SUPPLEMENTARY MATERIALS

Nucleotide Selectivity in Abiotic RNA Polymerization Reactions

Kristin M. Coari, Rebecca C. Martin, Kopal Jain and Linda B. McGown*

The New York Center for Astrobiology and the Department of Chemistry and Chemical Biology

Rensselaer Polytechnic Institute

110 8th Street, Troy, NY, 12180 U.S.A.

*

TEL: +1 518-276-3681

FAX: +1 518-276-4776


Figure S2. MALDI MS spectra of reaction products for mixtures of ImpG with each of the individual XMP, showing full spectrum from trimers forward. Boxed area shows trimer region that is shown on an expanded scale in Figure S3.

Figure S3. MALDI MS spectra of reaction products in the trimer region for mixtures of ImpG with each of the individual XMP.

Figure S4. MALDI MS spectra of reaction products in the tetramer region for mixtures of ImpG with multiple XMP.

Figure S5. MALDI MS spectra of reaction products for mixtures of ImpI with each of the individual XMP, showing full spectrum from trimers forward.

Figure S6. MALDI MS spectra of reaction products in the tetramer region for mixtures of ImpI with each of the individual XMP.

Figure S7. MALDI MS spectra of reaction products in the tetramer region for mixtures of ImpI with multiple XMP.

Figure S8. MALDI MS spectra of reaction products for mixtures of ImpC with each of the individual XMP, showing full spectrum from trimers forward. Boxed area shows tetramer region that is shown on an expanded scale in Figure S9.

Figure S9. MALDI MS spectra of reaction products in the tetramer region for mixtures of ImpC with each of the individual XMP.


Figure S10. MALDI MS spectra of reaction products in the tetramer region for mixtures of ImpC with multiple XMP.

Figure S11. MALDI MS spectra of reaction products for mixtures of ImpU with each of the individual XMP, showing full spectrum from trimers forward. Boxed area shows tetramer region that is shown on an expanded scale in Figure S12.

Figure S12. MALDI MS spectra of reaction products in the tetramer region for mixtures of ImpU with each of the individual XMP.

Figure S13. MALDI MS spectra of reaction products in the trimer region for mixtures of ImpU with each of the individual XMP.

Figure S14. MALDI MS spectra of reaction products in the trimer region for mixtures of two ImpX.

Figure S15. MALDI MS spectra of reaction products for individual, in situ-activated XMP, showing full spectra region from trimers forward.

Figure S16. MALDI MS spectra of reaction products for mixtures of two in situ-activated XMP, showing full spectral region from trimers forward.

Figure S17. MALDI MS spectra of reaction products for mixtures of two in situ-activated XMP, showing full spectral region from trimers forward.

Figure S18. MALDI MS spectra of reaction products in trimer region for mixtures of three in situ-activated XMP.

Figure S19. MALDI MS spectra of reaction products in trimer region for mixtures of three in situ-activated XMP.

Figure S20. MALDI MS spectra of reaction products in trimer region for mixtures of three in situ-activated XMP.

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