, Mount Sinai

Medical Center, Miami Beach, Florida,

July 1972 - June 1973.

Assistant Professor Cardiology Department, Faculty of

Medicine, Cairo University, 1972 - 1974

Lecturer in Cardiology Cardiology Department , Faculty of

Medicine, Cairo University, 1967 - 1972

Staff Cardiologist and Cardiology Department , Cairo

Assistant Director of University Hospital 1963 - 1972.

Hemodynamic Laboratory

Clinical Demonstrator Cardiology Department , Faculty of

Medicine, Cairo University, 1963 - 1967

Visiting Registrar Cardiology Department , Hammersmith

Hospital, London, 1963 - 1964

Resident Department of Medicine, Cairo University

Hospital, 1961 - 1963

Intern Cairo University Hospital, 1960 - 1961

SOCIETY MEMBERSHIP:

American Association for the Advancement of Science

American College of Cardiology

American College of Chest Physician

American College of Physicians

American Federation for Clinical Research

American Heart Association

American Physiological Society

Cardiac Electrophysiology Society

Council on Basic Science, American Heart Association

National Association of VA Cardiologists

National Association of VA Physicians

National Electrophysiology Group

New York Academy of Science

New York Heart Association Electrophysiology Group

North American Society of Pacing and Electrophysiology

Sigma Xi Society, SUNY/HSC at Brooklyn Chapter

Albanian Society of Cardiology, Honary Member

OTHER ASSIGNMENTS:

Editorial Board,

1) Journal, American College of Cardiology, 1983 - 1987;

2) Journal of Electrophysiology, 1987-1989.

3) American Journal of Non-Invasive Cardiology 1989-present.

4) Journal of Cardiovascular Electrophysiology,1990-present.

5) PACE, 1990-present

6) New Trends in Arrhythmias , 1991-present

7) Journal of Cardiovascular Pharmacology and Therapeutics, 1995-present

8) Journal of Interventional Cardiac Electrophysiology, 1996-present

9) The Egyptian Heart Journal, 1998-present

10) Mediterranean Journal of Pacing and Electrophysiology (Co-Editor) 1998-present

11) The Open Pacing, Electrophysiology & Therapy Journal, 2008-present

12) Heart Rhythm Journal, 2008-present

Consultant, National Heart, Lung and Blood Institutes, 1974 - 1976

Reviewer, American Journal of Cardiology, American Heart Journal, Circulation, Circulation Research, Chest, European Journal of Cardiology, Pace, Science, American Journal of Physiology, etc..

Director, Annual Electrocardiography Course, Greater Miami Heart Association, 1974 - 1978.

Director, Course on "Cardiac arrhythmias in acute myocardial infarction",

American Heart Association, Miami Beach, 1977

Cardiovascular Program Specialist, VA Central Office, Research Program 1981 - 1984

Acting ACOS/Research and Development, BVAMC, Brooklyn, N.Y.,1984-1986.

Chairman, Research and Development Committee, VAMC, Brooklyn, N.Y., 1980-1982, 1984 - 1988, 1991- 1994

Director, International Symposium on High Resolution EKG, Late Potentials and Noninvasive Electrophysiology”, Nice, France, June 1990: June 1992; June 1994, June 1996.

Co-Director: International Symposium on “Management of Cardiac Arrhythmias”. Lille, France, Nov. 1995.

Co-Director: International Symposium on “Atrial Flutter and Fibrillation. From Basics to Clinical Application”. Heidelberg, Germany, Oct. 1996

Director: International Symposium on “Recent Advances in Diagnosis and Management of Cardiac Arrhythmias”.

Cairo , Egypt, Feb. 1997.

Co-Director: International Cardiovascular Symposium Beijing, P.B. China, Oct, 1998.

Director: International Symposium on Signal Averaged EKD and Late Potentials, CardioStim , 1990, 1992, 1994, 1996, 1998, Nice, France.

Director: International Symposium on Signal Averaged EKD and Late Potentials, and Noninvasive Electrophysiology, Cardiostim, 2000, 2002, 2004, Nice, France

Ph.D. Thesis Completed in the Cardiovascular Research Laboratory

1.  Robert H. Zeiler: “The Electrophysiologic and Contractile Responses of Canine Atrial Tissue to Adrenocorticotropin: Adrenergic and Cholinergic Systems: (Ph.D. in Physiology, 1981).

2.  Mark Restivo: “A Model of Reentrant Ventricular Activation” (Ph.D. in Biomedical Engineering, 1987).

3.  Raphael Henkin: “The Signal Averaged Electrocardiogram: Spectrotemporal Mapping” (Ph.D. in Biomedical Engineering, 1990).

4.  Maha Hegazy: “Experimental Models of Atrial Flutter” (Ph.D. in Physiology, 1995).

5.  Edward Benjamin Caref: “Computer-Based Techniques for Cardiac Mapping and Electrogram Analysis “ (Ph.D. in Biomedical Engineering, 1996).

6.  Boyu Huang: “Alterations in Sarcolemmal Ion Channel Expression in Post Infarction Remodeled Heart” (Ph.D. Physiology, 1998).

7.  Gamal Abdallah Ali: “Risk Stratification of Sudden Death Following Myocardial Infarction” (Ph.D. Physiology, Canal Suez University, 1998) ..

8.  Magda Helal Mohammed: “Risk Stratification of Patients for serious arrhythmic events after myocardial infarction by combinatorial non-invasive algorithm.” (PhD, Physiology, Alexandria University,1999)

9.  Lili Deng: “ Post-Infarction signal transduction pathways as targets for novel therapeutic interventions”, PhD in Molecular biology, 2004, SUNY Downstate Medical Center.

PREVIOUS AND CURRENT TRAINEES IN THE CARDIOVASCULAR RESEARCH LABORATORY OF DR. N. EL-SHERIF

Name

/
Period
/
Training
/ Funding Source / Current Position
William B, Gough, PhD / 1979-81 / Post-doc / NIH, Merit / Director, Applied Commun. Parsippany, NJ
Rahul Mehra, PhD / 1980-84 / Post-doc / NIH, Merit / Senior Scientist, Medtronic, Minneapolis, MN
Robert Zeiler, PhD / 1981-85 / Doc thesis* / NIH, Merit / Senior Scientist, Ayerst Wyeth, NJ
Mohamed Boutjdir, PhD / 1987-89 / Post-doc / NIH, Merit / Cardiovascular Physiologist, BVAMC
Mark Restivo, PhD / 1982-87 / Doc thesis* / NIH, Merit / Research Scientist, BVAMC
Hua Yang, PhD / 1988-90 / Post-doc / NIH / Biomed Eng, Henry Ford Hospital, Detroit, MI
Bulant Zaim, MD / 1988-91 / Post-doc / NIH / Cardiac Electrophysiologist, Washington DC
Mashid Assadi, MD / 1988-91 / Post-doc / NIH / Cardiology Consultant, Roosevelt Hospital, NY
Raphael Henkin, PhD / 1986-92 / Doc thesis* / NIH / Director, R&D, DelMar Avionics, Irvine, CA
Wolfgang Schoels, MD / 1990-92 / Post-doc / Deutsche Herz Gesellschaft / Director, EP Program, Univ. of Heidelburg, Germany
Dayi Qin, PhD / 1990-92 / Post-doc / NIH / Assist’ Prof of Physiology, SUNY, Bklyn, NY
Nidal Isber, MD / 1992-94 / Post-doc / NIH / Assist’ Prof of Medicine, Columbia Univ. NY
Alberico Sorgato, MD / 1993 / Post-doc / Italian Gov’t grant / Asst. Prof., Brescia, Italy
Ghazwan Butrous, MD / 1994-95 / Post-doc / NIH, Merit / Director, Clin. Res., Pfizer, England
Gjin Ndrepepa, MD / 1994-95 / Post-doc / Fulbright Grant / Cardiologist, Univ of Tirana, Albania
Alaa Abdelmeguid, MD / 1993-95 / Post-doc / Merit / Attending Card, Henry Ford Hos, Detroit, MI
Zhi Hao Zhang, PhD / 1993-95 / Post-doc / Merit / Res. Scientist, Wyeth-Ayerst Princeton, NJ
Shu Zhang, MD / 1995-96 / Post-doc / Proctor & Gamble / Director of EP, Univ. of Beijing, China
Maha Hegazy, MD, PhD / 1994-96 / Doc thesis* / Egyptian gov’t. / Asst. Prof Physiol, Alexandria Univ, Egypt
Edward Ben Caref, PhD / 1992-97 / Doc thesis* / NIH, Merit / Asst Res Prof, SUNYHSC
Bekir Cebeci, MD / 1996-97 / Post-doc / Turkish gov’t / Electrophysiology, Gulhama Academy, Turkey
Masaomi Chinushi, MD / 1996-98 / Post-doc / Medtronic Intn’l / Asst. Prof., Niigata, Japan
Boyu Huang, PhD / 1995-98 / Doc thesis* / SUNY HSC@B / Research Assoc., BVAMC
Gamal Al-Attar, MD / 1996-98 / Doc thesis* / Egyptian gov’t / Asst. Prof, Suez Canal Univ., Egypt
Magda Helal Mohamad / 1997-1999 / Doc thesis* / Egyptian gov’t / Asst. Prof, Assiut University, Egypt
Madhavi Gidh-Jain, PhD / 1995-97 / Post-doc / Merit / Research Scientist, Wyeth-Ayerst, NJ
Keiji Yamamoto, PhD / 1999-2000 / Post-doc / Takeda Ind grant / Research Scientist-Takeda Chem Ind, Japan
Ai Hongbin, M.D. / 1999-2000 / R.Scientist / China schlrshpCouncl / Professor,Biology Dept,Shandong Univ.PRC
* indicates PhD thesis completed in Dr. El-Sherif’s research laboratories; does not include CCEP trainees
Hala El-Adawi, PhD / 2000-2002 / Post-doc / VACO-REAP / Center for Molecular Biology,Alexandia,Egypt
Steven Smith, PhD / 2000-2002 / Research associate / VACO-REAP / Research Associate-SUNY Downstae Medical Center
Tamara Baynham, PhD / 2002-2003 / Research associate / VACO-REAP / Guidant Corp, Minneapolis, Mn
Anthony tramontano, MD / 2002-2004 / Researc associate / VACO-REAP / Cardiology fellow, SUNY/DS 2004-2006
Vikram Lakireddy, MD / 2003-2005 / Research Fellow / SUNY/DS
Gil Bub, PhD / 2004-2007 / Cardipovascular Physiologist / VACO-REAP
Denny Himel, PhD / 2007-2011 / Cardiovascular Phyiologist / Vaco REAP, MERIT
Praja Lakireddy, MD / 2011-2013 / Clinical/Research fellow / VA funds
Sajin Pilai, MD / 2013- / Clinical/Research fellow / VA funds

MAJOR RESEARCH FUNDING SUPPORT:

A. Federal Grants:

1. Research Associate, NIH-HLBI Contract 72-2972-M (1973-1974) Total funds $50,000.00

2. NIH-HLBI RO1HL 18139, 1975-1980 - "Mechanism of ischemic rhythm disorders." (Co-investigator-Principal investigator: Benjamin J. Scherlag, Ph.D.) Total Funds $350,100.00

3. VA Cooperative Study - "Aspirin Therapy and Unstable Angina", 1976-1978, (Principal Investigator) Total Funds $76,956.00

4. VA Merit Grant - "Conduction Disorder in Myocardial Infarction", (Principal Investigator) 1976-1979. Total Funds $70,400.00

5. VA Merit Grant - "Antiarrhythmic and Autonomic drugs in ischemic reentrant rhythms", 1979-1982, (Principal Investigator) Total funds $136,000.00

6. VA Merit Grant - "Electrophysiology and Pharmacology of Ischemia- Related Ventricular Rhythms", 1982-1986, (Principal Investigator) Total Funds $373,000.00

7. VA Merit Grant - "Study of Diastolic Activity on the Body Surface in Ischemic heart Disease", 1982-1985, (Principal Investigator) Total funds $86,000.00

8. VA Merit Grant - "Electrograms of the Sinus Node and other Cardiac Pacemakers", 1982-1985, (Co-principal Investigator) Total Funds $90,000.00

9. NIH-HLBI-RO1 HL31341: "A low noise electrocardiogram in ventricular arrhythmias." December 1983 - November 1986. (Principal Investigator) Total Funds $177,641.

10. VA Merit Grant "Electrophysiology of Triggered Rhythms Post-Infarction in canine Heart" 1985-1988 (Co-Principal Investigator) Total Funds $188,000.

11. VA Merit Grant "Effects of Amphiphiles on the Contractility of Cultured Cardiac Myocytes" 1986-1989 (Co-Principal Investigator) Total Funds $88,000.

12. VA Merit Grant "Correlation of Activation and Refractory Patterns of Reentrant Excitation" 1986-1991 (Principal Investigator) Total Funds $600,000.

13. NIH-HLB1-RO1 HL 36680: Activation Patterns of Reentrant Rhythms. July 1986-June 1991 (Principal Investigator) Total Funds $608,223.

14. NIH-HLB1-HC-85-20: "Cardiac Arrhythmia Treatment Study" - Clinical Center. August 14, 1986 - December 31, 1992. (Principal Investigator) Total Funds $1,112,000.

15. NIH-HLBI-R01 HL 31341: "A low noise electrocardiogram in ventricular arrhythmias." (Renewal) December 1986-November 1989 (Principal Investigator) Total Funds $270,000.

16. NIH-HLBI-HC-91-: "Multicenter Unsustained Tachycardia Trial" (MUSTT) 10/1/1991 - 9/30/1996 (Pricipal Investigator, participating Center) Total funds $317,000.

17. VA Merit grant: "Electrophysiology of circus movement atrial flutter." Oct. 1991 - Sept. 1996 (Principal Investigator). Total funds $610,000.

18. VA Merit Grant: "A model of propagation and electrical activity in reentrant circuits". April 1991 - March 1994. (Co-Principal Investigator) Total funds $450,000.

19. VACO-Cooperative Study: " Warfarin and aspirin in secondary prevention." August 1992-June 1998, (Principal Investigator, partcipating center). Total funds $310,000.

20. VA Merit Grant: "Adrenergic regulation of cardiac calcium channels". April 1994 - March 1997 (Co-Principal Investigator) Total funds $275,800.

21. American Heart Association: Grant-in-Aid: “IgG from mothers whose children have congenital heart block inhibit voltage-gated cardiac calcium channels” 1996-1999 (Co-PI) Total funds $120,000.

22. NIH-HLB1-R0156650: “Cellular mechanisms of auto immune associated congenital heart block” 1996-2000 (Co-PI): Total funds $840,000.

23. VA Merit Grant: “Optical Mapping of early afterdepolarization in the long QT Syndrome” 1996-1998.

(Co-PI): Total funds $300,000.

24.  VA Merit Grant: Molecular and electrophysiological basis of post-infarction remodeling” 1996-2003. Principal Investigator. Total funds $450,000.

25.  VACO-Cooperative study #399: “The affects of anti-arrhythmic therapy on maintaining stability of sinus rhythm in atrial fibrillation” (Principarl Investigator, participating center) 1998-2003, Total funds $150,000.

26.  VACO-REAP: “Cardiac Remodeling and Arrhythmogenesis” Principal Investigator 2000-2005-$3,417,000.

27.  NIH-HLBI-RO1-074869. Calcium Kinetics& Arhythmias in hypertrophy+Ischemia. Principal Investigator, 2004-2009. Total direct funds :1,250,000. Pending

28.  NIH-Centers of Excellence-Resource-Related Research Grants, R24. PI-Research Core.

2004-2007. Total direct funds: $ 825,000

29. VA MERIT grant: “Altered Calcium kinetics and arrhythmogenesis in ischemia/reperfusion”. Principal

Investigator. 2004-2009. Total funds $800,000.

B. Non-Federal Grants:

1. "Lopressor Intervention Trial." Ciba-Geigy, 1979-1982, (Principal Investigator) Total Funds $151,400.00

2. "Comparison Between Tined Porous and Tined Standard Endocardial pacing Leads." 1979-1981, (Principal Investigator) Pacesetter, Total Funds $11,000.00

3. "Value of Endocardial Electrograms in Early Detection of Pacemaker Failure." 1981-1982, Medtronics, Inc. Total Funds $5,000.00

4. "Cardiovascular effects of Amoxapine." 1982-1983, (Principal Investigator) American Cyanamid Company, Total Funds $25,000.00

5. "Labetalol and Hydrochlorothiazide Trial in Moderate to Moderately Severe Essential Hypertension." 1982-1983, (Principal Investigator) Schering Corp. Total Funds $56,000.00