Supplemental Table 1: Potential Confounding Covariates by Sex and Cumulative Extremely

Supplemental table 1: Potential confounding covariates by sex and cumulative Extremely Low Frequency Magnetic Field exposure in the subcohort

Men / Women
Background / > 0 - 21.5 unit - years / > 21.5 - 38.1 unit-years / > 38.1 - 204 unit-years / Background / > 0 – 6.5 unit - years / > 6.5 - 11 unit-years / > 11 - 136 unit-years
No. / % / mean
(sd) / No. / % / mean
(sd) / No. / % / mean
(sd) / No. / % / mean
(sd) / No. / % / mean (sd) / No. / % / mean (sd) / No. / % / mean (sd) / No. / % / mean (sd)
Cigarette smoker (%)
never smoked / 150 / 14.6 / 40 / 11.1 / 43 / 12.2 / 34 / 8.9 / 620 / 60.1 / 181 / 54.2 / 206 / 60.4 / 184 / 53.5
ex-smoker / 492 / 47.8 / 187 / 51.8 / 181 / 51.4 / 226 / 59.0 / 192 / 18.6 / 82 / 24.6 / 69 / 20.2 / 81 / 23.5
current smoker / 388 / 37.7 / 134 / 37.1 / 128 / 36.4 / 123 / 32.1 / 219 / 21.2 / 71 / 21.3 / 66 / 19.4 / 79 / 23.0
Number of cigarettes smoked per day
(mean (sd)) / 961 / 14.9
(11.8) / 343 / 15.3
(12.0) / 337 / 14.7
(10.8) / 361 / 14.0
(10.2) / 1010 / 4.2
(7.4) / 326 / 5.0
(7.8) / 335 / 4.4
(7.3) / 337 / 5.6
(8.8)
Number of years smoking cigarettes
(mean (sd)) / 1012 / 28.8
(16.4) / 356 / 29.4
(15.3) / 346 / 29.6
(15.6) / 375 / 30.5
(14.8) / 1018 / 11.1
(16.0) / 331 / 12.3
(16.0) / 339 / 10.7
(15.3) / 340 / 12.9
(16.2)
Body Mass Index
(kg / m2; mean (sd)) / 997 / 25.0
(2.7) / 351 / 24.7
(2.5) / 342 / 25.0
(2.5) / 367 / 24.9
(2.6) / 1002 / 24.8
(3.5) / 326 / 25.6
(3.6) / 327 / 25.5
(3.7) / 332 / 25.0
(3.4)
Alcohol consumption
(gr/day; mean (sd)) / 1008 / 15.9
(17.6) / 350 / 16.1
(16.9) / 345 / 13.7
(17.2) / 380 / 12.9
(14.0) / 981 / 6.6
(10.1) / 320 / 5.0
(8.9) / 319 / 5.8
(9.1) / 319 / 5.5
(8.7)
Attained education level(%)
Primary vocational / 290 / 28.2 / 86 / 24 / 82 / 23.4 / 94 / 24.5 / 296 / 28.8 / 112 / 33.8 / 132 / 38.7 / 119 / 34.9
Lower vocational / 162 / 15.8 / 69 / 19.3 / 85 / 24.2 / 119 / 31.1 / 221 / 21.5 / 85 / 25.7 / 87 / 25.5 / 70 / 20.5
Secondary and medium vocational / 324 / 31.5 / 143 / 39.9 / 127 / 36.2 / 143 / 37.3 / 357 / 34.7 / 122 / 36.9 / 116 / 34.0 / 136 / 39.9
Higher vocational / 251 / 24.4 / 60 / 16.8 / 57 / 16.2 / 27 / 7.0 / 154 / 15.0 / 12 / 3.6 / 6 / 1.8 / 16 / 4.7
Fruit consumption
(gr/day; mean (sd)) / 975 / 151
(112) / 439 / 154
(123) / 332 / 154
(96) / 369 / 161
(115) / 991 / 199
(121) / 319 / 198
(117) / 320 / 193
(120) / 324 / 189
(114)
Cumulative occupational asbestos exposure (%)
No exposure / 798 / 77.6 / 209 / 58.1 / 241 / 68.1 / 254 / 66.1 / 1,011 / 98.4 / 321 / 96.1 / 340 / 99.1 / 341 / 98.6
1sttertile / 65 / 6.3 / 73 / 20.3 / 34 / 9.6 / 28 / 7.3 / 1 / 0.1 / 8 / 2.4 / 1 / 0.3 / 1 / 0.3
2ndtertile / 81 / 7.9 / 58 / 16.1 / 38 / 10.7 / 39 / 10.2 / 8 / 0.8 / 4 / 1.2 / 1 / 0.3 / 1 / 0.3
3rdtertile / 84 / 8.2 / 20 / 5.6 / 41 / 11.6 / 63 / 16.4 / 7 / 0.7 / 1 / 0.3 / 1 / 0.3 / 3 / 0.9
Cumulative occupational total solventexposure(%)
No exposure / 763 / 74.1 / 196 / 54.3 / 194 / 55.1 / 196 / 51.2 / 977 / 94.8 / 321 / 96.1 / 335 / 98.2 / 324 / 94.2
1sttertile / 92 / 8.9 / 102 / 28.3 / 27 / 7.7 / 24 / 6.3 / 8 / 0.8 / 11 / 3.3 / 1 / 0.3 / 4 / 1.2
2ndtertile / 129 / 12.5 / 31 / 8.6 / 53 / 15.1 / 53 / 13.8 / 27 / 2.6 / 0 / 0 / 4 / 1.2 / 7 / 2
3rdtertile / 46 / 4.5 / 32 / 8.9 / 78 / 22.2 / 110 / 28.7 / 19 / 1.8 / 2 / 0.6 / 1 / 0.3 / 9 / 2.6
Cumulative occupational aromatic solvent exposure (%)
No exposure / 800 / 77.7 / 211 / 58.4 / 207 / 58.8 / 229 / 59.8 / 773 / 75 / 299 / 89.5 / 311 / 91.2 / 287 / 83.4
1sttertile / 64 / 6.2 / 101 / 28.0 / 20 / 5.7 / 34 / 8.9 / 72 / 7.0 / 18 / 5.4 / 9 / 2.6 / 14 / 4.1
2ndtertile / 56 / 5.4 / 40 / 11.1 / 93 / 26.4 / 40 / 10.4 / 100 / 9.7 / 10 / 3.0 / 9 / 2.6 / 18 / 5.2
3rdtertile / 110 / 10.7 / 9 / 2.5 / 32 / 9.1 / 80 / 20.9 / 86 / 8.3 / 7 / 2.1 / 12 / 3.5 / 25 / 7.3
Family history of hematological malignancies(%)
No / 1,001 / 97.2 / 350 / 97.0 / 348 / 98.9 / 379 / 99.0 / 995 / 96.5 / 322 / 96.4 / 333 / 97.7 / 332 / 96.5
Yes / 29 / 2.8 / 11 / 3.0 / 4 / 1.1 / 4 / 1.0 / 36 / 3.5 / 12 / 3.6 / 8 / 2.3 / 12 / 3.5
Family history of breast cancer(%)
No / 923 / 89.9 / 297 / 88.9 / 324 / 94.5 / 325 / 93.9
Yes / 104 / 10.1 / 37 / 11.1 / 19 / 5.5 / 21 / 6.1
History of benign breast growth(%)
No / 939 / 91.4 / 311 / 93.1 / 320 / 93.3 / 323 / 93.4
Yes / 88 / 8.6 / 23 / 6.9 / 23 / 6.7 / 23 / 6.6
Age at menarche
(years: mean (sd)) / 1014 / 13.6
(1.7) / 333 / 13.7
(1.7) / 340 / 13.8
(1.9) / 339 / 13.8
(1.8)
Age at menopause
(years: mean (sd)) / 946 / 48.7
(4.5) / 310 / 48.3
(4.6) / 323 / 48.4
(4.7) / 324 / 48.7
(4.4)
Parity + age at first child(%)
nulliparae / 229 / 22.7 / 27 / 8.2 / 34 / 10 / 93 / 27.4
1-2 children, 1st child <25 / 51 / 5.1 / 28 / 8.5 / 16 / 4.7 / 24 / 7.1
1-2 children, 1st child >=25 / 207 / 20.5 / 70 / 21.1 / 111 / 32.7 / 90 / 26.5
>=3 children, 1st child <25 / 146 / 14.5 / 102 / 30.8 / 48 / 14.2 / 32 / 9.4
>=3 children, 1st child >=25 / 375 / 37.2 / 104 / 31.4 / 130 / 38.3 / 101 / 29.7

Supplemental table 2: Association between occupational Extremely Low Frequency Magnetic Fields Exposure and Subtypes of breast cancer, Women only

Men
Cases / Person-years in subcohort / Adjusted HR / 95% Confidence Interval
Ductal Carcinomasa
Ever exposed / Background / 689 / 13,064 / reference
Low / 710 / 13,069 / 1.08 / (0.93 - 1.26)
High / 11 / 203 / 1.14 / (0.51 - 2.55)
Duration of exposure / HR / 10 years / 861 / 15,877 / 0.98 / (0.86 - 1.12)
Cumulative exposure / Background / 692 / 13,064 / reference
1st tertileb / 273 / 4,473 / 1.27 / (1.03 - 1.58)
2nd tertileb / 193 / 4,454 / 0.88 / (0.70 - 1.09)
3rd tertileb / 252 / 4,345 / 1.09 / (0.88 - 1.34)
Test for trend / 1,410 / 26,336 / p = 0.57
Lobular Carcinomasa
Ever exposed / Background / 197 / 13,360 / reference
Low / 143 / 12,612 / 1.38 / (1.05 - 1.81)
High / 38 / 2,187 / 0.83 / (0.11 - 6.58)
Duration of exposure / HR / 10 years / 160 / 15,877 / 0.88 / (0.67 - 1.14)
Cumulative exposure / Background / 197 / 13,373 / reference
1st tertileb / 52 / 4,828 / 1.78 / (1.23 - 2.58)
2nd tertileb / 70 / 4,865 / 1.21 / (0.81 - 1.79)
3rd tertileb / 59 / 5,092 / 1.12 / (0.75 - 1.67)
Test for trend / 378 / 28,158 / p = 0.41
Estrogen Receptor Status Positive Carcinomaa
Ever exposed / Background / 416 / 13,064 / reference
Low / 408 / 13,069 / 1.04 / (0.87 - 1.24)
High / 8 / 203 / 1.42 / (0.59 - 3.40)
Duration of exposure / HR / 10 years / 498 / 15,877 / 0.93 / (0.80 - 1.09)
Cumulative exposure / Background / 418 / 13,116 / reference
1st tertileb / 160 / 4,421 / 1.26 / (0.99 - 1.62)
2nd tertileb / 116 / 4,471 / 0.90 / (0.69 - 1.16)
3rd tertileb / 138 / 4,328 / 0.99 / (0.77 - 1.26)
Test for trend / 832 / 26,336 / p = 0.90
HR: Hazard Ratio, NC: Not calculated
a)Corrected for alcohol intake, body mass index, fruit intake, age at menarche, age at menopause, parity, age at first child, number of children, benign breast growth, and family history of breast cancer
b) Sex specific cut-points; Men: 1sttertile: >0 – 21.5 unit-years, 2ndtertile: >21.5 – 38.1 unit-years, 3rdtertile: >38.1 – 204 unit-years; Women: 1sttertile: >0 – 6.5 unit-years, 2ndtertile: >6.5 – 11 unit-years, 3rdtertile: >11 – 136 unit-years

Supplemental table 3: Association between occupational Extremely Low Frequency Magnetic Fields Exposure and Subtypes of Brain Cancer, Stratified by Sex

Men / Women
Cases / Person-years in subcohort / Adjusted HR / 95% Confidence Interval / Cases / Person-years in subcohort / Adjusted HR / 95% Confidence Interval
AstrocyticGliomasa
Ever exposed / Background / 57 / 14,644 / reference / 32 / 15,962 / reference
Low / 52 / 13,474 / 0.99 / (0.67 - 1.45) / 23 / 15,892 / 0.72 / (0.42 - 1.24)
High / 7 / 2,335 / 0.77 / (0.34 - 1.71) / 0 / 253 / NC / NC
Duration of exposure / HR / 10 years / 59 / 15,809 / 1.02 / (0.85 - 1.22) / 23 / 16,145 / 0.79 / (0.51 - 1.24)
Cumulative exposure / Background / 57 / 14,658 / reference / 32 / 16,031 / reference
1st tertileb / 20 / 5,183 / 0.99 / (0.59 - 1.67) / 8 / 5,242 / 0.76 / (0.35 - 1.67)
2nd tertileb / 20 / 5,126 / 1.00 / (0.59 - 1.69) / 7 / 5,432 / 0.65 / (0.28 - 1.49)
3rd tertileb / 19 / 5,486 / 0.88 / (0.52 - 1.50) / 8 / 5,402 / 0.74 / (0.34 - 1.62)
Test for trend / 116 / 30,452 / p = 0.97 / 55 / 32,106 / p = 0.27
HR: Hazard Ratio, NC: Not calculated
a) No potential confounders showed a significant effect on brain cancer
b) Sex specific cut-points; Men: 1sttertile: >0 – 21.5 unit-years, 2ndtertile: >21.5 – 38.1 unit-years, 3rdtertile: >38.1 – 204 unit-years; Women: 1sttertile: >0 – 6.5 unit-years, 2ndtertile: >6.5 – 11 unit-years, 3rdtertile: >11 – 136 unit-years

Supplemental table 4: Association between occupational Extremely Low Frequency Magnetic Fields Exposure and Lineages of Non-Hodgkin Lymphoma Incidence, Stratified by Sex

Men / Women
Cases / Person-years in subcohort / Adjusted HR / 95% Confidence Interval / Cases / Person-years in subcohort / Adjusted HR / 95% Confidence Interval
Non-Hodgkin Lymphoma, B-cell
Ever exposed / Background / 328 / 14,576 / reference / 247 / 15,901 / reference
Low / 331 / 13,418 / 1.10 / (0.92 - 1.32) / 211 / 15,875 / 0.88 / (0.71 - 1.08)
High / 61 / 2,296 / 1.25 / (0.90 - 1.73) / 4 / 253 / 0.94 / (0.30 - 2.91)
Duration of exposure / HR / 10 years / 392 / 15,714 / 0.99 / (0.92 - 1.08) / 215 / 16,128 / 0.99 / (0.83 - 1.18)
Cumulative exposure / Background / 329 / 14,590 / reference / 247 / 15,971 / reference
1st tertileb / 128 / 5,165 / 1.09 / (0.86 - 1.39) / 77 / 5,234 / 0.99 / (0.74 - 1.31)
2nd tertileb / 133 / 5,118 / 1.25 / (0.98 - 1.59) / 73 / 5,424 / 0.91 / (0.68 - 1.21)
3rd tertileb / 130 / 5,418 / 1.02 / (0.80 - 1.30) / 65 / 5,401 / 0.77 / (0.57 - 1.05)
Test for trend / 720 / 30,290 / p = 0.38 / 462 / 32,029 / p = 0.05
Follicular Lymphomaa
Ever exposed / Background / 20 / 14,576 / reference / 23 / 15,901 / reference
Low / 22 / 13,418 / 1.23 / (0.67 - 2.28) / 21 / 15,875 / 0.94 / (0.51 - 1.71)
High / 7 / 2,296 / 2.78 / (1.20 - 6.44) / 1 / 253 / 2.68 / (0.33 - 21.70)
Duration of exposure / HR / 10 years / 30 / 15,714 / 1.04 / (0.81 - 1.35) / 22 / 16,128 / 0.96 / (0.59 - 1.58)
Cumulative exposure / Background / 20 / 14,590 / reference / 23 / 15,971 / reference
1st tertileb / 8 / 5,165 / 1.14 / (0.50 - 2.61) / 6 / 5,234 / 0.82 / (0.33 - 2.06)
2nd tertileb / 8 / 5,118 / 1.23 / (0.54 - 2.80) / 8 / 5,424 / 1.07 / (0.47 - 2.43)
3rd tertileb / 13 / 5,418 / 1.97 / (0.98 - 3.95) / 8 / 5,401 / 1.02 / (0.45 - 2.31)
Test for trend / 49 / 30,290 / p = 0.03 / 45 / 32,029 / p = 0.70
Chronic Lymphocytic Leukemia / Small lymphocytic lymphoma
Ever exposed / Background / 68 / 14,576 / reference / 41 / 15,901 / reference
Low / 70 / 13,418 / 1.11 / (0.78 - 1.58) / 33 / 15,875 / 0.83 / (0.52 - 1.32)
High / 10 / 2,296 / 0.98 / (0.49 - 1.97) / 1 / 253 / 1.48 / (0.19 - 11.75)
Duration of exposure / HR / 10 years / 80 / 15,714 / 0.94 / (0.81 - 1.08) / 34 / 16,128 / 0.91 / (0.62 - 1.33)
Cumulative exposure / Background / 68 / 14,590 / reference / 41 / 15,971 / reference
1st tertileb / 30 / 5,165 / 1.24 / (0.79 - 1.93) / 12 / 5,234 / 0.93 / (0.48 - 1.79)
2nd tertileb / 26 / 5,118 / 1.17 / (0.72 - 1.89) / 11 / 5,424 / 0.82 / (0.42 - 1.62)
3rd tertileb / 24 / 5,418 / 0.91 / (0.56 - 1.48) / 11 / 5,401 / 0.79 / (0.40 - 1.55)
Test for trend / 148 / 30,290 / p = 0.63 / 75 / 32,029 / p = 0.68
Diffuse large B-cell lymphoma
Ever exposed / Background / 74 / 14,576 / reference / 55 / 15,901 / reference
Low / 75 / 13,418 / 1.11 / (0.79 - 1.56) / 37 / 15,875 / 0.69 / (0.45 - 1.06)
High / 15 / 2,296 / 1.37 / (0.75 - 2.48) / 1 / 253 / 1.02 / (0.13 - 8.06)
Exposure duration / HR / 10 years / 90 / 15,714 / 1.07 / (0.93 - 1.23) / 38 / 16,128 / 1.19 / (0.85 - 1.66)
Cumulative exposure / Background / 74 / 14,590 / reference / 55 / 15,971 / reference
1st tertileb / 27 / 5,165 / 1.02 / (0.64 - 1.62) / 11 / 5,234 / 0.64 / (0.33 - 1.23)
2nd tertileb / 32 / 5,118 / 1.41 / (0.90 - 2.19) / 15 / 5,424 / 0.84 / (0.47 - 1.51)
3rd tertileb / 31 / 5,418 / 1.07 / (0.69 - 1.66) / 12 / 5,401 / 0.64 / (0.34 - 1.21)
Test for trend / 164 / 30,290 / p = 0.29 / 93 / 32,029 / p = 0.15
Multiple Myeloma
Ever exposed / Background / 87 / 14,576 / reference / 83 / 15,901 / reference
Low / 93 / 13,418 / 1.16 / (0.85 - 1.57) / 76 / 15,875 / 0.94 / (0.68 - 1.30)
High / 15 / 2,296 / 1.14 / (0.64 - 2.02) / 1 / 253 / 0.71 / (0.09 - 5.56)
Exposure duration / HR / 10 years / 108 / 15,714 / 1.00 / (0.86 - 1.15) / 77 / 16,128 / 0.84 / (0.60 - 1.18)
Cumulative exposure / Background / 88 / 14,590 / reference / 83 / 15,971 / reference
1st tertileb / 33 / 5,165 / 1.06 / (0.69 - 1.61) / 34 / 5,234 / 1.29 / (0.85 - 1.97)
2nd tertileb / 40 / 5,118 / 1.37 / (0.92 - 2.04) / 21 / 5,424 / 0.77 / (0.47 - 1.27)
3rd tertileb / 34 / 5,418 / 1.00 / (0.66 - 1.51) / 22 / 5,401 / 0.78 / (0.48 - 1.27)
Test for trend / 195 / 30,290 / p = 0.47 / 160 / 32,029 / p = 0.17
HR: Hazard Ratio, NC: Not calculated
a) Corrected for family history of hematological malignancies
b) Sex specific cut-points; Men: 1sttertile: >0 – 21.5 unit-years, 2ndtertile: >21.5 – 38.1 unit-years, 3rdtertile: >38.1 – 204 unit-years; Women: 1sttertile: >0 – 6.5 unit-years, 2ndtertile: >6.5 – 11 unit-years, 3rdtertile: >11 – 136 unit-years

Supplemental table 5: Association between occupational Extremely Low Frequency Magnetic Fields Exposure and Subtypes of Lung Cancer Incidence, Stratified by Sex

Men / Women
Cases / Person-years in subcohort / Adjusted HR / 95% Confidence Interval / Cases / Person-years in subcohort / Adjusted HR / 95% Confidence Interval
Large Cell Carcinomaa
Ever exposed / Background / 147 / 13,360 / reference / 28 / 15,407 / reference
Low / 157 / 12,612 / 1.10 / (0.84 - 1.43) / 31 / 15,469 / 1.02 / (0.59 - 1.78)
High / 46 / 2,187 / 1.71 / (1.11 - 2.62) / 2 / 220 / 3.42 / (0.58 - 20.07)
Exposure duration / HR / 10 years / 214 / 15,753 / 1.00 / (0.89 - 1.13) / 34 / 16,181 / 1.20 / (0.84 - 1.71)
Cumulative exposure / Background / 147 / 13,373 / reference / 28 / 15,476 / reference
1st tertileb / 59 / 4,828 / 1.05 / (0.72 - 1.52) / 11 / 5,024 / 1.07 / (0.47 - 2.42)
2nd tertileb / 71 / 4,865 / 1.37 / (0.98 - 1.92) / 6 / 5,344 / 0.64 / (0.26 - 1.62)
3rd tertileb / 73 / 5,092 / 1.15 / (0.82 - 1.61) / 16 / 5,253 / 1.39 / (0.73 - 2.66)
Test for trend / 350 / 28,158 / p = 0.23 / 61 / 31,096 / p = 0.61
Small Cell Carcinomaa
Ever exposed / Background / 197 / 13,360 / reference / 34 / 15,407 / reference
Low / 143 / 12,612 / 0.73 / (0.56 - 0.95) / 42 / 15,469 / 1.14 / (0.69 - 1.90)
High / 38 / 2,187 / 0.96 / (0.61 - 1.51) / 0 / 220 / 0.00 / (0.00 - 0.00)
Duration of exposure / HR / 10 years / 207 / 15,753 / 1.04 / (0.91 - 1.19) / 44 / 16,181 / 0.99 / (0.70 - 1.40)
Cumulative exposure / Background / 197 / 13,373 / reference / 34 / 15,476 / reference
1st tertileb / 52 / 4,828 / 0.66 / (0.45 - 0.97) / 16 / 5,024 / 1.45 / (0.74 - 2.84)
2nd tertileb / 70 / 4,865 / 0.93 / (0.67 - 1.29) / 14 / 5,344 / 1.18 / (0.59 - 2.36)
3rd tertileb / 59 / 5,092 / 0.71 / (0.50 - 1.01) / 12 / 5,253 / 0.81 / (0.39 - 1.70)
Test for trend / 378 / 28,158 / p = 0.12 / 76 / 31,096 / p = 0.60
Squamous Cell Carcinomaa
Ever exposed / Background / 435 / 13,360 / reference / 50 / 15,407 / reference
Low / 391 / 12,612 / 0.90 / (0.74 - 1.09) / 53 / 15,469 / 0.95 / (0.61 - 1.49)
High / 105 / 2,187 / 1.22 / (0.88 - 1.69) / 2 / 220 / 1.10 / (0.19 - 6.30)
Duration of exposure / HR / 10 years / 553 / 15,753 / 0.99 / (0.90 - 1.09) / 59 / 16,181 / 0.98 / (0.70 - 1.39)
Cumulative exposure / Background / 436 / 13,373 / reference / 50 / 15,476 / reference
1st tertileb / 163 / 4,828 / 0.96 / (0.74 - 1.24) / 20 / 5,024 / 1.22 / (0.67 - 2.21)
2nd tertileb / 148 / 4,865 / 0.89 / (0.69 - 1.14) / 14 / 5,344 / 0.82 / (0.42 - 1.60)
3rd tertileb / 184 / 5,092 / 0.99 / (0.77 - 1.26) / 21 / 5,253 / 0.88 / (0.48 - 1.60)
Test for trend / 931 / 28,158 / p = 0.55 / 105 / 31,096 / p = 0.63
Adenocarcinomaa
Ever exposed / Background / 219 / 13,360 / reference / 59 / 15,407 / reference
Low / 214 / 12,612 / 1.05 / (0.83 - 1.32) / 54 / 15,469 / 0.94 / (0.62 - 1.41)
High / 59 / 2,187 / 1.67 / (1.14 - 2.44) / 1 / 220 / 0.98 / (0.11 - 8.37)
Duration of exposure / HR / 10 years / 299 / 15,753 / 1.02 / (0.92 - 1.13) / 58 / 16,181 / 1.01 / (0.73 - 1.41)
Cumulative exposure / Background / 219 / 13,373 / reference / 59 / 15,476 / reference
1st tertileb / 80 / 4,828 / 1.01 / (0.73 - 1.38) / 17 / 5,024 / 0.97 / (0.54 - 1.73)
2nd tertileb / 97 / 4,865 / 1.25 / (0.93 - 1.67) / 20 / 5,344 / 1.12 / (0.65 - 1.92)
3rd tertileb / 96 / 5,092 / 1.13 / (0.84 - 1.53) / 18 / 5,253 / 0.79 / (0.44 - 1.41)
Test for trend / 492 / 28,158 / p = 0.25 / 114 / 31,096 / p = 0.17
HR: Hazard Ratio
a) Corrected for smoking (current vs. non-current), number of cigarettes smoked per day, years of smoking cigarettes, attained level of education (primary vocational, lower vocational, secondary and medium vocational, higher vocational) and occupational asbestos exposure
b) Sex specific cut-points; Men: 1sttertile: >0 – 21.5 unit-years, 2ndtertile: >21.5 – 38.1 unit-years, 3rdtertile: >38.1 – 204 unit-years; Women: 1sttertile: >0 – 6.5 unit-years, 2ndtertile: >6.5 – 11 unit-years, 3rdtertile: >11 – 136 unit-years